{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T13:27:16Z","timestamp":1793366836359,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100012456","name":"Toronto General and Western Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012456","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jhep.2025.04.040","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T19:14:54Z","timestamp":1748459694000},"page":"1116-1127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Personalized survival benefit estimation from living donor liver transplantation with a novel machine learning method for confounding adjustment"],"prefix":"10.1016","volume":"83","author":[{"given":"Anirudh","family":"Gangadhar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-9011","authenticated-orcid":false,"given":"Bima J.","family":"Hasjim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4767-9981","authenticated-orcid":false,"given":"Xun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingji","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Chon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aman","family":"Sidhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Jaeckel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazia","family":"Selzner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Cattral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blayne A.","family":"Sayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Brudno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"McIntosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1960-8449","authenticated-orcid":false,"given":"Mamatha","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2025.04.040_bib1","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1001\/jamasurg.2022.3327","article-title":"Survival benefit of living-donor liver transplant","volume":"157","author":"Jackson","year":"2022","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib2","doi-asserted-by":"crossref","DOI":"10.1097\/HC9.0000000000000219","article-title":"Living donor liver transplantation can address disparities in transplant access for patients with primary sclerosing cholangitis","volume":"7","author":"Onofrio","year":"2023","journal-title":"Hepatol Commun"},{"key":"10.1016\/j.jhep.2025.04.040_bib3","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1097\/SLA.0000000000003463","article-title":"Adult living donor versus deceased donor liver transplant (LDLT versus DDLT) at a single center: time to change our paradigm for liver transplant","volume":"270","author":"Humar","year":"2019","journal-title":"Ann Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib4","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.jhep.2022.07.035","article-title":"Low utilization of adult-to-adult LDLT in Western countries despite excellent outcomes: international multicenter analysis of the US, the UK, and Canada","volume":"77","author":"Ivanics","year":"2022","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2025.04.040_bib5","doi-asserted-by":"crossref","first-page":"52","DOI":"10.21037\/dmr-20-87","article-title":"Expanding living donor liver transplantation in the Western world: changing the paradigm","volume":"3","author":"Tran","year":"2020","journal-title":"Dig Med Res"},{"key":"10.1016\/j.jhep.2025.04.040_bib6","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1001\/jamasurg.2021.3586","article-title":"Sex disparity in liver transplant and access to living donation","volume":"156","author":"Karnam","year":"2021","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/ajt.12907","article-title":"A complete treatment of adult living donor liver transplantation: a review of surgical technique and current challenges to expand indication of patients","volume":"15","author":"Lee","year":"2015","journal-title":"Am J Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib8","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1111\/ajt.16440","article-title":"Meta-analysis and meta-regression of outcomes for adult living donor liver transplantation versus deceased donor liver transplantation","volume":"21","author":"Barbetta","year":"2021","journal-title":"Am J Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib9","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1002\/lt.26386","article-title":"Superior long-term outcomes of adult living donor liver transplantation: a cumulative single-center cohort study with 20 Years of follow-up","volume":"28","author":"Goto","year":"2022","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1467-8519.1995.tb00306.x","article-title":"Community-equipoise and the Ethics of randomized clinical trials","volume":"9","author":"Gifford","year":"1995","journal-title":"Bioethics"},{"key":"10.1016\/j.jhep.2025.04.040_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/jhep.2001.21489","article-title":"Adult living donor liver transplantation: the hepatologist\u2019s perspective","volume":"33","author":"Schiano","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2025.04.040_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1177\/1049732305284011","article-title":"Waiting for a liver transplant","volume":"16","author":"Brown","year":"2006","journal-title":"Qual Health Res"},{"key":"10.1016\/j.jhep.2025.04.040_bib13","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1001\/jama.295.18.2168","article-title":"Integrating palliative care for liver transplant candidates: \u201ctoo well for transplant, too sick for life.