{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:43:06Z","timestamp":1792068186886,"version":"4.4.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jiac-j.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jiac.2025.102630","type":"journal-article","created":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T16:06:27Z","timestamp":1737821187000},"page":"102630","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["A fatal case of enterovirus A71-induced meningoencephalitis following allogenic hematopoietic stem cell transplantation"],"prefix":"10.1016","volume":"31","author":[{"given":"Yayoi","family":"Ueda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7892-4674","authenticated-orcid":false,"given":"Hiroki","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5086-1891","authenticated-orcid":false,"given":"Hideharu","family":"Hagiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risa","family":"Hashida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saya","family":"Kubota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mami","family":"Takemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0092-1339","authenticated-orcid":false,"given":"Kenta","family":"Hayashino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8676-0825","authenticated-orcid":false,"given":"Tomohiro","family":"Nagano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuichiro","family":"Hiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7614-2448","authenticated-orcid":false,"given":"Keiko","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6395-7913","authenticated-orcid":false,"given":"Takumi","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Seike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noboru","family":"Asada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Ennishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuharu","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maeda","family":"Yoshinobu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2025.102630_bib1","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1128\/JCM.00730-16","article-title":"Multicenter evaluation of BioFire FilmArray meningitis\/encephalitis panel for detection of bacteria, viruses, and Yeast in cerebrospinal fluid Specimens","volume":"54","author":"Leber","year":"2016","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jiac.2025.102630_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20205201","article-title":"Enterovirus-associated hand-foot and mouth disease and neurological complications in Japan and the rest of the World","volume":"20","author":"Gonzalez","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jiac.2025.102630_bib3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12929-019-0573-2","article-title":"The history of enterovirus A71 outbreaks and Molecular Epidemiology in the Asia-Pacific region","volume":"26","author":"Puenpa","year":"2019","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.jiac.2025.102630_bib4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1086\/318454","article-title":"Neurological manifestations of enterovirus 71 infection in children during an outbreak of hand, foot, and mouth disease in Western Australia","volume":"32","author":"McMinn","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2025.102630_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s12929-019-0552-7","article-title":"Enterovirus A71 neurologic complications and long-term sequelae","volume":"26","author":"Chang","year":"2019","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.jiac.2025.102630_bib6","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1212\/WNL.0000000000004148","article-title":"Enteroviral T-cell encephalitis related to immunosuppressive therapy including rituximab","volume":"89","author":"Garzo-Caldas","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.jiac.2025.102630_bib7","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1093\/annonc\/mdw155","article-title":"CNS infections in patients with hematological disorders (including allogeneic stem-cell transplantation)-Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)","volume":"27","author":"Schmidt-Hieber","year":"2016","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jiac.2025.102630_bib8","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.bbmt.2016.10.005","article-title":"Infections of the central nervous system after unrelated donor Umbilical cord blood transplantation or human leukocyte antigen-matched Sibling transplantation","volume":"23","author":"Balaguer Rosello","year":"2017","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jiac.2025.102630_bib9","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1038\/s41409-019-0457-9","article-title":"Virus detection in the cerebrospinal fluid of hematopoietic stem cell transplant recipients is associated with poor patient outcomes: a CIBMTR contemporary longitudinal study","volume":"54","author":"Abidi","year":"2019","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.jiac.2025.102630_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.27448","article-title":"Enterovirus infections in pediatric hematologic\/oncologic patients","volume":"66","author":"Strenger","year":"2019","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jiac.2025.102630_bib11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1080\/08880010050034337","article-title":"Enteroviral meningoencephalitis in immunocompromised children after matched unrelated donor-bone marrow transplantation","volume":"17","author":"Fischmeister","year":"2000","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.jiac.2025.102630_bib12","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/pbc.20384","article-title":"Outcome of CNS and pulmonary enteroviral infections after hematopoietic cell transplantation","volume":"45","author":"Tan","year":"2005","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jiac.2025.102630_bib13","first-page":"1","article-title":"Prevention. Enterovirus surveillance--United States, 1970-2005","volume":"55","author":"Khetsuriani","year":"2006","journal-title":"MMWR Surveill Summ"},{"key":"10.1016\/j.jiac.2025.102630_bib14","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3324\/haematol.2016.144428","article-title":"Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines","volume":"101","author":"Styczynski","year":"2016","journal-title":"Haematologica"},{"key":"10.1016\/j.jiac.2025.102630_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11910-021-01119-w","article-title":"Central nervous system infections in immunocompromised patients","volume":"21","author":"Pruitt","year":"2021","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.jiac.2025.102630_bib16","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ejpn.2013.03.004","article-title":"MRI characteristics of brainstem encephalitis in hand-foot-mouth disease induced by enterovirus type 71--will different MRI manifestations be helpful for prognosis?","volume":"17","author":"Chen","year":"2013","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.jiac.2025.102630_bib17","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1056\/NEJM199909233411302","article-title":"Neurologic complications in children with enterovirus 71 infection","volume":"341","author":"Huang","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jiac.2025.102630_bib18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00520-021-06474-5","article-title":"Usefulness of the FilmArray Meningitis\/Encephalitis Panel in diagnosis of central nervous system infection after allogeneic hematopoietic stem cell transplantation","volume":"30","author":"Mori","year":"2022","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.jiac.2025.102630_bib19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1365-2257.2006.00751.x","article-title":"Enteroviral meningoencephalitis in a patient with non-Hodgkin's lymphoma treated previously with rituximab","volume":"28","author":"Padate","year":"2006","journal-title":"Clin Lab Haematol"},{"key":"10.1016\/j.jiac.2025.102630_bib20","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/MPH.0b013e3180f61bbc","article-title":"Enterovirus 71 meningoencephalitis during chemotherapy in a child with metastatic osteosarcoma","volume":"29","author":"Frange","year":"2007","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.jiac.2025.102630_bib21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijid.2021.10.002","article-title":"Characteristics and therapy of enteroviral encephalitis: case report and systematic literature review","volume":"113","author":"Wagner","year":"2021","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.jiac.2025.102630_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneuroim.2021.577639","article-title":"Enterovirus A71 causing meningoencephalitis and acute flaccid myelitis in a patient receiving rituximab","volume":"358","author":"Kapadia","year":"2021","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.jiac.2025.102630_bib23","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1038\/emi.2016.73","article-title":"EV-A71 vaccine licensure: a first step for multivalent enterovirus vaccine to control HFMD and other severe diseases","volume":"5","author":"Mao","year":"2016","journal-title":"Emerg Microbes Infect"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25000261?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25000261?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T02:15:34Z","timestamp":1744424134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X25000261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S1341321X25000261"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102630","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A fatal case of enterovirus A71-induced meningoencephalitis following allogenic hematopoietic stem cell transplantation","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102630","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102630"}}