{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:44:28Z","timestamp":1789598668921,"version":"build-2803163510"},"reference-count":47,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T00:00:00Z","timestamp":1726272000000},"content-version":"am","delay-in-days":349,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.jhep.2023.05.042","type":"journal-article","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T02:03:17Z","timestamp":1694743397000},"page":"1006-1014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Machine learning for individualized prediction of hepatocellular carcinoma development after the eradication of hepatitis C virus with antivirals"],"prefix":"10.1016","volume":"79","author":[{"given":"Tatsuya","family":"Minami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5423-9664","authenticated-orcid":false,"given":"Masaya","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1652-6168","authenticated-orcid":false,"given":"Hidenori","family":"Toyoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6312-5706","authenticated-orcid":false,"given":"Tomoharu","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5727-5385","authenticated-orcid":false,"given":"Takuma","family":"Nakatsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Enooku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayato","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4170-5923","authenticated-orcid":false,"given":"Hidetaka","family":"Fujinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4794-4418","authenticated-orcid":false,"given":"Masashi","family":"Izumiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2869-2881","authenticated-orcid":false,"given":"Motoyuki","family":"Otsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4275-468X","authenticated-orcid":false,"given":"Takamasa","family":"Ohki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6312-6319","authenticated-orcid":false,"given":"Masahiro","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-8226","authenticated-orcid":false,"given":"Yoshinari","family":"Asaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6358-5283","authenticated-orcid":false,"given":"Atsushi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyomi","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itsuro","family":"Ogata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Kamoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Nakagomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Akamatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Mitsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Fujie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Ogura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Uchino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1178-8748","authenticated-orcid":false,"given":"Hideo","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyuki","family":"Hanajiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonori","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohiko","family":"Kurai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisato","family":"Maekawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3525-4708","authenticated-orcid":false,"given":"Shuntaro","family":"Obi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5270-0752","authenticated-orcid":false,"given":"Takuma","family":"Teratani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiko","family":"Masaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayo","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5812-2818","authenticated-orcid":false,"given":"Naoya","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yotsuyanagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoji","family":"Moriya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-495X","authenticated-orcid":false,"given":"Takashi","family":"Kumada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4074-1140","authenticated-orcid":false,"given":"Mitsuhiro","family":"Fujishiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9787-1907","authenticated-orcid":false,"given":"Kazuhiko","family":"Koike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3021-2517","authenticated-orcid":false,"given":"Ryosuke","family":"Tateishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2023.05.042_bib1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S2468-1253(16)30181-9","article-title":"Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study","volume":"2","year":"2017","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib2","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1053\/j.gastro.2011.12.061","article-title":"Epidemiology of viral hepatitis and hepatocellular carcinoma","volume":"142","author":"El-Serag","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2023.05.042_bib3","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1002\/hep.27969","article-title":"World-wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma","volume":"62","author":"de Martel","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2023.05.042_bib4","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1056\/NEJMoa020047","article-title":"Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection","volume":"347","author":"Fried","year":"2002","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib5","doi-asserted-by":"crossref","first-page":"346","DOI":"10.7326\/0003-4819-140-5-200403020-00010","article-title":"Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose","volume":"140","author":"Hadziyannis","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib6","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1056\/NEJMoa1402454","article-title":"Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection","volume":"370","author":"Afdhal","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib7","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/S1473-3099(17)30496-6","article-title":"Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open-label, multicentre