{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:07:11Z","timestamp":1791976031026,"version":"4.4.0"},"reference-count":68,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Hand Surgery"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.jhsa.2009.06.013","type":"journal-article","created":{"date-parts":[[2009,8,23]],"date-time":"2009-08-23T08:34:48Z","timestamp":1251016488000},"page":"1340-1350","source":"Crossref","is-referenced-by-count":65,"title":["Embryology of the Upper Limb"],"prefix":"10.1016","volume":"34","author":[{"given":"Mohammad M.","family":"Al-Qattan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingzi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott H.","family":"Kozin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhsa.2009.06.013_bib1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1086\/377110","article-title":"Genetic disorders of the skeleton: a developmental approach","volume":"73","author":"Kornak","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib2","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0092-8674(00)80364-5","article-title":"Molecular models for vertebrate limb development","volume":"90","author":"Johnson","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib3","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1242\/dev.023176","article-title":"Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development","volume":"135","author":"ten Berge","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib4","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1101\/gad.1017802","article-title":"The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6","volume":"16","author":"Akiyana","year":"2002","journal-title":"Genes Dev"},{"key":"10.1016\/j.jhsa.2009.06.013_bib5","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1242\/dev.127.14.3141","article-title":"Dual roles of Wnt signaling during chondrogenesis in the chicken limb","volume":"127","author":"Hartmann","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib6","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/dvdy.10046","article-title":"Frizzled-7 and limb mesenchymal chondrogenesis: effect of misexpression and involvement on N-cadherin","volume":"223","author":"Tufan","year":"2002","journal-title":"Dev Dyn"},{"key":"10.1016\/j.jhsa.2009.06.013_bib7","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/jcb.20190","article-title":"Long-term in vitro analysis of limb cartilage development: involvement of Wnt signaling","volume":"93","author":"Daumer","year":"2004","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.jhsa.2009.06.013_bib8","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00418-005-0756-7","article-title":"Comparative analysis of the expression patterns of Wnts during chick limb development","volume":"123","author":"Logunathan","year":"2005","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0092-8674(01)00222-7","article-title":"Wnt14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton","volume":"104","author":"Hartmann","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib10","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0749-0712(21)01370-6","article-title":"Upper limb tissue differentiation in the human embryo","volume":"1","author":"Beatty","year":"1985","journal-title":"Hand Clin"},{"key":"10.1016\/j.jhsa.2009.06.013_bib11","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0749-0712(21)01369-X","article-title":"Development of the upper limb","volume":"1","author":"Zaleske","year":"1985","journal-title":"Hand Clin"},{"key":"10.1016\/j.jhsa.2009.06.013_bib12","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/(SICI)1097-4687(199609)229:3<337::AID-JMOR8>3.0.CO;2-V","article-title":"Sequential changes of programmed cell death in developing fetal mouse limbs and its possible roles in limb morphogenesis","volume":"229","author":"Kimura","year":"1996","journal-title":"J Morphol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1053\/jhsu.2001.9419","article-title":"The molecular control of upper extremity development: implications for congenital hand anomalies","volume":"26A","author":"Daluiski","year":"2001","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1006\/dbio.1997.8576","article-title":"Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway","volume":"186","author":"Marazzi","year":"1997","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0092-8674(91)90612-3","article-title":"Retinoids, homeoboxes, and growth factors: toward molecular models for limb development","volume":"66","author":"Tabin","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib16","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/383407a0","article-title":"Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function","volume":"383","author":"Chiang","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib17","first-page":"558","article-title":"Homozygous Wnt3 mutation causes tetra-amelia in a large consanguineous family","volume":"74","author":"Niemann","year":"2004","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib18","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ydbio.2007.03.014","article-title":"Wnt\/\u03b2-catenin signaling has an essential role in the initiation of limb regeneration","volume":"306","author":"Yokoyma","year":"2007","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib19","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/19539","article-title":"p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development","volume":"398","author":"Yang","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib20","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1101\/gad.1686208","article-title":"Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice","volume":"22","author":"Grigoryan","year":"2008","journal-title":"Genes Dev"},{"key":"10.1016\/j.jhsa.2009.06.013_bib21","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/01.PRS.0000146703.08958.95","article-title":"Understanding the molecular basis of Apert syndrome","volume":"115","author":"Ibrahimi","year":"2005","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/ng0396-315","article-title":"A human chondrodysplasia due to a mutation in a TGF-beta superfamily