{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:51:16Z","timestamp":1779911476558,"version":"3.53.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.jiac.2018.03.007","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T12:02:24Z","timestamp":1522843344000},"page":"610-614","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis"],"prefix":"10.1016","volume":"24","author":[{"given":"Takashi","family":"Deguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Hatazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Horie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Nakane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Mizutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeaki","family":"Yokoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2018.03.007_bib1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/iju.13044","article-title":"Male non-gonococcal urethritis: from microbiological etiologies to demographic and clinical features","volume":"23","author":"Ito","year":"2016","journal-title":"Int J Urol"},{"key":"10.1016\/j.jiac.2018.03.007_bib2","first-page":"1210","article-title":"Mycoplasma genitalium: another important pathogen of nongonococcal urethritis","volume":"167","author":"Deguchi","year":"2002","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jiac.2018.03.007_bib3","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1093\/jac\/dku164","article-title":"Remarkable increase in fluoroquinolone-resistant Mycoplasma genitalium in Japan","volume":"69","author":"Kikuchi","year":"2014","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib4","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.jiac.2017.03.008","article-title":"Emergence of Mycoplasma genitalium with clinically significant fluoroquinolone resistance conferred by amino acid changes both in GyrA and ParC in Japan","volume":"23","author":"Deguchi","year":"2017","journal-title":"J\u00a0Infect Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib5","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/cid\/civ898","article-title":"Multidrug-resistant Mycoplasma genitalium is increasing","volume":"62","author":"Deguchi","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2018.03.007_bib6","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/infdis\/162.6.1309","article-title":"Partial characterization of Chlamydia trachomatis isolates resistant to multiple antibiotics","volume":"162","author":"Jones","year":"1990","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.jiac.2018.03.007_bib7","first-page":"376","article-title":"Tetracycline-resistant Chlamydia trachomatis in Toulouse, France","volume":"45","author":"Lefevre","year":"1997","journal-title":"Pathol Biol (Paris)"},{"key":"10.1016\/j.jiac.2018.03.007_bib8","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1086\/315372","article-title":"Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure","volume":"181","author":"Somani","year":"2000","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.jiac.2018.03.007_bib9","first-page":"3","article-title":"Analysis of point mutations in the ygeD, gyrA and parC genes in fluoroquinolones resistant clinical isolates of Chlamydia trachomatis","volume":"3","author":"Misiurina","year":"2004","journal-title":"Mol Gen Mikrobiol Virusol"},{"key":"10.1016\/j.jiac.2018.03.007_bib10","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1159\/000314998","article-title":"Decreased susceptibility to azithromycin and doxycycline in clinical isolates of Chlamydia trachomatis obtained from recurrently infected female patients in India","volume":"56","author":"Bhengraj","year":"2010","journal-title":"Chemotherapy"},{"key":"10.1016\/j.jiac.2018.03.007_bib11","doi-asserted-by":"crossref","first-page":"5379","DOI":"10.1128\/AAC.00553-10","article-title":"In\u00a0vitro activities of several antimicrobial agents against recently isolated and genotyped Chlamydia trachomatis urogenital serovars D through K","volume":"54","author":"Donati","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib12","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s12223-012-0218-2","article-title":"In\u00a0vitro susceptibility of urogenital Chlamydia trachomatis strains in a country with high azithromycin consumption rate","volume":"58","author":"Ljubin-Sternak","year":"2013","journal-title":"Folia Microbiol (Praha)"},{"key":"10.1016\/j.jiac.2018.03.007_bib13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/OLQ.0000000000000241","article-title":"Association of the in\u00a0vitro\u00a0susceptibility of clinical isolates of Chlamydia trachomatis with serovar and duration of antibiotic exposure","volume":"42","author":"Zheng","year":"2015","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.jiac.2018.03.007_bib14","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.jiac.2016.06.010","article-title":"Nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan","volume":"22","author":"Takahashi","year":"2016","journal-title":"J\u00a0Infect Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib15","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.jiac.2017.04.005","article-title":"Antimicrobial susceptibilities of Chlamydia trachomatis isolated from the urethra and pharynx of Japanese males","volume":"23","author":"Kai","year":"2017","journal-title":"J\u00a0Infect Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib16","doi-asserted-by":"crossref","first-page":"656","DOI":"10.2741\/4611","article-title":"Molecular mechanisms of Chlamydia trachomatis resistance to antimicrobial drugs","volume":"23","author":"Mestrovic","year":"2018","journal-title":"Front Biosci (Landmark Ed)"},{"key":"10.1016\/j.jiac.2018.03.007_bib17","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1128\/AAC.48.4.1347-1349.2004","article-title":"Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides","volume":"48","author":"Misyurina","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib18","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3892\/etm.2015.2595","article-title":"Differences in 23S ribosomal RNA mutations between wild-type and mutant macrolide-resistant Chlamydia trachomatis isolates","volume":"10","author":"Jiang","year":"2015","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.jiac.2018.03.007_bib19","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s10156-004-0332-4","article-title":"Uncommon occurrence of fluoroquinolone resistance-associated alterations in GyrA and ParC in clinical strains of Chlamydia trachomatis","volume":"10","author":"Yokoi","year":"2004","journal-title":"J\u00a0Infect Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib20","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/jac\/dkf031","article-title":"Serial passage of chlamydia spp. in sub-inhibitory fluoroquinolone concentrations","volume":"49","author":"Morrissey","year":"2002","journal-title":"J\u00a0Antimicrob Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib21","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1128\/AAC.42.10.2474","article-title":"Sequencing of gyrase and topoisomerase IV quinolone-resistance-determining regions of Chlamydia trachomatis and characterization of quinolone-resistant mutants obtained in\u00a0vitro","volume":"42","author":"Dessus-Babus","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jiac.2018.03.007_bib22","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1056\/NEJMoa1502599","article-title":"Azithromycin versus doxycycline for urogenital Chlamydia trachomatis Infection","volume":"373","author":"Geisler","year":"2015","journal-title":"N\u00a0Engl J Med"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X18300850?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X18300850?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:57:05Z","timestamp":1761159425000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X18300850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S1341321X18300850"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2018.03.007","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2018.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}