{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T17:47:07Z","timestamp":1779904027477,"version":"3.53.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.jid.2016.04.035","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T00:30:18Z","timestamp":1463531418000},"page":"1820-1830","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature"],"prefix":"10.1016","volume":"136","author":[{"given":"William R.","family":"Swindell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal K.","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianying","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann E.","family":"Gudjonsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2016.04.035_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-0960.2004.00025.x","article-title":"Squamous cell carcinoma in situ of the skin: history, presentation, biology and treatment","volume":"45","author":"Arlette","year":"2004","journal-title":"Australas J Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib2","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1046\/j.1365-2133.2003.05319.x","article-title":"Circulating natural killer cells in psoriasis","volume":"149","author":"Cameron","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib3","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.jaci.2012.06.044","article-title":"Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation","volume":"130","author":"Choy","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2016.04.035_bib4","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1038\/jid.2014.532","article-title":"IL-36gamma (IL-1F9) is a biomarker for psoriasis skin lesions","volume":"135","author":"D'Erme","year":"2015","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib5","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jaci.2013.04.043","article-title":"Attenuated neutrophil axis in atopic dermatitis compared to psoriasis reflects TH17 pathway differences between these diseases","volume":"132","author":"Dhingra","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2016.04.035_bib6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0140-6736(15)60125-8","article-title":"Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials","volume":"386","author":"Griffiths","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.jid.2016.04.035_bib7","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/sj.jid.5700157","article-title":"Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia","volume":"126","author":"Haider","year":"2006","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib8","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/jid.2014.352","article-title":"Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis","volume":"135","author":"Inkeles","year":"2015","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib9","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/jid.2011.267","article-title":"Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes","volume":"132","author":"Jabbari","year":"2012","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib10","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1186\/s12864-015-1508-2","article-title":"Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN","volume":"16","author":"Keermann","year":"2015","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jid.2016.04.035_bib11","doi-asserted-by":"crossref","first-page":"R36","DOI":"10.1186\/gb-2013-14-4-r36","article-title":"TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions","volume":"14","author":"Kim","year":"2013","journal-title":"Genome Biol"},{"key":"10.1016\/j.jid.2016.04.035_bib12","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1056\/NEJMoa1314258","article-title":"Secukinumab in plaque psoriasis\u2014results of two phase 3 trials","volume":"371","author":"Langley","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2016.04.035_bib13","doi-asserted-by":"crossref","first-page":"R29","DOI":"10.1186\/gb-2014-15-2-r29","article-title":"voom: precision weights unlock linear model analysis tools for RNA-seq read counts","volume":"15","author":"Law","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jid.2016.04.035_bib14","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1056\/NEJMoa1503824","article-title":"Phase 3 studies comparing brodalumab with ustekinumab in psoriasis","volume":"373","author":"Lebwohl","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2016.04.035_bib15","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1038\/jid.2014.28","article-title":"Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms","volume":"134","author":"Li","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2016.04.035_bib16","doi-asserted-by":"crossref","first-page":"5247","DOI":"10.4049\/jimmunol.176.9.5247","article-title":"Autoreactive T cells mediate NK cell degeneration in autoimmune disease","volume":"176","author":"Liu","year":"2006","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2016.04.035_bib17","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.jaci.2003.08.049","article-title":"Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis","volume":"112","author":"Nomura","year":"2003","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2016.04.035_bib18","doi-asserted-by":"crossref","first-page":"223ra222","DOI":"10.1126\/scitranslmed.3007217","article-title":"Integrative biology approach identifies cytokine targeting strategies for psoriasis","volume":"6","author":"Perera","year":"2014","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jid.2016.04.035_bib19","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrg3394","article-title":"Reuse of public genome-wide gene expression data","volume":"14","author":"Rung","year":"2013","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.jid.2016.04.035_bib20","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/nri1935","article-title":"Reciprocal regulation between natural killer cells and autoreactive T cells","volume":"6","author":"Shi","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jid.2016.04.035_bib21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3109\/08916931003782122","article-title":"Natural killer cells as indispensable players and therapeutic targets in autoimmunity","volume":"44","author":"Shi","year":"2011","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jid.2016.04.035_bib22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2202\/1544-6115.1027","article-title":"Linear models and empirical Bayes methods for assessing differential expression in microarray experiments","volume":"3","author":"Smyth","year":"2004","journal-title":"Stat Appl Genet Mol Biol"},{"key":"10.1016\/j.jid.2016.04.035_bib23","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1186\/1471-2164-14-527","article-title":"Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients","volume":"14","author":"Swindell","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jid.2016.04.035_bib24","doi-asserted-by":"crossref","first-page":"e79253","DOI":"10.1371\/journal.pone.0079253","article-title":"Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation","volume":"8","author":"Swindell","year":"2013","journal-title":"PloS ONE"},{"key":"10.1016\/j.jid.2016.04.035_bib25","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s13073-015-0208-5","article-title":"Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance","volume":"7","author":"Swindell","year":"2015","journal-title":"Genome Med"},{"key":"10.1016\/j.jid.2016.04.035_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s40169-015-0054-5","article-title":"Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites","volume":"4","author":"Swindell","year":"2015","journal-title":"Clin Transl Med"},{"key":"10.1016\/j.jid.2016.04.035_bib27","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1755-8794-7-27","article-title":"Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era","volume":"7","author":"Swindell","year":"2014","journal-title":"BMC Med Genomics"},{"key":"10.1016\/j.jid.2016.04.035_bib28","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1152\/physiolgenomics.00022.2014","article-title":"Integrative RNA-seq and microarray data analysis reveals GC content and gene length biases in the psoriasis transcriptome","volume":"46","author":"Swindell","year":"2014","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.jid.2016.04.035_bib29","doi-asserted-by":"crossref","first-page":"e44274","DOI":"10.1371\/journal.pone.0044274","article-title":"Meta-analysis derived (MAD) transcriptome of psoriasis defines the \u201ccore\u201d pathogenesis of disease","volume":"7","author":"Tian","year":"2012","journal-title":"PloS ONE"},{"key":"10.1016\/j.jid.2016.04.035_bib30","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s13059-014-0570-4","article-title":"Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin","volume":"16","author":"Tsoi","year":"2015","journal-title":"Genome Biol"},{"key":"10.1016\/j.jid.2016.04.035_bib31","doi-asserted-by":"crossref","first-page":"e29161","DOI":"10.1371\/journal.pone.0029161","article-title":"Interferon and biologic signatures in dermatomyositis skin: specificity and heterogeneity across diseases","volume":"7","author":"Wong","year":"2012","journal-title":"PloS ONE"},{"key":"10.1016\/j.jid.2016.04.035_bib32","doi-asserted-by":"crossref","first-page":"e2737","DOI":"10.1371\/journal.pone.0002737","article-title":"Type I interferon: potential therapeutic target for psoriasis?","volume":"3","author":"Yao","year":"2008","journal-title":"PloS ONE"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X16312465?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X16312465?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T12:19:58Z","timestamp":1543321198000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X16312465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":32,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0022202X16312465"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2016.04.035","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2016.04.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}