{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T11:54:59Z","timestamp":1781524499497,"version":"3.54.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jiac.2026.102996","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T16:16:15Z","timestamp":1778602575000},"page":"102996","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of the antimicrobial stewardship incentive program on antimicrobial supply instability: An interrupted time-series analysis using national drug supply data"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6693-3821","authenticated-orcid":false,"given":"Akira","family":"Kurishima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuji","family":"Koizumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiharu","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jiac.2026.102996_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2021-006961","article-title":"Shortage of essential antimicrobials: a major challenge to global health security","volume":"6","author":"Shafiq","year":"2021","journal-title":"BMJ Glob Health"},{"key":"10.1016\/j.jiac.2026.102996_bib2","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1093\/cid\/ciaa216","article-title":"Critical national shortage of cefazolin in Japan: management strategies","volume":"71","author":"Honda","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2026.102996_bib3","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/13696998.2022.2054202","article-title":"How China controls the Covid-19 epidemic through public health expenditure and policy?","volume":"25","author":"Jin","year":"2022","journal-title":"J Med Econ"},{"key":"10.1016\/j.jiac.2026.102996_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6658070","article-title":"COVID-19 vaccine, TRIPS, and global health diplomacy: india's role at the WTO platform","volume":"2021","author":"Chattu","year":"2021","journal-title":"BioMed Res Int"},{"key":"10.1016\/j.jiac.2026.102996_bib5","series-title":"Materials","article-title":"First meeting of the stakeholders\u2019 meeting on securing stable supply of pharmaceuticals","year":"2020"},{"key":"10.1016\/j.jiac.2026.102996_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1248\/yakushi.22-00185","article-title":"Shortages of prescription drugs due to compliance and quality issues in Japan","volume":"143","author":"Izutsu","year":"2023","journal-title":"Yakugaku Zasshi"},{"key":"10.1016\/j.jiac.2026.102996_bib7","first-page":"140","article-title":"Recent non-conformity with PMD act at pharmaceutical manufacturing sites and preventing measures for reoccurrence of such non-conformity","volume":"71","author":"Tobita","year":"2022","journal-title":"J Natl Inst Public Health"},{"key":"10.1016\/j.jiac.2026.102996_bib9","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.xphs.2023.03.006","article-title":"Generic drug shortage in Japan: GMP noncompliance and associated quality issues","volume":"112","author":"Izutsu","year":"2023","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.jiac.2026.102996_bib10","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S1473-3099(17)30325-0","article-title":"Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis","volume":"17","author":"Baur","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jiac.2026.102996_bib11","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1093\/cid\/ciw118","article-title":"Implementing an antibiotic stewardship program: guidelines by the infectious diseases society of America and the society for healthcare epidemiology of America","volume":"62","author":"Barlam","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jiac.2026.102996_bib12","doi-asserted-by":"crossref","first-page":"3384","DOI":"10.1093\/jac\/dkz321","article-title":"Adaptation of the WHO essential medicines list for national antibiotic stewardship policy in England: being AWaRe","volume":"74","author":"Budd","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jiac.2026.102996_bib13","article-title":"Antibiotic stewardship in primary care: evidence from pay-for-performance in France","author":"Chon\u00e9","year":"2025","journal-title":"Toulouse Sch Econ"},{"key":"10.1016\/j.jiac.2026.102996_bib14","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2025.55843","article-title":"National pilot program for antimicrobial stewardship in the Republic of Korea","volume":"9","author":"Lee","year":"2026","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jiac.2026.102996_bib15","unstructured":"Ministry of Health, Labour and Welfare (Japan). Overview of the 2024 revision of medical service fees:infection control measures in the post-COVID-19 era, https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/0000196352_00012.html, [accessed 1 February 2026]."},{"key":"10.1016\/j.jiac.2026.102996_bib16","unstructured":"The WHO. AWaRe (Access, watch, reserve) antibiotic book, https:\/\/www.who.int\/publications\/i\/item\/9789240062382, [accessed 1 February 2026]."},{"key":"10.1016\/j.jiac.2026.102996_bib18","unstructured":"Japan Pharmaceutical Manufacturers Association (JPMA). Revision of definitions related to the supply status of ethical drugs and the survey on pharmaceutical supply status conducted from April onwards Stability Assurance Committee. Report, https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/iryou\/kouhatu-iyaku\/04_00002.html, [accessed 1 February 2026]."},{"key":"10.1016\/j.jiac.2026.102996_bib21","series-title":"OECD health working papers no. 137","article-title":"Shortages of medicines in OECD countries","author":"Chapman","year":"2022"},{"key":"10.1016\/j.jiac.2026.102996_bib22","first-page":"180","article-title":"Medicines shortages: global approaches to addressing shortages of essential medicines","volume":"30","year":"2016","journal-title":"WHO Drug Inf"},{"key":"10.1016\/j.jiac.2026.102996_bib23","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1186\/s12913-022-08504-2","article-title":"Changes in on-time vaccination following the introduction of an electronic immunization registry, Tanzania 2016\u20132018: interrupted time-series analysis","volume":"22","author":"Dolan","year":"2022","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.jiac.2026.102996_bib24","series-title":"Nippon AMR one health report","year":"2025"},{"key":"10.1016\/j.jiac.2026.102996_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jiac.2024.08.023","article-title":"Chronic amoxicillin shortage led to alternative broad-spectrum antimicrobial use in pediatric clinics","volume":"31","author":"Otsubo","year":"2025","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.jiac.2026.102996_bib26","article-title":"Impact of antimicrobial resistance measures and the emergence of COVID-19 on antimicrobial use throughout the Japanese population: a retrospective cohort study using a national claims database","volume":"67","author":"Koizumi","year":"2026","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jiac.2026.102996_bib27","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.cmi.2024.12.005","article-title":"Trends in antimicrobial consumption: Long-term impact of the COVID-19 pandemic","volume":"31","author":"Tsuzuki","year":"2025","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jiac.2026.102996_bib28","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1186\/s12913-021-07139-z","article-title":"Effects of the cefazolin shortage on the sales, cost, and appropriate use of other antimicrobials","volume":"21","author":"Koizumi","year":"2021","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.jiac.2026.102996_bib29","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jiph.2023.01.021","article-title":"Impact of the cefazolin shortage on the selection and cost of parenteral antibiotics during the supply disruption period in Japan: a controlled interrupted time series analysis","volume":"16","author":"Nagano","year":"2023","journal-title":"J Infect Public Health"},{"key":"10.1016\/j.jiac.2026.102996_bib30","series-title":"Sales 2013\u20132024 report","year":"2024"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X26000942?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X26000942?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T11:26:35Z","timestamp":1781522795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X26000942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S1341321X26000942"],"URL":"https:\/\/doi.org\/10.1016\/j.jiac.2026.102996","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of the antimicrobial stewardship incentive program on antimicrobial supply instability: An interrupted time-series analysis using national drug supply data","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jiac.2026.102996","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102996"}}