{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T10:06:30Z","timestamp":1764324390117,"version":"3.46.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP25fk0108699"],"award-info":[{"award-number":["JP25fk0108699"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jiac.2025.102845","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T02:41:53Z","timestamp":1761619313000},"page":"102845","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Whole-genome sequencing and in vitro characterization of a disseminated ST398 Staphylococcus aureus infection: A case report"],"prefix":"10.1016","volume":"31","author":[{"given":"Yosuke","family":"Sazumi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinnosuke","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5086-1891","authenticated-orcid":false,"given":"Hideharu","family":"Hagiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuhito","family":"Suyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9020-6118","authenticated-orcid":false,"given":"Kohei","family":"Oguni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyoshi","family":"Gotoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoko","family":"Kutsuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9330-4203","authenticated-orcid":false,"given":"Junzo","family":"Hisatsune","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoyuki","family":"Sugai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuma","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Iio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-9095","authenticated-orcid":false,"given":"Fumio","family":"Otsuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jiac.2025.102845_bib1","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1080\/21505594.2021.1878688","article-title":"Pathogenicity and virulence of Staphylococcus aureus","volume":"12","author":"Cheung","year":"2021","journal-title":"Virulence"},{"issue":"4","key":"10.1016\/j.jiac.2025.102845_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41579-018-0147-4","article-title":"Methicillin-resistant staphylococcus aureus: an overview of basic and clinical research","volume":"17","author":"Turner","year":"2019","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jiac.2025.102845_bib3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jgar.2021.03.030","article-title":"Staphylococcus aureus clones causing osteomyelitis: a literature review (2000-2020)","volume":"26","author":"Pimentel de Araujo","year":"2021","journal-title":"J Glob Antimicrob Resist"},{"issue":"2","key":"10.1016\/j.jiac.2025.102845_bib4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1164\/rccm.201506-1225LE","article-title":"Key role of alpha-toxin in fatal pneumonia caused by Staphylococcus aureus sequence type 398","volume":"193","author":"Bonesso","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"10.1016\/j.jiac.2025.102845_bib5","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.3390\/microorganisms8111737","article-title":"Human infection of methicillin-susceptible Staphylococcus aureus CC398: a review","volume":"8","author":"Bouiller","year":"2020","journal-title":"Microorganisms"},{"issue":"3\u20134","key":"10.1016\/j.jiac.2025.102845_bib6","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.vetmic.2007.01.027","article-title":"High prevalence of methicillin resistant Staphylococcus aureus in pigs","volume":"122","author":"de Neeling","year":"2007","journal-title":"Vet Microbiol"},{"issue":"9","key":"10.1016\/j.jiac.2025.102845_bib7","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1292\/jvms.22-0084","article-title":"First isolation of ST398 methicillin-resistant Staphylococcus aureus carrying staphylococcal cassette chromosome mec type IVd from pig ears in Japan","volume":"84","author":"Sasaki","year":"2022","journal-title":"J Vet Med Sci"},{"issue":"9","key":"10.1016\/j.jiac.2025.102845_bib8","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1292\/jvms.20-0184","article-title":"Isolation of ST398 methicillin-resistant Staphylococcus aureus from pigs at abattoirs in tohoku region, Japan","volume":"82","author":"Sasaki","year":"2020","journal-title":"J Vet Med Sci"},{"issue":"11","key":"10.1016\/j.jiac.2025.102845_bib9","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.3390\/microorganisms10112117","article-title":"Characterization of Staphylococcus aureus isolates from bovine mastitis and bulk tank milk: first isolation of methicillin-Susceptible Staphylococcus aureus in Japan","volume":"10","author":"Miyazawa","year":"2022","journal-title":"Microorganisms"},{"issue":"7","key":"10.1016\/j.jiac.2025.102845_bib10","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jiac.2015.03.013","article-title":"A fatal infection caused by sequence type 398 methicillin-resistant Staphylococcus aureus carrying the Panton-valentine leukocidin gene: a case report