{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:30:31Z","timestamp":1793788231110,"version":"4.6.1"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltopen.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JHLT Open"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jhlto.2026.100696","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:34:16Z","timestamp":1790004856000},"page":"100696","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Limiting collateral damage: Nosocomial infections in patients with temporary mechanical circulatory support"],"prefix":"10.1016","volume":"14","author":[{"given":"Ryan","family":"Dodge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Bardia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhlto.2026.100696_bib1","article-title":"Outcome and clinical characteristics of nosocomial infection in adult patients undergoing extracorporeal membrane oxygenation: a systematic review and meta-analysis","volume":"10","author":"Li","year":"2022","journal-title":"Front Public Health"},{"key":"10.1016\/j.jhlto.2026.100696_bib2","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.athoracsur.2020.12.012","article-title":"A retrospective study of infection in patients requiring extracorporeal membrane oxygenation support","volume":"112","author":"Quintana","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jhlto.2026.100696_bib3","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1093\/cid\/cis783","article-title":"Nosocomial infections in adult cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation","volume":"55","author":"Schmidt","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhlto.2026.100696_bib4","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1097\/CCM.0000000000002652","article-title":"Nosocomial infections during extracorporeal membrane oxygenation: incidence, etiology, and impact on patients' outcome","volume":"45","author":"Grasselli","year":"2017","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib5","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.healun.2023.07.011","article-title":"Management and outcomes of heart transplant candidates with bloodstream infection on temporary mechanical circulatory support","volume":"42","author":"Eichenberger","year":"2023","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.recesp.2020.11.011","article-title":"Infectious complications associated with short-term mechanical circulatory support in urgent heart transplant candidates","volume":"75","author":"Solla-Buceta","year":"2022","journal-title":"Rev Esp Cardiol (Engl Ed)."},{"key":"10.1016\/j.jhlto.2026.100696_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s13613-019-0490-2","article-title":"Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation","volume":"9","author":"Pons","year":"2019","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.jhlto.2026.100696_bib8","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.123.030819","article-title":"Complications and outcomes of impella treatment in cardiogenic shock patients with and without acute myocardial infarction","volume":"12","author":"Saito","year":"2023","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jhlto.2026.100696_bib9","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/MAT.0000000000000877","article-title":"Clinical outcomes of impella microaxial devices used to salvage cardiogenic shock as a bridge to durable circulatory support or cardiac transplantation","volume":"65","author":"Cheng","year":"2019","journal-title":"ASAIO J"},{"key":"10.1016\/j.jhlto.2026.100696_bib10","doi-asserted-by":"crossref","first-page":"e373","DOI":"10.1016\/j.athoracsur.2020.09.069","article-title":"Impella 5.5 direct aortic implant and explant techniques","volume":"111","author":"Anderson","year":"2021","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jhlto.2026.100696_bib11","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.hrtlng.2019.01.004","article-title":"Epidemiology of blood stream infection in adult extracorporeal membrane oxygenation patients: a cohort study","volume":"48","author":"Menaker","year":"2019","journal-title":"Heart Lung"},{"key":"10.1016\/j.jhlto.2026.100696_bib12","article-title":"Clinical and microbiological characteristics of and risk factors for bloodstream infections among patients with extracorporeal membrane oxygenation: a single-center retrospective cohort study","volume":"12","author":"Lee","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.jhlto.2026.100696_bib13","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.healun.2024.03.004","article-title":"The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices","volume":"43","author":"Aslam","year":"2024","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib14","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.healun.2019.01.007","article-title":"Epidemiology of infection in mechanical circulatory support: a global analysis from the ISHLT Mechanically Assisted Circulatory Support Registry","volume":"38","author":"Hannan","year":"2019","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib15","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.healun.2024.12.019","article-title":"Impact of complications on survival outcomes in different temporary mechanical circulatory support techniques: a large retrospective cohort study of cardiac surgical and nonsurgical patients","volume":"44","author":"Ott","year":"2025","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib16","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1186\/s13054-024-04946-8","article-title":"Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis","volume":"28","author":"Ait Hssain","year":"2024","journal-title":"Crit Care"},{"key":"10.1016\/j.jhlto.2026.100696_bib17","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.2147\/IDR.S390599","article-title":"Impact