{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:25:07Z","timestamp":1792855507520,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004895","name":"European Social Fund Plus","doi-asserted-by":"publisher","award":["PI22\/01847"],"award-info":[{"award-number":["PI22\/01847"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008271","name":"Leo Pharma Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008271","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Celgene Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003185","name":"National Psoriasis Foundation","doi-asserted-by":"publisher","award":["IPT17\/0019"],"award-info":[{"award-number":["IPT17\/0019"]}],"id":[{"id":"10.13039\/100003185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003185","name":"National Psoriasis Foundation","doi-asserted-by":"publisher","award":["IPT17\/0019\\u2014ISCIII-SGEFI\/ERDF"],"award-info":[{"award-number":["IPT17\/0019\\u2014ISCIII-SGEFI\/ERDF"]}],"id":[{"id":"10.13039\/100003185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI21\/00384"],"award-info":[{"award-number":["PI21\/00384"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI22\/01847"],"award-info":[{"award-number":["PI22\/01847"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022606","name":"Almirall SA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000196","name":"Canada Foundation for Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011698","name":"Junta de Comunidades de Castilla-La Mancha","doi-asserted-by":"publisher","award":["SBPLY\/19\/180501\/000226"],"award-info":[{"award-number":["SBPLY\/19\/180501\/000226"]}],"id":[{"id":"10.13039\/501100011698","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011698","name":"Junta de Comunidades de Castilla-La Mancha","doi-asserted-by":"publisher","award":["SBPLY\/21\/180501\/000078"],"award-info":[{"award-number":["SBPLY\/21\/180501\/000078"]}],"id":[{"id":"10.13039\/501100011698","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jid.2023.10.031","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T22:38:59Z","timestamp":1701211139000},"page":"1075-1087.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Association of the Complement System with Subclinical Atherosclerosis in Psoriasis: Findings from an Observational Cohort Study"],"prefix":"10.1016","volume":"144","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3928-1554","authenticated-orcid":false,"given":"Laura","family":"Mourino-Alvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9205-0956","authenticated-orcid":false,"given":"In\u00e9s","family":"Perales-Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0348-5421","authenticated-orcid":false,"given":"Emilio","family":"Berna-Rico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5587-1204","authenticated-orcid":false,"given":"Carlota","family":"Abbad-Jaime de Aragon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5911-9589","authenticated-orcid":false,"given":"Nerea","family":"Corbacho-Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2399-2773","authenticated-orcid":false,"given":"Tamara","family":"Sastre-Oliva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7454-720X","authenticated-orcid":false,"given":"Cristina","family":"Juarez-Alia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6780-0390","authenticated-orcid":false,"given":"Asunci\u00f3n","family":"Ballester-Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6742-1019","authenticated-orcid":false,"given":"Maria","family":"Castellanos-Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1187-1341","authenticated-orcid":false,"given":"Mar","family":"Llamas-Velasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7334-0044","authenticated-orcid":false,"given":"Pedro","family":"Jaen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4227-7062","authenticated-orcid":false,"given":"Jorge","family":"Solis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4237-2166","authenticated-orcid":false,"given":"Leticia","family":"Fernandez-Friera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4939-5130","authenticated-orcid":false,"given":"Neha N.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3480-2661","authenticated-orcid":false,"given":"Joel M.","family":"Gelfand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4290-4721","authenticated-orcid":false,"given":"Maria G.","family":"Barderas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8060-4784","authenticated-orcid":false,"given":"Alvaro","family":"Gonzalez-Cantero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2023.10.031_bib1","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1365-2133.2010.09941.x","article-title":"Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K","volume":"163","author":"Abuabara","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib2","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1160\/TH05-06-0384","article-title":"Complement C3 and C-reactive protein levels in patients with stable coronary artery disease","volume":"94","author":"Ajjan","year":"2005","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jid.2023.10.031_bib3","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.biopha.2018.07.110","article-title":"The pleiotropic role of interleukin-17 in atherosclerosis","volume":"106","author":"Allam","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jid.2023.10.031_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1471-2261-9-51","article-title":"The impact of renal insufficiency and anaemia on survival in patients with cardiovascular disease: a cohort study","volume":"9","author":"Anderson","year":"2009","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.jid.2023.10.031_bib5","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/j.1600-0625.2011.01308.x","article-title":"A\u00a0tale of two plaques: convergent mechanisms of