{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:08:35Z","timestamp":1775092115448,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jhandtherapy.org","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hand Therapy"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jht.2024.10.002","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T12:21:29Z","timestamp":1736166089000},"page":"80-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["The effect of manual lymphatic drainage on intraneural edema of the median nerve in patients with carpal tunnel syndrome: A randomized controlled trial"],"prefix":"10.1016","volume":"38","author":[{"given":"Nil\u00fcfer","family":"Kablan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emel","family":"Mete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilin\u00e7 Do\u011fru\u00f6z","family":"Karatekin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Temel","family":"Tombul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"103044","key":"10.1016\/j.jht.2024.10.002_bib1","first-page":"1","article-title":"Carpal tunnel mechanics and its relevance to carpal tunnel syndrome","volume":"87","author":"Li","year":"2023","journal-title":"Hum Mov Sci"},{"issue":"1","key":"10.1016\/j.jht.2024.10.002_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/2309499019825572","article-title":"Incidence of referred carpal tunnel syndrome and carpal tunnel release surgery in the general population: increase over time and regional variations","volume":"27","author":"Tadjerbashi","year":"2019","journal-title":"J Orthop Surg"},{"issue":"5","key":"10.1016\/j.jht.2024.10.002_bib3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.2106\/00004623-198971050-00006","article-title":"Measurement of pressure in the carpal canal before and after endoscopic management of carpal tunnel syndrome.","volume":"71","author":"Okutsu","year":"1989","journal-title":"J Bone Joint Surg Am"},{"issue":"4","key":"10.1016\/j.jht.2024.10.002_bib4","doi-asserted-by":"crossref","first-page":"851","DOI":"10.5603\/FM.a2021.0121","article-title":"Carpal tunnel syndrome: state-of-the-art review","volume":"81","author":"Osiak","year":"2022","journal-title":"Folia Morphol"},{"issue":"9","key":"10.1016\/j.jht.2024.10.002_bib5","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/jor.20599","article-title":"Effect of wrist posture on carpal tunnel pressure while typing","volume":"26","author":"Rempel","year":"2008","journal-title":"J Orthop Res"},{"issue":"1","key":"10.1016\/j.jht.2024.10.002_bib6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0363-5023(81)80003-2","article-title":"Effects of graded compression on intraneural blood flow: an in vivo study on rabbit tibial nerve","volume":"6","author":"Rydevik","year":"1981","journal-title":"J Hand Surg Am"},{"issue":"1","key":"10.1016\/j.jht.2024.10.002_bib7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2174\/1874325001206010069","article-title":"Suppl 1: carpal tunnel syndrome: a review of the recent literature","volume":"6","author":"Ibrahim","year":"2012","journal-title":"Open Orthop J"},{"key":"10.1016\/j.jht.2024.10.002_bib8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s10072-009-0213-9","article-title":"Diagnosis, treatment and follow-up of the carpal tunnel syndrome: a review","volume":"31","author":"Alfonso","year":"2010","journal-title":"Neurol Sci"},{"issue":"10","key":"10.1016\/j.jht.2024.10.002_bib9","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2519\/jospt.2004.34.10.565","article-title":"Clinical and electrodiagnostic testing of carpal tunnel syndrome: a narrative review","volume":"34","author":"MacDermid","year":"2004","journal-title":"J Orthop Sports Phys Ther"},{"issue":"4","key":"10.1016\/j.jht.2024.10.002_bib10","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/joa.13124","article-title":"Role of fasciae around the median nerve in pathogenesis of carpal tunnel syndrome: microscopic and ultrasound study","volume":"236","author":"Stecco","year":"2020","journal-title":"J Anat"},{"issue":"2","key":"10.1016\/j.jht.2024.10.002_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1197\/j.jht.2005.02.001","article-title":"Pathomechanics of peripheral nerve loading: evidence in carpal tunnel syndrome","volume":"18","author":"Keir","year":"2005","journal-title":"J Hand