{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T07:12:42Z","timestamp":1772262762039,"version":"3.50.1"},"reference-count":52,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["2015YZB22C-002 LS6"],"award-info":[{"award-number":["2015YZB22C-002 LS6"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["B16J15001970001"],"award-info":[{"award-number":["B16J15001970001"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004434","name":"Universit\u00c3\u00a0 degli Studi di Firenze","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004434","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005969","name":"Universit\u00c3\u00a0 di Bologna","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005969","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.jid.2019.03.1144","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T12:59:19Z","timestamp":1554814759000},"page":"2125-2133.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Effects of Parvovirus B19 In\u00a0Vitro Infection on Monocytes from Patients with Systemic Sclerosis: Enhanced Inflammatory Pathways by Caspase-1 Activation and Cytokine Production"],"prefix":"10.1016","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0184-4785","authenticated-orcid":false,"given":"Krystyna","family":"Zakrzewska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1683-9540","authenticated-orcid":false,"given":"Rosaria","family":"Arvia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-4646","authenticated-orcid":false,"given":"Maria Gabriella","family":"Torcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0386-590X","authenticated-orcid":false,"given":"Ann Maria","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2642-1706","authenticated-orcid":false,"given":"Michele","family":"Tanturli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2237-6765","authenticated-orcid":false,"given":"Giuseppe","family":"Castronovo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5702-3850","authenticated-orcid":false,"given":"Gianluca","family":"Sighinolfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0041-3695","authenticated-orcid":false,"given":"Dilia","family":"Giuggioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0840-5817","authenticated-orcid":false,"given":"Clodoveo","family":"Ferri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2019.03.1144_bib1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1006\/viro.1994.1460","article-title":"The structure of human parvovirus B19 at 8 A resolution","volume":"203","author":"Agbandje","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.jid.2019.03.1144_bib2","doi-asserted-by":"crossref","first-page":"pii:E508","DOI":"10.3390\/v10090508","article-title":"A\u00a0paradigmatic interplay between human cytomegalovirus and host immune system: possible involvement of viral antigen-driven CD8+ T cell responses in systemic sclerosis","volume":"10","author":"Arcangeletti","year":"2018","journal-title":"Viruses"},{"key":"10.1016\/j.jid.2019.03.1144_bib3","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1002\/art.30568","article-title":"The inflammasome activating caspase 1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis","volume":"63","author":"Artlett","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jid.2019.03.1144_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jviromet.2017.04.003","article-title":"Droplet digital PCR (ddPCR) vs quantitative real-time PCR (qPCR) approach for detection and quantification of Merkel cell polyomavirus (MCPyV) DNA in formalin fixed paraffin embedded (FFPE) cutaneous biopsies","volume":"246","author":"Arvia","year":"2017","journal-title":"J\u00a0Virol Methods"},{"key":"10.1016\/j.jid.2019.03.1144_bib5","doi-asserted-by":"crossref","first-page":"14502","DOI":"10.1074\/jbc.M312630200","article-title":"Interfacial enzymology of parvovirus phospholipases A2","volume":"279","author":"Canaan","year":"2004","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jid.2019.03.1144_bib6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.intimp.2014.08.002","article-title":"THP-1 cell line: an in\u00a0vitro cell model for immune modulation approach","volume":"23","author":"Chanput","year":"2014","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jid.2019.03.1144_bib7","first-page":"3364","article-title":"Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult-onset Still's disease","volume":"17","author":"Chen","year":"2018","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jid.2019.03.1144_bib8","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/nri2873","article-title":"Sterile inflammation: sensing and reacting to damage","volume":"10","author":"Chen","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jid.2019.03.1144_bib9","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1111\/j.1462-5822.2011.01622.x","article-title":"Plasmodium falciparum soluble extracts potentiate the suppressive function of polyclonal T regulatory cells through activation of TGF\u03b2-mediated signals","volume":"13","author":"Clemente","year":"2011","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.jid.2019.03.1144_bib10","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1128\/IAI.01226-12","article-title":"Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes","volume":"81","author":"Clemente","year":"2013","journal-title":"Infect Immun"},{"key":"10.1016\/j.jid.2019.03.1144_bib11","first-page":"1281","article-title":"Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis","volume":"22","author":"Clements","year":"1995","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.jid.2019.03.1144_bib12","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.imlet.2018.03.011","article-title":"Different profile of cytokine production in patients with systemic sclerosis and association with clinical manifestations","volume":"198","author":"Dantas","year":"2018","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jid.2019.03.1144_bib13","doi-asserted-by":"crossref","first-page":"8110","DOI":"10.4049\/jimmunol.0901031","article-title":"Signaling