{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T13:49:34Z","timestamp":1781272174749,"version":"3.54.1"},"reference-count":63,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jid.2017.09.024","type":"journal-article","created":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T16:33:30Z","timestamp":1506616410000},"page":"500-510","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion"],"prefix":"10.1016","volume":"138","author":[{"given":"Chiara","family":"Sardella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Winkler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Quignodon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Hardman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Toffoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta Maria Paola","family":"Giordano Attianese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer E.","family":"Hundt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliane","family":"Michalik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles R.","family":"Vinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Paus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Desvergne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Gilardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2017.09.024_bib1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/exd.12208","volume":"22","author":"Adachi","year":"2013","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib2","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nm.3159","article-title":"PPARgamma signaling and metabolism: the good, the bad and the future","volume":"19","author":"Ahmadian","year":"2013","journal-title":"Nat Med"},{"key":"10.1016\/j.jid.2017.09.024_bib3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S1097-2765(00)80209-9","article-title":"PPAR gamma is required for placental, cardiac, and adipose tissue development","volume":"4","author":"Barak","year":"1999","journal-title":"Mol Cell"},{"issue":"2","key":"10.1016\/j.jid.2017.09.024_bib4","doi-asserted-by":"crossref","first-page":"C335","DOI":"10.1152\/ajpcell.2000.279.2.C335","article-title":"Functional TSH receptor in human abdominal preadipocytes and orbital fibroblasts","volume":"279","author":"Bell","year":"2000","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.jid.2017.09.024_bib5","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1080\/000155500459240","article-title":"Expression of peroxisome proliferator activated receptors (PPARs) in human hair follicles and PPAR alpha involvement in hair growth","volume":"80","author":"Billoni","year":"2000","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jid.2017.09.024_bib6","doi-asserted-by":"crossref","first-page":"4709","DOI":"10.1242\/dev.067710","article-title":"Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis","volume":"138","author":"Birsoy","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.jid.2017.09.024_bib7","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1038\/jid.2008.361","article-title":"Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormone","volume":"129","author":"Bodo","year":"2008","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib8","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1172\/JCI0213880","article-title":"Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands","volume":"109","author":"Chen","year":"2002","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jid.2017.09.024_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4161\/21623945.2014.955402","article-title":"Differentiation and characterization of human facial subcutaneous adipocytes","volume":"4","author":"Chon","year":"2015","journal-title":"Adipocyte"},{"key":"10.1016\/j.jid.2017.09.024_bib10","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1210\/me.2004-0088","article-title":"Be fit or be sick: peroxisome proliferator-activated receptors are down the road","volume":"18","author":"Desvergne","year":"2004","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.jid.2017.09.024_bib11","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1152\/physrev.00025.2005","article-title":"Transcriptional regulation of metabolism","volume":"86","author":"Desvergne","year":"2006","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jid.2017.09.024_bib12","doi-asserted-by":"crossref","first-page":"E1501","DOI":"10.1073\/pnas.1312880111","article-title":"Epidermal Wnt\/beta-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors","volume":"111","author":"Donati","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2017.09.024_bib13","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1038\/jid.2013.413","article-title":"PPARgamma-mediated and arachidonic acid-dependent signaling is involved in differentiation and lipid production of human sebocytes","volume":"134","author":"Dozsa","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/exd.12450","article-title":"Defining dermal adipose tissue","volume":"23","author":"Driskell","year":"2014","journal-title":"Exp Dermatol"},{"issue":"7479","key":"10.1016\/j.jid.2017.09.024_bib15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/nature12783","article-title":"Distinct fibroblast lineages determine dermal architecture in skin development and repair","volume":"504","author":"Driskell","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.jid.2017.09.024_bib16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.cell.2011.07.019","article-title":"Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling","volume":"146","author":"Festa","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.jid.2017.09.024_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1365-4632.2009.04144.x","article-title":"Committed differentiation of hair follicle bulge cells into sebocytes: an in\u00a0vitro study","volume":"49","author":"Fu","year":"2010","journal-title":"Int J Dermatol"},{"issue":"7130","key":"10.1016\/j.jid.2017.09.024_bib18","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature05659","article-title":"Scratching the surface of skin development","volume":"445","author":"Fuchs","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jid.2017.09.024_bib19","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1101\/gad.1645908","article-title":"More than one way to skin","volume":"22","author":"Fuchs","year":"2008","journal-title":"Genes Dev"},{"key":"10.1016\/j.jid.2017.09.024_bib20","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/brv.12151","article-title":"Resting