{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:32:49Z","timestamp":1792477969251,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T00:00:00Z","timestamp":1719187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["403224013\/B07"],"award-info":[{"award-number":["403224013\/B07"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["RTG 1715"],"award-info":[{"award-number":["RTG 1715"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB1382"],"award-info":[{"award-number":["SFB1382"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["STE 3003\/1- 1"],"award-info":[{"award-number":["STE 3003\/1- 1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["AI135528"],"award-info":[{"award-number":["AI135528"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["AI119015"],"award-info":[{"award-number":["AI119015"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013457","name":"Center for Sepsis Control and Care","doi-asserted-by":"publisher","award":["FKZ 01EO1502"],"award-info":[{"award-number":["FKZ 01EO1502"]}],"id":[{"id":"10.13039\/501100013457","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jhep.2024.06.019","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T13:45:45Z","timestamp":1719323145000},"page":"971-982","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release upon infection"],"prefix":"10.1016","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2648-8799","authenticated-orcid":false,"given":"Michael","family":"Rooney","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivalee N.","family":"Duduskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8018-7024","authenticated-orcid":false,"given":"Mohamed","family":"Ghait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Rei\u00dfing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Stengel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7696-475X","authenticated-orcid":false,"given":"Philipp A.","family":"Reuken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Quickert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zipprich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1521-3514","authenticated-orcid":false,"given":"Michael","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley J.","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay A.","family":"Rathinam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-5244","authenticated-orcid":false,"given":"Andreas","family":"Stallmach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5576-6914","authenticated-orcid":false,"given":"Tony","family":"Bruns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2024.06.019_bib1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S2468-1253(19)30349-8","article-title":"The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"5","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/s41575-023-00771-6","article-title":"Gut-liver axis: barriers and functional circuits","volume":"20","author":"Pabst","year":"2023","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jhep.2013.07.044","article-title":"Pathological bacterial translocation in liver cirrhosis","volume":"60","author":"Wiest","year":"2014","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib4","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0168-8278(00)00013-1","article-title":"Bacterial translocation of enteric organisms in patients with cirrhosis","volume":"34","author":"Cirera","year":"2001","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib5","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1002\/hep.22564","article-title":"Serum and ascitic fluid bacterial DNA: a new independent prognostic factor in noninfected patients with cirrhosis","volume":"48","author":"Zapater","year":"2008","journal-title":"Hepatol Baltim Md"},{"key":"10.1016\/j.jhep.2024.06.019_bib6","first-page":"1133","article-title":"The prognostic significance of bacterial DNA in patients with decompensated cirrhosis and suspected infection","volume":"36","author":"Bruns","year":"2016","journal-title":"Liver Int Off J Int Assoc Study Liver"},{"key":"10.1016\/j.jhep.2024.06.019_bib7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41575-021-00520-7","article-title":"Cirrhosis-associated immune dysfunction","volume":"19","author":"Albillos","year":"2022","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"Suppl 1","key":"10.1016\/j.jhep.2024.06.019_bib8","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1016\/j.jhep.2020.11.029","article-title":"The multifactorial mechanisms of bacterial infection in decompensated cirrhosis","volume":"75","author":"Van der Merwe","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.693652","article-title":"An epidemiological meta-analysis on the worldwide prevalence, resistance, and outcomes of spontaneous bacterial peritonitis in cirrhosis","volume":"8","author":"Tay","year":"2021","journal-title":"Front Med"},{"key":"10.1016\/j.jhep.2024.06.019_bib10","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/gutjnl-2011-300779","article-title":"Spontaneous bacterial peritonitis: recent guidelines and beyond","volume":"61","author":"Wiest","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2024.06.019_bib11","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.cld.2023.03.013","article-title":"Bacterial infections in acute on chronic liver failure","volume":"27","author":"Incicco","year":"2023","journal-title":"Clin Liver Dis"},{"key":"10.1016\/j.jhep.2024.06.019_bib12","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1111\/j.1365-2036.2012.05076.x","article-title":"Emergence of spontaneous bacterial peritonitis due to enterococci - risk factors and outcome in a 12-year retrospective study","volume":"35","author":"Reuken","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jhep.2024.06.019_bib13","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1053\/jhep.2002.30082","article-title":"Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis","volume":"35","author":"Fern\u00e1ndez","year":"2002","journal-title":"Hepatol Baltim Md"},{"key":"10.1016\/j.jhep.2024.06.019_bib14","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/joim.12054","article-title":"Soluble urokinase plasminogen activator receptor is compartmentally regulated in decompensated cirrhosis and indicates immune activation and short-term mortality","volume":"274","author":"Zimmermann","year":"2013","journal-title":"J Intern Med"},{"key":"10.1016\/j.jhep.2024.06.019_bib15","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1053\/j.gastro.2020.01.029","article-title":"Peritoneal level of CD206 associates with mortality and an inflammatory macrophage phenotype