{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:26:17Z","timestamp":1768004777798,"version":"3.49.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King&apos;s College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009360","name":"King\u2019s College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009360","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000276","name":"Department of Health and Social Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.jid.2019.03.1130","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T12:03:53Z","timestamp":1553256233000},"page":"1975-1984.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Contribution of STAT3 and RAD23B in Primary S\u00e9zary Cells to Histone Deacetylase Inhibitor FK228 Resistance"],"prefix":"10.1016","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1063-9097","authenticated-orcid":false,"given":"Rosie M.","family":"Butler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8885-733X","authenticated-orcid":false,"given":"Robert C.","family":"McKenzie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9539-7458","authenticated-orcid":false,"given":"Christine L.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5913-9192","authenticated-orcid":false,"given":"Charlotte E.","family":"Flanagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5567-8765","authenticated-orcid":false,"given":"Wesley J.","family":"Woollard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1927-4987","authenticated-orcid":false,"given":"Maria","family":"Demontis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6865-5607","authenticated-orcid":false,"given":"Silvia","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2638-8539","authenticated-orcid":false,"given":"Isabella","family":"Tosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5620-1982","authenticated-orcid":false,"given":"Susan","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0972-2600","authenticated-orcid":false,"given":"Sean J.","family":"Whittaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8892-0642","authenticated-orcid":false,"given":"Tracey J.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2019.03.1130_bib1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0092-8674(00)81959-5","article-title":"Stat3 as an Oncogene","volume":"98","author":"Bromberg","year":"1999","journal-title":"Cell"},{"issue":"Suppl. 24","key":"10.1016\/j.jid.2019.03.1130_bib2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/jcb.240630503","article-title":"T-cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: history and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL)","volume":"63","author":"Bunn","year":"1996","journal-title":"J\u00a0Cell Biochem"},{"key":"10.1016\/j.jid.2019.03.1130_bib3","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1128\/MCB.22.13.4902-4913.2002","article-title":"Rad23 promotes the targeting of proteolytic substrates to the proteasome","volume":"22","author":"Chen","year":"2002","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jid.2019.03.1130_bib4","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.4049\/jimmunol.1302778","article-title":"A\u00a0novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3\/IL-10 pathway in APCs","volume":"193","author":"Cheng","year":"2014","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2019.03.1130_bib6","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.3324\/haematol.2013.085068","article-title":"STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model","volume":"98","author":"Couronn\u00e9","year":"2013","journal-title":"Haematologica"},{"key":"10.1016\/j.jid.2019.03.1130_bib7","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/ng.3442","article-title":"The mutational landscape of cutaneous T cell lymphoma and S\u00e9zary syndrome","volume":"47","author":"da Silva Almeida","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2019.03.1130_bib8","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1182\/blood-2006-06-025999","article-title":"Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)","volume":"109","author":"Duvic","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jid.2019.03.1130_bib9","first-page":"165","article-title":"Genetic characterization of S\u00e9zary\u2019s syndrome by conventional cytogenetics and cross-species color banding fluorescent in situ hybridization","volume":"89","author":"Espinet","year":"2004","journal-title":"Haematologica"},{"key":"10.1016\/j.jid.2019.03.1130_bib10","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.1158\/0008-5472.CAN-07-6091","article-title":"Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma","volume":"68","author":"Fantin","year":"2008","journal-title":"Cancer Res"},{"key":"10.1016\/j.jid.2019.03.1130_bib11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ccr.2008.12.001","article-title":"Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis","volume":"15","author":"Fotheringham","year":"2009","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jid.2019.03.1130_bib12","doi-asserted-by":"crossref","first-page":"175","DOI":"10.4161\/cbt.22957","article-title":"Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration","volume":"14","author":"Ierano","year":"2013","journal-title":"Cancer Biol Ther"},{"key":"10.1016\/j.jid.2019.03.1130_bib13","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/ng.3358","article-title":"Exome sequencing identifies somatic mutations of DDX3X in natural killer\/T-cell lymphoma","volume":"47","author":"Jiang","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2019.03.1130_bib14","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1128\/MCB.19.3.1910","article-title":"The significance of tetramerization in promoter recruitment by Stat5","volume":"19","author":"John","year":"1999","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jid.2019.03.1130_bib15","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1038\/ng.3415","article-title":"Integrated