{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:58:50Z","timestamp":1790909930402,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002002","name":"Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["1165723N"],"award-info":[{"award-number":["1165723N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["1191522N"],"award-info":[{"award-number":["1191522N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["G032324N"],"award-info":[{"award-number":["G032324N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["1161820N"],"award-info":[{"award-number":["1161820N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","award":["G069321N"],"award-info":[{"award-number":["G069321N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000321","name":"World Cancer Research Fund","doi-asserted-by":"publisher","award":["20-0263"],"award-info":[{"award-number":["20-0263"]}],"id":[{"id":"10.13039\/501100000321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jhep.2025.06.002","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T18:57:22Z","timestamp":1749236242000},"page":"1142-1155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Steatotic liver disease induces YAP\/TAZ-driven cell competition that can suppress tumor initiation"],"prefix":"10.1016","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2209-2447","authenticated-orcid":false,"given":"Ana","family":"Alguer\u00f3-Nadal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1413-1533","authenticated-orcid":false,"given":"Hasse","family":"Mol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0147-3905","authenticated-orcid":false,"given":"Elena","family":"Zoppolato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2037-7644","authenticated-orcid":false,"given":"Weronika","family":"Kowalczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2510-225X","authenticated-orcid":false,"given":"Leticia","family":"Sansores-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4890-8603","authenticated-orcid":false,"given":"Soheil","family":"Soheily","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9036-9925","authenticated-orcid":false,"given":"Hanne","family":"Hillen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leen","family":"van Huffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Van Haele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2503-7171","authenticated-orcid":false,"given":"Marina","family":"Corral-Ib\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1290-8310","authenticated-orcid":false,"given":"Dorothea Katharina","family":"Hoffelner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0990-7034","authenticated-orcid":false,"given":"Leo A.","family":"van Grunsven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2816-1530","authenticated-orcid":false,"given":"Tania","family":"Roskams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4426-6930","authenticated-orcid":false,"given":"Olivier","family":"Govaere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1562-7634","authenticated-orcid":false,"given":"Iv\u00e1n M.","family":"Moya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-3236","authenticated-orcid":false,"given":"Georg","family":"Halder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2025.06.002_bib1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/s41575-019-0145-7","article-title":"From NASH to HCC: current concepts and future challenges","volume":"16","author":"Anstee","year":"2019","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41575-020-00381-6","article-title":"Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention","volume":"18","author":"Huang","year":"2021","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/s41575-023-00754-7","article-title":"Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment","volume":"20","author":"Llovet","year":"2023","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib4","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1002\/hep.24001","article-title":"Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis","volume":"52","author":"Tilg","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2025.06.002_bib5","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.3390\/antiox12091653","article-title":"Oxidative stress in liver pathophysiology and disease","volume":"12","author":"Allameh","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.jhep.2025.06.002_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/9547613","article-title":"Role of oxidative stress in pathophysiology of nonalcoholic fatty liver disease","volume":"2018","author":"Masarone","year":"2018","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.jhep.2025.06.002_bib7","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1016\/j.cell.2023.03.014","article-title":"Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease","volume":"186","author":"Wang","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib8","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/s41586-021-03974-6","article-title":"Convergent somatic mutations in metabolism genes in chronic liver disease","volume":"598","author":"Ng","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jhep.2025.06.002_bib9","doi-asserted-by":"crossref","first-page":"13839","DOI":"10.1073\/pnas.1313192110","article-title":"Hippo pathway effector Yap promotes cardiac regeneration","volume":"110","author":"Xin","year":"2013","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"10.1016\/j.jhep.2025.06.002_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2002278","article-title":"Regulation of insulin-like growth factor signaling by yap governs cardiomyocyte proliferation and embryonic heart size","volume":"4","author":"Xin","year":"2011","journal-title":"Sci Signal"},{"key":"10.1016\/j.jhep.2025.06.002_bib11","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.stem.2017.08.003","article-title":"Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes","volume":"21","author":"K\u00f6hler","year":"2017","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib12","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1126\/science.1065518","article-title":"Negative regulation of neural stem\/progenitor cell proliferation by the Pten tumor suppressor gene in