{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:59:28Z","timestamp":1790848768146,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["1F31AR079902-01A1"],"award-info":[{"award-number":["1F31AR079902-01A1"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011594","name":"Penn State College of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011594","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.jid.2022.09.656","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:45:26Z","timestamp":1666140326000},"page":"578-587.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["AIRE Deficiency Leads to the Development of Alopecia Areata\u2012Like Lesions in Mice"],"prefix":"10.1016","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6441-4753","authenticated-orcid":false,"given":"Natella","family":"Maglakelidze","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5426-4285","authenticated-orcid":false,"given":"Ting","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5368-1872","authenticated-orcid":false,"given":"Robert P.","family":"Feehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2827-1828","authenticated-orcid":false,"given":"Ryan P.","family":"Hobbs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2022.09.656_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nri.2016.9","article-title":"AIRE expands: new roles in immune tolerance and beyond","volume":"16","author":"Anderson","year":"2016","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib2","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1126\/science.1075958","article-title":"Projection of an immunological self shadow within the thymus by the Aire protein","volume":"298","author":"Anderson","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.jid.2022.09.656_bib3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1159\/000485080","article-title":"Immune privilege collapse and alopecia development: is stress a factor","volume":"4","author":"Azzawi","year":"2018","journal-title":"Skin Appendage Disord"},{"key":"10.1016\/j.jid.2022.09.656_bib4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/exd.14155","article-title":"Hair follicle immune privilege and its collapse in alopecia areata","volume":"29","author":"Bertolini","year":"2020","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0094260","article-title":"Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata","volume":"9","author":"Bertolini","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jid.2022.09.656_bib6","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/ni.2536","article-title":"Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation","volume":"14","author":"Best","year":"2013","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib7","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1080\/15384101.2016.1241918","article-title":"Expression and prognostic significance of the autoimmune regulator gene in breast cancer cells","volume":"15","author":"Bianchi","year":"2016","journal-title":"Cell Cycle"},{"key":"10.1016\/j.jid.2022.09.656_bib8","first-page":"137424","article-title":"A\u00a0transcriptomic map of murine and human alopecia areata","volume":"5","author":"Borcherding","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.jid.2022.09.656_bib9","first-page":"154","article-title":"Interleukin-2 receptor alpha-chain expression in patients with alopecia areata","volume":"12","author":"Brajac","year":"2004","journal-title":"Acta Dermatovenerol Croat"},{"key":"10.1016\/j.jid.2022.09.656_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/science.aay5731","article-title":"Aberrant type 1 immunity drives susceptibility to mucosal fungal infections","volume":"371","author":"Break","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.jid.2022.09.656_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1002002","article-title":"Macrophages contribute to the cyclic activation of adult hair follicle stem cells","volume":"12","author":"Castellana","year":"2014","journal-title":"PLoS Biol"},{"key":"10.1016\/j.jid.2022.09.656_bib12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.autrev.2017.10.017","article-title":"Beyond APECED: an update on the role of the autoimmune regulator gene (AIRE) in physiology and disease","volume":"17","author":"Conteduca","year":"2018","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jid.2022.09.656_bib13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/77793","article-title":"Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages","volume":"1","author":"Diefenbach","year":"2000","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000024","article-title":"Defining the role of the MHC in autoimmunity: a review and pooled analysis","volume":"4","author":"Fernando","year":"2008","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jid.2022.09.656_bib15","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1365-2133.2006.07377.x","article-title":"Interferon-gamma-deficient mice are resistant to the development of alopecia areata","volume":"155","author":"Freyschmidt-Paul","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib16","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1056\/NEJMra1103442","article-title":"Alopecia areata","volume":"366","author":"Gilhar","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2022.09.656_bib17","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.0022-202X.2004.23580.x","article-title":"Alopecia areata induced in C3H\/HeJ mice by interferon-gamma: evidence for loss of immune privilege","volume":"124","author":"Gilhar","year":"2005","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib18","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/jid.2012.365","article-title":"Autoimmune disease induction in a