{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T22:14:53Z","timestamp":1783635293242,"version":"3.55.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3400902"],"award-info":[{"award-number":["2022YFC3400902"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["24141900700"],"award-info":[{"award-number":["24141900700"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82421005"],"award-info":[{"award-number":["82421005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82425038"],"award-info":[{"award-number":["82425038"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82588201"],"award-info":[{"award-number":["82588201"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82203209"],"award-info":[{"award-number":["82203209"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472807"],"award-info":[{"award-number":["82472807"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhep-reports.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JHEP Reports"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jhepr.2026.101789","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:55:25Z","timestamp":1771574125000},"page":"101789","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["ADCY7 dictates N-cadherin stability to inhibit HCC metastasis"],"prefix":"10.1016","volume":"8","author":[{"given":"Jianan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunliang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5702-427X","authenticated-orcid":false,"given":"Youhai","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingye","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyuan","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiru","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhepr.2026.101789_bib1","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.jhepr.2026.101789_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2016.18","article-title":"Hepatocellular carcinoma","volume":"2","author":"Llovet","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jhepr.2026.101789_bib3","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/S0140-6736(22)01200-4","article-title":"Hepatocellular carcinoma","volume":"400","author":"Vogel","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.jhepr.2026.101789_bib4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41575-022-00704-9","article-title":"Evolving therapeutic landscape of advanced hepatocellular carcinoma","volume":"20","author":"Yang","year":"2023","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhepr.2026.101789_bib5","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrgastro.2016.193","article-title":"Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches","volume":"14","author":"Sapisochin","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jhepr.2026.101789_bib6","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s12943-024-02069-w","article-title":"Cancer, metastasis, and the epigenome","volume":"23","author":"Kiri","year":"2024","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jhepr.2026.101789_bib7","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s41591-020-01195-4","article-title":"Targeting metastatic cancer","volume":"27","author":"Ganesh","year":"2021","journal-title":"Nat Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib8","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1158\/0008-5472.CAN-19-0458","article-title":"Defining the hallmarks of metastasis","volume":"79","author":"Welch","year":"2019","journal-title":"Cancer Res"},{"key":"10.1016\/j.jhepr.2026.101789_bib9","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1159\/000512218","article-title":"Epithelial-mesenchymal transition (EMT) as a therapeutic target","volume":"211","author":"Jonckheere","year":"2022","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.jhepr.2026.101789_bib10","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev-pathol-020117-043854","article-title":"Epithelial mesenchymal transition in tumor metastasis","volume":"13","author":"Mittal","year":"2018","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.jhepr.2026.101789_bib11","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3390\/molecules21070965","article-title":"Targeting epithelial-mesenchymal transition (EMT) to overcome drug resistance in cancer","volume":"21","author":"Du","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.jhepr.2026.101789_bib12","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s13045-022-01347-8","article-title":"The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis","volume":"15","author":"Huang","year":"2022","journal-title":"J Hematol Oncol"},{"key":"10.1016\/j.jhepr.2026.101789_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109320","article-title":"Aberrant N-cadherin expression in cancer","volume":"118","author":"Cao","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jhepr.2026.101789_bib14","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/j.1440-1746.2007.05182.x","article-title":"Neural cadherin overexpression is a predictive marker for early postoperative recurrence in hepatocellular carcinoma patients","volume":"23","author":"Seo","year":"2008","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhepr.2026.101789_bib15","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.canlet.2021.08.025","article-title":"ZIP4 promotes non-small cell lung cancer metastasis by activating snail-N-cadherin signaling axis","volume":"521","author":"Jiang","year":"2021","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jhepr.2026.101789_bib16","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1038\/s41388-023-02650-5","article-title":"promotes