no more: re-defining telogen, the maintenance stage of the hair growth cycle","volume":"90","author":"Geyfman","year":"2015","journal-title":"Biol Rev Camb Philos Soc"},{"key":"10.1016\/j.jid.2017.09.024_bib21","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/path.4233","article-title":"Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche","volume":"231","author":"Harries","year":"2013","journal-title":"J\u00a0Pathol"},{"key":"10.1016\/j.jid.2017.09.024_bib22","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.2353\/ajpath.2010.100454","article-title":"The pathogenesis of primary cicatricial alopecias","volume":"177","author":"Harries","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jid.2017.09.024_bib23","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1242\/jcs.122333","article-title":"Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation","volume":"126","author":"Heinke","year":"2013","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jid.2017.09.024_bib24","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.0022-202X.2005.23787.x","article-title":"A\u00a0guide to assessing damage response pathways of the hair follicle: lessons from cyclophosphamide-induced alopecia in mice","volume":"125","author":"Hendrix","year":"2005","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib25","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1083\/jcb.200207080","article-title":"Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy","volume":"161","author":"Herrmann","year":"2003","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jid.2017.09.024_bib26","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/sj.jidsymp.5650007","article-title":"Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis","volume":"11","author":"Icre","year":"2006","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2017.09.024_bib27","doi-asserted-by":"crossref","first-page":"4543","DOI":"10.1073\/pnas.0400356101","article-title":"Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse","volume":"101","author":"Imai","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2017.09.024_bib28","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1038\/jid.2008.369","article-title":"Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia","volume":"129","author":"Karnik","year":"2009","journal-title":"J\u00a0Invest Dermatol"},{"issue":"8","key":"10.1016\/j.jid.2017.09.024_bib29","doi-asserted-by":"crossref","first-page":"e1004514","DOI":"10.1371\/journal.pgen.1004514","article-title":"Syndecan-1 is required to maintain intradermal fat and prevent cold stress","volume":"10","author":"Kasza","year":"2014","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jid.2017.09.024_bib30","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/exd.12941","article-title":"Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot?","volume":"25","author":"Kruglikov","year":"2016","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib31","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1046\/j.0022-202x.2001.01368.x","article-title":"Patterns of proliferation and apoptosis during murine hair follicle morphogenesis","volume":"116","author":"Magerl","year":"2001","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib32","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1002\/art.38990","article-title":"Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors","volume":"67","author":"Marangoni","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.jid.2017.09.024_bib33","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.jid.2016.01.036","article-title":"\u03b2-catenin stabilization in skin fibroblasts causes fibrotic lesions by reventing adipocyte differentiation of the reticular dermis","volume":"136","author":"Mastrogiannaki","year":"2016","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib34","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.jaad.2014.10.036","article-title":"The use of oral pioglitazone in the treatment of lichen planopilaris","volume":"72","author":"Mesinkovska","year":"2015","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib35","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/archdermatol.2009.283","article-title":"Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist","volume":"145","author":"Mirmirani","year":"2009","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib36","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1101\/gad.12.20.3168","article-title":"Life without white fat: a transgenic mouse","volume":"12","author":"Moitra","year":"1998","journal-title":"Genes Dev"},{"key":"10.1016\/j.jid.2017.09.024_bib37","doi-asserted-by":"crossref","first-page":"5664","DOI":"10.1128\/MCB.23.16.5664-5679.2003","article-title":"BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation","volume":"23","author":"Moser","year":"2003","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jid.2017.09.024_bib38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.0022-202x.2001.01377.x","article-title":"A\u00a0comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages","volume":"117","author":"Muller-Rover","year":"2001","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib39","doi-asserted-by":"crossref","first-page":"4969","DOI":"10.1210\/en.2010-0131","article-title":"PPARgamma in placental angiogenesis","volume":"151","author":"Nadra","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.jid.2017.09.024_bib40","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jaci.2011.11.034","article-title":"PGD2 induces eotaxin-3 via PPARgamma from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis","volume":"129","author":"Nakahigashi","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2017.09.024_bib41","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1046\/j.1523-1747.1999.00740.x","article-title":"A\u00a0comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis","volume":"113","author":"Paus","year":"1999","journal-title":"J\u00a0Invest Dermatol"},{"issue":"1","key":"10.1016\/j.jid.2017.09.024_bib42","doi-asserted-by":"crossref","first-page":"a015198","DOI":"10.1101\/cshperspect.a015198","article-title":"Macroenvironmental regulation of hair cycling and collective regenerative behavior","volume":"4","author":"Plikus","year":"2014","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"6326","key":"10.1016\/j.jid.2017.09.024_bib43","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1126\/science.aai8792","article-title":"Regeneration