{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:30:06Z","timestamp":1791232206018,"version":"4.1.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofhospitalinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Infection"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.jhin.2015.01.008","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T20:48:25Z","timestamp":1422996505000},"page":"241-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":148,"title":["Multidrug-resistant Gram-negative bacteria: a product of globalization"],"prefix":"10.1016","volume":"89","author":[{"given":"P.M.","family":"Hawkey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhin.2015.01.008_bib1","series-title":"Golden growth restoring the lustre of the European economic model","author":"Gill","year":"2012"},{"key":"10.1016\/j.jhin.2015.01.008_bib2","series-title":"The geography of transport systems","article-title":"The rise of air transportation","author":"Bowen","year":"2013"},{"key":"10.1016\/j.jhin.2015.01.008_bib3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S1473-3099(12)70317-1","article-title":"The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria","volume":"13","author":"Wellington","year":"2013","journal-title":"Lancet Infect Dis"},{"issue":"Suppl. 1","key":"10.1016\/j.jhin.2015.01.008_bib4","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/jac\/dkp256","article-title":"The changing epidemiology of resistance","volume":"64","author":"Hawkey","year":"2009","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib5","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1128\/AAC.46.9.3045-3049.2002","article-title":"Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types","volume":"46","author":"Humeniuk","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib6","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1093\/jac\/29.5.590","article-title":"A\u00a0novel plasmid-mediated extended-spectrum beta-lactamase not derived from TEM- or SHV-type enzymes","volume":"29","author":"Bernard","year":"1992","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib7","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3109\/1040841X.2012.691460","article-title":"Epidemiology and genetics of CTX-M extended-spectrum beta-lactamases in Gram-negative bacteria","volume":"39","author":"Zhao","year":"2013","journal-title":"Crit Rev Microbiol"},{"key":"10.1016\/j.jhin.2015.01.008_bib8","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1093\/jac\/dkl422","article-title":"Occurrence, prevalence and genetic environment of CTX-M \u03b2-lactamases in Enterobacteriaceae from Indian hospitals","volume":"58","author":"Ensor","year":"2006","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib9","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1128\/AAC.46.3.630-637.2002","article-title":"Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China","volume":"46","author":"Chanawong","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib10","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3109\/00365540903493715","article-title":"Extended-spectrum beta-lactamase-producing Escherichia coli in patients with travellers' diarrhoea","volume":"42","author":"Tham","year":"2010","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib11","unstructured":"Census of India 2011: Availability and type of latrine: 2001\u20122011. http:\/\/censusindia.gov.in\/2011census\/hlo\/Data_sheet\/India\/Latrine.pdf [accessed 21.01.15]."},{"key":"10.1016\/j.jhin.2015.01.008_bib12","unstructured":"World Bank. Data: Improved sanitation facilities (% of population with access). http:\/\/data.worldbank.org\/indicator\/SH.STA.ACSN [accessed 21.01.15]."},{"key":"10.1016\/j.jhin.2015.01.008_bib13","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1093\/jac\/dku079","article-title":"Waste water effluent contributes to the dissemination of CTX-M-15 in the natural environment","volume":"69","author":"Amos","year":"2014","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib14","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.ijantimicag.2010.07.002","volume":"36","author":"Hsueh","year":"2010","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jhin.2015.01.008_bib15","doi-asserted-by":"crossref","first-page":"5060","DOI":"10.1128\/AAC.00848-13","article-title":"Characterization of fecal extended-spectrum-beta-lactamase-producing Escherichia coli in a remote community during a long time period","volume":"57","author":"Woerther","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib16","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1139\/W08-059","article-title":"Prevalence of rectal carriage of extended-spectrum beta-lactamase-producing Escherichia coli among elderly people in community settings in China","volume":"54","author":"Tian","year":"2008","journal-title":"Can J Microbiol"},{"key":"10.1016\/j.jhin.2015.01.008_bib17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3109\/00365548.2010.538856","article-title":"High prevalence of CTX-M beta-lactamases in faecal Escherichia coli strains from healthy humans in Fuzhou, China","volume":"43","author":"Li","year":"2011","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib18","doi-asserted-by":"crossref","DOI":"10.1093\/jac\/dkv114","article-title":"Emergence and spread of 016-ST131 and 025b-ST131 clone groups among faecal CTX-M-producing Escherichia coli in healthy individuals in Hunan Province, China","author":"Zhong","year":"2015","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib19","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/jac\/dks018","article-title":"High community faecal carriage rates of CTX-M ESBL-producing Escherichia coli in a specific population group in Birmingham, UK","volume":"67","author":"Wickramasinghe","year":"2012","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib20","doi-asserted-by":"crossref","first-page":"e30498","DOI":"10.1371\/journal.pone.0030498","article-title":"Patient's origin and lifestyle associated with CTX-M-producing Escherichia coli: a case\u2012control\u2012control study","volume":"7","author":"Nicolas-Chanoine","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jhin.2015.01.008_bib21","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1128\/AAC.39.4.824","article-title":"Plasmid-mediated dissemination of the metallo-beta-lactamase gene blaIMP among clinically isolated strains of Serratia marcescens","volume":"39","author":"Ito","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib22","first-page":"53","article-title":"Occurrence of a new metallo-beta-lactamase IMP-4 carried on a conjugative plasmid in Citrobacter youngae from the People's Republic of China","volume":"194","author":"Hawkey","year":"2001","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.jhin.2015.01.008_bib23","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.medmal.2013.11.007","article-title":"Carbapenemase-producing Enterobacteriaceae: overview of a major public health challenge","volume":"44","author":"Nordmann","year":"2014","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.jhin.2015.01.008_bib24","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/AAC.45.3.710-714.2001","article-title":"IMP-4, a novel