{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:02:08Z","timestamp":1774353728472,"version":"3.50.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"AMY Information and Planning"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.jiac.2017.08.008","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T13:16:30Z","timestamp":1507900590000},"page":"814-819","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Influence of co-infection complicated with human papillomavirus on cervical intraepithelial neoplasia development in patients with atypical squamous cells of undetermined significance"],"prefix":"10.1016","volume":"23","author":[{"given":"Hisami","family":"Kiseki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Tsukahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsumi","family":"Tajima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Horimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiko","family":"Hashimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2017.08.008_bib1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F","article-title":"Human papillomavirus is a necessary cause of invasive cervical cancer worldwide","volume":"189","author":"Walboomers","year":"1999","journal-title":"J\u00a0Pathol"},{"key":"10.1016\/j.jiac.2017.08.008_bib2","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1056\/NEJMoa061741","article-title":"Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions","volume":"356","author":"Future II Study Group","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jiac.2017.08.008_bib3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/oxfordjournals.jncimonographs.a003479","article-title":"Chapter 1: human papillomavirus and cervical cancer\u2013burden and assessment of causality","volume":"31","author":"Bosch","year":"2003","journal-title":"J\u00a0Natl Cancer Inst Monogr"},{"key":"10.1016\/j.jiac.2017.08.008_bib4","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1001\/jama.287.16.2114","article-title":"The 2001 Bethesda System: terminology for reporting results of cervical cytology","volume":"287","author":"Solomon","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.jiac.2017.08.008_bib5","series-title":"Guideline for gynecological practice in Japan 2017","first-page":"42","author":"Guideline for gynecological practice in Japan 2017","year":"2017"},{"key":"10.1016\/j.jiac.2017.08.008_bib6","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1365-2303.2008.00623.x","article-title":"European guidelines for quality assurance in cervical cancer screening: recommendations for clinical management of abnormal cervical cytology, part 1","volume":"19","author":"Jordan","year":"2008","journal-title":"Cytopathology"},{"key":"10.1016\/j.jiac.2017.08.008_bib7","first-page":"e111","article-title":"Practice bulletin no. 168: cervical cancer screening and prevention","volume":"128","author":"Committee on Practice Bulletins gynecology","year":"2016","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jiac.2017.08.008_bib8","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.ajog.2007.07.047","article-title":"2006 American Society for Colposcopy and Cervical Pathology-sponsored Consensus Conference. 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests","volume":"197","author":"Wright","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jiac.2017.08.008_bib9","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1309\/AJCPZ5JY6FCVNMOT","article-title":"ATHENA (Addressing THE Need for Advanced HPV Diagnostics) HPV Study Group. High-risk human papillomavirus testing in women with ASC-US cytology: results from the ATHENA HPV study","volume":"135","author":"Stoler","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jiac.2017.08.008_bib10","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1016\/S0140-6736(82)91273-9","article-title":"Human genital cancer: synergism between two virus infections or synergism between a virus infection and initiating events?","volume":"2","author":"zur Hausen","year":"1982","journal-title":"Lancet"},{"key":"10.1016\/j.jiac.2017.08.008_bib11","first-page":"XE01","article-title":"Association of genital infections other than human papillomavirus with pre-invasive and invasive cervical neoplasia","volume":"10","author":"Ghosh","year":"2016","journal-title":"J\u00a0Clin Diagn Res"},{"key":"10.1016\/j.jiac.2017.08.008_bib12","first-page":"165","article-title":"Pathogenesis of genital HPV infection","volume":"69","author":"Schneider","year":"1993","journal-title":"Genitourin Med"},{"key":"10.1016\/j.jiac.2017.08.008_bib13","article-title":"Chlamydia Trachomatis infection-associated risk of cervical cancer: a meta-analysis","volume":"95","author":"Zhu","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jiac.2017.08.008_bib14","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1111\/j.1600-0854.2011.01204.x","article-title":"Chlamydia trachomatis infection causes mitotic spindle pole defects independently from its effects on centrosome amplification","volume":"12","author":"Knowlton","year":"2011","journal-title":"Traffic"},{"key":"10.1016\/j.jiac.2017.08.008_bib15","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1111\/j.1462-5822.2009.01307.x","article-title":"Centrosome abnormalities during a Chlamydia trachomatis infection are caused by dysregulation of the normal duplication pathway","volume":"11","author":"Johnson","year":"2009","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.jiac.2017.08.008_bib16","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1111\/j.1600-0854.2006.00439.x","article-title":"Chlamydia trachomatis causes centrosomal defects resulting in chromosomal segregation abnormalities","volume":"7","author":"Grieshaber","year":"2006","journal-title":"Traffic"},{"key":"10.1016\/j.jiac.2017.08.008_bib17","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1158\/1055-9965.EPI-11-0116","article-title":"Age-stratified performance of the Cervista HPV 16\/18 genotyping test in women with ASC-US cytology","volume":"20","author":"Einstein","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jiac.2017.08.008_bib18","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/cncy.21240","article-title":"The role of human papillomavirus type 16\/18 genotyping in predicting high-grade cervical\/vaginal intraepithelial neoplasm in women with mildly abnormal Papanicolaou results","volume":"121","author":"Guo","year":"2013","journal-title":"Cancer Cytopathol"},{"key":"10.1016\/j.jiac.2017.08.008_bib19","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1159\/000325116","article-title":"High risk human papillomavirus DNA detection in pap tests with both atypical squamous cells of undetermined significance and