in patients with decompensated cirrhosis and spontaneous bacterial peritonitis","volume":"158","author":"Stengel","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2024.06.019_bib16","article-title":"Immunomodulatory receptor VSIG4 is released during spontaneous bacterial peritonitis and predicts short-term mortality","volume":"4","author":"Rei\u00dfing","year":"2022","journal-title":"JHEP Rep Innov Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/gutjnl-2015-311224","article-title":"Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis","volume":"66","author":"Hackstein","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2024.06.019_bib18","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jhep.2023.02.026","article-title":"Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury","volume":"79","author":"Hackstein","year":"2023","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib19","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.jhep.2016.12.008","article-title":"Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome","volume":"66","author":"Weiss","year":"2017","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/JLB.3MR0821-147R","article-title":"Immunoregulation by type I interferons in the peritoneal cavity","volume":"111","author":"Chuah","year":"2022","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jhep.2024.06.019_bib21","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201948235","article-title":"A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells","volume":"20","author":"Benaoudia","year":"2019","journal-title":"EMBO Rep"},{"key":"10.1016\/j.jhep.2024.06.019_bib22","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aax4917","article-title":"IRF2 transcriptionally induces GSDMD expression for pyroptosis","volume":"12","author":"Kayagaki","year":"2019","journal-title":"Sci Signal"},{"key":"10.1016\/j.jhep.2024.06.019_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.488","article-title":"Revisiting caspases in sepsis","volume":"5","author":"Aziz","year":"2014","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jhep.2024.06.019_bib24","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.4049\/jimmunol.1000803","article-title":"Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia","volume":"185","author":"Lamkanfi","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib25","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1097\/01.CCM.0000155991.88802.4D","article-title":"Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock","volume":"33","author":"Sund\u00e9n-Cullberg","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jhep.2024.06.019_bib26","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/s41590-020-00844-7","article-title":"Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin","volume":"22","author":"Russo","year":"2021","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib27","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis","volume":"69","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib28","doi-asserted-by":"crossref","first-page":"9237","DOI":"10.1073\/pnas.161293498","article-title":"Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition","volume":"98","author":"Bauer","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jhep.2024.06.019_bib29","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aax5135","article-title":"Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis","volume":"12","author":"Casulleras","year":"2020","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jhep.2024.06.019_bib30","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1016\/j.celrep.2014.11.011","article-title":"A distal locus element mediates IFN-\u03b3 priming of lipopolysaccharide-stimulated TNF gene expression","volume":"9","author":"Chow","year":"2014","journal-title":"Cell Rep"},{"key":"10.1016\/j.jhep.2024.06.019_bib31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13100-023-00308-3","article-title":"An intronic LINE-1 regulates IFNAR1 expression in human immune cells","volume":"14","author":"Buttler","year":"2023","journal-title":"Mob DNA"},{"key":"10.1016\/j.jhep.2024.06.019_bib32","doi-asserted-by":"crossref","first-page":"8087","DOI":"10.3390\/ijms21218087","article-title":"Transcriptional regulation of inflammasomes","volume":"21","author":"Cornut","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jhep.2024.06.019_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2022.155911","article-title":"Increased progranulin as an independent predictive biomarker for poor prognosis in sepsis","volume":"155","author":"Shan","year":"2022","journal-title":"Cytokine"},{"key":"10.1016\/j.jhep.2024.06.019_bib34","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s40635-021-00406-7","article-title":"Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study","volume":"9","author":"Brandes","year":"2021","journal-title":"Intensive Care Med Exp"},{"key":"10.1016\/j.jhep.2024.06.019_bib35","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1007\/s10753-014-9911-4","article-title":"Increased serum GP88 (progranulin) concentrations in rheumatoid arthritis","volume":"37","author":"Yamamoto","year":"2014","journal-title":"Inflammation"},{"key":"10.1016\/j.jhep.2024.06.019_bib36","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1038\/ajg.2013.204","article-title":"The 22\/11 risk prediction model: a validated model for predicting 30-day mortality in patients with cirrhosis and spontaneous bacterial peritonitis","volume":"108","author":"Tandon","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhep.2024.06.019_bib37","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13578-015-0007-0","article-title":"Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities","volume":"5","author":"Ren","year":"2015","journal-title":"Cell Biosci"},{"key":"10.1016\/j.jhep.2024.06.019_bib38","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.3389\/fimmu.2018.01135","article-title":"A positive feedback amplifier circuit that regulates interferon (IFN)-Stimulated gene expression and controls type I and type II IFN responses","volume":"9","author":"Michalska","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib39","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.immuni.2019.07.007","article-title":"Differential activation of the transcription factor IRF1 underlies the distinct immune responses elicited by type I and type III interferons","volume":"51","author":"Forero","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.jhep.2024.06.019_bib40","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1136\/gutjnl-2020-321597","article-title":"Primed