{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T07:18:24Z","timestamp":1773299904394,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.jiac.2019.04.008","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T09:24:25Z","timestamp":1557912265000},"page":"791-796","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Could platelet to leucocytic count ratio (PLR) predict sepsis and clinical outcomes in patients with emphysematous pyelonephritis?"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5669-2999","authenticated-orcid":false,"given":"M.A.","family":"Elbaset","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad H.","family":"Zahran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelwahab","family":"Hashem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fady K.","family":"Ghobrial","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Elrefaie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Badawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed A.","family":"Shokeir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Abdelbaset","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nrurol.2009.51","article-title":"Current management of emphysematous pyelonephritis","volume":"6","author":"Pontin","year":"2009","journal-title":"Nat Rev Urol"},{"issue":"3","key":"10.1016\/j.jiac.2019.04.008_bib2","first-page":"880","article-title":"Risk factors for mortality in patients with emphysematous pyelonephritis: a meta-analysis","volume":"178","author":"Falagas","year":"2007","journal-title":"J\u00a0Urol"},{"issue":"9","key":"10.1016\/j.jiac.2019.04.008_bib3","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1111\/j.1464-410X.2010.09660.x","article-title":"Emphysematous pyelonephritis","volume":"107","author":"Ubee","year":"2011","journal-title":"BJU Int"},{"issue":"4","key":"10.1016\/j.jiac.2019.04.008_bib4","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s11255-009-9552-y","article-title":"Retrospective analysis of clinical profile prognostic factors and outcomes of 19 patients of emphysematous pyelonephritis","volume":"41","author":"Khaira","year":"2009","journal-title":"Int Urol Nephrol"},{"issue":"7","key":"10.1016\/j.jiac.2019.04.008_bib5","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1097\/00003246-200107000-00002","article-title":"Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care","volume":"29","author":"Angus","year":"2001","journal-title":"Crit care med"},{"issue":"13","key":"10.1016\/j.jiac.2019.04.008_bib6","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1056\/NEJMoa0810625","article-title":"Intensive versus conventional glucose control in critically ill patients","volume":"360","author":"Investigators","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"16","key":"10.1016\/j.jiac.2019.04.008_bib7","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1056\/NEJMoa1310799","article-title":"Changes in diabetes-related complications in the United States, 1990\u20132010","volume":"370","author":"Gregg","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.jiac.2019.04.008_bib8","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0002-9343(02)01054-9","article-title":"Epidemiology of urinary tract infections: incidence, morbidity, and economic costs","volume":"113","author":"Foxman","year":"2002","journal-title":"Am J Med"},{"issue":"3","key":"10.1016\/j.jiac.2019.04.008_bib9","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00063110-200209000-00012","article-title":"Emphysematous pyelonephritis: no longer a surgical disease?","volume":"9","author":"Mallet","year":"2002","journal-title":"Eur J Emerg Med"},{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib10","first-page":"1844","article-title":"Is percutaneous drainage the new gold standard in the management of emphysematous pyelonephritis? Evidence from a systematic review","volume":"179","author":"Somani","year":"2008","journal-title":"J\u00a0Urol"},{"issue":"2","key":"10.1016\/j.jiac.2019.04.008_bib11","first-page":"369","article-title":"Predictors of outcome in emphysematous pyelonephritis","volume":"159","author":"Wan","year":"1998","journal-title":"J\u00a0Urol"},{"issue":"11","key":"10.1016\/j.jiac.2019.04.008_bib12","doi-asserted-by":"crossref","first-page":"E414","DOI":"10.5489\/cuaj.4478","article-title":"Platelet to white blood cell ratio predicts 30-day postoperative infectious complications in patients undergoing radical nephrectomy for renal malignancy","volume":"11","author":"Garbens","year":"2017","journal-title":"Can Urol Assoc J"},{"issue":"6","key":"10.1016\/j.jiac.2019.04.008_bib13","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1001\/archinte.160.6.797","article-title":"Emphysematous pyelonephritis: clinicoradiological classification, management, prognosis, and pathogenesis","volume":"160","author":"Huang","year":"2000","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.1016\/j.jiac.2019.04.008_bib14","first-page":"60","article-title":"Measurements of urinary bladder volume: comparison of five ultrasound calculation methods in volunteers","volume":"77","author":"Dicuio","year":"2005","journal-title":"Arch Ital Urol Androl \u2013 organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica"},{"issue":"8","key":"10.1016\/j.jiac.2019.04.008_bib15","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"Jama"},{"issue":"4","key":"10.1016\/j.jiac.2019.04.008_bib16","doi-asserted-by":"crossref","first-page":"266","DOI":"10.7326\/M17-2820","article-title":"Prognostic accuracy of the quick sequential organ failure assessment for mortality in patients with suspected infection: a systematic review and meta-analysis","volume":"168","author":"Fernando","year":"2018","journal-title":"Ann Intern Med"},{"issue":"11","key":"10.1016\/j.jiac.2019.04.008_bib17","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1016\/j.ajem.2017.07.001","article-title":"Comparison