{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T15:57:46Z","timestamp":1782748666748,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jid.2017.09.046","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T06:38:38Z","timestamp":1512542318000},"page":"549-556","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Genome-Wide MicroRNA Analysis Implicates miR-30b\/d in the Etiology of\u00a0Alopecia Areata"],"prefix":"10.1016","volume":"138","author":[{"given":"Aylar","family":"Tafazzoli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas J.","family":"Forstner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Broadley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Redler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Petukhova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin A.","family":"Giehl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Kruse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Blaumeiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"B\u00f6hm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Bertolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Garcia Bartels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Lutz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Blume-Peytavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermona","family":"Soreq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Christiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia V.","family":"Botchkareva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus M.","family":"N\u00f6then","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina C.","family":"Betz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2017.09.046_bib1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1083\/jcb.201404001","article-title":"MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway","volume":"207","author":"Ahmed","year":"2014","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.jid.2017.09.046_bib2","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1517\/14712598.7.9.1387","article-title":"The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression","volume":"7","author":"Barnes","year":"2007","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.jid.2017.09.046_bib3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.jid.2017.09.046_bib5","doi-asserted-by":"crossref","first-page":"5966","DOI":"10.1038\/ncomms6966","volume":"6","author":"Betz","year":"2015","journal-title":"Nat Commun"},{"key":"10.1016\/j.jid.2017.09.046_bib6","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1101\/gr.109371.110","article-title":"Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts","volume":"21","author":"Borel","year":"2011","journal-title":"Genome Res"},{"key":"10.1016\/j.jid.2017.09.046_bib8","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.coi.2012.07.011","article-title":"MicroRNAs and autoimmunity","volume":"24","author":"Ceribelli","year":"2012","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.jid.2017.09.046_bib9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/sji.12261","article-title":"The role of microRNAs in autoimmune diseases with skin involvement","volume":"81","author":"Deng","year":"2015","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.jid.2017.09.046_bib10","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ajhg.2016.03.027","article-title":"Mechanisms and disease associations of haplotype-dependent allele-specific DNA methylation","volume":"98","author":"Do","year":"2016","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jid.2017.09.046_bib11","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nrg2809","article-title":"Missing heritability and strategies for finding the underlying causes of complex disease","volume":"11","author":"Eichler","year":"2010","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.jid.2017.09.046_bib13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3389\/fnmol.2013.00047","article-title":"MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review","volume":"6","author":"Forstner","year":"2013","journal-title":"Front Mol Neurosci"},{"key":"10.1016\/j.jid.2017.09.046_bib14","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/tp.2015.159","article-title":"Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder","volume":"5","author":"Forstner","year":"2015","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.jid.2017.09.046_bib16","doi-asserted-by":"crossref","first-page":"65165","DOI":"10.1371\/journal.pone.0065165","article-title":"Genome-wide and species-wide in silico screening for intragenic microRNAs in human, mouse and chicken","volume":"8","author":"Godnic","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jid.2017.09.046_bib18","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/JID.2015.409","article-title":"microRNAs in psoriasis","volume":"136","author":"Hawkes","year":"2016","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.046_bib20","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ebiom.2016.03.036","article-title":"Molecular signatures define alopecia areata subtypes and transcriptional biomarkers","volume":"7","author":"Jabbari","year":"2016","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jid.2017.09.046_bib21","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.1038\/jid.2012.129","article-title":"Follow-Up Study of the First Genome-Wide Association Scan in Alopecia Areata: IL13 and KIAA0350 as Susceptibility Loci Supported with Genome-Wide Significance","volume":"132","author":"Jagielska","year":"2012","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2017.09.046_bib22","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1093\/hmg\/ddr331","article-title":"Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome","volume":"20","author":"Joyce","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jid.2017.09.046_bib23","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/nar\/gkt1181","article-title":"MiRBase: Annotating high confidence microRNAs using deep sequencing