of nosocomial infection on in-Hospital mortality rate in adult patients under venoarterial extracorporeal membrane oxygenation after cardiac surgery","volume":"16","author":"Li","year":"2023","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jhlto.2026.100696_bib18","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S2213-2600(22)00438-6","article-title":"Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES): an international, multicentre, retrospective cohort study","volume":"11","author":"Schmidt","year":"2023","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib19","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s00134-020-06331-9","article-title":"Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19","volume":"47","author":"Shaefi","year":"2021","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib20","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/MAT.0000000000000771","article-title":"Cannula-related infection in patients supported by peripheral ECMO: clinical and microbiological characteristics","volume":"65","author":"Allou","year":"2019","journal-title":"ASAIO J"},{"key":"10.1016\/j.jhlto.2026.100696_bib21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jhin.2024.10.011","article-title":"Nosocomial infection in paediatric patients undergoing extracorporeal membrane oxygenation: a systematic review and meta-analysis","volume":"155","author":"Li","year":"2025","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jhlto.2026.100696_bib22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12887-023-03908-3","article-title":"First nosocomial infections in children supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO)","volume":"23","author":"Cousin","year":"2023","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.jhlto.2026.100696_bib23","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.healun.2022.12.018","article-title":"Complications related to the access site after transaxillary implantation of a microaxial left ventricular assist device","volume":"42","author":"Lewin","year":"2023","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib24","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1161\/CIR.0000000000001076","article-title":"Escalating and de-escalating temporary mechanical circulatory support in cardiogenic shock: a scientific statement from the American Heart Association","volume":"146","author":"Geller","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.jhlto.2026.100696_bib25","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.healun.2011.01.717","article-title":"Working formulation for the standardization of definitions of infections in patients using ventricular assist devices","volume":"30","author":"Hannan","year":"2011","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib26","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.healun.2020.03.010","article-title":"Updated definitions of adverse events for trials and registries of mechanical circulatory support: a consensus statement of the mechanical circulatory support academic research consortium","volume":"39","author":"Kormos","year":"2020","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.jhlto.2026.100696_bib27","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.cardfail.2019.01.012","article-title":"HFSA\/SAEM\/ISHLT clinical expert consensus document on the emergency management of patients with ventricular assist devices","volume":"25","author":"Givertz","year":"2019","journal-title":"J Card Fail"},{"key":"10.1016\/j.jhlto.2026.100696_bib28","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.transproceed.2017.02.064","article-title":"Extracorporeal life support as a bridge to lung transplantation in patients with acute respiratory failure","volume":"49","author":"Yeo","year":"2017","journal-title":"Transpl Proc"},{"key":"10.1016\/j.jhlto.2026.100696_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0257449","article-title":"Biofilm microbiome in extracorporeal membrane oxygenator catheters","volume":"16","author":"Yu","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.jhlto.2026.100696_bib30","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/cid\/ciae120","article-title":"Nosocomial infections in adults receiving extracorporeal membrane oxygenation: a review for infectious diseases clinicians","volume":"79","author":"Marcus","year":"2024","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhlto.2026.100696_bib31","article-title":"Infection in ECMO patients: changes in epidemiology, diagnosis and prevention","volume":"43","author":"Pe\u00f1a-L\u00f3pez","year":"2024","journal-title":"Anaesth Crit Care Pain Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib32","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1017\/ice.2022.88","article-title":"Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update","volume":"43","author":"Klompas","year":"2022","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhlto.2026.100696_bib33","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1164\/rccm.201610-2075ST","article-title":"An Official American Thoracic Society\/American College of chest physicians clinical practice guideline: liberation from mechanical ventilation in critically Ill adults. Rehabilitation protocols, ventilator liberation protocols, and cuff leak tests","volume":"195","author":"Girard","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib34","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1001\/jamaoto.2021.0025","article-title":"Association of early vs late tracheostomy placement with pneumonia and ventilator days in critically Ill patients: a