healthy human organ: a humanized mouse model of alopecia areata","volume":"133","author":"Gilhar","year":"2013","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib19","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1172\/JCI31942","article-title":"Lymphocytes, neuropeptides, and genes involved in alopecia areata","volume":"117","author":"Gilhar","year":"2007","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jid.2022.09.656_bib20","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.autrev.2016.03.008","article-title":"Alopecia areata: animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies","volume":"15","author":"Gilhar","year":"2016","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jid.2022.09.656_bib21","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1172\/JCI551","article-title":"Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice","volume":"101","author":"Gilhar","year":"1998","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jid.2022.09.656_bib22","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/ng.3355","article-title":"Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes","volume":"47","author":"Hobbs","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2022.09.656_bib23","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.3389\/fimmu.2019.02342","article-title":"Targeting the Janus kinase family in autoimmune skin diseases","volume":"10","author":"Howell","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib24","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1365-2567.2000.00073.x","article-title":"T-cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling","volume":"100","author":"Hoyne","year":"2000","journal-title":"Immunology"},{"key":"10.1016\/j.jid.2022.09.656_bib25","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.4049\/jimmunol.0802124","article-title":"Aire-deficient C57BL\/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype","volume":"182","author":"Hubert","year":"2009","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib26","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1038\/sj.jid.5701183","article-title":"Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack","volume":"128","author":"Ito","year":"2008","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib27","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ebiom.2015.02.015","article-title":"Reversal of alopecia areata following treatment with the JAK1\/2 inhibitor baricitinib","volume":"2","author":"Jabbari","year":"2015","journal-title":"EBiomedicine"},{"key":"10.1016\/j.jid.2022.09.656_bib28","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/exd.13060","article-title":"Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers","volume":"25","author":"Jabbari","year":"2016","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nri2136-c1","article-title":"Does the deficiency of Aire in mice really resemble human APECED?","volume":"7","author":"Kek\u00e4l\u00e4inen","year":"2007","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib30","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s10875-015-0176-y","article-title":"Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy","volume":"35","author":"Kisand","year":"2015","journal-title":"J\u00a0Clin Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib31","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.ajpath.2010.12.007","volume":"178","author":"Kumar","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jid.2022.09.656_bib32","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1046\/j.0022-202x.2001.01368.x","article-title":"Patterns of proliferation and apoptosis during murine hair follicle morphogenesis","volume":"116","author":"Magerl","year":"2001","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib33","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/sj.jidsp.5640211","article-title":"Spontaneous alopecia areata-like hair loss in one congenic and seven inbred laboratory mouse strains","volume":"4","author":"McElwee","year":"1999","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib34","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1111\/j.0022-202X.2005.23692.x","article-title":"Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)\/CD25(\u2212) cells promote systemic alopecia areata and CD4(+)\/CD25(+) cells blockade disease onset in the C3H\/HeJ mouse model","volume":"124","author":"McElwee","year":"2005","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib35","first-page":"1077","article-title":"Evidence that the bulge region is a site of relative immune privilege in human hair follicles","volume":"159","author":"Meyer","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.0022-202x.2001.01377.x","article-title":"A\u00a0comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages","volume":"117","author":"M\u00fcller-R\u00f6ver","year":"2001","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib37","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.immuni.2012.03.014","article-title":"JAK and STAT signaling molecules in immunoregulation and immune-mediated disease","volume":"36","author":"O\u2019Shea","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.jid.2022.09.656_bib38","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.immuni.2015.04.021","article-title":"Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases","volume":"42","author":"Oftedal","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.jid.2022.09.656_bib39","doi-asserted-by":"crossref","first-page":"874","DOI":"10.4049\/jimmunol.1701318","article-title":"Breakdown of immune tolerance in AIRE-deficient rats induces a severe autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy-like autoimmune