{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:12:13Z","timestamp":1788567133648,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Hand Surgery"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.jhsa.2017.03.003","type":"journal-article","created":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T05:30:38Z","timestamp":1493616638000},"page":"321-328.e3","source":"Crossref","is-referenced-by-count":95,"title":["Injectable Collagenase Versus Percutaneous Needle Fasciotomy for Dupuytren Contracture in Proximal Interphalangeal Joints: A\u00a0Randomized Controlled Trial"],"prefix":"10.1016","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2089-7113","authenticated-orcid":false,"given":"Simon Toftgaard","family":"Skov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3678-7832","authenticated-orcid":false,"given":"Therkel","family":"Bisgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"S\u00f8ndergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6868-7513","authenticated-orcid":false,"given":"Jeppe","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.jhsa.2017.03.003_bib1","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1038\/nrrheum.2010.180","article-title":"Scientific understanding and clinical management of Dupuytren disease","volume":"6","author":"Shih","year":"2010","journal-title":"Nat Rev Rheumatol"},{"issue":"10","key":"10.1016\/j.jhsa.2017.03.003_bib2","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1056\/NEJMoa0810866","article-title":"Injectable collagenase Clostridium histolyticum for Dupuytren\u2019s contracture","volume":"361","author":"Hurst","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.jhsa.2017.03.003_bib3","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.jhsa.2012.09.028","article-title":"Dupuytren contracture recurrence following treatment with collagenase Clostridium histolyticum (CORDLESS Study): 3-year data","volume":"38","author":"Peimer","year":"2013","journal-title":"J\u00a0Hand Surg Am"},{"issue":"8","key":"10.1016\/j.jhsa.2017.03.003_bib4","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1016\/j.jhsa.2015.04.036","article-title":"Dupuytren contracture recurrence following treatment with collagenase Clostridium histolyticum (CORDLESS [Collagenase Option for Reduction of Dupuytren Long-Term Evaluation of Safety Study]): 5-year data","volume":"40","author":"Peimer","year":"2015","journal-title":"J\u00a0Hand Surg Am"},{"issue":"9","key":"10.1016\/j.jhsa.2017.03.003_bib5","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/j.jhsa.2016.06.014","article-title":"Comparison of treatment outcome after collagenase and needle fasciotomy for Dupuytren contracture: a randomized, single-blinded, clinical trial with a 1-year follow-up","volume":"41","author":"Str\u00f6mberg","year":"2016","journal-title":"J\u00a0Hand Surg Am"},{"issue":"6","key":"10.1016\/j.jhsa.2017.03.003_bib6","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1177\/1753193415617385","article-title":"One-year results of needle fasciotomy and collagenase injection in treatment of Dupuytren\u2019s contracture: a two-centre prospective randomized clinical trial","volume":"41","author":"Scherman","year":"2016","journal-title":"J\u00a0Hand Surg Eur Vol"},{"issue":"90","key":"10.1016\/j.jhsa.2017.03.003_bib7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta19900","article-title":"Collagenase Clostridium histolyticum for the treatment of Dupuytren\u2019s contracture: systematic review and economic evaluation","volume":"19","author":"Brazzelli","year":"2015","journal-title":"Health Technol Assess"},{"key":"10.1016\/j.jhsa.2017.03.003_bib8","first-page":"238","article-title":"Le traitement m\u00e9dical de la maladie de Dupuytren","author":"Lermusiaux","year":"1979","journal-title":"L\u2019Actualit\u00e9 Rhumatol Paris Expans Sci Publ"},{"key":"10.1016\/j.jhsa.2017.03.003_bib9","doi-asserted-by":"crossref","unstructured":"Adams W. On Contractions of the Fingers (Dupuytren\u2019s and Congenital Contractions) and Hammer-Toe. London: Churchill;\u00a01892.","DOI":"10.1097\/00000441-189211000-00013"},{"issue":"5","key":"10.1016\/j.jhsa.2017.03.003_bib10","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.jhsa.2006.02.021","article-title":"A\u00a0comparison of the direct outcomes of percutaneous needle fasciotomy and limited fascietctomy for Dupuytren\u2019s disease: a 6-week follow up study","volume":"31","author":"van Rijssen","year":"2006","journal-title":"J\u00a0Hand Surg Am"},{"issue":"5","key":"10.1016\/j.jhsa.2017.03.003_bib11","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.jhsb.2006.03.174","article-title":"Percutaneous needle fasciotomy in Dupuytren\u2019s disease","volume":"31","author":"van Rijssen","year":"2006","journal-title":"J\u00a0Hand Surg Eur Vol"},{"issue":"7","key":"10.1016\/j.jhsa.2017.03.003_bib12","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1177\/1753193411407245","article-title":"Percutaneous needle fasciotomy for primary Dupuytren\u2019s contracture","volume":"36","author":"Rahr","year":"2011","journal-title":"J\u00a0Hand Surg