in Japan","volume":"21","author":"Koyama","year":"2015","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.jiac.2025.102845_bib11","article-title":"Genomic epidemiology and characterization of Staphylococcus aureus isolates from raw milk in Jiangsu, China: emerging broader host tropism strain clones ST59 and ST398","volume":"14","author":"Liu","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jiac.2025.102845_bib12","article-title":"Genetic variability in Neisseria meningitidis strains isolated in a Japanese hospital","volume":"14","author":"Gotoh","year":"2025","journal-title":"IJID Reg"},{"issue":"D1","key":"10.1016\/j.jiac.2025.102845_bib13","doi-asserted-by":"crossref","first-page":"D694","DOI":"10.1093\/nar\/gkv1239","article-title":"Vfdb 2016: hierarchical and refined dataset for big data analysis--10 years on","volume":"44","author":"Chen","year":"2016","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"10.1016\/j.jiac.2025.102845_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.05239-22","article-title":"Comprehensive genomic characterization of Staphylococcus aureus isolated from atopic dermatitis patients in Japan: correlations with disease severity, eruption type, and anatomical site","volume":"11","author":"Obata","year":"2023","journal-title":"Microbiol Spectr"},{"issue":"6","key":"10.1016\/j.jiac.2025.102845_bib15","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1093\/bioinformatics\/btx713","article-title":"DFAST: a flexible prokaryotic genome annotation pipeline for faster genome publication","volume":"34","author":"Tanizawa","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jiac.2025.102845_bib16","article-title":"SKA: split kmer analysis toolkit for bacterial genomic epidemiology","author":"Harris","year":"2018","journal-title":"bioRxiv"},{"issue":"3","key":"10.1016\/j.jiac.2025.102845_bib17","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1128\/JB.186.3.722-729.2004","article-title":"Control of glucose- and NaCl-induced biofilm formation by rbf in Staphylococcus aureus","volume":"186","author":"Lim","year":"2004","journal-title":"J Bacteriol"},{"issue":"5","key":"10.1016\/j.jiac.2025.102845_bib18","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1128\/iai.56.5.1061-1065.1988","article-title":"Variation in the expression of cell wall proteins of Staphylococcus aureus grown on solid and liquid media","volume":"56","author":"Cheung","year":"1988","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.jiac.2025.102845_bib19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3390\/pathogens4020210","article-title":"Pathogenicity of isolates of Serratia marcescens towards larvae of the scarab Phyllophaga blanchardi (coleoptera)","volume":"4","author":"Pineda-Castellanos","year":"2015","journal-title":"Pathogens"},{"key":"10.1016\/j.jiac.2025.102845_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2009\/614371","article-title":"Genotypic and phenotypic assessment of hyaluronidase among type strains of a Select Group of staphylococcal species","author":"Hart","year":"2009","journal-title":"Internet J Microbiol"},{"issue":"15","key":"10.1016\/j.jiac.2025.102845_bib21","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1001\/jama.298.15.1763","article-title":"Invasive methicillin-resistant Staphylococcus aureus infections in the United States","volume":"298","author":"Klevens","year":"2007","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.jiac.2025.102845_bib22","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/1469-0691.12718","article-title":"New epidemiology of Staphylococcus aureus infections","volume":"20","author":"Rasigade","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"12","key":"10.1016\/j.jiac.2025.102845_bib23","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.3201\/eid1112.050428","article-title":"Methicillin-resistant Staphylococcus aureus in pig farming","volume":"11","author":"Voss","year":"2005","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"10.1016\/j.jiac.2025.102845_bib24","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.3390\/pathogens11101110","article-title":"MRSA in humans, pets and livestock in Portugal: where we came from and where we are going","volume":"11","author":"Silva","year":"2022","journal-title":"Pathogens"},{"issue":"8","key":"10.1016\/j.jiac.2025.102845_bib25","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.3201\/eid1608.100317","article-title":"Lethal necrotizing pneumonia caused by an ST398 Staphylococcus aureus strain","volume":"16","author":"Rasigade","year":"2010","journal-title":"Emerg Infect Dis"},{"issue":"1","key":"10.1016\/j.jiac.2025.102845_bib26","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3201\/eid2501.180684","article-title":"Severe disseminated infection with emerging lineage of methicillin-sensitive Staphylococcus aureus","volume":"25","author":"Jewell","year":"2019","journal-title":"Emerg