{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:50:08Z","timestamp":1791633008001,"version":"4.3.4"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000765","name":"University College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000765","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jhep.2026.09.007","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:55:01Z","timestamp":1790434501000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reply to: \u201cFrom definitions to phenotyping: A response to the illusion of harmonisation\u201d"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7747-4015","authenticated-orcid":false,"given":"Rajiv","family":"Jalan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4328-0914","authenticated-orcid":false,"given":"Nipun","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2026.09.007_bib1","unstructured":"Artru F, Gustot T, Mahmud N. From definitions to phenotyping: a response to the illusion of harmonisation. J Hepatol (in this issue)."},{"key":"10.1016\/j.jhep.2026.09.007_bib2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jhep.2026.03.039","article-title":"The illusion of harmonisation in ACLF","volume":"85","author":"Jalan","year":"2026","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2026.09.007_bib3","article-title":"A Comparison of Diagnostic Models and prognostic scores of ACLF: towards global Harmonization","author":"Hu","year":"2026","journal-title":"medRxiv"},{"key":"10.1016\/j.jhep.2026.09.007_bib4","first-page":"525","article-title":"Consensus versus Outcome-based definitions of acute-on-chronic liver failure: implications for risk Stratification and case identification","volume":"14","author":"Verma","year":"2026","journal-title":"J Clin Transl Hepatol"},{"key":"10.1016\/j.jhep.2026.09.007_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12072-024-10773-4","article-title":"Acute-on-chronic liver failure (ACLF): the \u2018Kyoto Consensus\u2019-steps from Asia","volume":"19","author":"Choudhury","year":"2025","journal-title":"Hepatol Int"},{"key":"10.1016\/j.jhep.2026.09.007_bib6","article-title":"Harmonising APASL and A-TANGO criteria for acute-on-chronic liver failure: identification of complementary high-risk pre-ACLF populations","author":"Verma","year":"2026","journal-title":"medRxiv"},{"key":"10.1016\/j.jhep.2026.09.007_bib7","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1002\/hep.30494","article-title":"Incidence and mortality of acute-on-chronic liver failure using two definitions in patients with Compensated cirrhosis","volume":"69","author":"Mahmud","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2026.09.007_bib8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jhep.2026.02.017","article-title":"Development and validation of the A-TANGO organ failure score for acute-on-chronic liver failure in global cohorts","volume":"85","author":"Engelmann","year":"2026","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2026.09.007_bib9","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.jhep.2020.06.013","article-title":"The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology","volume":"73","author":"Trebicka","year":"2020","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2026.09.007_bib10","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/s41575-025-01107-2","article-title":"Interaction of inflammation and portal hypertension in cirrhosis progression","volume":"22","author":"Costa","year":"2025","journal-title":"Nat Rev Gastroenterol Hepatol"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827826029004?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827826029004?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:32:42Z","timestamp":1791631962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827826029004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":10,"alternative-id":["S0168827826029004"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2026.09.007","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reply to: \u201cFrom definitions to phenotyping: A response to the illusion of harmonisation\u201d","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2026.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2026.08.009","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2026.03.039","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 European Association for the Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}