{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:09:09Z","timestamp":1789232949492,"version":"build-2803163510"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:00:00Z","timestamp":1781740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["2599501"],"award-info":[{"award-number":["2599501"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["226691\/Z\/22\/Z"],"award-info":[{"award-number":["226691\/Z\/22\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofhospitalinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hospital Infection"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jhin.2026.06.007","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T06:46:04Z","timestamp":1781851564000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Simulating interventions to prevent gastro-intestinal transmission of Clostridioides difficile and antimicrobial-resistant bacteria in healthcare settings: a model calibration study"],"prefix":"10.1016","volume":"175","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6743-4271","authenticated-orcid":false,"given":"A.","family":"Gerada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Brookfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Howard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Reza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Rosato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.L.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Hope","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhin.2026.06.007_bib1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1017\/ice.2019.282","article-title":"Health outcomes attributable to carbapenemase-producing Enterobacteriaceae infections: a systematic review and meta-analysis","volume":"41","author":"Budhram","year":"2020","journal-title":"Infect Contr Hosp Epidemiol"},{"key":"10.1016\/j.jhin.2026.06.007_bib2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1503\/cmaj.110543","article-title":"The effect of hospital-acquired infection with Clostridium difficile on length of stay in hospital","volume":"184","author":"Forster","year":"2012","journal-title":"CMAJ"},{"key":"10.1016\/j.jhin.2026.06.007_bib3","series-title":"Global report on infection prevention and control","year":"2022"},{"key":"10.1016\/j.jhin.2026.06.007_bib4","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S1473-3099(17)30325-0","article-title":"Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis","volume":"17","author":"Baur","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jhin.2026.06.007_bib5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jhin.2017.07.023","article-title":"A multimodal infection control concept in a burn intensive care unit \u2013 lessons learnt from a meticillin-resistant Staphylococcus Aureus outbreak","volume":"98","author":"Baier","year":"2018","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jhin.2026.06.007_bib6","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/j.ajic.2016.05.014","article-title":"Impact of a prevention bundle on Clostridium Difficile infection rates in a hospital in the Southeastern United States","volume":"44","author":"Davis","year":"2016","journal-title":"Am J Infect Contr"},{"key":"10.1016\/j.jhin.2026.06.007_bib7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.procs.2015.05.267","article-title":"Agent based model and simulation of MRSA transmission in emergency departments","volume":"51","author":"Jaramillo","year":"2015","journal-title":"Proc Comput Sci"},{"key":"10.1016\/j.jhin.2026.06.007_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1009149","article-title":"Covasim: an agent-based model of COVID-19 dynamics and interventions","volume":"17","author":"Kerr","year":"2021","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.jhin.2026.06.007_bib9","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1186\/s12913-019-4627-7","article-title":"Mathematical modelling for health systems research: a systematic review of system dynamics and agent-based models","volume":"19","author":"Cassidy","year":"2019","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.jhin.2026.06.007_bib10","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.ajic.2008.11.010","article-title":"Analysis of an outbreak of Clostridium difficile infection controlled with enhanced infection control measures","volume":"37","author":"Salgado","year":"2009","journal-title":"Am J Infect Contr"},{"key":"10.1016\/j.jhin.2026.06.007_bib11","series-title":"NetLogo. Center for Connected Learning and Computer-Based Modeling","author":"Wilensky","year":"1999"},{"key":"10.1016\/j.jhin.2026.06.007_bib12","series-title":"Engauge digitizer","author":"Mitchell","year":"2020"},{"key":"10.1016\/j.jhin.2026.06.007_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1002803","article-title":"Approximate Bayesian computation","volume":"9","author":"Sunn\u00e5ker","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.jhin.2026.06.007_bib14","series-title":"Health building note 04-01: adult in-patient