Infect Dis"},{"issue":"9","key":"10.1016\/j.jiac.2025.102845_bib27","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.jiac.2022.05.011","article-title":"A fatal case of pneumonia and sepsis caused by sequence type 398 methicillin-susceptible Staphylococcus aureus carrying pantone-valentine leukocidin in China","volume":"28","author":"Zhang","year":"2022","journal-title":"J Infect Chemother"},{"issue":"2","key":"10.1016\/j.jiac.2025.102845_bib28","doi-asserted-by":"crossref","first-page":"232","DOI":"10.4103\/0255-0857.96706","article-title":"The first case of Staphylococcus aureus ST398 causing bacteremia in an immunocompromised patient in Greece","volume":"30","author":"Drougka","year":"2012","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.jiac.2025.102845_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2023.105408","article-title":"Comparative review of the nasal carriage and genetic characteristics of Staphylococcus aureus in healthy livestock: insight into zoonotic and anthroponotic clones","volume":"109","author":"Abdullahi","year":"2023","journal-title":"Infect Genet Evol"},{"issue":"2","key":"10.1016\/j.jiac.2025.102845_bib30","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3390\/antibiotics13020155","article-title":"Prevalence and genetic characterization of methicillin-resistant Staphylococcus aureus isolated from pigs in Japan","volume":"13","author":"Kawanishi","year":"2024","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.jiac.2025.102845_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jgar.2024.12.010","article-title":"Molecular characterization of methicillin-susceptible\/resistant Staphylococcus aureus from bloodstream infections in northern Japan: the dominance of CC1-MRSA-IV, the emergence of human-associated ST398 and livestock-associated CC20 and CC97 MSSA","volume":"41","author":"Aung","year":"2025","journal-title":"J Glob Antimicrob Resist"},{"issue":"11","key":"10.1016\/j.jiac.2025.102845_bib32","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.3390\/genes12111752","article-title":"The Staphylococcus aureus CC398 lineage: an evolution driven by the acquisition of prophages and other Mobile genetic elements","volume":"12","author":"Laumay","year":"2021","journal-title":"Genes"},{"issue":"5","key":"10.1016\/j.jiac.2025.102845_bib33","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1084\/jem.20031636","article-title":"Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent","volume":"199","author":"de Haas","year":"2004","journal-title":"J Exp Med"},{"issue":"11","key":"10.1016\/j.jiac.2025.102845_bib34","doi-asserted-by":"crossref","first-page":"6994","DOI":"10.4049\/jimmunol.172.11.6994","article-title":"Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor","volume":"172","author":"Postma","year":"2004","journal-title":"J Immunol"},{"issue":"11","key":"10.1016\/j.jiac.2025.102845_bib35","doi-asserted-by":"crossref","first-page":"8017","DOI":"10.4049\/jimmunol.177.11.8017","article-title":"A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1","volume":"177","author":"Prat","year":"2006","journal-title":"J Immunol"},{"issue":"10","key":"10.1016\/j.jiac.2025.102845_bib36","doi-asserted-by":"crossref","first-page":"6569","DOI":"10.4049\/jimmunol.0801523","article-title":"A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR","volume":"183","author":"Prat","year":"2009","journal-title":"J Immunol"},{"issue":"17","key":"10.1016\/j.jiac.2025.102845_bib37","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1038\/emboj.2012.212","article-title":"Staphylococcus aureus staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis","volume":"31","author":"Laarman","year":"2012","journal-title":"EMBO J"},{"issue":"9","key":"10.1016\/j.jiac.2025.102845_bib38","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1038\/ni1235","article-title":"Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases","volume":"6","author":"Rooijakkers","year":"2005","journal-title":"Nat Immunol"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25002429?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X25002429?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T10:03:41Z","timestamp":1764324221000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X25002429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":38,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1341321X25002429"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102845","relation":{},"ISSN":["1341-321X"],"issn-type":[{"type":"print","value":"1341-321X"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Whole-genome sequencing and in vitro characterization of a disseminated ST398 Staphylococcus aureus infection: A case report","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2025.102845","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102845"}}