ovarian cancer metastasis through diminishing ADAM10-dependent N-cadherin cleavage","volume":"42","author":"Chen","year":"2023","journal-title":"Oncogene"},{"key":"10.1016\/j.jhepr.2026.101789_bib17","article-title":"Oxidative stress promotes liver cancer metastasis via RNF25-mediated E-cadherin protein degradation. Adv Sci (Weinheim, Baden-Wurttemberg","volume":"11","author":"Huang","year":"2024","journal-title":"Germany)"},{"key":"10.1016\/j.jhepr.2026.101789_bib18","doi-asserted-by":"crossref","first-page":"6802","DOI":"10.1038\/s41388-020-01471-0","article-title":"Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein","volume":"39","author":"Qian","year":"2020","journal-title":"Oncogene"},{"key":"10.1016\/j.jhepr.2026.101789_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202205873","article-title":"Phosphorylation of USP29 by CDK1 governs TWIST1 stability and oncogenic functions","volume":"10","author":"Guan","year":"2023","journal-title":"Adv Sci"},{"key":"10.1016\/j.jhepr.2026.101789_bib20","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1136\/gutjnl-2024-332902","article-title":"Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC","volume":"74","author":"Chen","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.jhepr.2026.101789_bib21","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41421-022-00445-8","article-title":"Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma","volume":"8","author":"Wang","year":"2022","journal-title":"Cell Discov"},{"key":"10.1016\/j.jhepr.2026.101789_bib22","article-title":"Menyh\u00e1rt O, Nagy \u00c1, Gy\u0151rffy B. Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma","volume":"5","year":"2018","journal-title":"R Soc Open Sci"},{"key":"10.1016\/j.jhepr.2026.101789_bib23","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/s41392-021-00660-x","article-title":"WWP1 targeting MUC1 for ubiquitin-mediated lysosomal degradation to suppress carcinogenesis","volume":"6","author":"Liao","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jhepr.2026.101789_bib24","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2406936121","article-title":"TRIM21 induces selective autophagic degradation of c-Myc and sensitizes regorafenib therapy in colorectal cancer","volume":"121","author":"Ye","year":"2024","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jhepr.2026.101789_bib25","article-title":"GPS-Uber: a hybrid-learning framework for prediction of general and E3-specific lysine ubiquitination sites","volume":"23","author":"Wang","year":"2022","journal-title":"Brief Bioinform"},{"key":"10.1016\/j.jhepr.2026.101789_bib26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/cr.2016.39","article-title":"Ubiquitin modifications","volume":"26","author":"Swatek","year":"2016","journal-title":"Cell Res"},{"key":"10.1016\/j.jhepr.2026.101789_bib27","doi-asserted-by":"crossref","first-page":"4352","DOI":"10.1016\/j.molcel.2023.10.042","article-title":"SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation","volume":"83","author":"Zhang","year":"2023","journal-title":"Mol Cell"},{"key":"10.1016\/j.jhepr.2026.101789_bib28","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1038\/s41418-023-01226-w","article-title":"Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression","volume":"30","author":"Pi","year":"2023","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jhepr.2026.101789_bib29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.semcancer.2022.10.006","article-title":"Mechanisms of cancer metastasis","volume":"87","author":"Castaneda","year":"2022","journal-title":"Semin Cancer Biol"},{"key":"10.1016\/j.jhepr.2026.101789_bib30","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1016\/j.cell.2023.03.003","article-title":"Metastasis","volume":"186","author":"Gerstberger","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.jhepr.2026.101789_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216894","article-title":"Unraveling the tumor microenvironment: insights into cancer metastasis and therapeutic strategies","volume":"591","author":"El-Tanani","year":"2024","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jhepr.2026.101789_bib32","doi-asserted-by":"crossref","first-page":"5235","DOI":"10.1111\/jcmm.14398","article-title":"COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and vimentin","volume":"23","author":"Bhandari","year":"2019","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib33","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1186\/s12967-024-05298-1","article-title":"Elevated SLC1A5 associated with poor prognosis and therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma","volume":"22","author":"Zhang","year":"2024","journal-title":"J Transl Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib34","article-title":"SMYD3 induces sorafenib resistance by activating SMAD2\/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma","volume":"26","author":"Wang","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.jhepr.2026.101789_bib35","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/s41419-024-06908-y","article-title":"MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer","volume":"15","author":"He","year":"2024","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jhepr.2026.101789_bib36","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.apsb.2023.11.008","article-title":"GLUL stabilizes N-cadherin by antagonizing \u03b2-catenin to inhibit the progresses of gastric cancer","volume":"14","author":"Jiang","year":"2024","journal-title":"Acta Pharm Sin