{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:00:05Z","timestamp":1790820005957,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81130031"],"award-info":[{"award-number":["81130031"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jid.2025.03.019","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T14:37:25Z","timestamp":1743691045000},"page":"2606-2609.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcriptome and Chromatin Landscape Changes Associated with Pathogenesis of Psoriasis in Memory T Helper and Memory Regulatory T Cells"],"prefix":"10.1016","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1327-5404","authenticated-orcid":false,"given":"Mengyun","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengcheng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyuan","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiran","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuejun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5156-092X","authenticated-orcid":false,"given":"Zheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5331-0323","authenticated-orcid":false,"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2025.03.019_bib1","article-title":"High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci","volume":"74","author":"Kim","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jid.2025.03.019_bib2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/s41588-018-0278-6","article-title":"High-resolution genetic mapping of putative causal interactions between regions of open chromatin","volume":"51","author":"Kumasaka","year":"2019","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2025.03.019_bib3","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/hmg\/ddy395","article-title":"Genetic influences on susceptibility to rheumatoid arthritis in African-Americans","volume":"28","author":"Laufer","year":"2019","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jid.2025.03.019_bib4","article-title":"From PsO to PsA: the role of TRM and Tregs in psoriatic disease, a systematic review of the literature","volume":"11","author":"Lob\u00e3o","year":"2024","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.jid.2025.03.019_bib5","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature12873","article-title":"Genetics of rheumatoid arthritis contributes to biology and drug discovery","volume":"506","author":"Okada","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jid.2025.03.019_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2024.03.013","article-title":"From GWASs toward mechanistic understanding with case studies in Dermatogenetics","volume":"144","author":"Shen","year":"2024","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jid.2025.03.019_bib7","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1002\/1873-3468.13456","article-title":"HIC2, a new transcription activator of SIRT1","volume":"593","author":"Song","year":"2019","journal-title":"FEBS Lett"},{"key":"10.1016\/j.jid.2025.03.019_bib8","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s00018-022-04349-4","article-title":"BRD2 interconnects with BRD3 to facilitate Pol II transcription initiation and elongation to prime promoters for cell differentiation","volume":"79","author":"Wang","year":"2022","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jid.2025.03.019_bib9","doi-asserted-by":"crossref","first-page":"700","DOI":"10.7150\/thno.47800","article-title":"PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail1","volume":"11","author":"Wu","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.jid.2025.03.019_bib10","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s11684-021-0872-3","article-title":"Characterization of chromatin accessibility in psoriasis","volume":"16","author":"Zhang","year":"2022","journal-title":"Front Med"},{"key":"10.1016\/j.jid.2025.03.019_bib11","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2025.03.019_bib12","doi-asserted-by":"crossref","first-page":"D165","DOI":"10.1093\/nar\/gkab1113","article-title":"JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles","volume":"50","author":"Castro-Mondragon","year":"2022","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2025.03.019_bib13","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1093\/bioinformatics\/btv470","article-title":"motifbreakR: an R\/Bioconductor package for predicting variant effects at transcription factor binding sites","volume":"31","author":"Coetzee","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2025.03.019_bib14","doi-asserted-by":"crossref","first-page":"D794","DOI":"10.1093\/nar\/gkx1081","article-title":"The Encyclopedia of DNA elements (ENCODE): data portal update","volume":"46","author":"Davis","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2025.03.019_bib15","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ajhg.2015.11.021","article-title":"An efficient multiple-testing adjustment for eQTL studies that accounts for linkage disequilibrium between variants","volume":"98","author":"Davis","year":"2016","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jid.2025.03.019_bib16","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jid.2025.03.019_bib17","doi-asserted-by":"crossref","first-page":"2:2.14.1","DOI":"10.1002\/0471250953.bi0214s34","article-title":"Using MACS to identify peaks from ChIP-Seq data","volume":"34","author":"Feng","year":"2011","journal-title":"Curr Protoc Bioinformatics"},{"key":"10.1016\/j.jid.2025.03.019_bib18","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/biostatistics\/kxr054","article-title":"Removing technical variability in RNA-seq data using conditional quantile normalization","volume":"13","author":"Hansen","year":"2012","journal-title":"Biostatistics"},{"key":"10.1016\/j.jid.2025.03.019_bib19","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.molcel.2010.05.004","article-title":"Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities","volume":"38","author":"Heinz","year":"2010","journal-title":"Mol Cell"},{"key":"10.1016\/j.jid.2025.03.019_bib20","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/ng.548","article-title":"Variance component model to account for sample structure in genome-wide association studies","volume":"42","author":"Kang","year":"2010","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2025.03.019_bib21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat Methods"},{"key":"10.1016\/j.jid.2025.03.019_bib22","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/1471-2105-12-323","article-title":"RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome","volume":"12","author":"Li","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jid.2025.03.019_bib23","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jid.2025.03.019_bib24","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1038\/nbt.2931","article-title":"Normalization of RNA-seq data using factor analysis of control genes or samples","volume":"32","author":"Risso","year":"2014","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jid.2025.03.019_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nature14248","article-title":"Integrative analysis of 111 reference human epigenomes","volume":"518","author":"Meuleman","year":"2015","journal-title":"Nature"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X25003823?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X25003823?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:21:15Z","timestamp":1790817675000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X25003823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0022202X25003823"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2025.03.019","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptome and Chromatin Landscape Changes Associated with Pathogenesis of Psoriasis in Memory T Helper and Memory Regulatory T Cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2025.03.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Society for Investigative Dermatology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}