{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T21:49:33Z","timestamp":1778795373590,"version":"3.51.4"},"reference-count":44,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King&apos;s College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000770","name":"University of Manchester","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000770","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/L011808\/1"],"award-info":[{"award-number":["MR\/L011808\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013126","name":"Psoriasis Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013126","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014461","name":"NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust\/Institute of Cancer Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014461","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019418","name":"NIHR Maudsley Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011110","name":"UCB","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011110","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000276","name":"Department of Health and Social Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009360","name":"King\u2019s College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009360","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000545","name":"British Association of Dermatologists","doi-asserted-by":"publisher","award":["RG2\/10"],"award-info":[{"award-number":["RG2\/10"]}],"id":[{"id":"10.13039\/501100000545","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.jid.2023.01.021","type":"journal-article","created":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T03:19:14Z","timestamp":1676431154000},"page":"1470-1478.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Atopic Polygenic Risk Score Is Associated with Paradoxical Eczema Developing in Patients with Psoriasis Treated with Biologics"],"prefix":"10.1016","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2094-0556","authenticated-orcid":false,"given":"Ali","family":"Al-Janabi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-6974","authenticated-orcid":false,"given":"Steve","family":"Eyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2680-750X","authenticated-orcid":false,"given":"Amy C.","family":"Foulkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7126-7157","authenticated-orcid":false,"given":"Adnan R.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1805-6278","authenticated-orcid":false,"given":"Nick","family":"Dand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4295-7292","authenticated-orcid":false,"given":"Ekaterina","family":"Burova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8512-3039","authenticated-orcid":false,"given":"Bernadette","family":"DeSilva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1589-7469","authenticated-orcid":false,"given":"Areti","family":"Makrygeorgou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6706-0804","authenticated-orcid":false,"given":"Emily","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9918-1144","authenticated-orcid":false,"given":"Catherine H.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-4427","authenticated-orcid":false,"given":"Christopher E.M.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6805-6014","authenticated-orcid":false,"given":"Andrew P.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2918-6481","authenticated-orcid":false,"given":"Richard B.","family":"Warren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2023.01.021_bib1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/bjd.21098","article-title":"RF03: risk factors for paradoxical eczema in patients with psoriasis on biologics: a nested case\u2013control study","volume":"187","author":"Al-Janabi","year":"2022","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib2","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1111\/jdv.16246","article-title":"Phenotypic switch to eczema in patients receiving biologics for plaque psoriasis: a systematic review","volume":"34","author":"Al-Janabi","year":"2020","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jid.2023.01.021_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jaci.2021.05.034","article-title":"Polygenic prediction of atopic dermatitis improves with atopic training and filaggrin factors","volume":"149","author":"Arehart","year":"2022","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052935","article-title":"Quality of life and work productivity impairment among psoriasis patients: findings from the National Psoriasis Foundation survey data 2003\u20132011","volume":"7","author":"Armstrong","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jid.2023.01.021_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4049\/jimmunol.172.1.61","article-title":"Sustained IL-12 signaling is required for Th1 development","volume":"172","author":"Athie-Morales","year":"2004","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib6","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ajhg.2014.12.004","article-title":"Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms","volume":"96","author":"Baurecht","year":"2015","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib7","first-page":"1122","article-title":"TNF-anti-TNF immune complexes inhibit IL-12\/IL-23 secretion by inflammatory macrophages via an Fc-dependent mechanism","volume":"12","author":"Bloemendaal","year":"2018","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.jid.2023.01.021_bib8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-2133.2012.10835.x","article-title":"The British Association of Dermatologists\u2019 Biologic Interventions Register (BADBIR): design, methodology and objectives","volume":"166","author":"Burden","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib9","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.3390\/ijms18122526","article-title":"The genetic basis of psoriasis","volume":"18","author":"Capon","year":"2017","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jid.2023.01.021_bib10","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.4161\/cc.9.8.11197","article-title":"Netrin-1 role in angiogenesis: to be or not to be a pro-angiogenic factor?","volume":"9","author":"Castets","year":"2010","journal-title":"Cell Cycle"},{"key":"10.1016\/j.jid.2023.01.021_bib11","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1016\/j.jaip.2020.06.064","article-title":"Mixed profile of cytokines in paradoxical eczematous eruptions associated with anti-IL-17 therapy","volume":"8","author":"Chicharro","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.jid.2023.01.021_bib12","doi-asserted-by":"crossref","first-page":"giz082","DOI":"10.1093\/gigascience\/giz082","article-title":"PRSice-2: polygenic Risk Score software for biobank-scale data","volume":"8","author":"Choi","year":"2019","journal-title":"GigaScience"},{"key":"10.1016\/j.jid.2023.01.021_bib13","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1002\/ski2.29","article-title":"Can atopic eczema and psoriasis coexist? A systematic review and meta-analysis","volume":"1","author":"Cunliffe","year":"2021","journal-title":"Skin Health Dis"},{"key":"10.1016\/j.jid.2023.01.021_bib14","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1016\/j.jaci.2018.11.038","article-title":"HLA-C\u221706:02 genotype is a predictive biomarker of biologic treatment response in psoriasis","volume":"143","author":"Dand","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib15","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/ng.3656","article-title":"Next-generation genotype imputation service and methods","volume":"48","author":"Das","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib16","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jaad.2013.10.010","article-title":"Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis","volume":"70","author":"Eichenfield","year":"2014","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib17","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1056\/NEJMoa1104200","article-title":"Mutual antagonism of