molecular analysis of adult T cell leukemia\/lymphoma","volume":"47","author":"Kataoka","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2019.03.1130_bib16","doi-asserted-by":"crossref","first-page":"6532","DOI":"10.1073\/pnas.0913912107","article-title":"HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy","volume":"107","author":"Khan","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2019.03.1130_bib17","doi-asserted-by":"crossref","first-page":"8470","DOI":"10.1038\/ncomms9470","article-title":"Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in S\u00e9zary syndrome","volume":"6","author":"Kiel","year":"2015","journal-title":"Nat Commun"},{"key":"10.1016\/j.jid.2019.03.1130_bib18","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1172\/JCI24826","article-title":"Immunopathogenesis and therapy of cutaneous T cell lymphoma","volume":"115","author":"Kim","year":"2005","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jid.2019.03.1130_bib19","doi-asserted-by":"crossref","first-page":"3357","DOI":"10.1091\/mbc.e03-11-0835","article-title":"Multiple interactions of Rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis","volume":"15","author":"Kim","year":"2004","journal-title":"Mol Biol Cell"},{"issue":"9","key":"10.1016\/j.jid.2019.03.1130_bib20","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.3390\/ijms19092708","article-title":"Protein tyrosine phosphatases as potential regulators of STAT3 signaling","volume":"19","author":"Kim","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jid.2019.03.1130_bib21","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1056\/NEJMoa1114885","article-title":"Somatic STAT3 mutations in large granular lymphocytic leukemia","volume":"366","author":"Koskela","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2019.03.1130_bib22","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/B978-0-12-418687-3.00018-5","article-title":"Transient mammalian cell transfection with polyethylenimine (PEI)","volume":"529","author":"Longo","year":"2013","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.jid.2019.03.1130_bib23","doi-asserted-by":"crossref","DOI":"10.1182\/blood.V124.21.3632.3632","article-title":"Inhibition of STAT3 reverses the resistance to histone deacetylase inhibitors induced by interleukin-6 in chronic lymphocytic leukemia cells","volume":"124","author":"Lu","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.jid.2019.03.1130_bib24","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1002\/j.1460-2075.1994.tb06452.x","article-title":"Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23","volume":"13","author":"Masutani","year":"1994","journal-title":"EMBO J"},{"key":"10.1016\/j.jid.2019.03.1130_bib25","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/leu.2011.198","article-title":"Constitutive activation of STAT3 in S\u00e9zary syndrome is independent of SHP-1","volume":"26","author":"McKenzie","year":"2012","journal-title":"Leukemia"},{"key":"10.1016\/j.jid.2019.03.1130_bib26","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1158\/2159-8290.CD-16-0330","article-title":"The genetic basis of hepatosplenic T-cell lymphoma","volume":"7","author":"McKinney","year":"2017","journal-title":"Cancer Discov"},{"key":"10.1016\/j.jid.2019.03.1130_bib27","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1084\/jem.20160894","article-title":"Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2","volume":"214","author":"Moffitt","year":"2017","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.jid.2019.03.1130_bib28","doi-asserted-by":"crossref","first-page":"15919","DOI":"10.1038\/s41598-017-15912-6","article-title":"TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity","volume":"7","author":"Mori","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jid.2019.03.1130_bib29","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1128\/MCB.16.5.2361","article-title":"Rad23 is required for transcription-coupled repair and efficient overall repair in Saccharomyces cerevisiae","volume":"16","author":"Mueller","year":"1996","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.jid.2019.03.1130_bib30","doi-asserted-by":"crossref","first-page":"95981","DOI":"10.18632\/oncotarget.21619","article-title":"Analysis of CTCL cell lines reveals important differences between mycosis fungoides\/S\u00e9zary syndrome vs. HTLV-1+ leukemic cell lines","volume":"8","author":"Netchiporouk","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.jid.2019.03.1130_bib31","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/cdd.2013.47","article-title":"A\u00a0regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors","volume":"20","author":"New","year":"2013","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jid.2019.03.1130_bib32","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1182\/blood-2017-02-768234","article-title":"Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E)","volume":"130","author":"Park","year":"2017","journal-title":"Blood"},{"key":"10.1016\/j.jid.2019.03.1130_bib33","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1084\/jem.20110283","article-title":"Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas","volume":"208","author":"Pilati","year":"2011","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.jid.2019.03.1130_bib34","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/2045-3701-2-23","article-title":"PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease","volume":"2","author":"Qu","year":"2012","journal-title":"Cell Biosci"},{"issue":"Pt. 8","key":"10.1016\/j.jid.2019.03.1130_bib35","first-page":"1281","article-title":"The JAK\/STAT signaling