T-cell-mediated inflammation in psoriasis and atherosclerosis","volume":"20","author":"Armstrong","year":"2011","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib6","article-title":"Psoriasis and major adverse cardiovascular events: a systematic review and meta-analysis of observational studies","volume":"2","author":"Armstrong","year":"2013","journal-title":"J\u00a0Am Heart Assoc"},{"key":"10.1016\/j.jid.2023.10.031_bib7","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/1523-1747.ep12513524","article-title":"A-431 cells and human keratinocytes synthesize and secrete the third component of complement","volume":"95","author":"Basset-S\u00e9guin","year":"1990","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib8","doi-asserted-by":"crossref","first-page":"416","DOI":"10.2353\/ajpath.2007.060406","article-title":"Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice","volume":"170","author":"Bhatia","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jid.2023.10.031_bib9","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3389\/fimmu.2018.00579","article-title":"Systemic inflammation and cardiovascular comorbidity in psoriasis patients: causes and consequences","volume":"9","author":"Boehncke","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib10","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000104422","article-title":"Topo-proteomic in situ analysis of psoriatic plaque under efalizumab treatment","volume":"20","author":"Bonnekoh","year":"2007","journal-title":"Skin Pharmacol Physiol"},{"key":"10.1016\/j.jid.2023.10.031_bib11","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.3389\/fimmu.2018.01668","article-title":"Psoriasis, cardiovascular events, and biologics: lights and shadows","volume":"9","author":"Caiazzo","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib12","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.amjcard.2007.02.075","article-title":"Usefulness of the serum complement component C4 as a predictor of stroke in patients with known or suspected coronary artery disease referred for coronary angiography","volume":"100","author":"Cavusoglu","year":"2007","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib13","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.2147\/JIR.S380285","article-title":"DPP4 as a potential candidate in cardiovascular disease","volume":"15","author":"Chen","year":"2022","journal-title":"J\u00a0Inflamm Res"},{"key":"10.1016\/j.jid.2023.10.031_bib14","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1161\/01.CIR.0000144309.87183.FB","article-title":"Insulin-like growth factor-1 as a vascular protective factor","volume":"110","author":"Conti","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jid.2023.10.031_bib15","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/01.hjr.0000244582.30421.b2","article-title":"Complement C3 and C4 in plasma and incidence of myocardial infarction and stroke: a population-based cohort study","volume":"14","author":"Engstr\u00f6m","year":"2007","journal-title":"Eur J Cardiovasc Prev Rehabil"},{"key":"10.1016\/j.jid.2023.10.031_bib16","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1161\/CIRCULATIONAHA.114.014310","article-title":"Prevalence, vascular distribution, and multiterritorial extent of subclinical atherosclerosis in a middle-aged cohort: the PESA (Progression of Early Subclinical Atherosclerosis) Study","volume":"131","author":"Fern\u00e1ndez-Friera","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.jid.2023.10.031_bib17","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1001\/jama.296.14.1735","article-title":"Risk of\u00a0myocardial infarction in patients with psoriasis","volume":"296","author":"Gelfand","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jid.2023.10.031_bib18","doi-asserted-by":"crossref","first-page":"639","DOI":"10.3389\/fimmu.2018.00639","article-title":"Complement activation in inflammatory skin diseases","volume":"9","author":"Giang","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib19","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrneph.2017.51","article-title":"The immunology of atherosclerosis","volume":"13","author":"Gister\u00e5","year":"2017","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.jid.2023.10.031_bib20","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.jaad.2018.07.007","article-title":"Femoral artery ultrasound for improving the detection of atherosclerosis in psoriasis","volume":"80","author":"Gonz\u00e1lez-Cantero","year":"2019","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib21","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/eurjpc\/zwaa033","article-title":"Underperformance of clinical risk scores in identifying imaging-based high cardiovascular risk in psoriasis: results from two observational cohorts","volume":"29","author":"Gonzalez-Cantero","year":"2022","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib22","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6639199","article-title":"Reactive oxygen species and their involvement in red blood cell damage in chronic kidney disease","volume":"2021","author":"Gwozdzinski","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.jid.2023.10.031_bib23","doi-asserted-by":"crossref","first-page":"e3385","DOI":"10.1002\/dmrr.3385","article-title":"Effect of dipeptidyl peptidase-4 inhibitors on complement activation","volume":"37","author":"Hoffmann-Petersen","year":"2021","journal-title":"Diabetes Metab Res Rev"},{"key":"10.1016\/j.jid.2023.10.031_bib24","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.atherosclerosis.2022.03.014","article-title":"The multifaceted impact of complement on atherosclerosis","volume":"351","author":"Kiss","year":"2022","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jid.2023.10.031_bib25","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2147\/CCID.S216422","article-title":"Effect