data","volume":"42","author":"Kozomara","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2017.09.046_bib25","doi-asserted-by":"crossref","first-page":"10627","DOI":"10.1007\/s11033-012-1952-x","article-title":"Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis","volume":"39","author":"Lee","year":"2012","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.jid.2017.09.046_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cell.2004.12.035","article-title":"Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets","volume":"120","author":"Lewis","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.jid.2017.09.046_bib27","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ajhg.2010.06.009","article-title":"A\u00a0versatile gene-based test for genome-wide association studies","volume":"87","author":"Liu","year":"2010","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jid.2017.09.046_bib30","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/cei.12624","article-title":"MicroRNA-155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th17) cells","volume":"181","author":"Ma","year":"2015","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jid.2017.09.046_bib32","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1096\/fj.10-160663","article-title":"Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle","volume":"24","author":"Mardaryev","year":"2010","journal-title":"FASEB J"},{"key":"10.1016\/j.jid.2017.09.046_bib33","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.4049\/jimmunol.1401893","article-title":"miR-24, miR-30b, and miR-142-3p regulate phagocytosis in myeloid inflammatory cells","volume":"194","author":"Naqvi","year":"2015","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2017.09.046_bib34","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1007\/s00018-012-1117-z","article-title":"Control by a hair\u2019s breadth: The role of microRNAs in the skin","volume":"70","author":"Ning","year":"2013","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jid.2017.09.046_bib36","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/ng.1017","article-title":"Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis","volume":"44","author":"Paternoster","year":"2012","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2017.09.046_bib38","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature09114","article-title":"Genome-wide association study in alopecia areata implicates both innate and adaptive immunity","volume":"466","author":"Petukhova","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.jid.2017.09.046_bib40","first-page":"2336","article-title":"LocusZoom: regional visualization of genome-wide association scan results","volume":"27","author":"Pruim","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2017.09.046_bib41","first-page":"8","article-title":"MicroRNAs in autoimmune diseases","volume":"527895","author":"Qu","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jid.2017.09.046_bib45","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4065\/70.7.628","article-title":"Incidence of alopecia areata in Olmsted County, Minnesota, 1975 through 1989","volume":"70","author":"Safavi","year":"1995","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jid.2017.09.046_bib46","first-page":"9392132","article-title":"Emerging role and therapeutic implication of Wnt signaling pathways in autoimmune diseases","volume":"2016","author":"Shi","year":"2016","journal-title":"J\u00a0Immunol Res"},{"key":"10.1016\/j.jid.2017.09.046_bib48","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1093\/rheumatology\/ket254","article-title":"Alteration of circulating miRNAs in SSc: MiR-30b regulates the expression of PDGF receptor \u03b2","volume":"52","author":"Tanaka","year":"2013","journal-title":"Rheumatol"},{"key":"10.1016\/j.jid.2017.09.046_bib49","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.4161\/auto.20159","article-title":"Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori","volume":"8","author":"Tang","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.jid.2017.09.046_bib50","doi-asserted-by":"crossref","first-page":"1260419","DOI":"10.1126\/science.1260419","article-title":"Tissue-based map of the human proteome","volume":"347","author":"Uhl\u00e9n","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.jid.2017.09.046_bib56","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/gene.2017.4","article-title":"Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways","volume":"18","author":"Wang","year":"2017","journal-title":"Genes Immun"},{"key":"10.1016\/j.jid.2017.09.046_bib51","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/nar\/gkt439","article-title":"WEB-based GEne SeT AnaLysis Toolkit (WebGestalt)","volume":"41","author":"Wang","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2017.09.046_bib55","doi-asserted-by":"crossref","first-page":"e13798","DOI":"10.1371\/journal.pone.0013798","article-title":"RNA polymerase II binding patterns reveal genomic regions Involved in microRNA gene regulation","volume":"5","author":"Wang","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jid.2017.09.046_bib52","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/nar\/gkv1104","article-title":"BioGPS: building your own mash-up of gene annotations and expression profiles","volume":"44","author":"Wu","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2017.09.046_bib53","doi-asserted-by":"crossref","first-page":"4578230","DOI":"10.1155\/2016\/4578230","article-title":"MiRNAs participate in MS pathological processes and its therapeutic response","volume":"2016","author":"Wu","year":"2016","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.jid.2017.09.046_bib54","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/nm.3645","article-title":"Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition","volume":"20","author":"Xing","year":"2015","journal-title":"Nat Med"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X17330725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X17330725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,2]],"date-time":"2019-03-02T12:53:14Z","timestamp":1551531194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X17330725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0022202X17330725"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2017.09.046","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genome-Wide MicroRNA Analysis Implicates miR-30b\/d in the Etiology of\u00a0Alopecia Areata","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2017.09.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}