{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:25:38Z","timestamp":1767147938990,"version":"build-2238731810"},"update-to":[{"DOI":"10.1016\/j.jhepr.2021.100287","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000}}],"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T00:00:00Z","timestamp":1628726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jhep-reports.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JHEP Reports"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.jhepr.2021.100353","type":"journal-article","created":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T12:38:03Z","timestamp":1630154283000},"page":"100353","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Corrigendum to \u2018Level of MFAP4 in ascites independently predicts 1-year transplant-free survival in patients with cirrhosis\u2019 [JHEP Reports 3 (2021) 100287]"],"prefix":"10.1016","volume":"3","author":[{"given":"Nikolaj","family":"Torp","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mads","family":"Israelsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f8rn","family":"Madsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Lutz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Strassburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Mortensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Wilkens","family":"Knudsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grith Lykke","family":"Sorensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uffe","family":"Holmskov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Schlosser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Thiele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonel","family":"Trebicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksander","family":"Krag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhepr.2021.100353_bib1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/hep.1840070124","article-title":"Compensated cirrhosis: natural history and prognostic factors","volume":"7","author":"Gin\u00e9s","year":"1987","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jhep.2005.10.013","article-title":"Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies","volume":"44","author":"D\u2019Amico","year":"2006","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhepr.2021.100353_bib3","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1056\/NEJMoa0801209","article-title":"Hyponatremia and mortality among patients on the liver-transplant waiting list","volume":"359","author":"Kim","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib4","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/bjs.1800600817","article-title":"Transection of\u00a0the oesophagus for bleeding oesophageal varices","volume":"60","author":"Pugh","year":"1973","journal-title":"Br J Surg"},{"key":"10.1016\/j.jhepr.2021.100353_bib5","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jhep.2014.11.012","article-title":"The CLIF Consortium Acute Decompensation score (CLIF-C ADs) for prognosis of hospitalised cirrhotic patients without acute-on-chronic liver failure","volume":"62","author":"Jalan","year":"2015","journal-title":"J\u00a0Hepatol"},{"issue":"Suppl. 1","key":"10.1016\/j.jhepr.2021.100353_bib6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jhep.2004.11.015","article-title":"Assessment of the prognosis of cirrhosis: Child-Pugh versus MELD","volume":"42","author":"Durand","year":"2005","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhepr.2021.100353_bib7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1001\/archinte.1994.00420020117013","article-title":"Limitations of serum creatinine level and creatinine clearance as filtration markers in cirrhosis","volume":"154","author":"Caregaro","year":"1994","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib8","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/hep.1840400409","article-title":"Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death","volume":"40","author":"Heuman","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib9","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1097\/TP.0000000000002997","article-title":"Patients with persistently low MELD-Na scores continue to be at risk of liver-related death","volume":"104","author":"Mazumder","year":"2020","journal-title":"Transplantation"},{"key":"10.1016\/j.jhepr.2021.100353_bib10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/lt.22218","article-title":"Moderate ascites identifies patients with low model for end-stage liver disease scores awaiting liver transplantation who have a high mortality risk","volume":"17","author":"Somsouk","year":"2011","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2021.100353_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082243","article-title":"Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions","volume":"8","author":"Wulf-Johansson","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.jhepr.2021.100353_bib12","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1074\/jbc.M115.681775","article-title":"Characterization of microfibrillar-associated protein 4 (MFAP4) as a tropoelastin- and fibrillin-binding protein involved in elastic fiber formation","volume":"291","author":"Pilecki","year":"2016","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jhepr.2021.100353_bib13","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1111\/liv.14491","article-title":"Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar-associated protein 4","volume":"40","author":"Madsen","year":"2020","journal-title":"Liver Int"},{"key":"10.1016\/j.jhepr.2021.100353_bib14","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/hep.22764","article-title":"Detection of novel biomarkers of liver cirrhosis by proteomic analysis","volume":"49","author":"M\u00f6lleken","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140418","article-title":"Microfibrillar-associated protein 4: a potential biomarker for screening for liver fibrosis in a mixed patient cohort","volume":"10","author":"S\u00e6kmose","year":"2015","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.jhepr.2021.100353_bib16","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1186\/s12967-016-0952-3","article-title":"Evaluation of the biomarker candidate MFAP4 for non-invasive assessment of hepatic fibrosis in hepatitis C patients","volume":"14","author":"Bracht","year":"2016","journal-title":"J\u00a0Transl Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib17","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1002\/hep.31215","article-title":"Transcriptional dynamics of hepatic sinusoid-associated cells after liver