{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:40:04Z","timestamp":1791823204915,"version":"4.3.4"},"reference-count":42,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.jiac.2025.102729","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:49:37Z","timestamp":1747151377000},"page":"102729","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Does the use of pulsed-xenon ultraviolet light reduce the risk of healthcare-associated infections?: An updated systematic review and meta-analysis"],"prefix":"10.1016","volume":"31","author":[{"given":"Lejuan","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chungen","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jvmei","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2025.102729_bib1","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.2147\/IDR.S177247","article-title":"Health care-associated infections - an overview","volume":"11","author":"Haque","year":"2018","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jiac.2025.102729_bib2","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2018.23.46.1800516","article-title":"Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017","volume":"23","author":"Suetens","year":"2018","journal-title":"Euro Surveill"},{"key":"10.1016\/j.jiac.2025.102729_bib3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1017\/ice.2018.60","article-title":"The prevalence of healthcare-associated infections in mainland China: a systematic review and meta-analysis","volume":"39","author":"Wang","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0274248","article-title":"Global prevalence of nosocomial infection: a systematic review and meta-analysis","volume":"18","author":"Raoofi","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.jiac.2025.102729_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jhin.2021.03.031","article-title":"Epidemiology of healthcare-associated infection reported from a hospital-wide incidence study: considerations for infection prevention and control planning","volume":"114","author":"Stewart","year":"2021","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jiac.2025.102729_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1586\/erp.09.53","article-title":"Economic burden of healthcare-associated infections: an American perspective","volume":"9","author":"Stone","year":"2009","journal-title":"Expert Rev Pharmacoecon Outcomes Res"},{"key":"10.1016\/j.jiac.2025.102729_bib7","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.2147\/RMHP.S269315","article-title":"Strategies to prevent healthcare-associated infections: a narrative overview","volume":"13","author":"Haque","year":"2020","journal-title":"Risk Manag Healthc Policy"},{"key":"10.1016\/j.jiac.2025.102729_bib8","doi-asserted-by":"crossref","first-page":"598","DOI":"10.7326\/M15-1192","article-title":"Cleaning hospital room surfaces to prevent health care-associated infections: a technical brief","volume":"163","author":"Han","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jiac.2025.102729_bib9","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1086\/591940","article-title":"Improving cleaning of the environment surrounding patients in 36 acute care hospitals","volume":"29","author":"Carling","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib10","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1001\/archinternmed.2011.64","article-title":"Environmental cleaning intervention and risk of acquiring multidrug-resistant organisms from prior room occupants","volume":"171","author":"Datta","year":"2011","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jiac.2025.102729_bib11","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1086\/670217","article-title":"An environmental disinfection odyssey: evaluation of sequential interventions to improve disinfection of Clostridium difficile isolation rooms","volume":"34","author":"Sitzlar","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1017\/ice.2017.226","article-title":"No-touch disinfection methods to decrease multidrug-resistant organism infections: a systematic review and meta-analysis","volume":"39","author":"Marra","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib13","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1017\/ice.2014.36","article-title":"Evaluation of a pulsed xenon ultraviolet disinfection system for reduction of healthcare-associated pathogens in hospital rooms","volume":"36","author":"Nerandzic","year":"2015","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib14","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph192113780","article-title":"Pulsed-xenon ultraviolet light highly inactivates human coronaviruses on solid surfaces, particularly SARS-CoV-2","volume":"19","author":"Bello-Perez","year":"2022","journal-title":"Int J Environ Res Publ Health"},{"key":"10.1016\/j.jiac.2025.102729_bib15","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.ajic.2020.12.005","article-title":"Effect of pulsed-xenon ultraviolet light on environmental contamination and risk of health care worker hand contamination","volume":"49","author":"Montgomery","year":"2021","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib16","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/j.jiac.2021.08.011","article-title":"The effect of pulsed-xenon ultraviolet disinfection on surfaces contaminated with vancomycin-resistant Enterococci in a Japanese hospital","volume":"27","author":"Kitagawa","year":"2021","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.jiac.2025.102729_bib17","doi-asserted-by":"crossref","DOI":"10.1017\/S095026882000148X","article-title":"Role of pulsed-xenon ultraviolet light in reducing healthcare-associated infections: a systematic review and meta-analysis","volume":"148","author":"Dong","year":"2020","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.jiac.2025.102729_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.jiac.2025.102729_bib19","series-title":"Cochrane Handbook for systematic reviews of interventions","author":"Higgins","year":"2019"},{"key":"10.1016\/j.jiac.2025.102729_bib20","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jclinepi.2012.09.016","article-title":"Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity","volume":"66","author":"Kim","year":"2013","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib21","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.ajic.2013.02.010","article-title":"The effect of portable pulsed xenon ultraviolet light after terminal cleaning on hospital-associated Clostridium difficile infection in a community hospital","volume":"41","author":"Levin","year":"2013","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib22","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.ajic.2013.12.013","article-title":"Implementation and impact of ultraviolet environmental disinfection in an acute care setting","volume":"42","author":"Haas","year":"2014","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib23","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12879-020-4805-6","article-title":"Clinical and microbiological effect of pulsed xenon ultraviolet disinfection to reduce multidrug-resistant organisms in the intensive