Candida","volume":"53","author":"Hall","year":"2009","journal-title":"Acta Cytol"},{"key":"10.1016\/j.jiac.2017.08.008_bib20","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1016\/j.clinthera.2016.10.005","article-title":"Associations between vaginal infections and potential high-risk and high-risk human papillomavirus genotypes in female sex workers in western Kenya","volume":"38","author":"Menon","year":"2016","journal-title":"Clin Ther"},{"key":"10.1016\/j.jiac.2017.08.008_bib21","doi-asserted-by":"crossref","first-page":"240190","DOI":"10.5402\/2012\/240190","article-title":"Evaluation of association between vaginal infections and high-risk human papillomavirus types in female sex workers in Spain","volume":"2012","author":"Rodriguez-Cerdeira","year":"2012","journal-title":"ISRN Obstet Gynecol"},{"key":"10.1016\/j.jiac.2017.08.008_bib22","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2340\/00015555757578","article-title":"Human papilloma virus infection among women attending an STD clinic correlated to reason for attending, presence of clinical signs, concomitant infections and abnormal cytology","volume":"75","author":"Voog","year":"1995","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jiac.2017.08.008_bib23","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/jmv.1890430218","article-title":"Variability of polymerase chain reaction-based detection of human papillomavirus DNA is associated with the composition of vaginal microbial flora","volume":"43","author":"McNicol","year":"1994","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.jiac.2017.08.008_bib24","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1093\/aje\/kwi262","article-title":"Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents","volume":"162","author":"Samoff","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jiac.2017.08.008_bib25","first-page":"1371","article-title":"Association of human papillomavirus, Neisseria gonorrhoeae and Chlamydia trachomatis co-infections on the risk of high-grade squamous intraepithelial cervical lesion","volume":"6","author":"de Abreu","year":"2016","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.jiac.2017.08.008_bib26","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s40168-016-0203-0","article-title":"The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next?","volume":"4","author":"Mitra","year":"2016","journal-title":"Microbiome"},{"key":"10.1016\/j.jiac.2017.08.008_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153274","article-title":"Cervical microbiome and cytokine profile at various stages of cervical cancer: a pilot study","volume":"11","author":"Audirac-Chalifour","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jiac.2017.08.008_bib28","article-title":"Association of the vaginal microbiota with human papillomavirus infection in a Korean twin cohort","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jiac.2017.08.008_bib29","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1186\/s12879-017-2501-y","article-title":"Prevalence and distribution of Gardnerella vaginalis subgroups in women with and without bacterial vaginosis","volume":"17","author":"Janulaitiene","year":"2017","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jiac.2017.08.008_bib30","doi-asserted-by":"crossref","first-page":"3438","DOI":"10.1128\/IAI.00409-15","article-title":"Streptococcus salivarius K12 limits group B Streptococcus vaginal colonization","volume":"83","author":"Patras","year":"2015","journal-title":"Infect Immun"},{"key":"10.1016\/j.jiac.2017.08.008_bib31","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3389\/fimmu.2014.00519","article-title":"Interaction of Streptococcus agalactiae and cellular innate immunity in colonization and disease","volume":"5","author":"Landwehr-Kenzel","year":"2014","journal-title":"Front Immunol"},{"key":"10.1016\/j.jiac.2017.08.008_bib32","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s10096-016-2787-5","article-title":"Abnormal vaginal flora in symptomatic non-pregnant and pregnant women in a Greek hospital: a prospective study","volume":"36","author":"Tansarli","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jiac.2017.08.008_bib33","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1099\/00222615-45-2-120","article-title":"Bacterial vaginosis in pregnancy: distribution of bacterial species in different gram-stain categories of the vaginal flora","volume":"45","author":"Rosenstein","year":"1996","journal-title":"J\u00a0Med Microbiol"},{"key":"10.1016\/j.jiac.2017.08.008_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0181135","article-title":"The association between ethnicity and vaginal microbiota composition in Amsterdam, The Netherlands","volume":"12","author":"Borgdorff","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jiac.2017.08.008_bib35","first-page":"98","article-title":"Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria","volume":"14","author":"Numanovic","year":"2017","journal-title":"Med Glas (Zenica)"},{"key":"10.1016\/j.jiac.2017.08.008_bib36","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftw007","article-title":"Escherichia coli and Enterococcus faecalis are able to incorporate and enhance a pre-formed Gardnerella vaginalis biofilm","volume":"74","author":"Castro","year":"2016","journal-title":"Pathog Dis"},{"key":"10.1016\/j.jiac.2017.08.008_bib37","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.chom.2013.05.010","article-title":"Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response","volume":"13","author":"Chumduri","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jiac.2017.08.008_bib38","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1600-0897.2011.01041.x","article-title":"Characterization of gut-derived intraepithelial lymphocyte (IEL) residing in human papillomavirus (HPV)-infected intraepithelial neoplastic lesions","volume":"66","author":"Kojima","year":"2011","journal-title":"Am J Reprod Immunol"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X17301873?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X17301873?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:56:31Z","timestamp":1761159391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X17301873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":38,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S1341321X17301873"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2017.08.008","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of co-infection complicated with human papillomavirus on cervical intraepithelial neoplasia development in patients with atypical squamous cells of undetermined significance","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2017.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}