circulating monocytes are a source of IL-1\u03b2 in patients with cirrhosis and ascites","volume":"70","author":"Stengel","year":"2021","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2024.06.019_bib41","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1136\/gutjnl-2019-320170","article-title":"Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation","volume":"70","author":"Monteiro","year":"2021","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2024.06.019_bib42","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/jid.2010.370","article-title":"Caspase-5 expression is upregulated in lesional psoriatic skin","volume":"131","author":"Salskov-Iversen","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jhep.2024.06.019_bib43","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/s41418-020-00621-x","article-title":"TYK2 licenses non-canonical inflammasome activation during endotoxemia","volume":"28","author":"Poelzl","year":"2021","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jhep.2024.06.019_bib44","doi-asserted-by":"crossref","first-page":"39920","DOI":"10.1074\/jbc.M007255200","article-title":"Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma","volume":"275","author":"Lin","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jhep.2024.06.019_bib45","first-page":"3222","article-title":"Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo","volume":"59","author":"He","year":"1999","journal-title":"Cancer Res"},{"key":"10.1016\/j.jhep.2024.06.019_bib46","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1126\/science.1199214","article-title":"The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice","volume":"332","author":"Tang","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.jhep.2024.06.019_bib47","doi-asserted-by":"crossref","DOI":"10.1172\/JCI144016","article-title":"TNFR2\/14-3-3\u03b5 signaling complex instructs macrophage plasticity in inflammation and autoimmunity","volume":"131","author":"Fu","year":"2021","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jhep.2024.06.019_bib48","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.immuni.2011.01.018","article-title":"Granulin is a soluble cofactor for toll-like receptor 9 signaling","volume":"34","author":"Park","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.jhep.2024.06.019_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00401-018-1861-8","article-title":"The lysosomal function of progranulin, a guardian against neurodegeneration","volume":"136","author":"Paushter","year":"2018","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.jhep.2024.06.019_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0035115","article-title":"Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12)","volume":"7","author":"Suh","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jhep.2024.06.019_bib51","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1111\/imcb.12190","article-title":"Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes","volume":"96","author":"Bitto","year":"2018","journal-title":"Immunol Cel Biol"},{"key":"10.1016\/j.jhep.2024.06.019_bib52","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12946","article-title":"IL-1\u03b1 cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype","volume":"18","author":"Wiggins","year":"2019","journal-title":"Aging Cell"},{"key":"10.1016\/j.jhep.2024.06.019_bib53","first-page":"1878","article-title":"Noncanonical roles of caspase-4 and caspase-5 in heme-driven IL-1\u03b2 release and cell death","volume":"206","author":"Bol\u00edvar","year":"1950","journal-title":"J Immunol Baltim Md"},{"key":"10.1016\/j.jhep.2024.06.019_bib54","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.freeradbiomed.2020.06.017","article-title":"Down regulation of glutathione and glutamate cysteine ligase in the inflammatory response of macrophages","volume":"158","author":"Zhang","year":"2020","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jhep.2024.06.019_bib55","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3389\/fimmu.2018.00268","article-title":"Glutathione S-transferase pi prevents sepsis-related high mobility group box-1 protein translocation and release","volume":"9","author":"Zhou","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib56","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2021108080","article-title":"SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade","volume":"40","author":"Wang","year":"2021","journal-title":"EMBO J"},{"key":"10.1016\/j.jhep.2024.06.019_bib57","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/s41590-020-0697-2","article-title":"Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms","volume":"21","author":"Wandel","year":"2020","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib58","doi-asserted-by":"crossref","first-page":"9701","DOI":"10.3390\/ijms24119701","article-title":"Human GBP1 is involved in the repair of damaged phagosomes\/endolysosomes","volume":"24","author":"Buijze","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jhep.2024.06.019_bib59","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1239474","article-title":"The non-canonical inflammasome activators Caspase-4 and Caspase-5 are differentially regulated during immunosuppression-associated organ damage","volume":"14","author":"Ghait","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.jhep.2024.06.019_bib60","doi-asserted-by":"crossref","first-page":"6543","DOI":"10.2147\/JIR.S339254","article-title":"Progranulin as a potential therapeutic target in immune-mediated diseases","volume":"14","author":"Lan","year":"2021","journal-title":"J Inflamm Res"}],"updated-by":[{"DOI":"10.1016\/j.jhep.2026.05.005","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:00:00Z","timestamp":1781308800000}},{"DOI":"10.1016\/j.jhep.2026.05.005","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000}}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827824023250?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827824023250?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:38:32Z","timestamp":1773967112000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827824023250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":60,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0168827824023250"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2024.06.019","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release upon infection","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2024.06.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver.","name":"copyright","label":"Copyright"}]}}