care unit in a Japanese hospital: a before-after study","volume":"20","author":"Morikane","year":"2020","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jiac.2025.102729_bib24","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.ajic.2021.01.019","article-title":"Combining pulsed xenon ultraviolet disinfection with terminal manual cleaning helps reduce the acquisition rate of methicillin-resistant Staphylococcus aureus","volume":"49","author":"Kitagawa","year":"2021","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib25","first-page":"1024","article-title":"Lowering the acquisition of multidrug-resistant organisms (MDROs) with pulsed-xenon (LAMP) study: a cluster-randomized, controlled, double-blinded, interventional crossover trial","volume":"79","author":"Dhar","year":"2024","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2025.102729_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jhin.2024.11.015","article-title":"Clinical and microbiological effectiveness of pulsed-xenon ultraviolet light disinfection in a neonatal intensive care unit in Japan","volume":"156","author":"Komamizu","year":"2025","journal-title":"J Hosp Infect"},{"key":"10.1016\/j.jiac.2025.102729_bib27","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.ajic.2015.07.029","article-title":"Utilization and impact of a pulsed-xenon ultraviolet room disinfection system and multidisciplinary care team on Clostridium difficile in a long-term acute care facility","volume":"43","author":"Miller","year":"2015","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib28","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.1016\/j.ajic.2015.12.018","article-title":"Influence of pulsed-xenon ultraviolet light-based environmental disinfection on surgical site infections","volume":"44","author":"Catalanotti","year":"2016","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib29","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ajic.2015.10.009","article-title":"Impact of pulsed xenon ultraviolet light on hospital-acquired infection rates in a community hospital","volume":"44","author":"Vianna","year":"2016","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib30","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.burns.2016.08.027","article-title":"Pulsed-xenon ultraviolet light disinfection in a burn unit: impact on environmental bioburden, multidrug-resistant organism acquisition and healthcare associated infections","volume":"43","author":"Green","year":"2017","journal-title":"Burns"},{"key":"10.1016\/j.jiac.2025.102729_bib31","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-017-2275-2","article-title":"Evaluation of an ultraviolet room disinfection protocol to decrease nursing home microbial burden, infection and hospitalization rates","volume":"17","author":"Kovach","year":"2017","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jiac.2025.102729_bib32","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1017\/ice.2018.215","article-title":"Effectiveness of ultraviolet disinfection in reducing hospital-acquired Clostridium difficile and vancomycin-resistant Enterococcus on a bone marrow transplant unit","volume":"39","author":"Brite","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jiac.2025.102729_bib33","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.ajic.2018.09.018","article-title":"A trial of pulsed xenon ultraviolet disinfection to reduce Clostridioides difficile infection","volume":"47","author":"Sampathkumar","year":"2019","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib34","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.ajic.2019.12.019","article-title":"The effect of pulsed xenon ultraviolet light disinfection on healthcare-associated Clostridioides difficile rates in a tertiary care hospital","volume":"48","author":"Attia","year":"2020","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib35","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1086\/527394","article-title":"Prior environmental contamination increases the risk of acquisition of vancomycin-resistant enterococci","volume":"46","author":"Drees","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2025.102729_bib36","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ajic.2019.08.033","article-title":"Effect of pulsed xenon ultraviolet disinfection on methicillin-resistant Staphylococcus aureus contamination of high-touch surfaces in a Japanese hospital","volume":"48","author":"Kitagawa","year":"2020","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ajic.2020.05.032","article-title":"Effectiveness of pulsed xenon ultraviolet disinfection for Clostridioides (Clostridium) difficile surface contamination in a Japanese hospital","volume":"49","author":"Kitagawa","year":"2021","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jiac.2025.102729_bib38","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1186\/s12879-019-4200-3","article-title":"Efficacy of pulsed-xenon ultraviolet light for disinfection of high-touch surfaces in an Ecuadorian hospital","volume":"19","author":"Villac\u00eds","year":"2019","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jiac.2025.102729_bib39","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.ajic.2018.02.027","article-title":"Environmental effectiveness of pulsed-xenon light in the operating room","volume":"46","author":"Simmons","year":"2018","journal-title":"Am J Infect Control"},{"issue":"Pt 2","key":"10.1016\/j.jiac.2025.102729_bib40","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1099\/jmm.0.000004","article-title":"Non-inferiority of pulsed xenon UV light versus bleach for reducing environmental Clostridium difficile contamination on high-touch surfaces in Clostridium difficile infection isolation rooms","volume":"64","author":"Ghantoji","year":"2015","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.jiac.2025.102729_bib41","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0140-6736(16)31588-4","article-title":"Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study","volume":"389","author":"Anderson","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jiac.2025.102729_bib42","doi-asserted-by":"crossref","first-page":"461.e7","DOI":"10.1016\/j.cmi.2016.01.010","article-title":"Hospitalization in double-occupancy rooms and the risk of hospital-acquired influenza: a prospective cohort study","volume":"22","author":"Munier-Marion","year":"2016","journal-title":"Clin Microbiol Infect"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25001266?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25001266?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T07:03:21Z","timestamp":1749711801000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X25001266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":42,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S1341321X25001266"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102729","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does the use of pulsed-xenon ultraviolet light reduce the risk of healthcare-associated infections?: An updated systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102729","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102729"}}