{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:08:17Z","timestamp":1780628897059,"version":"3.54.1"},"reference-count":9,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100552"],"award-info":[{"award-number":["82100552"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004912","name":"Sichuan University","doi-asserted-by":"publisher","award":["ZYGD23031"],"award-info":[{"award-number":["ZYGD23031"]}],"id":[{"id":"10.13039\/501100004912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.jhep.2024.05.005","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T03:13:43Z","timestamp":1715224423000},"page":"e202-e203","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Need for risk stratification in treatment of patients with autoimmune hepatitis"],"prefix":"10.1016","volume":"81","author":[{"given":"Fan","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6548-7089","authenticated-orcid":false,"given":"Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2024.05.005_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhep.2024.03.021","article-title":"Treatment response and clinical event-free survival in autoimmune hepatitis: a Canadian multicentre cohort study","author":"Plagiannakos","year":"2024","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2024.05.005_bib2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s12016-021-08833-w","article-title":"Serum immunoglobulin G levels predict biochemical and histological remission of autoimmune hepatitis type 1: a single-center experience and literature review","volume":"62","author":"Li","year":"2022","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jhep.2024.05.005_bib3","article-title":"Histological activity despite normal ALT and IgG serum levels in patients with autoimmune hepatitis and cirrhosis","volume":"3","author":"Laschtowitz","year":"2021","journal-title":"JHEP Rep"},{"key":"10.1016\/j.jhep.2024.05.005_bib4","article-title":"Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the study of liver diseases","author":"Mack","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2024.05.005_bib5","article-title":"Clinical, biochemical and histological features related to treatment response and prognosis in autoimmune hepatitis","volume":"101497","author":"Guedes","year":"2024","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.jhep.2024.05.005_bib6","first-page":"366","article-title":"Characteristics of initial diagnosis in autoimmune liver disease: an 18-year, retrospective single-center study","volume":"58","author":"Li","year":"2019","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"10.1016\/j.jhep.2024.05.005_bib7","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.jhep.2014.08.010","article-title":"Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance","volume":"61","author":"Albillos","year":"2014","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2024.05.005_bib8","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.cgh.2018.09.046","article-title":"Increased mortality among patients with vs. Without cirrhosis and autoimmune hepatitis","volume":"17","author":"van den Brand","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2024.05.005_bib9","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1111\/apt.15248","article-title":"Beneficial response to mycophenolate mofetil by patients with autoimmune hepatitis who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levels","volume":"49","author":"Nicoll","year":"2019","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827824003386?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827824003386?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:40:08Z","timestamp":1773967208000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827824003386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S0168827824003386"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2024.05.005","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Need for risk stratification in treatment of patients with autoimmune hepatitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2024.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2024.03.021","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 European Association for the Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}