of narrowband ultraviolet B therapy on serum levels of CD26\/dipeptidyl-peptidase IV and truncated forms of substance P in psoriasis patients with pruritus","volume":"12","author":"Kongthong","year":"2019","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib26","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1089\/ars.2016.6954","article-title":"Red blood cell function and dysfunction: redox regulation, nitric oxide metabolism, anemia","volume":"26","author":"Kuhn","year":"2017","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.jid.2023.10.031_bib27","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/S0002-9149(02)02498-0","article-title":"Evidence for complement activation in ruptured coronary plaques in acute myocardial infarction","volume":"90","author":"Laine","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib28","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.molimm.2009.10.035","article-title":"The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice","volume":"47","author":"Lewis","year":"2010","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib29","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.imlet.2013.09.025","article-title":"Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-\/-) mice","volume":"156","author":"Li","year":"2013","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jid.2023.10.031_bib30","first-page":"10","article-title":"Complement factor H and related proteins as markers of cardiovascular risk in pediatric chronic kidney disease","author":"Liao","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.jid.2023.10.031_bib31","article-title":"Psoriasis increased the risk of adverse cardiovascular outcomes: a new systematic review and meta-analysis of cohort study","volume":"9","author":"Liu","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.jid.2023.10.031_bib32","article-title":"The effects of IL-17\/IL-17R inhibitors on atherosclerosis in psoriasis and psoriatic arthritis: A protocol for systematic review and meta analysis","volume":"100","author":"Liu","year":"2021","journal-title":"Medicine"},{"key":"10.1016\/j.jid.2023.10.031_bib33","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.594735","article-title":"The IL-23\/IL-17 pathway in inflammatory skin diseases: from bench to bedside","volume":"11","author":"Liu","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/08830185.2018.1539084","article-title":"Psoriasis and cardiovascular disease: the elusive link","volume":"38","author":"Manolis","year":"2019","journal-title":"Int Rev Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib35","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1016\/j.jacc.2020.02.058","article-title":"Complement C5 protein as a marker of subclinical atherosclerosis","volume":"75","author":"Mart\u00ednez-L\u00f3pez","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib36","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1007\/s12325-020-01346-6","article-title":"Psoriasis and cardiovascular risk: a comprehensive review","volume":"37","author":"Masson","year":"2020","journal-title":"Adv Ther"},{"key":"10.1016\/j.jid.2023.10.031_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjmed.2011.03.028","article-title":"Attributable risk estimate of severe psoriasis on major cardiovascular events","volume":"124","author":"Mehta","year":"2011","journal-title":"Am J Med"},{"key":"10.1016\/j.jid.2023.10.031_bib38","first-page":"345","article-title":"Relationship between serum C3 levels and traditional risk factors for myocardial infarction","volume":"53","author":"Muscari","year":"1998","journal-title":"Acta Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib39","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1385\/IR:30:1:073","article-title":"The role of complement activation in atherosclerosis","volume":"30","author":"Niculescu","year":"2004","journal-title":"Immunol Res"},{"key":"10.1016\/j.jid.2023.10.031_bib40","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/j.molimm.2011.04.004","article-title":"Complement factor I in health and disease","volume":"48","author":"Nilsson","year":"2011","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib41","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.semnephrol.2013.08.001","article-title":"Overview of complement activation and regulation","volume":"33","author":"Noris","year":"2013","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.jid.2023.10.031_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.103874","article-title":"Unbiased plasma proteomics discovery of biomarkers for improved detection of subclinical atherosclerosis","volume":"76","author":"N\u00fa\u00f1ez","year":"2022","journal-title":"EBiomedicine"},{"key":"10.1016\/j.jid.2023.10.031_bib43","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/annrheumdis-2014-205675","article-title":"Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study","volume":"74","author":"Ogdie","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jid.2023.10.031_bib44","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/exd.14228","article-title":"The role of dipeptidyl peptidase-4 in cutaneous disease","volume":"30","author":"Patel","year":"2021","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib45","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00403-016-1712-1","article-title":"Psoriasis and cardiovascular events: updating the evidence","volume":"309","author":"Raaby","year":"2017","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.jid.2023.10.031_bib46","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/jcp.1041510219","article-title":"Characterization of specific proteases associated with the surface of human skin fibroblasts, and their modulation in pathology","volume":"151","author":"Raynaud","year":"1992","journal-title":"J\u00a0Cell