Ther"},{"issue":"2","key":"10.1016\/j.jht.2024.10.002_bib12","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/00002060-200202000-00006","article-title":"Treatment of carpal tunnel syndrome with nerve and tendon gliding exercises","volume":"81","author":"Akalin","year":"2002","journal-title":"Am J Phys Med Rehabil"},{"issue":"11-12","key":"10.1016\/j.jht.2024.10.002_bib13","doi-asserted-by":"crossref","first-page":"E2049","DOI":"10.1093\/milmed\/usaa222","article-title":"Splinting in carpal tunnel syndrome: the optimal duration","volume":"185","author":"Gatheridge","year":"2020","journal-title":"Mil Med"},{"issue":"6","key":"10.1016\/j.jht.2024.10.002_bib14","first-page":"3","article-title":"Effect of neural mobilisation versus nerve and tendon gliding exercises in carpal tunnel syndrome: a randomised clinical trial","volume":"14","author":"Vaidya","year":"2020","journal-title":"J Clin Diagnostic Res"},{"issue":"2","key":"10.1016\/j.jht.2024.10.002_bib15","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00264-021-05272-2","article-title":"The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis","volume":"46","author":"Jim\u00e9nez-del-Barrio","year":"2022","journal-title":"Int Orthop"},{"issue":"1","key":"10.1016\/j.jht.2024.10.002_bib16","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5114\/pq.2019.83057","article-title":"Effect of myofascial release on electrophysiological and clinical measures of pregnant women with carpal tunnel syndrome","volume":"27","author":"Hamoda","year":"2019","journal-title":"Physiother Q"},{"issue":"11","key":"10.1016\/j.jht.2024.10.002_bib17","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1590\/0004-282x20170152","article-title":"Conservative therapeutic management of carpal tunnel syndrome","volume":"75","author":"Martins","year":"2017","journal-title":"Arq Neuropsiquiatr"},{"issue":"7","key":"10.1016\/j.jht.2024.10.002_bib18","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/aas.13593","article-title":"The Extended Starling principle needs clinical validation","volume":"64","author":"Hahn","year":"2020","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.jht.2024.10.002_bib19","unstructured":"F\u00f6ldi E and\u00a0F\u00f6ldi M. Manual lymph drainage according to E. Vodder. In: F\u00f6ldi\u2019s Textbook of Lymphology: For Physicians and Lymphedema Therapists. 3RD ed. Elsevier Health Sciences; 2012:464\u2013477."},{"issue":"1","key":"10.1016\/j.jht.2024.10.002_bib20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1089\/lrb.2019.0091","article-title":"Investigation of the less known effects of manual lymphatic drainage: a narrative review","volume":"20","author":"Schingale","year":"2022","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.jht.2024.10.002_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ctcp.2021.101469","article-title":"The use of manual lymphatic drainage on clinical presentation of musculoskeletal injuries: a systematic review","volume":"45","author":"Provencher","year":"2021","journal-title":"Complement Ther Clin Pract"},{"issue":"4","key":"10.1016\/j.jht.2024.10.002_bib22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1600-0404.1997.tb00271.x","article-title":"Neurophysiological classification and sensitivity in 500 carpal tunnel syndrome hands","volume":"96","author":"Padua","year":"1997","journal-title":"Acta Neurologica Scandinavica"},{"issue":"3","key":"10.1016\/j.jht.2024.10.002_bib23","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1177\/0269215518805213","article-title":"Is manual therapy based on neurodynamic techniques effective in the treatment of carpal tunnel syndrome? A randomized controlled trial","volume":"33","author":"Wolny","year":"2019","journal-title":"Clin Rehabil"},{"issue":"1269","key":"10.1016\/j.jht.2024.10.002_bib24","first-page":"1","article-title":"Electrodiagnostic studies in the surgical treatment of carpal tunnel syndrome\u2014a systematic review","volume":"10","author":"Osiak","year":"2021","journal-title":"J Clin Med"},{"issue":"6","key":"10.1016\/j.jht.2024.10.002_bib25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1097\/PHM.0000000000000877","article-title":"Comparison between effectiveness of ultrasound-guided corticosteroid injection above versus below the median nerve in mild to moderate carpal tunnel syndrome: a randomized controlled