pathway","volume":"117","author":"Rawlings","year":"2015","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.jid.2019.03.1130_bib36","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1053\/j.gastro.2005.07.055","article-title":"STAT3 NH2-terminal acetylation is activated by the hepatic acute-phase response and required for IL-6 induction of angiotensinogen","volume":"129","author":"Ray","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jid.2019.03.1130_bib37","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1038\/jid.2009.306","article-title":"Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides","volume":"130","author":"Salgado","year":"2010","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2019.03.1130_bib38","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1038\/sj.leu.2403385","article-title":"In\u00a0vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3","volume":"18","author":"Sommer","year":"2004","journal-title":"Leukemia"},{"key":"10.1016\/j.jid.2019.03.1130_bib39","series-title":"WHO classification of tumours of haematopoietic and lymphoid tissues, 4th ed","author":"Swerdlow","year":"2017"},{"issue":"202","key":"10.1016\/j.jid.2019.03.1130_bib40","doi-asserted-by":"crossref","first-page":"ra85","DOI":"10.1126\/scisignal.2001637","article-title":"PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3","volume":"4","author":"Tanaka","year":"2011","journal-title":"Sci Signal"},{"issue":"7414","key":"10.1016\/j.jid.2019.03.1130_bib41","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/nature11232","article-title":"The accessible chromatin landscape of the human genome","volume":"489","author":"Thurman","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jid.2019.03.1130_bib42","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1111\/j.1476-5381.2010.01188.x","article-title":"The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells","volume":"162","author":"Tiffon","year":"2011","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jid.2019.03.1130_bib43","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/ng.3370","article-title":"Genomic analysis of mycosis fungoides and S\u00e9zary syndrome identifies recurrent alterations in TNFR2","volume":"47","author":"Ungewickell","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2019.03.1130_bib44","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1128\/aem.60.1.149-152.1994","article-title":"Detection of mycoplasma contamination in cell cultures by a mycoplasma group-specific PCR","volume":"60","author":"van Kuppeveld","year":"1994","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.jid.2019.03.1130_bib45","doi-asserted-by":"crossref","first-page":"342","DOI":"10.2478\/s11658-010-0008-2","article-title":"STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL","volume":"15","author":"Verma","year":"2010","journal-title":"Cell Mol Biol Lett"},{"key":"10.1016\/j.jid.2019.03.1130_bib46","doi-asserted-by":"crossref","first-page":"22","DOI":"10.4161\/trns.1.1.12201","article-title":"The Rad23 ubiquitin receptor, the proteasome and functional specificity in transcriptional control","volume":"1","author":"Wade","year":"2010","journal-title":"Transcription"},{"issue":"5 Suppl. 1","key":"10.1016\/j.jid.2019.03.1130_bib47","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jid.2016.02.051","article-title":"Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome","volume":"136","author":"Walker","year":"2016","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2019.03.1130_bib48","doi-asserted-by":"crossref","first-page":"11528","DOI":"10.1074\/jbc.M413930200","article-title":"Activation of Stat3 sequence-specific DNA binding and transcription by p300\/CREB-binding protein-mediated acetylation","volume":"280","author":"Wang","year":"2005","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jid.2019.03.1130_bib49","first-page":"7757","article-title":"The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function","volume":"13","author":"Watkins","year":"1993","journal-title":"Mol Cell Biol"},{"issue":"11","key":"10.1016\/j.jid.2019.03.1130_bib50","doi-asserted-by":"crossref","first-page":"e49567","DOI":"10.1371\/journal.pone.0049567","article-title":"The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination","volume":"7","author":"Wei","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jid.2019.03.1130_bib51","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1200\/JCO.2010.28.9066","article-title":"Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma","volume":"28","author":"Whittaker","year":"2010","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.jid.2019.03.1130_bib52","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/ncb1001-939","article-title":"Proteins containing the UBA domain are able to bind to multi-ubiquitin chains","volume":"3","author":"Wilkinson","year":"2001","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jid.2019.03.1130_bib53","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1182\/blood-2016-02-699843","article-title":"Candidate driver genes involved in genome maintenance and DNA repair in S\u00e9zary syndrome","volume":"127","author":"Woollard","year":"2016","journal-title":"Blood"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X19313405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X19313405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T21:43:23Z","timestamp":1762206203000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X19313405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":52,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S0022202X19313405"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2019.03.1130","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contribution of STAT3 and RAD23B in Primary S\u00e9zary Cells to Histone Deacetylase Inhibitor FK228 Resistance","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2019.03.1130","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}