Physiol"},{"key":"10.1016\/j.jid.2023.10.031_bib47","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/ni.1923","article-title":"Complement: a key system\u00a0for immune surveillance and homeostasis","volume":"11","author":"Ricklin","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib48","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s12975-018-0658-3","article-title":"Complement Complex C5b-9 levels are associated with the clinical outcomes of acute ischemic stroke and carotid plaque stability","volume":"10","author":"Si","year":"2019","journal-title":"Transl Stroke Res"},{"key":"10.1016\/j.jid.2023.10.031_bib49","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.molimm.2013.06.001","article-title":"Complement factor H related proteins (CFHRs)","volume":"56","author":"Skerka","year":"2013","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib50","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1538-7836.2010.04172.x","article-title":"Complement in atherosclerosis: friend or foe?","volume":"9","author":"Speidl","year":"2011","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.jid.2023.10.031_bib51","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.atherosclerosis.2004.07.022","article-title":"Association of high serum concentration of the third component of complement (C3) with pre-existing severe coronary artery disease and new vascular events in women","volume":"177","author":"Sz\u00e9plaki","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jid.2023.10.031_bib52","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1159\/000247461","article-title":"Generation of terminal complement complexes in psoriatic lesional skin","volume":"185","author":"Takematsu","year":"1992","journal-title":"Dermatol (Basel Switzerland)"},{"key":"10.1016\/j.jid.2023.10.031_bib53","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/j.jacc.2017.07.750","article-title":"Unraveling vascular inflammation: from immunology to imaging","volume":"70","author":"Teague","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jid.2023.10.031_bib54","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1016\/j.molimm.2006.12.014","article-title":"Expression of terminal complement components by human keratinocytes","volume":"44","author":"Tim\u00e1r","year":"2007","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib55","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.molimm.2005.02.009","article-title":"Human keratinocytes produce the complement inhibitor factor H: synthesis is regulated by interferon-gamma","volume":"43","author":"Tim\u00e1r","year":"2006","journal-title":"Mol Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib56","first-page":"11","article-title":"The impact of treatment with IL-17\/IL-23 inhibitors on subclinical atherosclerosis in patients with plaque psoriasis and\/or psoriatic arthritis: a systematic review","author":"Tsiogka","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.jid.2023.10.031_bib57","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/1523-1747.ep12371679","article-title":"The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response","volume":"101","author":"Uyemura","year":"1993","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib58","article-title":"Interleukin-17 links inflammatory cross-talks between comorbid psoriasis and atherosclerosis","volume":"13","author":"Wang","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2023.10.031_bib59","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1161\/ATVBAHA.120.314150","article-title":"Protective role of C3aR (C3a anaphylatoxin receptor) against atherosclerosis in atherosclerosis-prone mice","volume":"40","author":"Wei","year":"2020","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jid.2023.10.031_bib60","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/1523-1747.ep12499812","article-title":"Human keratinocytes and A-431 cells synthesize and secrete factor B, the major zymogen protease of the alternative complement pathway","volume":"98","author":"Yancey","year":"1992","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib61","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1161\/hq0701.092160","article-title":"Complement components, but not complement inhibitors, are upregulated in atherosclerotic plaques","volume":"21","author":"Yasojima","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jid.2023.10.031_bib62","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1111\/j.1365-4632.2010.04799.x","article-title":"CD26\/dipeptidyl-peptidase IV and adenosine deaminase serum levels in psoriatic patients treated with cyclosporine, etanercept, and psoralen plus ultraviolet A phototherapy","volume":"50","author":"Y\u0131ld\u0131r\u0131m","year":"2011","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jid.2023.10.031_bib63","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nmeth.1322","article-title":"Universal sample preparation method for proteome analysis","volume":"6","author":"Wi\u015bniewski","year":"2009","journal-title":"Nat Methods"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X23031123?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X23031123?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:09:35Z","timestamp":1777417775000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X23031123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":63,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0022202X23031123"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2023.10.031","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of the Complement System with Subclinical Atherosclerosis in Psoriasis: Findings from an Observational Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2023.10.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier, Inc. on behalf of the Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}]}}