{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:17:05Z","timestamp":1762899425343},"reference-count":20,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Hand Surgery"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.jhsa.2017.04.011","type":"journal-article","created":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T11:45:31Z","timestamp":1495626331000},"page":"564-568","source":"Crossref","is-referenced-by-count":4,"title":["Anesthetic Neurotoxicity in Congenital Hand Surgery: An Overview of the Evidence and Advice for Counseling Parents"],"prefix":"10.1016","volume":"42","author":[{"given":"Michael S.","family":"Gart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santhanam","family":"Suresh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua M.","family":"Adkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhsa.2017.04.011_bib1","unstructured":"SmartTots Consensus Statement. 2015. Available at: http:\/\/smarttots.org\/about\/consensus-statement\/. Accessed August 15,\u00a02016."},{"issue":"1","key":"10.1016\/j.jhsa.2017.04.011_bib2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0094-1298(20)31274-8","article-title":"Timing and decision-making in the treatment of congenital upper extremity deformities","volume":"17","author":"Netscher","year":"1990","journal-title":"Clin Plast Surg"},{"key":"10.1016\/j.jhsa.2017.04.011_bib3","series-title":"The Growing Hand","first-page":"71","article-title":"Functional development of the hand","author":"Erhardt","year":"2000"},{"issue":"5455","key":"10.1016\/j.jhsa.2017.04.011_bib4","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1126\/science.287.5455.1056","article-title":"Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome","volume":"287","author":"Ikonomidou","year":"2000","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jhsa.2017.04.011_bib5","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1213\/ane.0b013e3181733ef8","article-title":"CON: the toxic effects of anesthetics in the developing brain: the clinical perspective","volume":"106","author":"Loepke","year":"2008","journal-title":"Anesth Analg"},{"issue":"6","key":"10.1016\/j.jhsa.2017.04.011_bib6","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1213\/ane.0b013e318167ad77","article-title":"An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function","volume":"106","author":"Loepke","year":"2008","journal-title":"Anesth Analg"},{"issue":"3","key":"10.1016\/j.jhsa.2017.04.011_bib7","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1523\/JNEUROSCI.23-03-00876.2003","article-title":"Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits","volume":"23","author":"Jevtovic-Todorovic","year":"2003","journal-title":"J\u00a0Neurosci"},{"issue":"4","key":"10.1016\/j.jhsa.2017.04.011_bib8","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/ana.23652","article-title":"Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain","volume":"72","author":"Brambrink","year":"2012","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1016\/j.jhsa.2017.04.011_bib9","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/ALN.0b013e318242b2cd","article-title":"Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain","volume":"116","author":"Brambrink","year":"2012","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.jhsa.2017.04.011_bib10","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/ALN.0b013e3181d049cd","article-title":"Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain","volume":"112","author":"Brambrink","year":"2010","journal-title":"Anesthesiology"},{"issue":"1","key":"10.1016\/j.jhsa.2017.04.011_bib11","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/pan.12325","article-title":"Anesthetic neurotoxicity: what to tell the parents?","volume":"24","author":"Nemergut","year":"2014","journal-title":"Paediatr Anaesth"},{"issue":"2","key":"10.1016\/j.jhsa.2017.04.011_bib12","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ntt.2011.01.001","article-title":"Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys","volume":"33","author":"Paule","year":"2011","journal-title":"Neurotoxicol Teratol"},{"issue":"1","key":"10.1016\/j.jhsa.2017.04.011_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/toxsci\/kfm084","article-title":"Ketamine-induced neuronal cell death in the perinatal rhesus monkey","volume":"98","author":"Slikker","year":"2007","journal-title":"Toxicol Sci"},{"issue":"5","key":"10.1016\/j.jhsa.2017.04.011_bib14","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.ntt.2011.06.003","article-title":"Inhalation anesthetic-induced neuronal damage in the developing rhesus monkey","volume":"33","author":"Zou","year":"2011","journal-title":"Neurotoxicol Teratol"},{"issue":"3","key":"10.1016\/j.jhsa.2017.04.011_bib15","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/bja\/aet469","article-title":"Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions","volume":"113","author":"Deng","year":"2014","journal-title":"Br J Anaesth"},{"issue":"3","key":"10.1016\/j.jhsa.2017.04.011_bib16","doi-asserted-by":"crossref","first-page":"e476","DOI":"10.1542\/peds.2011-3822","article-title":"Long-term differences in language and cognitive function after childhood exposure to anesthesia","volume":"130","author":"Ing","year":"2012","journal-title":"Pediatrics"},{"issue":"21","key":"10.1016\/j.jhsa.2017.04.011_bib17","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1001\/jama.2016.6967","article-title":"Association between a single general anesthesia exposure before age 36 months and neurocognitive outcomes in later childhood","volume":"315","author":"Sun","year":"2016","journal-title":"JAMA"},{"issue":"10015","key":"10.1016\/j.jhsa.2017.04.011_bib18","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0140-6736(15)00608-X","article-title":"Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial","volume":"387","author":"Davidson","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.jhsa.2017.04.011_bib19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.cct.2014.12.020","article-title":"Neurodevelopment of children exposed to anesthesia: design of the Mayo Anesthesia Safety in Kids (MASK) study","volume":"41","author":"Gleich","year":"2015","journal-title":"Contemp Clin Trials"},{"key":"10.1016\/j.jhsa.2017.04.011_bib20","unstructured":"U.S. FDA Drug Safety Communication: FDA review results in new warnings about using general anesthetics and sedation drugs in young children and pregnant women. 2016. Available at: http:\/\/www.fda.gov\/Drugs\/DrugSafety\/ucm53256.htm. Accessed December 23,\u00a02016."}],"container-title":["The Journal of Hand Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502317300515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0363502317300515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T11:01:23Z","timestamp":1602154883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0363502317300515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S0363502317300515"],"URL":"https:\/\/doi.org\/10.1016\/j.jhsa.2017.04.011","relation":{},"ISSN":["0363-5023"],"issn-type":[{"value":"0363-5023","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}