{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T12:37:59Z","timestamp":1776775079521,"version":"3.51.2"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jiac.2026.102961","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T16:40:25Z","timestamp":1775666425000},"page":"102961","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhancing effects of Mycoplasma pneumoniae antigens on Th2-attracting chemokine responses by murine splenocytes"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5841-2625","authenticated-orcid":false,"given":"Satoshi","family":"Kurata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takako","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Yonezawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuhito","family":"Hojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Taguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jiac.2026.102961_bib1","first-page":"49","article-title":"Shared epitopes between Mycoplasma pneumoniae major adhesin protein P1 and a 140-kilodalton protein of Mycoplasma genitalium. Infect Immun","volume":"55","author":"Morrison-Plummer","year":"1987"},{"issue":"3693","key":"10.1016\/j.jiac.2026.102961_bib2","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1126\/science.150.3693.226","article-title":"Hemolysin of Mycoplasma pneumoniae: tentative identification as a peroxide","volume":"150","author":"Somerson","year":"1965","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.jiac.2026.102961_bib3","doi-asserted-by":"crossref","first-page":"2828","DOI":"10.1128\/IAI.73.5.2828-2834.2005","article-title":"Identification and characterization of human surfactant protein A binding protein of Mycoplasma pneumoniae","volume":"73","author":"Kannan","year":"2005","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.jiac.2026.102961_bib4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/oxfordjournals.aje.a121228","article-title":"Mycoplasma pneumoniae in the community","volume":"93","author":"Foy","year":"1971","journal-title":"Am J Epidemiol"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib5","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1093\/infdis\/127.4.388","article-title":"Mycoplasma pneumoniae infections in patients with immunodeficiency syndromes: report of four cases","volume":"127","author":"Foy","year":"1973","journal-title":"J Infect Dis"},{"issue":"6","key":"10.1016\/j.jiac.2026.102961_bib6","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s00415-004-0441-0","article-title":"Bilateral optic neuritis and Guillain-Barr\u00e9 syndrome following an acute Mycoplasma pneumoniae infection","volume":"251","author":"Ginestal","year":"2004","journal-title":"J Neurol"},{"issue":"6 Pt 1","key":"10.1016\/j.jiac.2026.102961_bib7","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0022-3476(87)80200-7","article-title":"Stevens-Johnson syndrome and Mycoplasma pneumoniae: evidence for cutaneous infection","volume":"111","author":"Stutman","year":"1987","journal-title":"J Pediatr"},{"issue":"11","key":"10.1016\/j.jiac.2026.102961_bib8","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1253\/jcj.42.1279","article-title":"A case of myocarditis caused by Mycoplasma pneumoniae","volume":"42","author":"Yamane","year":"1978","journal-title":"Jpn Circ J"},{"issue":"10","key":"10.1016\/j.jiac.2026.102961_bib9","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1136\/ard.51.10.1170","article-title":"Mycoplasmas and arthritis","volume":"51","author":"Hakkarainen","year":"1992","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib10","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1128\/CMR.17.4.697-728.2004","article-title":"Mycoplasma pneumoniae and its role as a human pathogen","volume":"17","author":"Waites","year":"2004","journal-title":"Clin Microbiol Rev"},{"issue":"3","key":"10.1016\/j.jiac.2026.102961_bib11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1542\/peds.55.3.327","article-title":"Respiratory infections due to Mycoplasma pneumoniae in infants and children","volume":"55","author":"Fernald","year":"1975","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib12","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1067\/mai.2001.113563","article-title":"A link between chronic asthma and chronic infection","volume":"107","author":"Martin","year":"2001","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.jiac.2026.102961_bib13","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1378\/chest.121.6.1782","article-title":"Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin","volume":"121","author":"Kraft","year":"2002","journal-title":"Chest"},{"issue":"Pt 6","key":"10.1016\/j.jiac.2026.102961_bib14","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1099\/jmm.0.007872-0","article-title":"Immunological analysis and pathological examination of gnotobiotic mice monoassociated with Mycoplasma pneumoniae","volume":"58","author":"Sekine","year":"2009","journal-title":"J Med Microbiol"},{"issue":"Pt 6","key":"10.1016\/j.jiac.2026.102961_bib15","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1099\/jmm.0.014191-0","article-title":"Antimicrobial and immunomodulatory effect of clarithromycin on macrolide-resistant Mycoplasma pneumoniae","volume":"59","author":"Kurata","year":"2010","journal-title":"J Med Microbiol"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib16","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1189\/jlb.0909639","article-title":"c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells","volume":"87","author":"Hiramatsu","year":"2010","journal-title":"J Leukoc Biol"},{"issue":"3","key":"10.1016\/j.jiac.2026.102961_bib17","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1574-695X.2008.00510.x","article-title":"Suppressive effects of Bifidobacterium longum on the production of Th2-attracting chemokines induced with T cell-antigen-presenting cell interactions","volume":"55","author":"Iwabuchi","year":"2009","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"1","key":"10.1016\/j.jiac.2026.102961_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001459","article-title":"Murine dendritic cells transcriptional modulation upon Paracoccidioides brasiliensis infection","volume":"6","author":"Tavares","year":"2012","journal-title":"PLoS Neglected Trop