{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:08:45Z","timestamp":1775664525415,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["304980\/2022\\u20136"],"award-info":[{"award-number":["304980\/2022\\u20136"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2021\/04702\\u20136"],"award-info":[{"award-number":["2021\/04702\\u20136"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2022\/07878\\u20130"],"award-info":[{"award-number":["2022\/07878\\u20130"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofhospitalinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Infection"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.jhin.2025.04.023","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T11:24:18Z","timestamp":1746530658000},"page":"84-94","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Cellular and material-specific responses of Candida parapsilosis biofilms to biocides"],"prefix":"10.1016","volume":"162","author":[{"given":"J.K.S.","family":"Dourado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.M.","family":"\u00c1lvarez-Orme\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Benard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.","family":"Pires","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhin.2025.04.023_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/ffunb.2022.1010782","article-title":"Fluconazole-resistant Candida parapsilosis: a new emerging threat in the fungi arena","volume":"3","author":"Escribano","year":"2022","journal-title":"Front Fungal Biol"},{"key":"10.1016\/j.jhin.2025.04.023_bib2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41579-023-00961-8","article-title":"Candida parapsilosis complex in the clinical setting","volume":"22","author":"Govrins","year":"2024","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib3","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.3389\/fmicb.2018.02997","article-title":"An azole-resistant Candida parapsilosis outbreak: clonal persistence in the intensive care unit of a Brazilian teaching hospital","volume":"9","author":"Thomaz","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib4","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3390\/jof7040259","article-title":"Environmental clonal spread of azole-resistant Candida parapsilosis with Erg11-Y132F mutation causing a large candidemia outbreak in a Brazilian cancer referral center","volume":"7","author":"Thomaz","year":"2021","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.jhin.2025.04.023_bib5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3390\/jof8020100","article-title":"A Brazilian inter-hospital candidemia outbreak caused by fluconazole-resistant Candida parapsilosis in the COVID-19 era","volume":"8","author":"Thomaz","year":"2022","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.jhin.2025.04.023_bib6","article-title":"Prognostic factors of Candida spp. bloodstream infection in adults: a nine-year retrospective cohort study across tertiary hospitals in Brazil and Spain","volume":"6","author":"Agnelli","year":"2021","journal-title":"Lancet Reg Health Am"},{"key":"10.1016\/j.jhin.2025.04.023_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/app.45661","article-title":"Preparation of ibuprofen-loaded HDPE tubular devices for application as urinary catheters","volume":"135","author":"Vieira","year":"2018","journal-title":"J Appl Polym Sci"},{"key":"10.1016\/j.jhin.2025.04.023_bib8","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.3390\/ma14144024","article-title":"Structure and mechanical properties of high-density polyethylene composites reinforced with glassy carbon","volume":"14","author":"Olesik","year":"2021","journal-title":"Materials (Basel)"},{"key":"10.1016\/j.jhin.2025.04.023_bib9","doi-asserted-by":"crossref","first-page":"13182","DOI":"10.1073\/pnas.1201973109","article-title":"Liquid-infused structured surfaces with exceptional anti-biofouling performance","volume":"109","author":"Epstein","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jhin.2025.04.023_bib10","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.actbio.2016.11.070","article-title":"A review of the recent advances in antimicrobial coatings for urinary catheters","volume":"50","author":"Singha","year":"2017","journal-title":"Acta Biomater"},{"key":"10.1016\/j.jhin.2025.04.023_bib11","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/s41522-021-00251-2","article-title":"Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity","volume":"7","author":"Penesyan","year":"2021","journal-title":"NPJ Biofilms Microbiomes"},{"key":"10.1016\/j.jhin.2025.04.023_bib12","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1099\/jmm.0.030932-0","article-title":"Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies","volume":"60","author":"Fauvart","year":"2011","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib13","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1001\/jamasurg.2017.0904","article-title":"Centers for Disease Control and Prevention guideline for the prevention of surgical site infection. 2017","volume":"152","author":"Berr\u00edos-Torres","year":"2017","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jhin.2025.04.023_bib14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.5946\/ce.2013.46.4.337","article-title":"A review of current disinfectants for gastrointestinal endoscopic reprocessing","volume":"46","author":"Park","year":"2013","journal-title":"Clin Endosc"},{"key":"10.1016\/j.jhin.2025.04.023_bib15","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1128\/AAC.01473-07","article-title":"Absence of amphotericin B-tolerant persister cells in biofilms of some Candida species","volume":"52","author":"Al-Dhaheri","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2025.04.023_bib16","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00534-23","article-title":"In vitro activity of sanitizers against mono- and polymicrobial biofilms of C. parapsilosis and S. aureus","volume":"67","author":"Castro","year":"2023","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2025.04.023_bib17","series-title":"Reference method for broth dilution antifungal susceptibility testing of yeasts","year":"2017"},{"key":"10.1016\/j.jhin.2025.04.023_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.598834","article-title":"Oxidative imbalance in Candida tropicalis biofilms and its relation with persister cells","volume":"11","author":"Da Silva","year":"2021","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0181517","article-title":"On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light","volume":"12","author":"Marioni","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jhin.2025.04.023_bib20","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.1128\/AAC.00684-06","article-title":"Candida