{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T05:32:27Z","timestamp":1772688747926,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Hand Surgery"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.jhsa.2013.03.012","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T20:02:50Z","timestamp":1367870570000},"page":"1071-1078","source":"Crossref","is-referenced-by-count":13,"title":["Apoptosis in Adhesions and the Adhesion-Tendon Gliding Interface: Relationship to Adhesion-Tendon Gliding Mechanics"],"prefix":"10.1016","volume":"38","author":[{"given":"Ya Fang","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Bo","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jhsa.2013.03.012_bib1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0266-7681(88)90077-0","article-title":"Flexor tendon healing","volume":"13","author":"Manske","year":"1988","journal-title":"J Hand Surg Br"},{"issue":"2","key":"10.1016\/j.jhsa.2013.03.012_bib2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.hcl.2004.11.005","article-title":"Clinical outcomes associated with flexor tendon repair","volume":"21","author":"Tang","year":"2005","journal-title":"Hand Clin"},{"issue":"3","key":"10.1016\/j.jhsa.2013.03.012_bib3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jhsa.2011.11.006","article-title":"Complications after flexor tendon repair: a systematic review and meta-analysis","volume":"37","author":"Dy","year":"2012","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.jhsa.2013.03.012_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jhsa.2009.10.021","article-title":"Molecular events of cellular apoptosis and proliferation in the early tendon healing period","volume":"35","author":"Wu","year":"2010","journal-title":"J Hand Surg Am"},{"issue":"2","key":"10.1016\/j.jhsa.2013.03.012_bib5","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jhsa.2011.10.049","article-title":"Cellular apoptosis and proliferation in the middle and late intrasynovial tendon healing periods","volume":"37","author":"Wu","year":"2012","journal-title":"J Hand Surg Am"},{"issue":"5","key":"10.1016\/j.jhsa.2013.03.012_bib6","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/j.1524-475X.2007.00276.x","article-title":"Increased apoptosis at the late stage of tendon healing","volume":"15","author":"Lui","year":"2007","journal-title":"Wound Repair Regen"},{"issue":"5","key":"10.1016\/j.jhsa.2013.03.012_bib7","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.2353\/ajpath.2009.090380","article-title":"The cellular biology of flexor tendon adhesion formation: an old problem in a new paradigm","volume":"175","author":"Wong","year":"2009","journal-title":"Am J Pathol"},{"issue":"5","key":"10.1016\/j.jhsa.2013.03.012_bib8","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1054\/jhsb.2001.0581","article-title":"Development of polyvinyl alcohol-hydrogel (PVA-H) shields with a high water content for tendon injury repair","volume":"26","author":"Kobayashi","year":"2001","journal-title":"J Hand Surg Br"},{"issue":"10","key":"10.1016\/j.jhsa.2013.03.012_bib9","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.jhsa.2009.08.012","article-title":"Strength of tendon repair decreases in the presence of an intact A2 pulley: biomechanical study in a chicken model","volume":"34","author":"Cao","year":"2009","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.jhsa.2013.03.012_bib10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1177\/1753193410381674","article-title":"Tendon adhesion measured by a video-assisted gliding test in a chicken model","volume":"36","author":"Fu","year":"2011","journal-title":"J Hand Surg Eur Vol"},{"issue":"4","key":"10.1016\/j.jhsa.2013.03.012_bib11","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1177\/1753193411425329","article-title":"Relative contribution of tissue oedema and the presence of an A2 pulley to resistance to flexor tendon movement: an in vitro and in vivo study","volume":"37","author":"Wu","year":"2012","journal-title":"J Hand Surg Eur"},{"issue":"6","key":"10.1016\/j.jhsa.2013.03.012_bib12","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/S0363-5023(03)00428-3","article-title":"Effects of superficialis tendon repairs on lacerated profundus tendons within or proximal to the A2 pulley: an in vivo study in chickens","volume":"28","author":"Xu","year":"2003","journal-title":"J Hand Surg