member","volume":"12","author":"Thomas","year":"1996","journal-title":"Nat Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib23","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/ng0997-58","article-title":"Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1","volume":"17","author":"Thomas","year":"1997","journal-title":"Nat Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib24","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1054\/bjps.2000.3505","article-title":"Classification of hand anomalies in Poland's syndrome","volume":"54","author":"Al-Qattan","year":"2001","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib25","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/01.sap.0000143863.52037.dc","article-title":"The middle phalanx in Poland syndrome","volume":"54","author":"Al-Qattan","year":"2005","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib26","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0266-7681(91)90014-F","article-title":"Arteriographic findings in radial and ulnar deficiencies","volume":"16B","author":"Inoue","year":"1991","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib27","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0266-7681(90)90121-J","article-title":"Congenital malformations of the hand","volume":"15B","author":"Hadidi","year":"1990","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib28","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1177\/1753193408089572","article-title":"The bifid median nerve re-visited","volume":"34E","author":"Al-Qattan","year":"2009","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib29","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00003086-199602000-00003","article-title":"Congenital anomalies of the hand","volume":"323","author":"Ogino","year":"1996","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.jhsa.2009.06.013_bib30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0266-7681(05)80029-4","article-title":"Congenital varicella of the upper limb","volume":"20B","author":"Al-Qattan","year":"1995","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib31","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1097\/00000637-200044060-00008","article-title":"Classification of the pattern of intrauterine amputations of the upper limb in constriction ring syndrome","volume":"44","author":"Al-Qattan","year":"2000","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib32","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/jez.1401080304","article-title":"The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm","volume":"108","author":"Saunders","year":"1948","journal-title":"J Exp Zool"},{"key":"10.1016\/j.jhsa.2009.06.013_bib33","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0092-8674(93)90391-3","article-title":"FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb","volume":"75","author":"Niswander","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib34","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nature06876","article-title":"Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning","volume":"453","author":"Mariani","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib35","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/82609","article-title":"Fgf8 signalling from the AER is essential for normal limb development","volume":"26","author":"Lewandoski","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib36","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/75644","article-title":"Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development","volume":"25","author":"Sun","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib37","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1242\/dev.124.11.2235","article-title":"The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor","volume":"124","author":"Ohuchi","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib38","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/5096","article-title":"Fgf10 is essential for limb and lung formation","volume":"2","author":"Sekine","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib39","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1242\/dev.125.4.753","article-title":"Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction","volume":"125","author":"Xu","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib40","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1242\/dev.018945","article-title":"The apical ectodermal ridge is a timer for generating distal limb progenitors","volume":"135","author":"Lu","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib41","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1242\/dev.013268","article-title":"FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis","volume":"135","author":"Yu","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib42","series-title":"Epithelia-mesenchymal interactions","first-page":"78","article-title":"Ectoderm-mesenchymal interaction in the origin of wing symmetry","author":"Saunders","year":"1968"},{"key":"10.1016\/j.jhsa.2009.06.013_bib43","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/0092-8674(93)90626-2","article-title":"Sonic hedgehog mediates the polarizing activity of the ZPA","volume":"75","author":"Riddle","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib44","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1006\/dbio.2001.0346","article-title":"Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function","volume":"236","author":"Chiang","year":"2001","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib45","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1242\/dev.121.7.1971","article-title":"Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity","volume":"121","author":"Chan","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib46","doi-asserted-by":"crossref","first-page":"4393","DOI":"10.1242\/dev.124.21.4393","article-title":"Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb","volume":"124","author":"Yang","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.jhsa.2009.06.013_bib47","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0266-7681(98)80140-X","article-title":"Classification of the mirror hand\u2014multiple hand