metallo-\u03b2-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998","volume":"45","author":"Chu","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib25","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1086\/497831","article-title":"Dissemination of the metallo-beta-lactamase gene blaIMP-4 among Gram-negative pathogens in a clinical setting in Australia","volume":"41","author":"Peleg","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib26","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1128\/AAC.01634-07","article-title":"Bla(IMP-4) in different genetic contexts in Enterobacteriaceae isolates from Australia","volume":"52","author":"Espedido","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib27","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1128\/AAC.01099-09","article-title":"Phenotypic and genotypic characterization of Enterobacteriaceae with decreased susceptibility to carbapenems: results from large hospital-based surveillance studies in China","volume":"54","author":"Yang","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib28","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12941-014-0042-4","article-title":"Spread of carbapenemase-producing enterobacteria in a southwest hospital in China","volume":"13","author":"Chen","year":"2014","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"10.1016\/j.jhin.2015.01.008_bib29","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1016\/j.ajic.2014.01.024","article-title":"Fecal carriage of carbapenem-resistant Enterobacteriaceae in a Chinese university hospital","volume":"42","author":"Zhao","year":"2014","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jhin.2015.01.008_bib30","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.tim.2014.09.003","article-title":"Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding","volume":"22","author":"Chen","year":"2014","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.jhin.2015.01.008_bib31","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/cid\/cit795","article-title":"An ongoing national intervention to contain the spread of carbapenem-resistant Enterobacteriaceae","volume":"58","author":"Schwaber","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib32","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S1473-3099(13)70190-7","article-title":"Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases","volume":"13","author":"Munoz-Price","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib33","series-title":"Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals","author":"European Centre for Disease Prevention and Control","year":"2013"},{"key":"10.1016\/j.jhin.2015.01.008_bib34","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/jac\/dkq431","article-title":"ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China","volume":"66","author":"Qi","year":"2011","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib35","doi-asserted-by":"crossref","first-page":"528","DOI":"10.3760\/cma.j.issn.0366-6999.20130253","article-title":"Emergence of Klebsiella pneumoniae carbapenemase-producing Escherichia coli sequence type 131 in Hangzhou, China","volume":"127","author":"Lou","year":"2014","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.jhin.2015.01.008_bib36","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1128\/AAC.00774-09","article-title":"Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India","volume":"53","author":"Yong","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib37","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1473-3099(10)70143-2","article-title":"Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study","volume":"10","author":"Kumarasamy","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib38","doi-asserted-by":"crossref","first-page":"e70406","DOI":"10.1371\/journal.pone.0070406","article-title":"Medical tourism: a cost or benefit to the NHS?","volume":"8","author":"Hanefeld","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jhin.2015.01.008_bib39","doi-asserted-by":"crossref","first-page":"e961","DOI":"10.1016\/j.ijid.2013.04.007","article-title":"Trends in antibiotic susceptibility and incidence of late-onset Klebsiella pneumoniae neonatal sepsis over a six-year period in a neonatal intensive care unit in Karachi, Pakistan","volume":"17","author":"Saleem","year":"2013","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.jhin.2015.01.008_bib40","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.vetmic.2014.02.017","article-title":"Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes","volume":"171","author":"Amos","year":"2014","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.jhin.2015.01.008_bib41","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1128\/AEM.02831-10","article-title":"Fecal carriage and shedding density of CTX-M extended-spectrum \u03b2-lactamase-producing Escherichia coli in cattle, chickens, and pigs: implications for environmental contamination and food production","volume":"77","author":"Horton","year":"2011","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.jhin.2015.01.008_bib42","series-title":"Food outlook","author":"Food and Agriculture Organization of the UN","year":"2011"},{"key":"10.1016\/j.jhin.2015.01.008_bib43","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1126\/science.336.6083.795","article-title":"Public health. China takes aim at rampant antibiotic resistance","volume":"336","author":"Hvistendahl","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jhin.2015.01.008_bib44","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1093\/jac\/dks250","article-title":"Prevalence and characteristics of beta-lactamase and plasmid-mediated quinolone resistance genes in Escherichia coli isolated from farmed fish in China","volume":"67","author":"Jiang","year":"2012","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2015.01.008_bib45","series-title":"Antimicrobial resistance: global report on surveillance","author":"World Health Organization","year":"2014"},{"key":"10.1016\/j.jhin.2015.01.008_bib46","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/jac\/dku333","article-title":"Persistence of Klebsiella pneumoniae ST258 as the predominant clone of carbapenemase-producing Enterobacteriaceae in post-acute-care hospitals in Israel, 2008\u201213","volume":"70","author":"Adler","year":"2015","journal-title":"J\u00a0Antimicrob Chemother"}],"container-title":["Journal of Hospital Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670115000560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670115000560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T20:30:28Z","timestamp":1717705828000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195670115000560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0195670115000560"],"URL":"https:\/\/doi.org\/10.1016\/j.jhin.2015.01.008","relation":{},"ISSN":["0195-6701"],"issn-type":[{"value":"0195-6701","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multidrug-resistant Gram-negative bacteria: a product of globalization","name":"articletitle","label":"Article Title"},{"value":"Journal of Hospital Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhin.2015.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}