of QSOFA score and SIRS criteria as screening mechanisms for emergency department sepsis","volume":"35","author":"Haydar","year":"2017","journal-title":"Am J Emerg Med"},{"issue":"2","key":"10.1016\/j.jiac.2019.04.008_bib18","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1001\/jama.1995.03520260039030","article-title":"The natural history of the systemic inflammatory response syndrome (SIRS): a prospective study","volume":"273","author":"Rangel-Frausto","year":"1995","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib19","first-page":"477","article-title":"Systemic inflammatory response syndrome is an independent predictor of one-year mortality in patients with acute myocardial infarction","volume":"33","author":"Huang","year":"2017","journal-title":"Acta Cardiol Sin"},{"issue":"9","key":"10.1016\/j.jiac.2019.04.008_bib20","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1089\/10799900260286623","article-title":"Role of blood platelets in infection and inflammation","volume":"22","author":"Klinger","year":"2002","journal-title":"J\u00a0Interferon Cytokine Res"},{"issue":"9","key":"10.1016\/j.jiac.2019.04.008_bib21","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/BF03347372","article-title":"Oxidative stress in the metabolic syndrome","volume":"29","author":"Esposito","year":"2006","journal-title":"J\u00a0Endocrinol Investig"},{"key":"10.1016\/j.jiac.2019.04.008_bib22","article-title":"Markers of pro-inflammatory and pro-thrombotic state in the diagnosis of metabolic syndrome","volume":"52","author":"Odrow\u0105\u017c-Sypniewska","year":"2007","journal-title":"Adv Med Sci (De Gruyter Open)"},{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib23","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1097\/01.ta.0000189001.00670.d2","article-title":"White blood cell and platelet counts can be used to differentiate between infection and the normal response after splenectomy for trauma: prospective validation","volume":"59","author":"Weng","year":"2005","journal-title":"J\u00a0Trauma Acute Care Sur"},{"issue":"3","key":"10.1016\/j.jiac.2019.04.008_bib24","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1177\/0115426505020003314","article-title":"Albumin therapy in clinical practice","volume":"20","author":"Mendez","year":"2005","journal-title":"Nutr Clin Pract"},{"issue":"2","key":"10.1016\/j.jiac.2019.04.008_bib25","doi-asserted-by":"crossref","first-page":"e470","DOI":"10.1016\/S1569-9056(18)31173-4","article-title":"Clinical, biochemical and microbiological determinants in the clinical course of patients with emphysematous pyelonephritis: a case series of 43 patients in a single hospital in Mexico","volume":"17","author":"Lumbreras","year":"2018","journal-title":"Eur Urol Suppl"},{"issue":"1","key":"10.1016\/j.jiac.2019.04.008_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/(SICI)1096-9136(199701)14:1<29::AID-DIA300>3.0.CO;2-V","article-title":"Impaired leucocyte functions in diabetic patients","volume":"14","author":"Delamaire","year":"1997","journal-title":"Diabet Med"},{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.4103\/0019-5049.144666","article-title":"Disseminated intravascular coagulation","volume":"58","author":"Venugopal","year":"2014","journal-title":"Ind J Anaesth"},{"issue":"2","key":"10.1016\/j.jiac.2019.04.008_bib28","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1046\/j.1365-2141.1999.01553.x","article-title":"Circulating platelet\u2013neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing","volume":"106","author":"Peters","year":"1999","journal-title":"Br J Haematol"},{"issue":"11","key":"10.1016\/j.jiac.2019.04.008_bib29","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/j.1365-2362.1995.tb01694.x","article-title":"Platelet activation and interaction with leucocytes in patients with sepsis or multiple organ failure","volume":"25","author":"Gawaz","year":"1995","journal-title":"Eur J Clin Investig"},{"issue":"1","key":"10.1016\/j.jiac.2019.04.008_bib30","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4161\/viru.26982","article-title":"Gender differences in sepsis: cardiovascular and immunological aspects","volume":"5","author":"Angele","year":"2014","journal-title":"Virulence"},{"issue":"2","key":"10.1016\/j.jiac.2019.04.008_bib31","doi-asserted-by":"crossref","first-page":"R72","DOI":"10.1186\/cc12680","article-title":"Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study","volume":"17","author":"Arabi","year":"2013","journal-title":"Crit Care"},{"issue":"1\u20132","key":"10.1016\/j.jiac.2019.04.008_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00508-009-1241-4","article-title":"The association between body-mass index and patient outcome in septic shock: a retrospective cohort study","volume":"122","author":"Wurzinger","year":"2010","journal-title":"Wien Klin Wochenschr"},{"issue":"5","key":"10.1016\/j.jiac.2019.04.008_bib33","doi-asserted-by":"crossref","first-page":"774","DOI":"10.21037\/tau.2016.07.02","article-title":"Emphysematous pyelonephritis: the impact of urolithiasis on disease severity","volume":"5","author":"Sanford","year":"2016","journal-title":"Transl Androl Urol"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X1930100X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X1930100X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:58:34Z","timestamp":1761159514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X1930100X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S1341321X1930100X"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2019.04.008","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Could platelet to leucocytic count ratio (PLR) predict sepsis and clinical outcomes in patients with emphysematous pyelonephritis?","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2019.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}