B"},{"key":"10.1016\/j.jhepr.2026.101789_bib37","doi-asserted-by":"crossref","first-page":"36818","DOI":"10.1074\/jbc.C000580200","article-title":"Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling","volume":"275","author":"Lin","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jhepr.2026.101789_bib38","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1515\/med-2022-0437","article-title":"Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2","volume":"17","author":"Song","year":"2022","journal-title":"Open Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib39","article-title":"SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts","volume":"8","author":"Xu","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.jhepr.2026.101789_bib40","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.7150\/ijbs.69411","article-title":"The role of ubiquitination and deubiquitination in tumor invasion and metastasis","volume":"18","author":"Han","year":"2022","journal-title":"Int J Biol Sci"},{"key":"10.1016\/j.jhepr.2026.101789_bib41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12943-024-02046-3","article-title":"Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches","volume":"23","author":"Liu","year":"2024","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jhepr.2026.101789_bib42","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.canlet.2021.08.008","article-title":"RNF144A deficiency promotes PD-L1 protein stabilization and carcinogen-induced bladder tumorigenesis","volume":"520","author":"Ho","year":"2021","journal-title":"Cancer Lett"},{"key":"10.1016\/j.jhepr.2026.101789_bib43","article-title":"Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3","volume":"5","author":"Wang","year":"2024","journal-title":"Cell Rep Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib44","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/S1097-2765(00)00134-9","article-title":"Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation","volume":"6","author":"Kavsak","year":"2000","journal-title":"Mol Cell"},{"key":"10.1016\/j.jhepr.2026.101789_bib45","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.tcb.2015.03.002","article-title":"The demographics of the ubiquitin system","volume":"25","author":"Clague","year":"2015","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.jhepr.2026.101789_bib46","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1242\/jcs.183954","article-title":"Ubiquitin chain diversity at a glance","volume":"129","author":"Akutsu","year":"2016","journal-title":"J Cell Sci"},{"key":"10.1016\/j.jhepr.2026.101789_bib47","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1038\/s41418-023-01219-9","article-title":"USP2 promotes tumor immune evasion via deubiquitination and stabilization of PD-L1","volume":"30","author":"Kuang","year":"2023","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jhepr.2026.101789_bib48","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12967-023-03925-x","article-title":"Sirt3 restricts tumor initiation via promoting LONP1 deacetylation and K63 ubiquitination","volume":"21","author":"Wu","year":"2023","journal-title":"J Transl Med"},{"key":"10.1016\/j.jhepr.2026.101789_bib49","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/s41419-025-07599-9","article-title":"RIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination","volume":"16","author":"Lu","year":"2025","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jhepr.2026.101789_bib50","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ccr.2014.05.015","article-title":"Ubiquitylation of autophagy receptor optineurin by HACE1 activates selective autophagy for tumor suppression","volume":"26","author":"Liu","year":"2014","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jhepr.2026.101789_bib51","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/s41392-021-00579-3","article-title":"Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3","volume":"6","author":"Sun","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jhepr.2026.101789_bib52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12943-023-01804-z","article-title":"Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1","volume":"22","author":"Jiang","year":"2023","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jhepr.2026.101789_bib53","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41392-020-0134-x","article-title":"Molecular principles of metastasis: a hallmark of cancer revisited","volume":"5","author":"Fares","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.jhepr.2026.101789_bib54","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1242\/dmm.030403","article-title":"Mouse models of metastasis: progress and prospects","volume":"10","author":"G\u00f3mez-Cuadrado","year":"2017","journal-title":"Dis Model Mech"}],"container-title":["JHEP Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555926000601?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589555926000601?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:25:28Z","timestamp":1783632328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589555926000601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2589555926000601"],"URL":"https:\/\/doi.org\/10.1016\/j.jhepr.2026.101789","relation":{},"ISSN":["2589-5559"],"issn-type":[{"value":"2589-5559","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ADCY7 dictates N-cadherin stability to inhibit HCC metastasis","name":"articletitle","label":"Article Title"},{"value":"JHEP Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhepr.2026.101789","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL).","name":"copyright","label":"Copyright"}],"article-number":"101789"}}