injury","volume":"72","author":"Terkelsen","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib18","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/hep.27368","article-title":"Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up","volume":"61","author":"Ekstedt","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib19","first-page":"170","article-title":"Mortality in biopsy-proven alcohol-related liver disease: a population-based nationwide cohort study of 3453 patients","author":"Hagstr\u00f6m","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.jhepr.2021.100353_bib20","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1136\/gut.2009.203166","article-title":"Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease","volume":"59","author":"Parkes","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.jhepr.2021.100353_bib21","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1002\/hep.1840160318","article-title":"Incidence and predictive factors of first episode of spontaneous bacterial peritonitis in cirrhosis with ascites: relevance of ascitic fluid protein concentration","volume":"16","author":"Llach","year":"1992","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib22","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/0016-5085(93)90284-J","article-title":"Risk factors for spontaneous bacterial peritonitis in cirrhotic patients with ascites","volume":"104","author":"Andreu","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhepr.2021.100353_bib23","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/0016-5085(86)90185-X","article-title":"Low-protein-concentration ascitic fluid is predisposed to spontaneous bacterial peritonitis","volume":"91","author":"Runyon","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhepr.2021.100353_bib24","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2010.06.019","article-title":"Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis","volume":"139","author":"Arvaniti","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhepr.2021.100353_bib25","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1080\/00365521.2017.1411973","article-title":"Low ascitic fluid total protein levels\u00a0is not associated to the development of spontaneous bacterial peritonitis in a cohort of 274 patients with cirrhosis","volume":"53","author":"Mo","year":"2018","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.jhepr.2021.100353_bib26","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jhep.2015.03.040","article-title":"Low ascitic fluid protein does not indicate an increased risk for spontaneous bacterial peritonitis in current cohorts","volume":"63","author":"Bruns","year":"2015","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhepr.2021.100353_bib27","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1111\/liv.12795","article-title":"Risk factors for development of spontaneous bacterial peritonitis and subsequent\u00a0mortality in cirrhotic patients with ascites","volume":"35","author":"Schwabl","year":"2015","journal-title":"Liver Int"},{"key":"10.1016\/j.jhepr.2021.100353_bib28","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1515\/cclm-2015-0284","article-title":"The ratio of calprotectin to total protein as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites","volume":"53","author":"Lutz","year":"2015","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib29","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1097\/MEG.0000000000000217","article-title":"Association of markers of bacterial translocation with immune activation in decompensated cirrhosis","volume":"26","author":"Mortensen","year":"2014","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhepr.2021.100353_bib30","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1515\/cclm-2015-0284","article-title":"The ratio of calprotectin to total protein as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites","volume":"53","author":"Lutz","year":"2015","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib31","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3109\/00365521.2015.1124282","article-title":"Effect of paracentesis on metabolic activity in patients with advanced cirrhosis and ascites","volume":"51","author":"Knudsen","year":"2016","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.jhepr.2021.100353_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082383","article-title":"Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4","volume":"8","author":"S\u00e6kmose","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.jhepr.2021.100353_bib33","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A\u00a0new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jhepr.2021.100353_bib34","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.jhep.2014.02.026","article-title":"Prognostic value of muscle atrophy in cirrhosis using psoas muscle thickness on computed tomography","volume":"60","author":"Durand","year":"2014","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhepr.2021.100353_bib35","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/hep.23478","article-title":"Now there are many (stages) where before there was one: in search of a pathophysiological classification of cirrhosis","volume":"51","author":"Garcia-Tsao","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2021.100353_bib36","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1111\/j.1572-0241.2000.03299.x","article-title":"Ascites fluid as a possible origin for hyperfibrinolysis in advanced liver disease","volume":"95","author":"Agarwal","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhepr.2021.100353_bib37","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1002\/hep.30915","article-title":"Mixed fibrinolytic phenotypes in decompensated cirrhosis and acute-on-chronic liver failure with hypofibrinolysis in those with complications and poor survival","volume":"71","author":"Blasi","year":"2020","journal-title":"Hepatology"}],"container-title":["JHEP Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555921001294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555921001294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:26:45Z","timestamp":1762900005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589555921001294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S2589555921001294"],"URL":"https:\/\/doi.org\/10.1016\/j.jhepr.2021.100353","relation":{},"ISSN":["2589-5559"],"issn-type":[{"value":"2589-5559","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corrigendum to \u2018Level of MFAP4 in ascites independently predicts 1-year transplant-free survival in patients with cirrhosis\u2019 [JHEP Reports 3 (2021) 100287]","name":"articletitle","label":"Article Title"},{"value":"JHEP Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhepr.2021.100353","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jhepr.2021.100287","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL).","name":"copyright","label":"Copyright"}],"article-number":"100353"}}