{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:37:05Z","timestamp":1792175825809,"version":"4.4.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["431667134"],"award-info":[{"award-number":["431667134"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jhep.2025.03.008","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T13:32:33Z","timestamp":1742391153000},"page":"682-691","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effect of albumin treatment duration on response rates and outcomes in patients with cirrhosis and acute kidney injury"],"prefix":"10.1016","volume":"83","author":[{"given":"Eva Maria","family":"Schleicher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5992-7372","authenticated-orcid":false,"given":"Henrik","family":"Karbannek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7344-8381","authenticated-orcid":false,"given":"Julia","family":"Weinmann-Menke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8294-0992","authenticated-orcid":false,"given":"Peter Robert","family":"Galle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-5244","authenticated-orcid":false,"given":"Andreas","family":"Stallmach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3240-5152","authenticated-orcid":false,"given":"Simon Johannes","family":"Gairing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zipprich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9704-4741","authenticated-orcid":false,"given":"Cristina","family":"Ripoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8390-9663","authenticated-orcid":false,"given":"Christian","family":"Labenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jhep.2025.03.008_bib1","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.jhep.2019.07.002","article-title":"News in pathophysiology, definition and classification of hepatorenal syndrome: a step beyond the International Club of Ascites (ICA) consensus document","volume":"71","author":"Angeli","year":"2019","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.jhep.2025.03.008_bib2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/hep.25735","article-title":"Association of AKI with mortality and complications in hospitalized patients with cirrhosis","volume":"57","author":"Belcher","year":"2013","journal-title":"Hepatol Baltim Md"},{"issue":"5","key":"10.1016\/j.jhep.2025.03.008_bib3","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.jhep.2020.04.043","article-title":"Changing epidemiology and outcomes of acute kidney injury in hospitalized patients with cirrhosis \u2013 a US population-based study","volume":"73","author":"Desai","year":"2020","journal-title":"J Hepatol"},{"issue":"1","key":"10.1016\/j.jhep.2025.03.008_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41572-018-0022-7","article-title":"Hepatorenal syndrome","volume":"4","author":"Gin\u00e8s","year":"2018","journal-title":"Nat Rev Dis Primer"},{"issue":"8","key":"10.1016\/j.jhep.2025.03.008_bib5","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1056\/NEJMra2215289","article-title":"Acute kidney injury in patients with cirrhosis","volume":"388","author":"Nadim","year":"2023","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jhep.2025.03.008_bib6","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jhep.2024.03.031","article-title":"Acute kidney injury in patients with Cirrhosis: acute disease quality Initiative (ADQI) and international Club of ascites (ICA) joint multidisciplinary consensus meeting","volume":"81","author":"Nadim","year":"2024","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.jhep.2025.03.008_bib7","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis","volume":"69","year":"2018","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.jhep.2025.03.008_bib8","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1002\/hep.31884","article-title":"Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 practice guidance by the American association for the study of liver diseases","volume":"74","author":"Biggins","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2025.03.008_bib9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s13063-023-07261-9","article-title":"Liver-HERO: hepatorenal syndrome-acute kidney injury (HRS-AKI) treatment with transjugular intrahepatic portosystemic shunt in patients with cirrhosis\u2014a randomized controlled trial","volume":"24","author":"Ripoll","year":"2023","journal-title":"Trials"},{"issue":"4","key":"10.1016\/j.jhep.2025.03.008_bib10","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.jhep.2014.12.029","article-title":"Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites","volume":"62","author":"Angeli","year":"2015","journal-title":"J Hepatol"},{"issue":"3","key":"10.1016\/j.jhep.2025.03.008_bib11","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.jhep.2013.04.036","article-title":"A modified acute kidney injury classification for diagnosis and risk stratification of impairment of kidney function in