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Smaller numbers of patients with dominant dystrophic, junctional, and simplex types of epidermolysis bullosa are also at risk of this complication. Surgical intervention is commonly performed to correct these deformities, but recurrence and the need for repeated surgery are common. Higher numbers of epidermolysis bullosa patients also develop musculoskeletal contractures in other anatomic sites, further impairing overall function. Lifetable analyses not only better project the cumulative risk of mitten deformities and other contractures but also emphasize the need for early surveillance and intervention, since both of these musculoskeletal complications may occur within the first year of life.<\/jats:p>","DOI":"10.1016\/j.jhsb.2004.07.006","type":"journal-article","created":{"date-parts":[[2004,11,12]],"date-time":"2004-11-12T12:22:52Z","timestamp":1100262172000},"page":"14-22","source":"Crossref","is-referenced-by-count":86,"title":["Pseudosyndactyly and Musculoskeletal Contractures in Inherited Epidermolysis Bullosa: Experience of the National Epidermolysis Bullosa Registry, 1986\u20132002"],"prefix":"10.1177","volume":"30","author":[{"given":"J.-D.","family":"FINE","sequence":"first","affiliation":[{"name":"From the National Epidermolysis Bullosa Registry, Nashville, Tennessee, the Department of Medicine (Dermatology), Vanderbilt University School of Medicine, Nashville, Tennessee, and the Departments of 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