albicans biofilms produce antifungal-tolerant persister cells","volume":"50","author":"LaFleur","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2025.04.023_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-1-4939-2854-5_6","article-title":"Protocol for determination of the persister subpopulation in Candida albicans biofilms","volume":"1333","author":"De Brucker","year":"2016","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.jhin.2025.04.023_bib22","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/nrmicro.2016.34","article-title":"Distinguishing between resistance, tolerance and persistence to antibiotic treatment","volume":"14","author":"Brauner","year":"2016","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib23","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/apm.12665","article-title":"Central venous catheters and biofilms: where do we stand in 2017?","volume":"125","author":"Gominet","year":"2017","journal-title":"Acta Pathol Microbiol Immunol Scand"},{"key":"10.1016\/j.jhin.2025.04.023_bib24","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1038\/nprot.2008.192","article-title":"In vitro growth and analysis of Candida biofilms","volume":"3","author":"Chandra","year":"2008","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jhin.2025.04.023_bib25","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1038\/s41598-022-07831-y","article-title":"Antibiofilm activity of green synthesized silver nanoparticles against biofilm associated enterococcal urinary pathogens","volume":"12","author":"Swidan","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.jhin.2025.04.023_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.tcsw.2023.100111","article-title":"The role of the Candida biofilm matrix in drug and immune protection","volume":"10","author":"Roy","year":"2023","journal-title":"Cell Surf"},{"key":"10.1016\/j.jhin.2025.04.023_bib27","article-title":"Recent advances in anti-infective catheters for preventing catheters associated urinary tract infections","volume":"499","author":"Liu","year":"2024","journal-title":"Chem Eng J"},{"key":"10.1016\/j.jhin.2025.04.023_bib28","doi-asserted-by":"crossref","first-page":"955","DOI":"10.3390\/jof9100955","article-title":"Biofilm formation in medically important Candida species","volume":"9","author":"Malinovsk\u00e1","year":"2023","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.jhin.2025.04.023_bib29","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/s43856-021-00070-8","article-title":"Ad hoc advisory committee on disinfectants of the Health Council of the Netherlands. Resisting disinfectants","volume":"2","author":"van Dijk","year":"2022","journal-title":"Commun Med"},{"key":"10.1016\/j.jhin.2025.04.023_bib30","doi-asserted-by":"crossref","first-page":"6101","DOI":"10.1128\/AAC.00543-15","article-title":"Delicate metabolic control and coordinated stress response critically determine antifungal tolerance of Candida albicans biofilm persisters","volume":"59","author":"Li","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jhin.2025.04.023_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007301","article-title":"Fungal persister cells: the basis for recalcitrant infections?","volume":"14","author":"Wuyts","year":"2018","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.jhin.2025.04.023_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.03584-20","article-title":"Biofilm development on urinary catheters promotes the appearance of viable but nonculturable bacteria","volume":"12","author":"Wilks","year":"2021","journal-title":"mBio"},{"key":"10.1016\/j.jhin.2025.04.023_bib33","doi-asserted-by":"crossref","DOI":"10.1099\/jmm.0.001377","article-title":"8-hydroxyquinoline-5-(N-4-chlorophenyl) sulfonamide and fluconazole combination as a preventive strategy for Candida biofilm in haemodialysis devices","volume":"70","author":"da Rocha","year":"2021","journal-title":"J Medical Microbiol"},{"key":"10.1016\/j.jhin.2025.04.023_bib34","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1563\/aaid-joi-D-20-00191","article-title":"Filling materials efficacy on preventing biofilm formation inside screw access channels of implant abutments","volume":"48","author":"Ramidan","year":"2022","journal-title":"J Oral Implantol"},{"key":"10.1016\/j.jhin.2025.04.023_bib35","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.3390\/ijms23062983","article-title":"Adhesion of oral bacteria to commercial d-PTFE membranes: polymer microstructure makes a difference","volume":"23","author":"Begi\u0107","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jhin.2025.04.023_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.102333","article-title":"Diverse surface properties reveal that substratum roughness affects fungal spore binding","volume":"24","author":"Whitehead","year":"2021","journal-title":"iScience"},{"key":"10.1016\/j.jhin.2025.04.023_bib37","article-title":"Biomaterials: antimicrobial surfaces in biomedical engineering and healthcare","volume":"22","author":"Sheridan","year":"2022","journal-title":"Curr Opin Biomed Eng"},{"key":"10.1016\/j.jhin.2025.04.023_bib38","article-title":"Efficacy of frontline chemical biocides and disinfection approaches for inactivating SARS-CoV-2 variants of concern that cause coronavirus disease with the emergence of opportunities for green eco-solutions","volume":"23","author":"Rowan","year":"2021","journal-title":"Curr Opin Environ Sci Health"},{"key":"10.1016\/j.jhin.2025.04.023_bib39","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s42977-021-00069-1","article-title":"Biologia Futura: use of biocides during COVID-19-global reshuffling of the microbiota","volume":"72","author":"Paul","year":"2021","journal-title":"Biol Futur"}],"container-title":["Journal of Hospital Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670125001252?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670125001252?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T17:04:34Z","timestamp":1756487074000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195670125001252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":39,"alternative-id":["S0195670125001252"],"URL":"https:\/\/doi.org\/10.1016\/j.jhin.2025.04.023","relation":{},"ISSN":["0195-6701"],"issn-type":[{"value":"0195-6701","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cellular and material-specific responses of Candida parapsilosis biofilms to biocides","name":"articletitle","label":"Article Title"},{"value":"Journal of Hospital Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhin.2025.04.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Healthcare Infection Society. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}