{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:00:23Z","timestamp":1793289623232,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23DK123408"],"award-info":[{"award-number":["K23DK123408"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jhep-reports.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JHEP Reports"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jhepr.2023.100955","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T09:54:24Z","timestamp":1699005264000},"page":"100955","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Hospital frailty risk score is superior to legacy comorbidity indices for risk adjustment of in-hospital cirrhosis cases"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8731-2370","authenticated-orcid":false,"given":"Archita P.","family":"Desai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swetha","family":"Parvataneni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9017-7007","authenticated-orcid":false,"given":"Shannon M.","family":"Knapp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0837-0746","authenticated-orcid":false,"given":"Lauren D.","family":"Nephew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naga","family":"Chalasani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4784-3246","authenticated-orcid":false,"given":"Marwan S.","family":"Ghabril","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8295-9076","authenticated-orcid":false,"given":"Eric S.","family":"Orman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhepr.2023.100955_bib1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/apt.16806","article-title":"Systematic review: development of a consensus code set to identify cirrhosis in electronic health records","volume":"55","author":"Shearer","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jhepr.2023.100955_bib2","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1007\/s10620-021-07076-1","article-title":"International Classification of Diseases codes are useful in identifying cirrhosis in administrative databases","volume":"67","author":"Dahiya","year":"2022","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jhepr.2023.100955_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9113620","article-title":"The use of administrative data to investigate the population burden of hepatic encephalopathy","volume":"9","author":"Bloom","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.jhepr.2023.100955_bib4","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/hep.31726","article-title":"Administrative coding in electronic health care record-based research of NAFLD: an expert panel consensus statement","volume":"74","author":"Hagstr\u00f6m","year":"2021","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2023.100955_bib5","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1002\/hep.22676","article-title":"Predicting in-hospital mortality in patients with cirrhosis: results differ across risk adjustment methods","volume":"49","author":"Myers","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jhepr.2023.100955_bib6","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S1665-2681(19)31467-X","article-title":"Hospital performance reports based on severity adjusted mortality rates in patients with cirrhosis depend on the method of risk adjustment","volume":"11","author":"Myers","year":"2012","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.jhepr.2023.100955_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","article-title":"Comorbidity measures for use with administrative data","volume":"36","author":"Elixhauser","year":"1998","journal-title":"Med Care"},{"key":"10.1016\/j.jhepr.2023.100955_bib8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.jhepr.2023.100955_bib9","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1053\/j.gastro.2013.09.019","article-title":"Development and validation of a comorbidity scoring system for patients with cirrhosis","volume":"146","author":"Jepsen","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhepr.2023.100955_bib10","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1186\/s12889-015-1733-2","article-title":"The increasing burden and complexity of multimorbidity","volume":"15","author":"Pefoyo","year":"2015","journal-title":"BMC Public Health"},{"key":"10.1016\/j.jhepr.2023.100955_bib11","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1097\/MLR.0b013e31825f64d0","article-title":"Systematic review of comorbidity indices for administrative data","volume":"50","author":"Sharabiani","year":"2012","journal-title":"Med Care"},{"key":"10.1016\/j.jhepr.2023.100955_bib12","doi-asserted-by":"crossref","first-page":"M85","DOI":"10.1093\/geronj\/49.2.M85","article-title":"A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission","volume":"49","author":"Guralnik","year":"1994","journal-title":"J Gerontol"},{"key":"10.1016\/j.jhepr.2023.100955_bib13","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jhepr.2023.100955_bib14","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/hep.32049","article-title":"Malnutrition, frailty, and sarcopenia in patients with cirrhosis: 2021 practice guidance by the American Association for the Study of Liver Diseases","volume":"74","author":"Lai","year":"2021","journal-title":"Hepatology"},{"issue":"Suppl. 