phase 3 trial","volume":"17","author":"Forns","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jhep.2023.05.042_bib8","doi-asserted-by":"crossref","first-page":"174","DOI":"10.7326\/0003-4819-131-3-199908030-00003","article-title":"Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT Study Group. Inhibition of hepatocarcinogenesis by interferon therapy","volume":"131","author":"Yoshida","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jhep.2017.08.030","article-title":"HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma","volume":"68","author":"Ioannou","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib10","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1053\/j.gastro.2017.06.012","article-title":"Risk of hepatocellular cancer in HCV patients treated with direct-acting antiviral agents","volume":"153","author":"Kanwal","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2023.05.042_bib11","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jhep.2018.03.019","article-title":"Management of hepatocellular carcinoma","volume":"69","year":"2018","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib12","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/hep.29913","article-title":"Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American association for the study of liver diseases","volume":"68","author":"Marrero","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2023.05.042_bib13","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/hepr.13411","article-title":"Clinical practice guidelines for hepatocellular carcinoma: the Japan Society of Hepatology 2017 (4th JSH-HCC guidelines) 2019 update","volume":"49","author":"Kokudo","year":"2019","journal-title":"Hepatol Res"},{"key":"10.1016\/j.jhep.2023.05.042_bib14","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1002\/hep.23691","article-title":"Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection","volume":"52","author":"Asahina","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2023.05.042_bib15","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.cgh.2013.11.033","article-title":"Post-treatment levels of \u03b1-fetoprotein predict incidence of hepatocellular carcinoma after interferon therapy","volume":"12","author":"Oze","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib16","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1053\/j.gastro.2018.07.015","article-title":"Incidence of hepatocellular carcinoma after direct antiviral therapy for HCV in patients with cirrhosis included in surveillance programs","volume":"155","author":"Nahon","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2023.05.042_bib17","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1159\/000513705","article-title":"Impact of obesity and heavy alcohol consumption on hepatocellular carcinoma development after HCV eradication with antivirals","volume":"10","author":"Minami","year":"2021","journal-title":"Liver Cancer"},{"key":"10.1016\/j.jhep.2023.05.042_bib18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1053\/j.gastro.2019.09.009","article-title":"Validation of a machine learning model that outperforms clinical risk scoring systems for upper gastrointestinal bleeding","volume":"158","author":"Shung","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2023.05.042_bib19","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1002\/hep.31103","article-title":"Applying machine learning in liver disease and transplantation: a comprehensive review","volume":"71","author":"Spann","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2023.05.042_bib20","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.2040-1124.2010.00074.x","article-title":"Report of the committee on the classification and diagnostic criteria of diabetes mellitus","volume":"1","author":"Seino","year":"2010","journal-title":"J\u00a0Diabetes Investig"},{"key":"10.1016\/j.jhep.2023.05.042_bib21","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12874-018-0482-1","article-title":"DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network","volume":"18","author":"Katzman","year":"2018","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jhep.2023.05.042_bib22","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/biostatistics\/kxj011","article-title":"Survival ensembles","volume":"7","author":"Hothorn","year":"2006","journal-title":"Biostatistics"},{"key":"10.1016\/j.jhep.2023.05.042_bib23","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1214\/08-AOAS169","article-title":"Random survival forests","volume":"2","author":"Ishwaran","year":"2008","journal-title":"Ann Appl Stat"},{"key":"10.1016\/j.jhep.2023.05.042_bib24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3389\/fnbot.2013.00021","article-title":"Gradient boosting machines, a tutorial","volume":"7","author":"Natekin","year":"2013","journal-title":"Front Neurorobot"},{"key":"10.1016\/j.jhep.2023.05.042_bib25","series-title":"Random forest for bioinformatics","first-page":"307","author":"Qi","year":"2012"},{"key":"10.1016\/j.jhep.2023.05.042_bib26","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1001\/jama.2016.17216","article-title":"Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs","volume":"316","author":"Gulshan","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jhep.2023.05.042_bib27","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1038\/nbt1206-1565","article-title":"What is a support vector machine?","volume":"24","author":"Noble","year":"2006","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jhep.2023.05.042_bib28","first-page":"41","article-title":"Applications of support vector machine (SVM) learning in cancer genomics","volume":"15","author":"Huang","year":"2018","journal-title":"Cancer Genomics Proteomics"},{"key":"10.1016\/j.jhep.2023.05.042_bib29","series-title":"Joint European conference on machine learning and knowledge discovery in databases","first-page":"243","article-title":"Fast training of support vector machines for survival analysis","author":"P\u00f6lsterl","year":"2015"},{"key":"10.1016\/j.jhep.2023.05.042_bib30","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/bioinformatics\/17.6.520","article-title":"Missing value estimation methods for DNA microarrays","volume":"17","author":"Troyanskaya","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jhep.2023.05.042_bib31","unstructured":"Pycox: Open source package for survival analysis and time-to-event prediction. Available at: https:\/\/github.com\/havakv\/pycox."