{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:00:12Z","timestamp":1790251212498,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.jiac.2020.08.005","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T08:13:29Z","timestamp":1598602409000},"page":"32-39","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Several catechins and flavonols from green tea inhibit severe fever with thrombocytopenia syndrome virus infection in\u00a0vitro"],"prefix":"10.1016","volume":"27","author":[{"given":"Motohiko","family":"Ogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Shimojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Saijo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayoshi","family":"Fukasawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2020.08.005_bib1","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1128\/JCM.00742-14","article-title":"Sensitive and specific pcr systems for detection of both Chinese and Japanese severe fever with thrombocytopenia syndrome virus strains and prediction of patient survival based on viral load","volume":"52","author":"Yoshikawa","year":"2014","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.jiac.2020.08.005_bib2","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1056\/NEJMoa1010095","article-title":"Fever with thrombocytopenia associated with a novel bunyavirus in China","volume":"364","author":"Yu","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jiac.2020.08.005_bib3","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.3201\/eid1911.130792","article-title":"Severe fever with thrombocytopenia syndrome, South Korea, 2012","volume":"19","author":"Kim","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiac.2020.08.005_bib4","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/infdis\/jit603","article-title":"The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan","volume":"209","author":"Takahashi","year":"2014","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.jiac.2020.08.005_bib5","unstructured":"Infectious Diseases Weekly Report (IDWR). In: National Institute of Infectious Diseases. https:\/\/www.niid.go.jp\/niid\/ja\/idwr.html [Accessed 15 May 2020]."},{"key":"10.1016\/j.jiac.2020.08.005_bib6","doi-asserted-by":"crossref","first-page":"692","DOI":"10.3201\/eid2604.191011","article-title":"Severe fever with thrombocytopenia syndrome, Japan, 2013\u20132017","volume":"26","author":"Kobayashi","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiac.2020.08.005_bib7","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/0091-7435(92)90041-F","article-title":"Green tea composition, consumption, and polyphenol chemistry","volume":"21","author":"Graham","year":"1992","journal-title":"Prev Med"},{"key":"10.1016\/j.jiac.2020.08.005_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/162750","article-title":"Chemistry and biological activities of flavonoids: an overview","volume":"2013","author":"Kumar","year":"2013","journal-title":"Sci World J"},{"key":"10.1016\/j.jiac.2020.08.005_bib9","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ijantimicag.2011.02.014","article-title":"Recent advances in understanding the antibacterial properties of flavonoids","volume":"38","author":"Cushnie","year":"2011","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jiac.2020.08.005_bib10","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.micres.2009.09.002","article-title":"Antibacterial, antifungal, and antiviral activities of some flavonoids","volume":"165","author":"Orhan","year":"2010","journal-title":"Microbiol Res"},{"key":"10.1016\/j.jiac.2020.08.005_bib11","article-title":"Efficacy of T-705 (favipiravir) in the treatment of infections with lethal severe fever with thrombocytopenia syndrome virus","volume":"1","author":"Tani","year":"2010","journal-title":"mSphere"},{"key":"10.1016\/j.jiac.2020.08.005_bib12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.7883\/yoken.JJID.2014.231","article-title":"Isolation and characterization of an Huh.7.5.1-derived cell clone highly permissive to hepatitis C virus","volume":"68","author":"Shirasago","year":"2014","journal-title":"Jpn J Infect Dis"},{"key":"10.1016\/j.jiac.2020.08.005_bib13","doi-asserted-by":"crossref","first-page":"9294","DOI":"10.1073\/pnas.0503596102","article-title":"Robust hepatitis C virus infection in\u00a0vitro","volume":"102","author":"Zhong","year":"2005","journal-title":"Proc Natl Acad Sci Unit States Am"},{"key":"10.1016\/j.jiac.2020.08.005_bib14","doi-asserted-by":"crossref","first-page":"423","DOI":"10.7883\/yoken.67.423","article-title":"Effects of ribavirin on severe fever with thrombocytopenia syndrome virus in\u00a0vitro","volume":"67","author":"Shimojima","year":"2014","journal-title":"Jpn J Infect Dis"},{"key":"10.1016\/j.jiac.2020.08.005_bib15","first-page":"480","article-title":"Zur kollektiven behandlung pharmakologischer reihenversuche","volume":"162","author":"Beitrag","year":"1931","journal-title":"Archiv f\u00fcr Experimentelle Pathologie und Pharmakologie"},{"key":"10.1016\/j.jiac.2020.08.005_bib16","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.jiac.2018.03.005","article-title":"Caffeic acid, a coffee-related organic acid, inhibits infection by severe fever with thrombocytopenia syndrome virus in\u00a0vitro","volume":"24","author":"Ogawa","year":"2018","journal-title":"J\u00a0Infect Chemother"},{"key":"10.1016\/j.jiac.2020.08.005_bib17","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1128\/JCM.01931-12","article-title":"Detection of severe fever with thrombocytopenia syndrome virus by reverse transcription-cross-priming amplification coupled with vertical flow visualization","volume":"50","author":"Cui","year":"2012","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.jiac.2020.08.005_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/molecules22081337","article-title":"A\u00a0review of the antiviral role of green tea catechins","volume":"22","author":"Xu","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.jiac.2020.08.005_bib19","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jfca.2004.05.006","article-title":"Major flavonoids in dry tea","volume":"18","author":"Peterson","year":"2005","journal-title":"J\u00a0Food Compos Anal"},{"key":"10.1016\/j.jiac.2020.08.005_bib20","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1017\/S0007114510002709","article-title":"Plasma appearance and correlation between coffee and green tea metabolites in human subjects","volume":"104","author":"Renouf","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1016\/j.jiac.2020.08.005_bib21","first-page":"351","article-title":"Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers","volume":"7","author":"Yang","year":"1998","journal-title":"Cancer Epidemiol Biomark Prev"},{"key":"10.1016\/j.jiac.2020.08.005_bib22","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1158\/1078-0432.CCR-04-2549","article-title":"Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of polyphenon E in healthy individuals","volume":"11","author":"Chow","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jiac.2020.08.005_bib23","first-page":"105","article-title":"Pharmacokinetic and chemoprevention studies on tea in humans","volume":"64","author":"Chow","year":"2011","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.jiac.2020.08.005_bib24","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1248\/bpb.b18-00970","article-title":"Inhibition mechanisms of hepatitis C virus infection by caffeic acid and tannic acid","volume":"42","author":"Shirasago","year":"2019","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.jiac.2020.08.005_bib25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.fitote.2013.12.011","article-title":"Comparison of in\u00a0vitro antiviral activity of tea polyphenols against influenza A and B viruses and structure-activity relationship analysis","volume":"93","author":"Yang","year":"2014","journal-title":"Fitoterapia"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X20302750?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X20302750?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T19:01:14Z","timestamp":1761159674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X20302750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S1341321X20302750"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2020.08.005","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Several catechins and flavonols from green tea inhibit severe fever with thrombocytopenia syndrome virus infection in\u00a0vitro","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2020.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}