of fat cells from myofibroblasts during wound healing","volume":"355","author":"Plikus","year":"2017","journal-title":"Science"},{"issue":"7176","key":"10.1016\/j.jid.2017.09.024_bib44","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/nature06457","article-title":"Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration","volume":"451","author":"Plikus","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jid.2017.09.024_bib45","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/exd.12647","article-title":"The role of PPARgamma-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology","volume":"24","author":"Ramot","year":"2015","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib46","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1038\/jid.2013.473","article-title":"Advanced inhibition of undesired human hair growth by PPARgamma modulation?","volume":"134","author":"Ramot","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib47","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S1097-2765(00)80211-7","article-title":"PPAR gamma is required for the differentiation of adipose tissue in\u00a0vivo and in\u00a0vitro","volume":"4","author":"Rosen","year":"1999","journal-title":"Mol Cell"},{"key":"10.1016\/j.jid.2017.09.024_bib48","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1242\/dev.087593","article-title":"Intradermal adipocytes mediate fibroblast recruitment during skin wound healing","volume":"140","author":"Schmidt","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.jid.2017.09.024_bib49","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/bies.20184","article-title":"Molecular principles of hair follicle induction and morphogenesis","volume":"27","author":"Schmidt-Ullrich","year":"2005","journal-title":"Bioessays"},{"key":"10.1016\/j.jid.2017.09.024_bib50","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.semcdb.2012.08.011","article-title":"Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling","volume":"23","author":"Sennett","year":"2012","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.jid.2017.09.024_bib51","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.devcel.2015.06.023","article-title":"An integrated transcriptome atlas of embryonic hair follicle progenitors, their niche, and the developing skin","volume":"34","author":"Sennett","year":"2015","journal-title":"Dev Cell"},{"key":"10.1016\/j.jid.2017.09.024_bib52","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1152\/physrev.2001.81.1.449","article-title":"Controls of hair follicle cycling","volume":"81","author":"Stenn","year":"2001","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jid.2017.09.024_bib53","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1038\/sj.jid.5701200","article-title":"Phylogeny of the hair follicle: the sebogenic hypothesis","volume":"128","author":"Stenn","year":"2008","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.024_bib54","doi-asserted-by":"crossref","first-page":"11767","DOI":"10.1074\/jbc.M311000200","article-title":"Lipopenia and skin barrier abnormalities in DGAT2-deficient mice","volume":"279","author":"Stone","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jid.2017.09.024_bib55","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.it.2007.09.003","article-title":"Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms","volume":"28","author":"Straus","year":"2007","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jid.2017.09.024_bib56","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/S0002-9440(10)65078-X","article-title":"Asebia-2J (Scd1(ab2J)): a new allele and a model for scarring alopecia","volume":"156","author":"Sundberg","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jid.2017.09.024_bib57","first-page":"416","article-title":"Epicardial adipose tissue: far more than a fat depot","volume":"4","author":"Talman","year":"2014","journal-title":"Cardiovasc Diagn Ther"},{"key":"10.1016\/j.jid.2017.09.024_bib58","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.bbadis.2011.02.014","article-title":"PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation","volume":"1812","author":"Varga","year":"2011","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jid.2017.09.024_bib59","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1101\/gad.1567207","article-title":"Maternal PPAR\u03b3 protects nursing neonates by suppressing the production of inflammatory milk","volume":"21","author":"Wan","year":"2007","journal-title":"Genes Dev"},{"issue":"46","key":"10.1016\/j.jid.2017.09.024_bib60","doi-asserted-by":"crossref","first-page":"18656","DOI":"10.1073\/pnas.1314863110","article-title":"Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARgamma","volume":"110","author":"Wang","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2017.09.024_bib61","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1101\/gad.285429.116","article-title":"Hair follicles' transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog","volume":"30","author":"Zhang","year":"2016","journal-title":"Genes Dev"},{"key":"10.1016\/j.jid.2017.09.024_bib62","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1634\/stemcells.2005-0544","article-title":"Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem\/progenitor cell activation and expansion","volume":"24","author":"Zhang","year":"2006","journal-title":"Stem Cells"},{"issue":"6217","key":"10.1016\/j.jid.2017.09.024_bib63","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1126\/science.1260972","article-title":"Innate immunity. Dermal adipocytes protect against invasive Staphylococcus aureus skin infection","volume":"347","author":"Zhang","year":"2015","journal-title":"Science"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X17329846?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X17329846?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,2]],"date-time":"2019-03-02T07:52:47Z","timestamp":1551513167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X17329846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":63,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0022202X17329846"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2017.09.024","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2017.09.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}