{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T21:34:37Z","timestamp":1758317677717,"version":"3.44.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.jid.2020.10.005","type":"journal-article","created":{"date-parts":[[2021,3,19]],"date-time":"2021-03-19T18:11:03Z","timestamp":1616177463000},"page":"718-721","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7366-3233","authenticated-orcid":false,"given":"Ken","family":"Okamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8732-1293","authenticated-orcid":false,"given":"Manuel","family":"Garber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7815-6430","authenticated-orcid":false,"given":"John E.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2020.10.005_bib1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1034\/j.1600-0749.2003.00032.x","article-title":"Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families","volume":"16","author":"Alkhateeb","year":"2003","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.jid.2020.10.005_bib2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jpeds.2016.09.008","article-title":"Chemical leukoderma associated with methylphenidate transdermal system: data from the US Food and Drug Administration Adverse Event Reporting System","volume":"180","author":"Cheng","year":"2017","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.jid.2020.10.005_bib3","first-page":"192","article-title":"FTO obesity variant and adipocyte browning in humans","volume":"374","author":"Claussnitzer","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2020.10.005_bib4","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.det.2016.11.010","article-title":"Depigmentation therapies\u00a0for vitiligo","volume":"35","author":"Grimes","year":"2017","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.jid.2020.10.005_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.det.2016.11.006","article-title":"Chemical-induced vitiligo","volume":"35","author":"Harris","year":"2017","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.jid.2020.10.005_bib6","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/s41467-019-08337-4","article-title":"Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression","volume":"10","author":"Jin","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.jid.2020.10.005_bib7","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jid.2020.07.029","article-title":"Familial risk of vitiligo among first-degree relatives and spouses: a population-based cohort study in Korea","volume":"141","author":"Kim","year":"2021","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2020.10.005_bib8","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1111\/j.1365-4632.2011.05377.x","article-title":"A\u00a0review of the worldwide prevalence of vitiligo in children\/adolescents and adults","volume":"51","author":"Kr\u00fcger","year":"2012","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jid.2020.10.005_bib9","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3349\/ymj.2015.56.3.719","article-title":"Prevalence of vitiligo and associated comorbidities in Korea","volume":"56","author":"Lee","year":"2015","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.jid.2020.10.005_bib10","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1001\/archderm.1993.01680290066010","article-title":"Pattern of familial aggregation of vitiligo","volume":"129","author":"Majumder","year":"1993","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.jid.2020.10.005_bib11","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/pcmr.12904","article-title":"Genome-wide association study identifies CDH13 as a susceptibility gene\u00a0for rhododendrol-induced leukoderma","volume":"33","author":"Okamura","year":"2020","journal-title":"Pigment Cell Melanoma Res"},{"key":"10.1016\/j.jid.2020.10.005_bib12","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nature13138","article-title":"Obesity-associated variants within FTO form long-range functional connections with IRX3","volume":"507","author":"Smemo","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jid.2020.10.005_bib13","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.det.2016.11.013","article-title":"Genetics of vitiligo","volume":"35","author":"Spritz","year":"2017","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.jid.2020.10.005_bib14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/1523-1747.ep12319351","article-title":"Mutational analysis of copper binding by human tyrosinase","volume":"109","author":"Spritz","year":"1997","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2020.10.005_bib15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.molcel.2020.09.005","article-title":"High-resolution mapping of multiway enhancer-promoter interactions regulating pathogen detection","volume":"80","author":"Vangala","year":"2020","journal-title":"Mol Cell"},{"key":"10.1016\/j.jid.2020.10.005_bib16","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/pcmr.12402","article-title":"Use of permanent hair dyes and risk of vitiligo in women","volume":"28","author":"Wu","year":"2015","journal-title":"Pigment Cell Melanoma Res"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X20321916?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X20321916?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T17:21:04Z","timestamp":1758302464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X20321916"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0022202X20321916"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2020.10.005","relation":{},"ISSN":["0022-202X"],"issn-type":[{"type":"print","value":"0022-202X"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2020.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2020.07.029","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}