crosstalk during sequential TLR4 and TLR9 activation amplifies the inflammatory response of mouse macrophages","volume":"183","author":"De Nardo","year":"2009","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2019.03.1144_bib14","first-page":"47","article-title":"The autoinflammatory side of systemic sclerosis","volume":"17","author":"De Santis","year":"2015","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.jid.2019.03.1144_bib15","doi-asserted-by":"crossref","first-page":"e1000480","DOI":"10.1371\/journal.ppat.1000480","article-title":"Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome","volume":"5","author":"Delaloye","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.jid.2019.03.1144_bib16","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1128\/JVI.76.4.2014-2018.2002","article-title":"The VP1 unique region of parvovirus B19 and its constituent phospholipase A2-like activity","volume":"76","author":"Dorsch","year":"2002","journal-title":"J\u00a0Virol"},{"key":"10.1016\/j.jid.2019.03.1144_bib17","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1002\/art.23451","article-title":"Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma","volume":"58","author":"Duan","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jid.2019.03.1144_bib18","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/jid.2013.423","article-title":"Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma","volume":"134","author":"Farina","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2019.03.1144_bib19","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13075-017-1237-9","article-title":"Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes","volume":"19","author":"Farina","year":"2017","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jid.2019.03.1144_bib20","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/imm.12200","article-title":"Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA","volume":"141","author":"Fattal","year":"2014","journal-title":"Immunology"},{"key":"10.1016\/j.jid.2019.03.1144_bib21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.semarthrit.2018.06.009","article-title":"High serum levels of silica nanoparticles in systemic sclerosis patients with occupational exposure: possible pathogenetic role in disease phenotypes","volume":"48","author":"Ferri","year":"2018","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.jid.2019.03.1144_bib22","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1002\/art.10346","article-title":"Parvovirus B19 infection of cultured skin fibroblasts from systemic sclerosis patients: comment on the article by Ray et\u00a0al","volume":"46","author":"Ferri","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jid.2019.03.1144_bib23","first-page":"267","article-title":"Parvovirus B19 and systemic sclerosis","volume":"17","author":"Ferri","year":"1999","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.jid.2019.03.1144_bib24","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.autrev.2014.08.029","article-title":"Systemic sclerosis evolution of disease pathomorphosis and survival. Our experience on Italian patients\u2019 population and review of the literature","volume":"13","author":"Ferri","year":"2014","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jid.2019.03.1144_bib25","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/00005792-200203000-00004","article-title":"Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients","volume":"81","author":"Ferri","year":"2002","journal-title":"Medicine"},{"key":"10.1016\/j.jid.2019.03.1144_bib26","first-page":"3786","article-title":"IL-1R1\/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice","volume":"117","author":"Gasse","year":"2007","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jid.2019.03.1144_bib27","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/ni.1861","article-title":"Influenza virus activates inflammasomes via its intracellular M2 ion channel","volume":"11","author":"Ichinohe","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2019.03.1144_bib28","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1006\/viro.1995.1418","article-title":"Most of the VP1 unique region of B19 parvovirus is on the capsid surface","volume":"211","author":"Kawase","year":"1995","journal-title":"Virology"},{"key":"10.1016\/j.jid.2019.03.1144_bib29","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1136\/jclinpath-2015-203455","article-title":"The role of parvovirus B19 in the pathogenesis of autoimmunity and autoimmune disease","volume":"69","author":"Kerr","year":"2016","journal-title":"J\u00a0Clin Pathol"},{"key":"10.1016\/j.jid.2019.03.1144_bib30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5301\/jsrd.5000231","article-title":"Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis","volume":"2","author":"Khanna","year":"2017","journal-title":"J\u00a0Scleroderma Relat Disord"},{"key":"10.1016\/j.jid.2019.03.1144_bib31","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1002\/jmv.22066","article-title":"Attempt to classify the clinical impact of DNA viruses according to the ability to activate the innate immune system","volume":"83","author":"Lanini","year":"2011","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.jid.2019.03.1144_bib32","series-title":"Cecil textbook of medicine","first-page":"1530","article-title":"Systemic sclerosis (scleroderma)","author":"Le Roy","year":"1992"},{"key":"10.1016\/j.jid.2019.03.1144_bib33","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1086\/499599","article-title":"Activation of synoviocytes by the secreted phospholipase A2 motif in the VP1-unique region of parvovirus B19 minor capsid protein","volume":"193","author":"Lu","year":"2006","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.jid.2019.03.1144_bib34","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1371\/journal.pmed.0030002","article-title":"Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: a gene array approach","volume":"3","author":"Lunardi","year":"2006","journal-title":"PLoS