meta-analysis","volume":"147","author":"Chorath","year":"2021","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.jhlto.2026.100696_bib35","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1097\/CCM.0000000000004382","article-title":"Effects of rehabilitation interventions on clinical outcomes in critically Ill patients: systematic review and meta-analysis of randomized controlled trials","volume":"48","author":"Waldauf","year":"2020","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib36","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/CCM.0000000000002770","article-title":"Safety and feasibility of early physical therapy for patients on extracorporeal membrane oxygenator: University of Maryland Medical Center Experience","volume":"46","author":"Wells","year":"2018","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib37","doi-asserted-by":"crossref","DOI":"10.1186\/s13613-020-00776-3","article-title":"Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study","volume":"10","author":"Braune","year":"2020","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.jhlto.2026.100696_bib38","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1017\/ice.2022.87","article-title":"Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update","volume":"43","author":"Buetti","year":"2022","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhlto.2026.100696_bib39","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1016\/S0140-6736(15)00244-5","article-title":"Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial","volume":"386","author":"Mimoz","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.jhlto.2026.100696_bib40","doi-asserted-by":"crossref","DOI":"10.1186\/s13613-018-0416-4","article-title":"Effectiveness of antimicrobial-coated central venous catheters for preventing catheter-related blood-stream infections with the implementation of bundles: a systematic review and network meta-analysis","volume":"8","author":"Wang","year":"2018","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.jhlto.2026.100696_bib41","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1017\/ice.2023.137","article-title":"Strategies to prevent catheter-associated urinary tract infections in acute-care hospitals: 2022 update","volume":"44","author":"Patel","year":"2023","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhlto.2026.100696_bib42","article-title":"Infection Control and Extracorporeal Life Support","author":"Hines","year":"2025","journal-title":"Extracorporeal Life Support Organization"},{"key":"10.1016\/j.jhlto.2026.100696_bib43","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1513\/AnnalsATS.202008-974OC","article-title":"Efficacy of prophylactic antibiotics during extracorporeal membrane oxygenation: a nationwide cohort study","volume":"18","author":"Kondo","year":"2021","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jhlto.2026.100696_bib44","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/MAT.0000000000000287","article-title":"The evidence base for prophylactic antibiotics in patients receiving extracorporeal membrane oxygenation","volume":"62","author":"O'Horo","year":"2016","journal-title":"ASAIO J"},{"key":"10.1016\/j.jhlto.2026.100696_bib45","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13054-017-1644-y","article-title":"Medicating patients during extracorporeal membrane oxygenation: the evidence is building","volume":"21","author":"Dzierba","year":"2017","journal-title":"Crit Care"},{"key":"10.1016\/j.jhlto.2026.100696_bib46","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1164\/rccm.202207-1393OC","article-title":"Antimicrobial exposures in critically Ill patients receiving extracorporeal membrane oxygenation","volume":"207","author":"Shekar","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib47","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s00134-019-05847-z","article-title":"ECLS-associated infections in adults: what we know and what we don't yet know","volume":"46","author":"Abrams","year":"2020","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jhlto.2026.100696_bib48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1086\/668439","article-title":"Infections acquired by adults who receive extracorporeal membrane oxygenation: risk factors and outcome","volume":"34","author":"Aubron","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jhlto.2026.100696_bib49","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1097\/MAT.0000000000001679","article-title":"Use of impella in patients listed for heart transplantation","volume":"68","author":"Pahwa","year":"2022","journal-title":"ASAIO J"},{"key":"10.1016\/j.jhlto.2026.100696_bib50","doi-asserted-by":"crossref","first-page":"5075","DOI":"10.21037\/jtd.2017.10.142","article-title":"Outcomes of perioperative extracorporeal membrane oxygenation use in patients undergoing lung transplantation","volume":"9","author":"Song","year":"2017","journal-title":"J Thorac Dis"}],"container-title":["JHLT Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S295013342600217X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S295013342600217X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:15:46Z","timestamp":1793787346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S295013342600217X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":50,"alternative-id":["S295013342600217X"],"URL":"https:\/\/doi.org\/10.1016\/j.jhlto.2026.100696","relation":{},"ISSN":["2950-1334"],"issn-type":[{"value":"2950-1334","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Limiting collateral damage: Nosocomial infections in patients with temporary mechanical circulatory support","name":"articletitle","label":"Article Title"},{"value":"JHLT Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhlto.2026.100696","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.","name":"copyright","label":"Copyright"}],"article-number":"100696"}}