spectrum","volume":"23B","author":"Al-Quattan","year":"1998","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib48","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0092-8674(01)00369-5","article-title":"Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1","volume":"105","author":"Lewis","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib49","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ydbio.2007.05.030","article-title":"Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb","volume":"308","author":"Scherz","year":"2007","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib50","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.devcel.2008.01.008","article-title":"Uncoupling Sonic hedgehog control of pattern and expansion of the developing limb bud","volume":"14","author":"Zhu","year":"2008","journal-title":"Dev Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib51","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/371609a0","article-title":"A positive feedback loop coordinates growth and patterning in the vertebrate limb","volume":"371","author":"Niswander","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib52","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/0092-8674(94)90030-2","article-title":"Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud","volume":"79","author":"Laufer","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib53","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0012-1606(74)80009-6","article-title":"Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo","volume":"39","author":"MacCabe","year":"1974","journal-title":"Dev Biol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib54","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/BF00186694","article-title":"The effect of the ectoderm on the dorsoventral pattern of epidermis, muscles and joints in the developing chick leg: a new model","volume":"193","author":"Akita","year":"1996","journal-title":"Anat Embryol"},{"key":"10.1016\/j.jhsa.2009.06.013_bib55","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0092-8674(95)90103-5","article-title":"Induction of the LIM homeobox gene Lmx-1 by Wnt7a establishes dorsoventral pattern in the vertebrate limb","volume":"83","author":"Riddle","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib56","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/0092-8674(95)90297-X","article-title":"Interaction between two signaling molecules WNT7a and Shh during vertebrate limb development: dorsal signals regulate anteroposterior patterning","volume":"80","author":"Yang","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib57","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/374350a0","article-title":"Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb","volume":"374","author":"Parr","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib58","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0266-7681(02)00084-0","article-title":"Congenital duplication of the palm in a patient with multiple anomalies","volume":"28B","author":"Al-Qattan","year":"2003","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib59","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/01.sap.0000251486.89375.03","article-title":"Congenital duplication of the palm syndrome","volume":"59","author":"Al-Qattan","year":"2007","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib60","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1177\/1753193408099828","article-title":"Congenital duplication of the palm syndrome: gene analysis and the molecular basis of its clinical features","volume":"34E","author":"Al-Qattan","year":"2009","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib61","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1086\/506332","article-title":"Mutations in WNT7A causes a range of limb malformations including Fuhrmann syndrome and Al-Awadi\/Raas-Rotchschild\/Schinzel phocomelia syndrome","volume":"79","author":"Woods","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jhsa.2009.06.013_bib62","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/382360a0","article-title":"The mouse Engrailed-1 gene and ventral limb patterning","volume":"382","author":"Loomis","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jhsa.2009.06.013_bib63","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/00006534-199301000-00027","article-title":"Clam nail deformity of the little finger","volume":"91","author":"Kinoshita","year":"1993","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib64","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4172\/plastic-surgery.1000110","article-title":"Circumferential little finger nail plate","volume":"3","author":"Thoma","year":"1995","journal-title":"Can J Plast Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib65","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/J.JHSE.2007.03.001","article-title":"Dorsal dimelia in Patau syndrome: a case report","volume":"32B","author":"Fattah","year":"2007","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib66","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0266-7681(92)90133-M","article-title":"Congenital palmar nail syndrome","volume":"17B","author":"Rider","year":"1992","journal-title":"J Hand Surg"},{"key":"10.1016\/j.jhsa.2009.06.013_bib67","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S1534-5807(01)00041-7","article-title":"Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse","volume":"1","author":"Mukhopadhyay","year":"2001","journal-title":"Dev Cell"},{"key":"10.1016\/j.jhsa.2009.06.013_bib68","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/ng0598-47","article-title":"Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome","volume":"19","author":"Dreyer","year":"1998","journal-title":"Nat Genet"}],"container-title":["The Journal of Hand Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502309005085?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502309005085?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T12:25:46Z","timestamp":1685103946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0363502309005085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":68,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S0363502309005085"],"URL":"https:\/\/doi.org\/10.1016\/j.jhsa.2009.06.013","relation":{},"ISSN":["0363-5023"],"issn-type":[{"value":"0363-5023","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}