facilities","year":"2013"},{"key":"10.1016\/j.jhin.2026.06.007_bib15","series-title":"Guidelines for design and construction of health care facilities","year":"2006"},{"key":"10.1016\/j.jhin.2026.06.007_bib16","doi-asserted-by":"crossref","first-page":"e619","DOI":"10.1016\/S2214-109X(18)30186-4","article-title":"Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internet-based global point prevalence survey","volume":"6","author":"Versporten","year":"2018","journal-title":"Lancet Global Health"},{"key":"10.1016\/j.jhin.2026.06.007_bib17","series-title":"HCUP facts and figures: statistics on hospital-based care in the United States in 2005","author":"Levit","year":"2007"},{"key":"10.1016\/j.jhin.2026.06.007_bib18","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00021-17","article-title":"Understanding clostridium difficile colonization","volume":"31","author":"Crobach","year":"2018","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jhin.2026.06.007_bib19","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/jac\/dkt477","article-title":"Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis","volume":"69","author":"Slimings","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jhin.2026.06.007_bib20","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.17597","article-title":"Incidence and outcomes associated with Clostridium Difficile infections: a systematic review and meta-analysis","volume":"3","author":"Marra","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jhin.2026.06.007_bib21","series-title":"Agent-based and individual-based modeling: a practical introduction","year":"2019"},{"key":"10.1016\/j.jhin.2026.06.007_bib22","series-title":"R: a language and environment for statistical computing","year":"2022"},{"key":"10.1016\/j.jhin.2026.06.007_bib23","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1111\/2041-210X.13286","article-title":"The Nlrx r package: a next-generation framework for reproducible NetLogo model analyses","volume":"10","author":"Salecker","year":"2019","journal-title":"Methods Ecol Evol"},{"key":"10.1016\/j.jhin.2026.06.007_bib24","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1177\/0272989X14545788","article-title":"An agent-based simulation model for Clostridium Difficile infection control","volume":"35","author":"Codella","year":"2015","journal-title":"Med Decis Making"},{"key":"10.1016\/j.jhin.2026.06.007_bib25","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1017\/ice.2020.1308","article-title":"An agent-based model to simulate the transmission of vancomycin-resistant enterococci according different prevention and control measures","volume":"42","author":"Deboscker","year":"2021","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhin.2026.06.007_bib26","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1093\/cid\/cix962","article-title":"Interventions to reduce the incidence of hospital-onset clostridium difficile infection: an agent-based modeling approach to evaluate clinical effectiveness in adult acute care hospitals","volume":"66","author":"Barker","year":"2018","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhin.2026.06.007_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0080671","article-title":"A simulation-based assessment of strategies to control clostridium difficile transmission and infection","volume":"8","author":"Rubin","year":"2013","journal-title":"PLOS ONE"},{"key":"10.1016\/j.jhin.2026.06.007_bib28","doi-asserted-by":"crossref","first-page":"2439","DOI":"10.1016\/S0140-6736(24)00862-6","article-title":"Burden of bacterial antimicrobial resistance in low-income and middle-income countries avertible by existing interventions: an evidence review and modelling analysis","volume":"403","author":"Lewnard","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.jhin.2026.06.007_bib29","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.envsoft.2016.09.006","article-title":"Simple or complicated agent-based models? A complicated issue","volume":"86","author":"Sun","year":"2016","journal-title":"Environ Modell Softw"}],"container-title":["Journal of Hospital Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670126002410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195670126002410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:50:07Z","timestamp":1789231807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195670126002410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":29,"alternative-id":["S0195670126002410"],"URL":"https:\/\/doi.org\/10.1016\/j.jhin.2026.06.007","relation":{},"ISSN":["0195-6701"],"issn-type":[{"value":"0195-6701","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simulating interventions to prevent gastro-intestinal transmission of Clostridioides difficile and antimicrobial-resistant bacteria in healthcare settings: a model calibration study","name":"articletitle","label":"Article Title"},{"value":"Journal of Hospital Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhin.2026.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of The Healthcare Infection Society.","name":"copyright","label":"Copyright"}]}}