trial","volume":"97","author":"Babaei-Ghazani","year":"2018","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.jht.2024.10.002_bib26","doi-asserted-by":"crossref","unstructured":"Ghasemi-Rad M, Nosair E, Vegh A, et al. A handy review of carpal tunnel syndrome: from anatomy to diagnosis and treatment. World J Radiol 201428;6(6):284\u2013300. doi:10.4329\/wjr.v6.i6.284.","DOI":"10.4329\/wjr.v6.i6.284"},{"issue":"7","key":"10.1016\/j.jht.2024.10.002_bib27","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1093\/rheumatology\/keh190","article-title":"Ultrasonography versus nerve conduction study in patients with carpal tunnel syndrome: substantive or complementary tests?","volume":"43","author":"El Miedany","year":"2004","journal-title":"Rheumatology (Oxford)"},{"issue":"3","key":"10.1016\/j.jht.2024.10.002_bib28","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/jcu.20551","article-title":"Sonographic measurement of cross-sectional area of the median nerve in the diagnosis of carpal tunnel syndrome: correlation with nerve conduction studies","volume":"37","author":"Moran","year":"2009","journal-title":"J Clin Ultrasound"},{"issue":"2","key":"10.1016\/j.jht.2024.10.002_bib29","doi-asserted-by":"crossref","first-page":"57","DOI":"10.31609\/jpmrs.2019-70503","article-title":"Evaluation of wrist range of motion and hand grip strength in women with the diagnosis of carpal tunnel syndrome: a controlled study","volume":"23","author":"Paker","year":"2020","journal-title":"J PMR Sci"},{"issue":"11","key":"10.1016\/j.jht.2024.10.002_bib30","doi-asserted-by":"crossref","first-page":"2","DOI":"10.18103\/mra.v7i11.2009","article-title":"Pain threshold by pressure algometry in the carpal tunnel syndrome","volume":"7","author":"Bernardino","year":"2019","journal-title":"Med Res Arch"},{"issue":"11","key":"10.1016\/j.jht.2024.10.002_bib31","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.jpain.2006.04.003","article-title":"The pain quality assessment scale: assessment of pain quality in carpal tunnel syndrome","volume":"7","author":"Jensen","year":"2006","journal-title":"J Pain"},{"issue":"20","key":"10.1016\/j.jht.2024.10.002_bib32","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1080\/09638280600621469","article-title":"Assessment of symptom severity and functional status in patients with carpal tunnel syndrome: reliability and validity of the Turkish version of the Boston questionnaire","volume":"28","author":"Sezgin","year":"2006","journal-title":"Disabil Rehabil"},{"issue":"80","key":"10.1016\/j.jht.2024.10.002_bib33","first-page":"1","article-title":"Associations of cardiovascular risk factors, carotid intima-media thickness and manifest atherosclerotic vascular disease with carpal tunnel syndrome","volume":"12","author":"Shiri","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"issue":"F1000 Faculty Rev","key":"10.1016\/j.jht.2024.10.002_bib34","first-page":"1","article-title":"Understanding central sensitization for advances in management of carpal tunnel syndrome","volume":"9","author":"Fern\u00e1ndez-de-las-pe\u00f1as","year":"2020","journal-title":"F1000Research"},{"key":"10.1016\/j.jht.2024.10.002_bib35","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jpsychores.2019.109820","article-title":"Influence of illness perceptions, psychological distress and pain catastrophizing on self-reported symptom severity and functional status in patients with carpal tunnel syndrome","volume":"126","author":"Sun","year":"2019","journal-title":"J Psychosom Res"}],"container-title":["Journal of Hand Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894113024001467?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0894113024001467?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T16:32:42Z","timestamp":1740846762000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0894113024001467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0894113024001467"],"URL":"https:\/\/doi.org\/10.1016\/j.jht.2024.10.002","relation":{},"ISSN":["0894-1130"],"issn-type":[{"value":"0894-1130","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of manual lymphatic drainage on intraneural edema of the median nerve in patients with carpal tunnel syndrome: A randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Hand Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jht.2024.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}