1","key":"10.1016\/j.jhepr.2023.100955_bib15","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.1016\/j.jhep.2021.01.025","article-title":"Sarcopenia and frailty in decompensated cirrhosis","volume":"75","author":"Tandon","year":"2021","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhepr.2023.100955_bib16","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/S0140-6736(18)30668-8","article-title":"Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study","volume":"391","author":"Gilbert","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.jhepr.2023.100955_bib17","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/gerona\/glx229","article-title":"Measuring frailty in medicare data: development and validation of a claims-based frailty index","volume":"73","author":"Kim","year":"2018","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jhepr.2023.100955_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/lt.26078","article-title":"Applying administrative data-based coding algorithms for frailty in patients with cirrhosis","author":"Louissaint","year":"2021","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2023.100955_bib19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/lt.25921","article-title":"A\u00a0claims-based frailty risk score is associated with hospitalization for acute-on-chronic liver failure: but is it frailty?","volume":"27","author":"Louissaint","year":"2021","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2023.100955_bib20","article-title":"Frailty is a risk factor for postoperative mortality in patients with cirrhosis undergoing diverse major surgeries","author":"Mahmud","year":"2020","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2023.100955_bib21","first-page":"1","article-title":"Patient frailty is independently associated with the risk of hospitalization for acute-on-chronic liver failure","author":"Shah","year":"2020","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2023.100955_bib22","series-title":"Healthcare Cost and Utilization Project: quality control procedures","year":"2022"},{"key":"10.1016\/j.jhepr.2023.100955_bib23","series-title":"Healthcare Cost and Utilization Project: NIS database documentation","year":"2019"},{"key":"10.1016\/j.jhepr.2023.100955_bib24","doi-asserted-by":"crossref","DOI":"10.14309\/ctg.0000000000000372","article-title":"Contemporary trends in hospitalizations for comorbid chronic liver disease and substance use disorders","volume":"12","author":"Desai","year":"2021","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1016\/j.jhepr.2023.100955_bib25","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.jhep.2020.04.043","article-title":"Changing epidemiology and outcomes of acute kidney injury in hospitalized patients with cirrhosis \u2013 a US population-based study","volume":"73","author":"Desai","year":"2020","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhepr.2023.100955_bib26","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1097\/01.mlr.0000182534.19832.83","article-title":"Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data","volume":"43","author":"Quan","year":"2005","journal-title":"Med Care"},{"key":"10.1016\/j.jhepr.2023.100955_bib27","unstructured":"Healthcare Cost and utilization Project: elixhauser comorbidity software, Version 3.7 Available from:https:\/\/www.hcup-us.ahrq.gov\/toolssoftware\/comorbidity\/comorbidity.jsp. [Accessed 1 May\u00a02019]."},{"key":"10.1016\/j.jhepr.2023.100955_bib28","doi-asserted-by":"crossref","DOI":"10.1214\/ss\/1009213286","article-title":"Interval estimation for a binomial proportion","volume":"16","author":"Brown","year":"2001","journal-title":"Stat Sci"},{"key":"10.1016\/j.jhepr.2023.100955_bib29","series-title":"Binom: binomial confidence intervals for several parameterizations. R package version 1.1-1","author":"Dorai-Raj","year":"2014"},{"key":"10.1016\/j.jhepr.2023.100955_bib30","series-title":"Generalized Additive Models","author":"Wood","year":"2017"},{"key":"10.1016\/j.jhepr.2023.100955_bib31","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1001\/jama.2018.0158","article-title":"The state of US health, 1990\u20132016: burden of diseases, injuries, and risk factors among US states","volume":"319","author":"Mokdad","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.jhepr.2023.100955_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.aohep.2021.100565","article-title":"Extrahepatic causes of death in cirrhosis compared to other chronic conditions in the United States, 1999\u20132017","volume":"26","author":"Shankar","year":"2021","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.jhepr.2023.100955_bib33","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1056\/NEJMra2215289","article-title":"Acute kidney injury in patients with cirrhosis","volume":"388","author":"Nadim","year":"2023","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhepr.2023.100955_bib34","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/cld.1246","article-title":"Falls are an underappreciated driver of morbidity and mortality in cirrhosis","volume":"20","author":"Ha","year":"2022","journal-title":"Clin Liver Dis (Hoboken)"},{"key":"10.1016\/j.jhepr.2023.100955_bib35","article-title":"Confusion assessment method accurately screens for hepatic encephalopathy and predicts short-term mortality in hospitalized patients with cirrhosis","author":"Desai","year":"2022","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.jhepr.2023.100955_bib36","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/lt.26473","article-title":"Neighborhood poverty is associated with failure to be waitlisted and death during liver transplantation evaluation","volume":"28","author":"Mohamed","year":"2022","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhepr.2023.100955_bib37","article-title":"Role of oral health, frailty, and minimal hepatic encephalopathy in the risk of hospitalization: a prospective multi-center cohort of outpatients with cirrhosis","author":"Bajaj","year":"2022","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["JHEP Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555923002860?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555923002860?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T05:59:34Z","timestamp":1716271174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589555923002860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S2589555923002860"],"URL":"https:\/\/doi.org\/10.1016\/j.jhepr.2023.100955","relation":{},"ISSN":["2589-5559"],"issn-type":[{"value":"2589-5559","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hospital frailty risk score is superior to legacy comorbidity indices for risk adjustment of in-hospital cirrhosis cases","name":"articletitle","label":"Article Title"},{"value":"JHEP Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhepr.2023.100955","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL).","name":"copyright","label":"Copyright"}],"article-number":"100955"}}