cirrhosis","volume":"59","author":"Fagundes","year":"2013","journal-title":"J Hepatol"},{"issue":"3","key":"10.1016\/j.jhep.2025.03.008_bib12","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.jhep.2013.03.039","article-title":"Evaluation of the Acute Kidney Injury Network criteria in hospitalized patients with cirrhosis and ascites","volume":"59","author":"Piano","year":"2013","journal-title":"J Hepatol"},{"issue":"3","key":"10.1016\/j.jhep.2025.03.008_bib13","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.cgh.2016.09.156","article-title":"Validation of a staging system for acute kidney injury in patients with cirrhosis and association with acute-on-chronic liver failure","volume":"15","author":"Huelin","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.jhep.2025.03.008_bib14","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jhep.2024.03.006","article-title":"Prospective validation of the EASL management algorithm for acute kidney injury in cirrhosis","volume":"81","author":"Ma","year":"2024","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.jhep.2025.03.008_bib15","doi-asserted-by":"crossref","first-page":"e98","DOI":"10.1016\/j.jhep.2024.07.015","article-title":"Shortening the albumin challenge from 48 to 24 hours may lead to overdiagnosis of hepatorenal syndrome-acute kidney injury and overtreatment with terlipressin","volume":"82","author":"Ma","year":"2025","journal-title":"J Hepatol"},{"issue":"6","key":"10.1016\/j.jhep.2025.03.008_bib16","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1016\/j.jhep.2023.07.010","article-title":"Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US","volume":"79","author":"Patidar","year":"2023","journal-title":"J Hepatol"},{"issue":"7","key":"10.1016\/j.jhep.2025.03.008_bib17","first-page":"1603","article-title":"Fluids in the ICU: which is the right one?","volume":"38","author":"Mayerh\u00f6fer","year":"2023","journal-title":"Nephrol Dial Transpl Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc."},{"issue":"1","key":"10.1016\/j.jhep.2025.03.008_bib18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s00134-014-3538-7","article-title":"Positive fluid balance and AKI diagnosis: assessing the extent and duration of \u2018creatinine dilution\u2019","volume":"41","author":"Prowle","year":"2015","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1016\/j.jhep.2025.03.008_bib19","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1007\/s00134-017-4809-x","article-title":"Renal recovery after acute kidney injury","volume":"43","author":"Forni","year":"2017","journal-title":"Intensive Care Med"},{"issue":"9","key":"10.1016\/j.jhep.2025.03.008_bib20","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1056\/NEJMoa2008290","article-title":"Terlipressin plus albumin for the treatment of type 1 hepatorenal syndrome","volume":"384","author":"Wong","year":"2021","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.jhep.2025.03.008_bib21","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1111\/apt.17195","article-title":"Terlipressin use and respiratory failure in patients with hepatorenal syndrome type 1 and severe acute-on-chronic liver failure","volume":"56","author":"Wong","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"10.1016\/j.jhep.2025.03.008_bib22","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1053\/j.gastro.2023.10.016","article-title":"AGA clinical practice update on the use of vasoactive drugs and intravenous albumin in cirrhosis: expert review","volume":"166","author":"Garcia-Tsao","year":"2024","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1016\/j.jhep.2025.03.008_bib23","doi-asserted-by":"crossref","first-page":"G447","DOI":"10.1152\/ajpgi.00158.2019","article-title":"Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study","volume":"317","author":"Patidar","year":"2019","journal-title":"Am J Physiol - Gastrointest Liver Physiol"},{"issue":"5","key":"10.1016\/j.jhep.2025.03.008_bib24","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000359","article-title":"Urinary NGAL as a diagnostic and prognostic marker for acute kidney injury in cirrhosis: a prospective study","volume":"12","author":"Allegretti","year":"2021","journal-title":"Clin Transl Gastroenterol"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825001643?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825001643?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T12:51:44Z","timestamp":1762260704000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827825001643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0168827825001643"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2025.03.008","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of albumin treatment duration on response rates and outcomes in patients with cirrhosis and acute kidney injury","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2025.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver.","name":"copyright","label":"Copyright"}]}}