Dis"},{"issue":"7","key":"10.1016\/j.jiac.2026.102961_bib19","doi-asserted-by":"crossref","first-page":"4641","DOI":"10.4049\/jimmunol.175.7.4641","article-title":"A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6","volume":"175","author":"Shimizu","year":"2005","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.jiac.2026.102961_bib20","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1128\/IAI.00955-07","article-title":"Mycoplasma pneumoniae-Derived lipopeptides induce acute inflammatory responses in the lungs of mice","volume":"76","author":"Shimizu","year":"2008","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.jiac.2026.102961_bib21","doi-asserted-by":"crossref","first-page":"E39","DOI":"10.1542\/peds.107.3.e39","article-title":"Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production","volume":"107","author":"Koh","year":"2001","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.jiac.2026.102961_bib22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2174\/1568010023344661","article-title":"IL-4 and IL-13: their pathological roles in allergic diseases and their potential in developing new therapies","volume":"1","author":"Izuhara","year":"2002","journal-title":"Curr Drug Targets - Inflamm Allergy"},{"issue":"2","key":"10.1016\/j.jiac.2026.102961_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1006\/cyto.2000.0814","article-title":"Localization of human interleukin 13 receptor in non-haematopoietic cells","volume":"13","author":"Akaiwa","year":"2001","journal-title":"Cytokine"},{"issue":"6","key":"10.1016\/j.jiac.2026.102961_bib24","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1172\/JCI5909","article-title":"Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production","volume":"103","author":"Zhu","year":"1999","journal-title":"J Clin Investig"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/hmg\/9.4.549","article-title":"Genetic variants of IL-13 signalling and human asthma and atopy","volume":"9","author":"Heinzmann","year":"2000","journal-title":"Hum Mol Genet"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib26","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.4049\/jimmunol.165.4.2205","article-title":"Inducible expression of a Th2-type CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells","volume":"165","author":"Sekiya","year":"2000","journal-title":"J Immunol"},{"issue":"35","key":"10.1016\/j.jiac.2026.102961_bib27","doi-asserted-by":"crossref","first-page":"21514","DOI":"10.1074\/jbc.271.35.21514","article-title":"Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector","volume":"271","author":"Imai","year":"1996","journal-title":"J Biol Chem"},{"issue":"9","key":"10.1016\/j.jiac.2026.102961_bib28","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1084\/jem.185.9.1595","article-title":"Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells","volume":"185","author":"Godiska","year":"1997","journal-title":"J Exp Med"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib29","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1128\/iai.61.4.1352-1358.1993","article-title":"Toxicity of pneumolysin to pulmonary alveolar epithelial cells","volume":"61","author":"Rubins","year":"1993","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.jiac.2026.102961_bib30","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1128\/iai.60.5.1740-1746.1992","article-title":"Toxicity of pneumolysin to pulmonary endothelial cells in vitro","volume":"60","author":"Rubins","year":"1992","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.jiac.2026.102961_bib31","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/nrmicro1871","article-title":"The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease","volume":"6","author":"Kadioglu","year":"2008","journal-title":"Nat Rev Microbiol"},{"issue":"2","key":"10.1016\/j.jiac.2026.102961_bib32","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1128\/IAI.68.2.953-955.2000","article-title":"Capsular polysaccharide is a major complement resistance factor in lipopolysaccharide O side chain-deficient Klebsiella pneumoniae clinical isolates","volume":"68","author":"Alvarez","year":"2000","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.jiac.2026.102961_bib33","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1128\/IAI.70.5.2583-2590.2002","article-title":"Molecular analysis of the contribution of the capsular polysaccharide and the lipopolysaccharide O side chain to the virulence of Klebsiella pneumoniae in a murine model of pneumonia","volume":"70","author":"Cort\u00e9s","year":"2002","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.jiac.2026.102961_bib34","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1128\/IAI.05114-11","article-title":"Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2","volume":"79","author":"Bachman","year":"2011","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.jiac.2026.102961_bib35","first-page":"681","article-title":"Purification and characterization of Klebsiella pneumoniae cytotoxins","volume":"37","author":"Singh","year":"1999","journal-title":"Indian J Exp Biol"},{"issue":"2","key":"10.1016\/j.jiac.2026.102961_bib36","first-page":"135","article-title":"[Hydrolytic and haemolytic activity of Klebsiella pneumoniae and Klebsiella oxytoca]","volume":"58","author":"Sekowska","year":"2006","journal-title":"Med Dosw Mikrobiol"},{"key":"10.1016\/j.jiac.2026.102961_bib37","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/1471-2180-14-156","article-title":"Role of IL-17A and IL-10 in the antigen induced inflammation model by Mycoplasma pneumoniae","volume":"14","author":"Kurata","year":"2014","journal-title":"BMC Microbiol"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X26000590?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X26000590?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:41:47Z","timestamp":1776771707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X26000590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1341321X26000590"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2026.102961","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancing effects of Mycoplasma pneumoniae antigens on Th2-attracting chemokine responses by murine splenocytes","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2026.102961","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102961"}}