\u201d","volume":"295","author":"Larson","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jhep.2025.04.040_bib14","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1093\/ejcts\/ezy167","article-title":"Statistical primer: propensity score matching and its alternatives","volume":"53","author":"Benedetto","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib15","doi-asserted-by":"crossref","first-page":"781","DOI":"10.3982\/ECTA11293","article-title":"Matching on the estimated propensity score","volume":"84","author":"Abadie","year":"2016","journal-title":"Econometrica"},{"key":"10.1016\/j.jhep.2025.04.040_bib16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1017\/pan.2019.11","article-title":"Why propensity scores should not Be used for matching","volume":"27","author":"King","year":"2019","journal-title":"Polit Anal"},{"key":"10.1016\/j.jhep.2025.04.040_bib17","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12874-017-0338-0","article-title":"Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance","volume":"17","author":"Nguyen","year":"2017","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.jhep.2025.04.040_bib18","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1080\/01621459.2000.10474233","article-title":"Combining propensity score matching with additional adjustments for prognostic covariates","volume":"95","author":"Rubin","year":"2000","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.jhep.2025.04.040_bib19","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"335","author":"Elm","year":"2007","journal-title":"BMJ"},{"key":"10.1016\/j.jhep.2025.04.040_bib20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.7326\/M14-0697","article-title":"Transparent reporting of a multivariable prediction model for individual Prognosis or diagnosis (TRIPOD): the TRIPOD statement","volume":"162","author":"Collins","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jhep.2025.04.040_bib21","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1137\/0105003","article-title":"Algorithms for the assignment and transportation problems","volume":"5","author":"Munkres","year":"1957","journal-title":"J Soc Ind Appl Math"},{"key":"10.1016\/j.jhep.2025.04.040_bib22","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1186\/s12859-018-2264-5","article-title":"Random forest versus logistic regression: a large-scale benchmark experiment","volume":"19","author":"Couronn\u00e9","year":"2018","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jhep.2025.04.040_bib23","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1056\/NEJM200006223422507","article-title":"Randomized, controlled trials, observational studies, and the hierarchy of research designs","volume":"342","author":"Concato","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2025.04.040_bib24","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/nrgastro.2017.2","article-title":"Living donor liver transplantation: eliminating the wait for death in end-stage liver disease?","volume":"14","author":"Fisher","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.04.040_bib25","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/SLA.0000000000001383","article-title":"Defining long-term outcomes with living donor liver transplantation in north America","volume":"262","author":"Olthoff","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib26","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1002\/lt.24160","article-title":"Declining liver graft quality threatens the future of liver transplantation in the United States","volume":"21","author":"Orman","year":"2015","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib27","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14954","article-title":"Living donor liver transplant candidate and donor selection and engagement: meeting report from the living donor liver transplant consensus conference","volume":"37","author":"Jesse","year":"2023","journal-title":"Clin Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib28","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1053\/j.gastro.2021.08.050","article-title":"MELD 3.0: the model for end-stage liver disease updated for the modern era","volume":"161","author":"Kim","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2025.04.040_bib29","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.3390\/jcm12082807","article-title":"Living-donor liver transplant and improved post-transplant survival in patients with primary sclerosing cholangitis","volume":"12","author":"Sierra","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.jhep.2025.04.040_bib30","article-title":"Cardiovascular disease in patients with metabolic dysfunction-associated steatohepatitis compared with metabolic dysfunction-associated steatotic liver disease and other liver diseases: a systematic review","volume":"41","author":"Sanyal","year":"2024","journal-title":"Am Heart J Plus Cardiol Res Pract"},{"key":"10.1016\/j.jhep.2025.04.040_bib31","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1111\/ajt.13779","article-title":"Factors associated with major adverse cardiovascular events after liver transplantation among a national sample","volume":"16","author":"VanWagner","year":"2016","journal-title":"Am J Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib32","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ijsu.2020.06.022","article-title":"Living-donor liver transplantation: right versus left","volume":"82","author":"Yagi","year":"2020","journal-title":"Int J Surg"},{"key":"10.1016\/j.jhep.2025.04.040_bib33","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.jhep.2018.12.029","article-title":"Live donor liver transplantation for patients with hepatocellular carcinoma offers increased survival vs. deceased donation","volume":"70","author":"Goldaracena","year":"2019","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2025.04.040_bib34","doi-asserted-by":"crossref","first-page":"S178","DOI":"10.1016\/j.ajt.2023.02.006","article-title":"OPTN\/SRTR 2021 annual data report: liver","volume":"23","author":"Kwong","year":"2023","journal-title":"Am J Transpl"},{"key":"10.1016\/j.jhep.2025.04.040_bib35","doi-asserted-by":"crossref","first-page":"S176","DOI":"10.1016\/j.ajt.2024.01.014","article-title":"OPTN\/SRTR 2022 annual data report: liver","volume":"24","author":"Kwong","year":"2024","journal-title":"Am J Transpl"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825022536?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825022536?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T19:49:04Z","timestamp":1763668144000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827825022536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0168827825022536"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2025.04.040","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Personalized survival benefit estimation from living donor liver transplantation with a novel machine learning method for confounding adjustment","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2025.04.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 European Association for the Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}