Am"},{"key":"10.1016\/j.jhsa.2013.03.012_bib13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/01.blo.0000246564.96208.b0","article-title":"A2 pulley incision or one slip of the superficialis improves flexor tendon repairs","volume":"456","author":"Tang","year":"2007","journal-title":"Clin Orthop Relat Res"},{"issue":"5","key":"10.1016\/j.jhsa.2013.03.012_bib14","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.2106\/JBJS.F.01188","article-title":"Adeno-associated virus-2-mediated bFGF gene transfer to digital flexor tendons significantly increases healing strength","volume":"90","author":"Tang","year":"2008","journal-title":"J Bone Joint Surg Am"},{"issue":"1","key":"10.1016\/j.jhsa.2013.03.012_bib15","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0002-9440(10)64725-6","article-title":"Determination of the proliferation and apoptotic index in adrenocorticotropin-secreting pituitary tumors: comparison between micro- and macroadenomas","volume":"156","author":"Losa","year":"2000","journal-title":"Am J Pathol"},{"issue":"9","key":"10.1016\/j.jhsa.2013.03.012_bib16","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1200\/JCO.1999.17.9.2728","article-title":"Prognostic significance of apoptotic index in completely resected non\u2013small-cell lung cancer","volume":"17","author":"Tanaka","year":"1999","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.jhsa.2013.03.012_bib17","doi-asserted-by":"crossref","first-page":"277","DOI":"10.12968\/jowc.2005.14.6.26792","article-title":"Effect of glycaemic control on apoptosis in diabetic wounds","volume":"14","author":"Rai","year":"2005","journal-title":"J Wound Care"},{"key":"10.1016\/j.jhsa.2013.03.012_bib18","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1365-2818.2005.01466.x","article-title":"Reconstruct: a free editor for serial section microscopy","volume":"218","author":"Fiala","year":"2005","journal-title":"J Microsc"},{"issue":"3","key":"10.1016\/j.jhsa.2013.03.012_bib19","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2106\/00004623-200303000-00025","article-title":"Biologic aspects of flexor tendon laceration and repair","volume":"85","author":"Beredjiklian","year":"2003","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"10.1016\/j.jhsa.2013.03.012_bib20","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.jbiomech.2003.11.005","article-title":"Biomechanics of tendon injury and repair","volume":"37","author":"Lin","year":"2004","journal-title":"J Biomech"},{"issue":"2","key":"10.1016\/j.jhsa.2013.03.012_bib21","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1053\/jhsu.2000.jhsu25a0214","article-title":"Development of flexor tendon surgery: twenty-five years of progress","volume":"25","author":"Strickland","year":"2000","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.jhsa.2013.03.012_bib22","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jhsa.2007.09.007","article-title":"Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options","volume":"33","author":"James","year":"2008","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.jhsa.2013.03.012_bib23","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1475-2867-12-36","article-title":"Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines","volume":"12","author":"Teodoro","year":"2012","journal-title":"Cancer Cell Int"},{"issue":"12","key":"10.1016\/j.jhsa.2013.03.012_bib24","doi-asserted-by":"crossref","first-page":"8106","DOI":"10.4049\/jimmunol.174.12.8106","article-title":"Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema","volume":"174","author":"Zheng","year":"2005","journal-title":"J Immunol"},{"issue":"4","key":"10.1016\/j.jhsa.2013.03.012_bib25","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/01.MP.0000062657.30170.92","article-title":"Identifying and quantifying apoptosis: navigating technical pitfalls","volume":"16","author":"Garrity","year":"2003","journal-title":"Mod Pathol"}],"container-title":["The Journal of Hand Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502313003729?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502313003729?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T01:29:22Z","timestamp":1539653362000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0363502313003729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0363502313003729"],"URL":"https:\/\/doi.org\/10.1016\/j.jhsa.2013.03.012","relation":{},"ISSN":["0363-5023"],"issn-type":[{"value":"0363-5023","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}