vivo","volume":"294","author":"Groszer","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.jhep.2025.06.002_bib13","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.4049\/jimmunol.174.10.6477","article-title":"Human lymphoid and myeloid cell development in NOD\/LtSz- scid IL2R \u03b3 null mice engrafted with mobilized human hemopoietic stem cells","volume":"174","author":"Shultz","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jhep.2025.06.002_bib14","series-title":"Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant b-Catenin","author":"Tao","year":"2016"},{"key":"10.1016\/j.jhep.2025.06.002_bib15","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/s41586-018-0519-y","article-title":"Necroptosis microenvironment directs lineage commitment in liver cancer","volume":"562","author":"Seehawer","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.jhep.2025.06.002_bib16","doi-asserted-by":"crossref","DOI":"10.1093\/biomethods\/bpaf023","article-title":"Optimized immunofluorescence for liver structure analysis: Enhancing 3D resolution and minimizing tissue autofluorescence","volume":"10","author":"Zoppolato","year":"2025","journal-title":"Biol Methods Protoc"},{"key":"10.1016\/j.jhep.2025.06.002_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121817","article-title":"Modelling fatty liver disease with mouse liver-derived multicellular spheroids","volume":"290","author":"van Os","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.jhep.2025.06.002_bib18","first-page":"378","article-title":"Hippo signaling instructs ectopic but not normal organ growth","author":"Kowalczyk","year":"2022","journal-title":"Science (1979)"},{"key":"10.1016\/j.jhep.2025.06.002_bib19","author":"Moya"},{"key":"10.1016\/j.jhep.2025.06.002_bib20","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/s41591-020-0844-1","article-title":"A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors","volume":"26","author":"Slyper","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.jhep.2025.06.002_bib21","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib22","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cell.2021.12.018","article-title":"Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches","volume":"185","author":"Guilliams","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib23","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/s41684-018-0150-4","article-title":"Model organism data evolving in support of translational medicine","volume":"47","author":"Howe","year":"2018","journal-title":"Lab Anim (NY)"},{"key":"10.1016\/j.jhep.2025.06.002_bib24","doi-asserted-by":"crossref","first-page":"709","DOI":"10.12688\/f1000research.24956.2","article-title":"gprofiler2 \u2013 an R package for gene list functional enrichment analysis and namespace conversion toolset g:Profiler","volume":"9","author":"Kolberg","year":"2020","journal-title":"F1000Res"},{"key":"10.1016\/j.jhep.2025.06.002_bib25","series-title":"Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells. Amsterdam","author":"Ivics","year":"1997"},{"key":"10.1016\/j.jhep.2025.06.002_bib26","doi-asserted-by":"crossref","DOI":"10.1089\/10430349950017734","article-title":"High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA","volume":"10","author":"Zhang","year":"1999","journal-title":"Hum Gene Ther"},{"key":"10.1016\/j.jhep.2025.06.002_bib27","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jhep.2018.03.011","article-title":"A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer","volume":"69","author":"Tsuchida","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib28","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.semcdb.2017.07.004","article-title":"An unexpected friend \u2212 ROS in apoptosis-induced compensatory proliferation: Implications for regeneration and cancer","volume":"80","author":"Diwanji","year":"2018","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib29","series-title":"Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity","author":"Stiles","year":"2003"},{"key":"10.1016\/j.jhep.2025.06.002_bib30","article-title":"Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics","volume":"7","author":"Duan","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jhep.2025.06.002_bib31","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/s41568-023-00579-1","article-title":"Insights into recent findings and clinical application of YAP and TAZ in cancer","volume":"23","author":"Franklin","year":"2023","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jhep.2025.06.002_bib32","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41580-018-0086-y","article-title":"Hippo\u2013YAP\/TAZ signalling in organ regeneration and regenerative medicine","volume":"20","author":"Moya","year":"2019","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib33","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.cmet.2016.09.016","article-title":"Hepatocyte TAZ\/WWTR1 promotes inflammation and fibrosis in nonalcoholic steatohepatitis","volume":"24","author":"Wang","year":"2016","journal-title":"Cell Metab"},{"key":"10.1016\/j.jhep.2025.06.002_bib34","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.jcmgh.2021.06.003","article-title":"Fatty acids activate the transcriptional coactivator YAP1 to promote liver fibrosis via p38 mitogen-activated protein kinase","volume":"12","author":"Salloum","year":"2021","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.ydbio.2021.02.012","article-title":"Cell competition: A historical perspective","volume":"476","author":"Morata","year":"2021","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/0012-1606(75)90330-9","article-title":"Minutes: Mutants of Drosophila autonomously affecting cell division rate","volume":"42","author":"Morata","year":"1975","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib37","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/0023677215571192","article-title":"The carbon tetrachloride model in mice","volume":"49","author":"Scholten","year":"2015","journal-title":"Lab Anim"},{"key":"10.1016\/j.jhep.2025.06.002_bib38","article-title":"Wnt\/\u03b2-catenin signaling in liver development, homeostasis, and pathobiology","author":"Russell","year":"2017","journal-title":"Annu Rev Pathol Mech Dis"},{"key":"10.1016\/j.jhep.2025.06.002_bib39","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/s41568-019-0231-8","article-title":"Outcompeting