},{"key":"10.1016\/j.jhep.2023.05.042_bib32","first-page":"1","article-title":"Scikit-survival: a library for time-to-event analysis built on top of scikit-learn","volume":"21","author":"P\u00f6lsterl","year":"2020","journal-title":"J\u00a0Machine Learn Res"},{"key":"10.1016\/j.jhep.2023.05.042_bib33","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4","article-title":"Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors","volume":"15","author":"Harrell","year":"1996","journal-title":"Stat Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib34","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.jhep.2020.07.025","article-title":"aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis","volume":"73","author":"Fan","year":"2020","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib35","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/jgh.14378","article-title":"Proposed a simple score for recommendation of scheduled ultrasonography surveillance for hepatocellular carcinoma after Direct Acting Antivirals: multicenter analysis","volume":"34","author":"Hiraoka","year":"2019","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2023.05.042_bib36","first-page":"207","article-title":"Assessing the accuracy of diagnostic tests","volume":"30","author":"Fangyu","year":"2018","journal-title":"Shanghai Arch Psychiatry"},{"key":"10.1016\/j.jhep.2023.05.042_bib37","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1126\/science.3287615","article-title":"Measuring the accuracy of diagnostic systems","volume":"240","author":"Swets","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.jhep.2023.05.042_bib38","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/bioinformatics\/btq134","article-title":"Permutation importance: a corrected feature importance measure","volume":"26","author":"Altmann","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jhep.2023.05.042_bib39","article-title":"A\u00a0unified approach to interpreting model predictions","volume":"30","author":"Lundberg","year":"2017","journal-title":"Adv Neural Inf Process Syst"},{"key":"10.1016\/j.jhep.2023.05.042_bib40","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1056\/NEJMra1814259","article-title":"Machine learning in medicine","volume":"380","author":"Rajkomar","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhep.2023.05.042_bib41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s00198-020-05735-z","article-title":"Comparing three machine learning approaches to design a risk assessment tool for future fractures: predicting a subsequent major osteoporotic fracture in fracture patients with osteopenia and osteoporosis","volume":"32","author":"de Vries","year":"2021","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.jhep.2023.05.042_bib42","first-page":"106","article-title":"Construction the model on the breast cancer survival analysis use support vector machine, logistic regression and decision tree","volume":"38","author":"Chao","year":"2014","journal-title":"J\u00a0Med Syst"},{"key":"10.1016\/j.jhep.2023.05.042_bib43","article-title":"SVM classification in multiclass letter recognition system","volume":"13","author":"Kaushik","year":"2013","journal-title":"Glob J Comput Sci Technol"},{"key":"10.1016\/j.jhep.2023.05.042_bib44","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.3390\/rs12081257","article-title":"A\u00a0new GPU implementation of support vector machines for fast hyperspectral image classification","volume":"12","author":"Paoletti","year":"2020","journal-title":"Remote Sens"},{"key":"10.1016\/j.jhep.2023.05.042_bib45","doi-asserted-by":"crossref","first-page":"5966","DOI":"10.1007\/s11227-019-02894-7","article-title":"Research on SVM environment performance of parallel computing based on large data set of machine learning","volume":"75","author":"Gong","year":"2019","journal-title":"J\u00a0Supercomputing"},{"key":"10.1016\/j.jhep.2023.05.042_bib46","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000252788","article-title":"Dynamic epidemiology of acute viral hepatitis in Japan","volume":"53","author":"Yano","year":"2010","journal-title":"Intervirology"},{"key":"10.1016\/j.jhep.2023.05.042_bib47","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1002\/hep.26442","article-title":"\u03b1-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C","volume":"58","author":"Asahina","year":"2013","journal-title":"Hepatology"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827823004245?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827823004245?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T19:49:30Z","timestamp":1759175370000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827823004245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S0168827823004245"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2023.05.042","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Machine learning for individualized prediction of hepatocellular carcinoma development after the eradication of hepatitis C virus with antivirals","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2023.05.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}