{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:26:48Z","timestamp":1788830808099,"version":"build-2803163510"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.jid.2015.12.003","type":"journal-article","created":{"date-parts":[[2015,12,15]],"date-time":"2015-12-15T11:56:12Z","timestamp":1450180572000},"page":"715-718","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair\u00a0Loss"],"prefix":"10.1016","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7150-4052","authenticated-orcid":false,"given":"Jane","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"van Vliet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas W.","family":"Rufaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie\u00a0N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney\u00a0D.","family":"Sinclair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis\u00a0R.","family":"Carbone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2015.12.003_bib1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.it.2012.08.008","article-title":"Peripheral tissue surveillance and residency by memory T cells","volume":"34","author":"Gebhardt","year":"2013","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jid.2015.12.003_bib2","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1056\/NEJMra1103442","article-title":"Alopecia areata","volume":"366","author":"Gilhar","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2015.12.003_bib3","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1038\/sj.jid.5700328","article-title":"A\u00a0chronic contact eczema impedes migration of antigen-presenting cells in alopecia areata","volume":"126","author":"Gupta","year":"2006","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2015.12.003_bib4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jdermsci.2012.12.003","article-title":"CXCL10 produced from hair follicles induces Th1 and Tc1 cell infiltration in the acute phase of alopecia areata followed by sustained Tc1 accumulation in the chronic phase","volume":"69","author":"Ito","year":"2013","journal-title":"J\u00a0Dermatol Sci"},{"key":"10.1016\/j.jid.2015.12.003_bib5","article-title":"Clinical observations in alopecia areata: implications and hypotheses","author":"Li","year":"2014","journal-title":"Australas J\u00a0Dermatol"},{"key":"10.1016\/j.jid.2015.12.003_bib6","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1038\/jid.2012.17","article-title":"Increased expression of Cxcr3 and its ligands, Cxcl9 and Cxcl10, during the development of alopecia areata in the mouse","volume":"132","author":"McPhee","year":"2012","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2015.12.003_bib7","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/ni.2353","article-title":"Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin","volume":"13","author":"Nagao","year":"2012","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2015.12.003_bib8","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1038\/jidsymp.2013.7","article-title":"The role of hair follicle immune privilege collapse in alopecia areata: status and perspectives","volume":"16","author":"Paus","year":"2013","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2015.12.003_bib9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature09114","article-title":"Genome-wide association study in alopecia areata implicates both innate and adaptive immunity","volume":"466","author":"Petukhova","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.jid.2015.12.003_bib10","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ygeno.2010.05.002","article-title":"Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures","volume":"96","author":"Subramanya","year":"2010","journal-title":"Genomics"},{"key":"10.1016\/j.jid.2015.12.003_bib11","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/nm.3645","article-title":"Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition","volume":"20","author":"Xing","year":"2014","journal-title":"Nat Med"},{"key":"10.1016\/j.jid.2015.12.003_bib12","doi-asserted-by":"crossref","first-page":"3744","DOI":"10.1096\/fj.10-155879","article-title":"The cystatin M\/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea","volume":"24","author":"Zeeuwen","year":"2010","journal-title":"FASEB J"},{"key":"10.1016\/j.jid.2015.12.003_bib13","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.immuni.2012.05.008","article-title":"The chemokine superfamily revisited","volume":"36","author":"Zlotnik","year":"2012","journal-title":"Immunity"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15000949?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15000949?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T20:41:08Z","timestamp":1542919268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15000949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S0022202X15000949"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2015.12.003","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair\u00a0Loss","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2015.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Authors. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}