T cells causing psoriasis and atopic eczema","volume":"365","author":"Eyerich","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jid.2023.01.021_bib18","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1038\/ng.3985","article-title":"Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology","volume":"49","author":"Ferreira","year":"2017","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib19","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1046\/j.1523-1747.1999.00509.x","article-title":"Evidence for a novel glutamate-mediated signaling pathway in keratinocytes","volume":"112","author":"Genever","year":"1999","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib20","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/ng.2653","article-title":"The Genotype-Tissue Expression (GTEx) project","volume":"45","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib21","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/0190-9622(95)91336-X","article-title":"Disease concomitance in psoriasis","volume":"32","author":"Henseler","year":"1995","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib22","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/bjd.13908","article-title":"Demographics and disease characteristics of patients with psoriasis enrolled in the British Association of Dermatologists Biologic Interventions Register","volume":"173","author":"Iskandar","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib23","doi-asserted-by":"crossref","first-page":"888","DOI":"10.3389\/fimmu.2018.00888","article-title":"Tuning the cytokine responses: an update on interleukin (IL)-4 and IL-13 receptor complexes","volume":"9","author":"Junttila","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib25","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13073-020-00742-5","article-title":"Polygenic risk scores: from research tools to clinical instruments","volume":"12","author":"Lewis","year":"2020","journal-title":"Genome Med"},{"key":"10.1016\/j.jid.2023.01.021_bib26","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1093\/bioinformatics\/btr260","article-title":"Molecular signatures database (MSigDB) 3.0","volume":"27","author":"Liberzon","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2023.01.021_bib27","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1159\/000370226","article-title":"The impact of atopic dermatitis on quality of life","volume":"66","author":"Lifschitz","year":"2015","journal-title":"Ann Nutr Metab"},{"key":"10.1016\/j.jid.2023.01.021_bib28","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000500402","article-title":"Genetics of atopic dermatitis: from DNA sequence to clinical relevance","volume":"235","author":"L\u00f8set","year":"2019","journal-title":"Dermatology"},{"key":"10.1016\/j.jid.2023.01.021_bib29","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1093\/bioinformatics\/btv402","article-title":"LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants","volume":"31","author":"Machiela","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2023.01.021_bib30","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/ng.3643","article-title":"A\u00a0reference panel of 64,976 haplotypes for genotype imputation","volume":"48","author":"McCarthy","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib31","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1096\/fj.201600615R","article-title":"Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis","volume":"30","author":"Mediero","year":"2016","journal-title":"FASEB J"},{"key":"10.1016\/j.jid.2023.01.021_bib32","doi-asserted-by":"crossref","first-page":"6460","DOI":"10.4049\/jimmunol.177.9.6460","article-title":"IL-12 contributes to allergen-induced airway inflammation in experimental asthma","volume":"177","author":"Meyts","year":"2006","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib33","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF02915098","article-title":"Glutamate- and aspartate-like immunoreactivities in human normal and inflamed skin","volume":"64","author":"Nordlind","year":"1993","journal-title":"Virchows Arch B Cell Pathol Incl Mol Pathol"},{"key":"10.1016\/j.jid.2023.01.021_bib34","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jdcr.2017.11.026","article-title":"Concurrence of psoriasis vulgaris and atopic eczema in a single patient exhibiting different expression patterns of psoriatic autoantigens in the lesional skin","volume":"4","author":"Ono","year":"2018","journal-title":"JAAD Case Rep"},{"key":"10.1016\/j.jid.2023.01.021_bib35","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1038\/ng.3424","article-title":"Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis","volume":"47","author":"Paternoster","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2023.01.021_bib36","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1093\/bioinformatics\/btq419","article-title":"LocusZoom: regional visualization of genome-wide association scan results","volume":"26","author":"Pruim","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2023.01.021_bib37","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1111\/ced.13901","article-title":"Psoriasis induced by dupilumab therapy","volume":"44","author":"Safa","year":"2019","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib38","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2023.01.021_bib39","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.4049\/jimmunol.1000435","article-title":"Netrin-1 regulates Th1\/Th2\/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia\u2013reperfusion injury","volume":"185","author":"Tadagavadi","year":"2010","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jid.2023.01.021_bib40","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.jid.2018.12.018","article-title":"Atopic dermatitis is an IL-13\u2013dominant disease with greater molecular heterogeneity compared to psoriasis","volume":"139","author":"Tsoi","year":"2019","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib41","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/s43586-021-00056-9","article-title":"Genome-wide association studies","volume":"1","author":"Uffelmann","year":"2021","journal-title":"Nat Rev Methods Primers"},{"key":"10.1016\/j.jid.2023.01.021_bib42","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jdcr.2020.01.012","article-title":"Dupilumab-induced phenotype switching from atopic dermatitis to psoriasis","volume":"6","author":"Varma","year":"2020","journal-title":"JAAD Case Rep"},{"key":"10.1016\/j.jid.2023.01.021_bib43","doi-asserted-by":"crossref","first-page":"D930","DOI":"10.1093\/nar\/gkr917","article-title":"HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants","volume":"40","author":"Ward","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2023.01.021_bib44","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1365-2133.1994.tb08532.x","article-title":"The U.K. Working Party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation","volume":"131","author":"Williams","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2023.01.021_bib24","unstructured":"King's College London. Biomarkers and stratification to optimise outcomes in psoriasis (BSTOP) study, https:\/\/www.kcl.ac.uk\/lsm\/research\/divisions\/gmm\/departments\/dermatology\/Research\/stru\/groups\/bstop; 2023 (accessed 13 March 2022)."}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X23000775?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X23000775?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:09:24Z","timestamp":1777417764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X23000775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":44,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0022202X23000775"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2023.01.021","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Atopic Polygenic Risk Score Is Associated with Paradoxical Eczema Developing in Patients with Psoriasis Treated with Biologics","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2023.01.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}