{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:08:14Z","timestamp":1792001294404,"version":"4.4.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofhospitalinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Infection"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.jhin.2021.11.020","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T17:44:32Z","timestamp":1638294272000},"page":"120-127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Impact of discontinuing contact precautions and enforcement of basic hygiene measures on nosocomial vancomycin-resistant Enterococcus faecium transmission"],"prefix":"10.1016","volume":"121","author":[{"given":"V.M.","family":"Eichel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Boutin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Frank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Weigand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Heininger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.T.","family":"Mutters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.W.","family":"B\u00fcchler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Heeg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Nurjadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhin.2021.11.020_bib1","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S1473-3099(17)30753-3","article-title":"Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis","volume":"18","author":"Tacconelli","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jhin.2021.11.020_bib2","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.idc.2016.07.009","article-title":"Vancomycin-resistant enterococci: epidemiology, infection prevention, and control","volume":"30","author":"Reyes","year":"2016","journal-title":"Infect Dis Clin N Am"},{"key":"10.1016\/j.jhin.2021.11.020_bib3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1017\/ice.2015.228","article-title":"VRE and VSE bacteremia outcomes in the era of effective VRE therapy: a systematic review and meta-analysis","volume":"37","author":"Prematunge","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhin.2021.11.020_bib4","doi-asserted-by":"crossref","first-page":"100732","DOI":"10.1016\/j.drup.2020.100732","article-title":"Thirty years of VRE in Germany \u2013 \u201cexpect the unexpected\u201d: the view from the National Reference Centre for Staphylococci and Enterococci","volume":"53","author":"Werner","year":"2020","journal-title":"Drug Resist Updat"},{"key":"10.1016\/j.jhin.2021.11.020_bib5","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1093\/jac\/dkaa122","article-title":"Challenges in interpretation of WGS and epidemiological data to investigate nosocomial transmission of vancomycin-resistant Enterococcus faecium in an endemic region: incorporation of patient movement network and admission screening","volume":"75","author":"Eichel","year":"2020","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2021.11.020_bib6","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13756-019-0573-8","article-title":"Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117\/CT71\/vanB -clone in the Rhine-Main metropolitan area of Germany","volume":"8","author":"Falgenhauer","year":"2019","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jhin.2021.11.020_bib7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13756-020-00754-1","article-title":"Increase of vancomycin-resistant Enterococcus faecium strain type ST117 CT71 at Charit\u00e9-Universit\u00e4tsmedizin Berlin, 2008 to 2018","volume":"9","author":"Weber","year":"2020","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jhin.2021.11.020_bib8","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0196-6553(95)90104-3","article-title":"Recommendations for preventing the spread of vancomycin resistance: recommendations of the Hospital Infection Control Practices Advisory Committee (HICPAC)","volume":"23","year":"1995","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jhin.2021.11.020_bib9","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1007\/s00103-018-2811-2","article-title":"Hygienema\u00dfnahmen zur Pr\u00e4vention der Infektion durch Enterokokken mit speziellen Antibiotikaresistenzen","volume":"61","year":"2018","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"key":"10.1016\/j.jhin.2021.11.020_bib10","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1093\/cid\/ciaa009","article-title":"Discontinuing contact precautions for vancomycin-resistant enterococcus (VRE) is associated with rising VRE bloodstream infection rates in Ontario hospitals, 2009\u20132018: a quasi-experimental study","volume":"71","author":"Johnstone","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhin.2021.11.020_bib11","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.ajic.2020.11.020","article-title":"Does the removal of contact precautions for MRSA and VRE infected patients change health care-associated infection rate? A systematic review and meta-analysis","volume":"49","author":"Kleyman","year":"2021","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jhin.2021.11.020_bib12","doi-asserted-by":"crossref","first-page":"780e1","DOI":"10.1016\/j.cmi.2019.10.014","article-title":"Comparative genomic analysis reveals a high prevalence of inter-species in\u00a0vivo transfer of carbapenem-resistance plasmids in patients with haematological