disease","volume":"201","author":"Ossart","year":"2018","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib40","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1038\/jidsymp.2013.7","article-title":"The role of hair follicle immune privilege collapse in alopecia areata: status and perspectives","volume":"16","author":"Paus","year":"2013","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib41","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1016\/j.jisp.2017.10.014","article-title":"Hair follicle immune privilege revisited: the key to alopecia areata management","volume":"19","author":"Paus","year":"2018","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib42","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1046\/j.1087-0024.2003.00807.x","article-title":"The hair follicle and immune privilege","volume":"8","author":"Paus","year":"2003","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib43","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.it.2004.09.014","article-title":"A\u00a0\u2018hairy\u2019 privilege","volume":"26","author":"Paus","year":"2005","journal-title":"Trends Immunol"},{"key":"10.1016\/j.jid.2022.09.656_bib44","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature09114","article-title":"Genome-wide association study in alopecia areata implicates both innate and adaptive immunity","volume":"466","author":"Petukhova","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.jid.2022.09.656_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.11","article-title":"Alopecia areata","volume":"3","author":"Pratt","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jid.2022.09.656_bib46","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/exd.13046","article-title":"A\u00a0primer for studying cell cycle dynamics of the human hair follicle","volume":"25","author":"Purba","year":"2016","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib47","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nrd.2017.201","article-title":"JAK inhibition as a therapeutic strategy for immune and inflammatory diseases [published correction appears in Nat Rev Drug Discov 2017;17:78","volume":"16","author":"Schwartz","year":"2017","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.jid.2022.09.656_bib48","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/1523-1747.ep12382416","article-title":"Alopecia areata in aging C3H\/HeJ mice","volume":"102","author":"Sundberg","year":"1994","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2022.09.656_bib49","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1046\/j.1087-0024.2003.00804.x","article-title":"Mouse alopecia areata models: an array of data on mechanisms and genetics","volume":"8","author":"Sundberg","year":"2003","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib50","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/jidsymp.2015.35","article-title":"Animal models for alopecia areata: what and where?","volume":"17","author":"Sundberg","year":"2015","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.jid.2022.09.656_bib51","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1034\/j.1399-0039.2002.600604.x","article-title":"Role of the autoimmune regulator (AIRE) gene in alopecia areata: strong association of a potentially functional AIRE polymorphism with alopecia universalis","volume":"60","author":"Tazi-Ahnini","year":"2002","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jid.2022.09.656_bib52","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.2147\/DDDT.S172638","article-title":"Role of Janus kinase inhibitors in the treatment of alopecia areata","volume":"12","author":"Triyangkulsri","year":"2018","journal-title":"Drug Des Devel Ther"},{"key":"10.1016\/j.jid.2022.09.656_bib53","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s004030050239","article-title":"Hair cycle-dependent changes in the gene expression and protein content of transforming factor \u03b21 and \u03b23 in murine skin","volume":"289","author":"Welker","year":"1997","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jid.2022.09.656_bib54","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1399-0039.2007.00992.x","article-title":"Genetic analysis of autoimmune regulator haplotypes in alopecia areata","volume":"71","author":"Wengraf","year":"2008","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jid.2022.09.656_bib55","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/nm.3645","article-title":"Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition","volume":"20","author":"Xing","year":"2014","journal-title":"Nat Med"},{"key":"10.1016\/j.jid.2022.09.656_bib56","doi-asserted-by":"crossref","first-page":"a006957","DOI":"10.1101\/cshperspect.a006957","article-title":"T-cell tolerance: central and peripheral","volume":"4","author":"Xing","year":"2012","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.jid.2022.09.656_bib57","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1084\/jem.20080046","article-title":"Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance","volume":"205","author":"Yano","year":"2008","journal-title":"J\u00a0Exp Med"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X22026422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X22026422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T17:31:06Z","timestamp":1758303066000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X22026422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S0022202X22026422"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2022.09.656","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AIRE Deficiency Leads to the Development of Alopecia Areata\u2012Like Lesions in Mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2022.09.656","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}