cancer","volume":"20","author":"Vishwakarma","year":"2020","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jhep.2025.06.002_bib40","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/dgd.12575","article-title":"Cell competition: Emerging mechanisms to eliminate neighbors","volume":"60","author":"Nagata","year":"2018","journal-title":"Dev Growth Differ"},{"key":"10.1016\/j.jhep.2025.06.002_bib41","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/s41576-020-0262-8","article-title":"Emerging mechanisms of cell competition","volume":"21","author":"Baker","year":"2020","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.jhep.2025.06.002_bib42","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/s41580-022-00538-y","article-title":"Cell competition in development, homeostasis and cancer","volume":"24","author":"van Neerven","year":"2023","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib43","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1146\/annurev-cellbio-111315-125142","article-title":"Cell competition: mechanisms and physiological roles","volume":"32","author":"Claver\u00eda","year":"2016","journal-title":"Annu Rev Cell Dev Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib44","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0092-8674(04)00214-4","article-title":"Drosophila Myc regulates organ size by inducing cell competition","author":"De la Cova","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib45","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0092-8674(04)00262-4","article-title":"dMyc transforms cells into super-competitors","volume":"117","author":"Moreno","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib46","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.devcel.2011.06.021","article-title":"Steep differences in wingless signaling trigger Myc-independent competitive cell interactions","volume":"21","author":"Vincent","year":"2011","journal-title":"Dev Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib47","doi-asserted-by":"crossref","DOI":"10.1534\/genetics.106.061929","article-title":"Genes affecting cell competition in drosophila","volume":"175","author":"Tyler","year":"2007","journal-title":"Genetics"},{"key":"10.1016\/j.jhep.2025.06.002_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1001140","article-title":"dMyc functions downstream of yorkie to promote the supercompetitive behavior of hippo pathway mutant cells","volume":"6","author":"Ziosi","year":"2010","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jhep.2025.06.002_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.devcel.2010.09.009","article-title":"Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the drosophila homolog of Yap","volume":"19","author":"Neto-Silva","year":"2010","journal-title":"Dev Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib50","series-title":"The Hippo Signaling Pathway and Cancer","first-page":"307","article-title":"Cell Competition and the Hippo Pathway","author":"Chiao-Lin","year":"2013"},{"key":"10.1016\/j.jhep.2025.06.002_bib51","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.semcdb.2012.06.001","article-title":"Regulation of the Hippo pathway by cell architecture and mechanical signals","volume":"23","author":"Schroeder","year":"2012","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib52","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.devcel.2013.04.013","article-title":"Tissue repair through cell competition and compensatory cellular hypertrophy in postmitotic epithelia","volume":"25","author":"Tamori","year":"2013","journal-title":"Dev Cell"},{"key":"10.1016\/j.jhep.2025.06.002_bib53","article-title":"Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis","volume":"132","author":"Liu","year":"2019","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jhep.2025.06.002_bib54","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1073\/pnas.1113882109","article-title":"Tumor suppression by cell competition through regulation of the Hippo pathway","volume":"109","author":"Chen","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jhep.2025.06.002_bib55","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.cmet.2020.03.010","article-title":"Cholesterol stabilizes TAZ in hepatocytes to promote experimental non-alcoholic steatohepatitis","volume":"31","author":"Wang","year":"2020","journal-title":"Cell Metab"},{"key":"10.1016\/j.jhep.2025.06.002_bib56","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41575-020-00365-6","article-title":"Maladaptive regeneration \u2014 the reawakening of developmental pathways in NASH and fibrosis","volume":"18","author":"Zhu","year":"2021","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2025.06.002_bib57","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s12072-023-10545-6","article-title":"Distinct effects of hepatic steatosis and metabolic dysfunction on the risk of hepatocellular carcinoma in chronic hepatitis B","volume":"17","author":"Huang","year":"2023","journal-title":"Hepatol Int"},{"key":"10.1016\/j.jhep.2025.06.002_bib58","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cmet.2018.10.012","article-title":"Preclinical models for studying NASH-driven HCC: how useful are they?","volume":"29","author":"Febbraio","year":"2019","journal-title":"Cell Metab"},{"key":"10.1016\/j.jhep.2025.06.002_bib59","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/s42003-020-0847-y","article-title":"The COX-2\/PGE2 pathway suppresses apical elimination of RasV12-transformed cells from epithelia","volume":"3","author":"Sato","year":"2020","journal-title":"Commun Biol"},{"key":"10.1016\/j.jhep.2025.06.002_bib60","volume":"vol. 12","author":"Govaere","year":"2020"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825022639?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827825022639?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T19:51:42Z","timestamp":1763668302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827825022639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0168827825022639"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2025.06.002","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Steatotic liver disease induces YAP\/TAZ-driven cell competition that can suppress tumor initiation","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2025.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver.","name":"copyright","label":"Copyright"}]}}