Med"},{"key":"10.1016\/j.jid.2019.03.1144_bib35","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1002\/(SICI)1521-4141(199803)28:03<936::AID-IMMU936>3.0.CO;2-X","article-title":"Chronic parvovirus B19 infection induces the production of anti-virus antibodies with autoantigen binding properties","volume":"28","author":"Lunardi","year":"1998","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jid.2019.03.1144_bib36","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.0303-6987.2003.0143.x","article-title":"Parvoviral infection of endothelial cells and stromal \ufb01broblasts: a possible pathogenetic role in scleroderma","volume":"31","author":"Magro","year":"2004","journal-title":"J\u00a0Cutan Pathol"},{"key":"10.1016\/j.jid.2019.03.1144_bib37","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.virol.2005.09.040","article-title":"Human parvovirus B19 infection of monocytic cell line U937 and antibody-dependent enhancement","volume":"345","author":"Munakata","year":"2006","journal-title":"Virology"},{"key":"10.1016\/j.jid.2019.03.1144_bib38","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nature06664","article-title":"The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response","volume":"452","author":"Muruve","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jid.2019.03.1144_bib39","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1006\/viro.2002.1585","article-title":"Identification and characterization of a second novel human erythrovirus variant, A6","volume":"301","author":"Nguyen","year":"2002","journal-title":"Virology"},{"key":"10.1016\/j.jid.2019.03.1144_bib40","doi-asserted-by":"crossref","first-page":"7450","DOI":"10.1073\/pnas.0602259103","article-title":"Bioportfolio: lifelong persistence of variant and prototypic erythrovirus DNA genomes in human tissue","volume":"103","author":"Norja","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2019.03.1144_bib41","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1042\/CS20130367","article-title":"Innate immunity in systemic sclerosis pathogenesis","volume":"126","author":"O\u2019Reilly","year":"2014","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.jid.2019.03.1144_bib42","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.imlet.2017.09.001","article-title":"Toll Like Receptors in systemic sclerosis: an emerging target","volume":"195","author":"O\u2019Reilly","year":"2018","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jid.2019.03.1144_bib43","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/j.0007-0963.2004.05930.x","article-title":"Increased prevalence of human parvovirus B19 DNA in systemic sclerosis skin","volume":"150","author":"Ohtsuka","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2019.03.1144_bib44","doi-asserted-by":"crossref","first-page":"pii:E360","DOI":"10.3390\/ijms20020360","article-title":"Dual role of triptolide in interrupting the NLRP3 inflammasome pathway to attenuate cardiac fibrosis","volume":"20","author":"Pan","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jid.2019.03.1144_bib45","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/S1357-2725(98)00081-8","article-title":"Interleukin-1","volume":"30","author":"Stylianou","year":"1998","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.jid.2019.03.1144_bib46","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jviromet.2015.03.006","article-title":"A\u00a0new quantitative PCR for human parvovirus B19 genotypes","volume":"218","author":"Toppinen","year":"2015","journal-title":"J\u00a0Virol Methods"},{"key":"10.1016\/j.jid.2019.03.1144_bib47","doi-asserted-by":"crossref","first-page":"e0175053","DOI":"10.1371\/journal.pone.0175053","article-title":"Epstein-Barr virus infection-induced inflammasome activation in human monocytes","volume":"12","author":"Torii","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jid.2019.03.1144_bib48","first-page":"1747","article-title":"2013 Classification criteria for systemic sclerosis: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"72","author":"van den Hoogen","year":"2013","journal-title":"Arthritis Rheum Dis"},{"key":"10.1016\/j.jid.2019.03.1144_bib49","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1056\/NEJMra030840","article-title":"Parvovirus B19","volume":"350","author":"Young","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2019.03.1144_bib50","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S1534-5807(01)00031-4","article-title":"A\u00a0viral phospholipase A2 is required for parvovirus infectivity","volume":"1","author":"Z\u00e1dori","year":"2001","journal-title":"Dev Cell"},{"issue":"1\u20132","key":"10.1016\/j.jid.2019.03.1144_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.virusres.2005.05.003","article-title":"Human parvovirus B19 experimental infection in human fibroblasts and endothelial cells cultures","volume":"114","author":"Zakrzewska","year":"2005","journal-title":"Virus Res"},{"key":"10.1016\/j.jid.2019.03.1144_bib52","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13071-018-3223-8","article-title":"NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-\u03baB","volume":"12","author":"Zhang","year":"2019","journal-title":"Parasit Vectors"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1931471X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X1931471X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T21:43:17Z","timestamp":1762206197000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X1931471X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":52,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S0022202X1931471X"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2019.03.1144","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of Parvovirus B19 In\u00a0Vitro Infection on Monocytes from Patients with Systemic Sclerosis: Enhanced Inflammatory Pathways by Caspase-1 Activation and Cytokine Production","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2019.03.1144","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}