Eur Vol"},{"issue":"2","key":"10.1016\/j.jhsa.2017.03.003_bib13","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1097\/PRS.0b013e31823aea95","article-title":"Five-year results of a randomized clinical trial on treatment in Dupuytren\u02bcs disease","volume":"129","author":"van Rijssen","year":"2012","journal-title":"Plast Reconstr Surg"},{"issue":"11","key":"10.1016\/j.jhsa.2017.03.003_bib14","first-page":"808","article-title":"Non-surgical treatment of Dupuytren disease using needle fasciotomy","volume":"60","author":"Badois","year":"1993","journal-title":"Rev Rhum Ed Fr"},{"issue":"5","key":"10.1016\/j.jhsa.2017.03.003_bib15","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/S0266-7681(03)00013-5","article-title":"Percutaneous needle aponeurotomy: complications and results","volume":"28","author":"Foucher","year":"2003","journal-title":"J\u00a0Hand Surg Br"},{"issue":"2","key":"10.1016\/j.jhsa.2017.03.003_bib16","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1177\/1753193413519926","article-title":"Collagenase Clostridium histolyticum in patients with Dupuytren\u2019s contracture: results from POINT X, an open-label study of clinical and patient-reported outcomes","volume":"40","author":"Warwick","year":"2014","journal-title":"J\u00a0Hand Surg Eur Vol"},{"key":"10.1016\/j.jhsa.2017.03.003_bib17","unstructured":"European Medicines Agency. Xiapex product information. Available from: http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/EPAR_-_Product_Information\/human\/002048\/WC500103373.pdf. Accessed October 26, 2016."},{"issue":"2","key":"10.1016\/j.jhsa.2017.03.003_bib18","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/S0894-1130(01)80043-0","article-title":"Measuring the whole or the parts?","volume":"14","author":"Beaton","year":"2001","journal-title":"J\u00a0Hand Ther"},{"issue":"48","key":"10.1016\/j.jhsa.2017.03.003_bib19","first-page":"3333","article-title":"Validation of questionnaire for condtions of the upper extremity","volume":"172","author":"Herup","year":"2010","journal-title":"Ugeskr L\u00e6ger"},{"issue":"4","key":"10.1016\/j.jhsa.2017.03.003_bib20","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.jhsa.2014.01.028","article-title":"Letters to the editor: cold intolerance following collagenase Clostridium histolyticum treatment for Dupuytren contracture","volume":"39","author":"King","year":"2014","journal-title":"J\u00a0Hand Surg Am"},{"issue":"12","key":"10.1016\/j.jhsa.2017.03.003_bib21","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.1016\/j.jhsa.2010.08.007","article-title":"Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren\u2019s disease","volume":"35","author":"Gilpin","year":"2010","journal-title":"J\u00a0Hand Surg Am"},{"issue":"5","key":"10.1016\/j.jhsa.2017.03.003_bib22","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/j.jhsa.2015.02.018","article-title":"Efficacy and safety of collagenase Clostridium histolyticum in the treatment of proximal interphalangeal joints in Dupuytren contracture: combined analysis of 4 phase 3 clinical trials","volume":"40","author":"Badalamente","year":"2015","journal-title":"J\u00a0Hand Surg Am"},{"issue":"12","key":"10.1016\/j.jhsa.2017.03.003_bib23","doi-asserted-by":"publisher","first-page":"2377","DOI":"10.1016\/j.jhsa.2013.08.096","article-title":"A\u00a0comparison of percutaneous needle fasciotomy and collagenase injection for Dupuytren disease","volume":"38","author":"Nydick","year":"2013","journal-title":"J\u00a0Hand Surg Am"},{"issue":"6","key":"10.1016\/j.jhsa.2017.03.003_bib24","first-page":"671","article-title":"Dupuytren\u2019s disease: Outcome of the proximal interphalangeal joint in isolated fifth ray involvement","volume":"72","author":"Van Giffen","year":"2006","journal-title":"Acta Orthop Belg"},{"issue":"8","key":"10.1016\/j.jhsa.2017.03.003_bib25","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1302\/0301-620X.95B8.31822","article-title":"Cost-effectiveness in the management of Dupuytren\u2019s contracture. A Canadian cost-utility analysis of current and future management strategies","volume":"95-B","author":"Baltzer","year":"2013","journal-title":"Bone Joint J"},{"issue":"10","key":"10.1016\/j.jhsa.2017.03.003_bib26","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/j.jhsa.2016.07.090","article-title":"The impact of collagenase Clostridium histolyticum introduction on Dupuytren treatment patterns in the United States","volume":"41","author":"Zhao","year":"2016","journal-title":"J\u00a0Hand Surg Am"}],"container-title":["The Journal of Hand Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502316308176?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502316308176?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T12:18:11Z","timestamp":1569154691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0363502316308176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0363502316308176"],"URL":"https:\/\/doi.org\/10.1016\/j.jhsa.2017.03.003","relation":{},"ISSN":["0363-5023"],"issn-type":[{"value":"0363-5023","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]}}}