malignancies","volume":"26","author":"Kocer","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jhin.2021.11.020_bib13","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1055\/s-0030-1265747","article-title":"Krankenhaushygiene\u2013Das Krankenhaus-Infektions-Surveillance-System (KISS)","volume":"45","author":"Kerwat","year":"2010","journal-title":"Anasthesiol Intensivmed Notfallmed Schmerzther"},{"key":"10.1016\/j.jhin.2021.11.020_bib14","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1128\/JCM.00768-16","article-title":"Development of a real-time PCR protocol requiring minimal handling for detection of vancomycin-resistant enterococci with the fully automated BD Max System","volume":"54","author":"Dalpke","year":"2016","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.jhin.2021.11.020_bib15","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.1128\/JCM.01946-15","article-title":"Core genome multilocus sequence typing scheme for high-resolution typing of Enterococcus faecium","volume":"53","author":"de Been","year":"2015","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.jhin.2021.11.020_bib16","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1093\/nar\/gku1196","article-title":"Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins","volume":"43","author":"Croucher","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jhin.2021.11.020_bib17","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1101\/gr.232397.117","article-title":"GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens","volume":"28","author":"Zhou","year":"2018","journal-title":"Genome Res"},{"key":"10.1016\/j.jhin.2021.11.020_bib18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1017\/ice.2016.235","article-title":"Longitudinal multicenter analysis of outcomes after cessation of control measures for vancomycin-resistant enterococci","volume":"38","author":"Lemieux","year":"2017","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhin.2021.11.020_bib19","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1017\/ice.2015.310","article-title":"Discontinuation of systematic surveillance and contact precautions for vancomycin-resistant enterococcus (VRE) and its impact on the incidence of VRE faecium bacteremia in patients with hematologic malignancies","volume":"37","author":"Almyroudis","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhin.2021.11.020_bib20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13756-020-00754-1","article-title":"Increase of vancomycin-resistant Enterococcus faecium strain type ST117 CT71 at Charite - Universitatsmedizin Berlin, 2008 to 2018","volume":"9","author":"Weber","year":"2020","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jhin.2021.11.020_bib21","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13756-019-0573-8","article-title":"Rhine-Main VSG, et\u00a0al. Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117\/CT71\/vanB clone in the Rhine-Main metropolitan area of Germany","volume":"8","author":"Falgenhauer","year":"2019","journal-title":"Antimicrob Resist Infect Control"},{"issue":"Suppl. 4","key":"10.1016\/j.jhin.2021.11.020_bib22","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ijid.2010.05.002","article-title":"Infection control: the case for horizontal rather than vertical interventional programs","volume":"14","author":"Wenzel","year":"2010","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.jhin.2021.11.020_bib23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jhin.2010.04.027","article-title":"Adverse effects of isolation in hospitalised patients: a systematic review","volume":"76","author":"Abad","year":"2010","journal-title":"J\u00a0Hosp Infect"},{"key":"10.1016\/j.jhin.2021.11.020_bib24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jhin.2017.03.003","article-title":"Corrigendum to \u2018Costs and possible benefits of a two-tier infection control management strategy consisting of active screening for multidrug-resistant organisms and tailored control measures' [Journal of Hospital Infection 93 (2016) 191\u2013196]","volume":"96","author":"Mutters","year":"2017","journal-title":"J\u00a0Hosp Infect"},{"key":"10.1016\/j.jhin.2021.11.020_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jhin.2019.12.007","article-title":"Economic evaluation of vancomycin-resistant enterococci (VRE) control practices: a systematic review","volume":"105","author":"MacDougall","year":"2020","journal-title":"J\u00a0Hosp Infect"}],"container-title":["Journal of Hospital Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670121004291?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670121004291?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T04:20:24Z","timestamp":1759292424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195670121004291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":25,"alternative-id":["S0195670121004291"],"URL":"https:\/\/doi.org\/10.1016\/j.jhin.2021.11.020","relation":{},"ISSN":["0195-6701"],"issn-type":[{"value":"0195-6701","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of discontinuing contact precautions and enforcement of basic hygiene measures on nosocomial vancomycin-resistant Enterococcus faecium transmission","name":"articletitle","label":"Article Title"},{"value":"Journal of Hospital Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhin.2021.11.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society.","name":"copyright","label":"Copyright"}]}}