{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:33:10Z","timestamp":1793406790748,"version":"4.5.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T00:00:00Z","timestamp":1637452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["20HB1003"],"award-info":[{"award-number":["20HB1003"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H26-AIDS-006"],"award-info":[{"award-number":["H26-AIDS-006"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H29-AIDS-007"],"award-info":[{"award-number":["H29-AIDS-007"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.jiac.2021.11.012","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T01:18:51Z","timestamp":1637630331000},"page":"444-450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Clinical perspectives of Treponema pallidum subsp. Endemicum infection in adults, particularly men who have sex with men in the Kansai area, Japan: A case series"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8934-0375","authenticated-orcid":false,"given":"Koh","family":"Shinohara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8786-583X","authenticated-orcid":false,"given":"Keiichi","family":"Furubayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruyo","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Komano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-4188","authenticated-orcid":false,"given":"Takuya","family":"Kawahata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2021.11.012_bib1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1128\/CMR.00070-13","article-title":"The endemic treponematoses","volume":"27","author":"Giacani","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jiac.2021.11.012_bib2","series-title":"Mandell, Douglas, and Bennett's principles and practice of infectious diseases","first-page":"2893","article-title":"Endemic treponematoses","author":"Ahmed","year":"2020"},{"key":"10.1016\/j.jiac.2021.11.012_bib3","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/OLQ.0000000000000006","article-title":"Molecular subtyping of Treponema pallidum in paris, France","volume":"40","author":"Grange","year":"2013","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib4","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/OLQ.0000000000000474","article-title":"Treponema pallidum 11qj subtype may correspond to a Treponema pallidum subsp. Endemicum strain","volume":"43","author":"Grange","year":"2016","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib5","doi-asserted-by":"crossref","first-page":"1210.e1","DOI":"10.1016\/j.cmi.2018.02.006","article-title":"Bejel in Cuba: molecular identification of Treponema pallidum subsp. Endemicum in patients diagnosed with venereal syphilis","volume":"24","author":"Noda","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jiac.2021.11.012_bib6","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.3201\/eid2508.181690","article-title":"Bejel, a nonvenereal treponematosis, among men who have sex with men, Japan","volume":"25","author":"Kawahata","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib7","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01148-18","article-title":"Circulation of distinct Treponema pallidum strains in individuals with heterosexual orientation and men who had sex with men","volume":"57","author":"Kojima","year":"2019","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jiac.2021.11.012_bib8","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/tropej\/41.2.117","article-title":"Bejel in Malatya, Turkey","volume":"41","author":"Yakinci","year":"1995","journal-title":"J Trop Pediatr"},{"key":"10.1016\/j.jiac.2021.11.012_bib9","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.3201\/eid1806.111421","article-title":"Local transmission of imported endemic syphilis, Canada, 2011","volume":"18","author":"Fanella","year":"2012","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib10","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3201\/eid1901.120756","article-title":"A case of endemic syphilis, Iran","volume":"19","author":"Abdolrasouli","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.clindermatol.2005.11.004","article-title":"Endemic treponematosis: review and update","volume":"24","author":"Farnsworth","year":"2006","journal-title":"Clin Dematol"},{"key":"10.1016\/j.jiac.2021.11.012_bib12","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.clindermatol.2013.08.006","article-title":"Endemic syphilis in Europe","volume":"32","author":"Lipozen\u010di\u0107","year":"2014","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.jiac.2021.11.012_bib13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0035-9203(37)90099-3","article-title":"Bejel: the endemic syphilis of the Euphrates Arab","volume":"31","author":"Hudson","year":"1937","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.jiac.2021.11.012_bib14","first-page":"115","article-title":"Is bejel syphilis?","volume":"25","author":"Akrawi","year":"1949","journal-title":"Br J Vener Dis"},{"key":"10.1016\/j.jiac.2021.11.012_bib15","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1056\/NEJMoa040216","article-title":"Macrolide resistance in Treponema pallidum in the United States and Ireland","volume":"351","author":"Lukehart","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jiac.2021.11.012_bib16","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1099\/jmm.0.007542-0","article-title":"Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp","volume":"58","author":"Mat\u011bjkov\u00e1","year":"2009","journal-title":"Pallidum J Med Microbiol"},{"key":"10.1016\/j.jiac.2021.11.012_bib17","doi-asserted-by":"crossref","first-page":"678","DOI":"10.4269\/ajtmh.15-0316","article-title":"Macrolide resistance in the syphilis spirochete, Treponema pallidum ssp. pallidum: Can we also expect macrolide-resistant yaws strains?","volume":"94","author":"\u0160majs","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.jiac.2021.11.012_bib18","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/S0140-6736(18)30204-6","article-title":"Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study","volume":"391","author":"Mitj\u00e0","year":"2018","journal-title":"Lancet"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X21003238?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X21003238?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T19:03:48Z","timestamp":1761159828000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X21003238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S1341321X21003238"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2021.11.012","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical perspectives of Treponema pallidum subsp. Endemicum infection in adults, particularly men who have sex with men in the Kansai area, Japan: A case series","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2021.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}