{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:00:14Z","timestamp":1780725614250,"version":"3.54.1"},"reference-count":9,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jid.2026.01.001","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T20:33:22Z","timestamp":1771619602000},"page":"876-878","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The plot thickens in pemphigus: New therapeutic targets from state-of-the-art ex vivo assays"],"prefix":"10.1016","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2971-0199","authenticated-orcid":false,"given":"Dedee F.","family":"Murrell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yamagami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2026.01.001_bib1","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.25122\/jml-2023-0226","article-title":"Cut-off values for IL-21 and IL-23 as biochemical markers for pemphigus vulgaris","volume":"16","author":"Al-Hasnawi","year":"2023","journal-title":"J Med Life"},{"key":"10.1016\/j.jid.2026.01.001_bib3","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1038\/nm1292","article-title":"Direct access to CD4+ T cells specific for defined antigens according to CD154 expression","volume":"11","author":"Frentsch","year":"2005","journal-title":"Nat Med"},{"key":"10.1016\/j.jid.2026.01.001_bib4","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/cts.12715","article-title":"A double-blind, Phase I, single ascending dose study to assess the safety, pharmacokinetics, and pharmacodynamics of BOS161721 in healthy subjects","volume":"13","author":"Hussaini","year":"2020","journal-title":"Clin Transl Sci"},{"key":"10.1016\/j.jid.2026.01.001_bib5","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00105-019-4414-8","article-title":"M\u00f6gliche Wirkung einer Interleukin-17-Blockade beim Pemphigus foliaceus und neutrophilen Erkrankungen [Possible effect of interleukin-17 blockade in pemphigus foliaceus and neutrophilic diseases]","volume":"70","author":"Kohlmann","year":"2019","journal-title":"Hautarzt"},{"key":"10.1016\/j.jid.2026.01.001_bib6","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.jid.2025.08.039","article-title":"Deep analysis of desmoglein-3\u2013reactive CD4+ T cells in pemphigus vulgaris reveals a type 17\/type 2 T-cell signature","volume":"146","author":"Marschall","year":"2026","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jid.2026.01.001_bib7","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/imcb.12636","article-title":"T-cell activation-induced marker assays in health and disease","volume":"101","author":"Poloni","year":"2023","journal-title":"Immunol Cell Biol"},{"key":"10.1016\/j.jid.2026.01.001_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1500231","article-title":"Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls","volume":"15","author":"Schwartz","year":"2024","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2026.01.001_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.intimp.2016.02.020","article-title":"Interleukin 21 as a new possible player in pemphigus: is it a suitable target?","volume":"34","author":"Tavakolpour","year":"2016","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jid.2026.01.001_bib10","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1016\/j.jid.2021.01.030","article-title":"The pathogenic role of CD4+ tissue-resident memory T cells bearing T follicular helper-like phenotype in pemphigus lesions","volume":"141","author":"Zou","year":"2021","journal-title":"J Invest Dermatol"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X26000175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X26000175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:03:45Z","timestamp":1780722225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X26000175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S0022202X26000175"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2026.01.001","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The plot thickens in pemphigus: New therapeutic targets from state-of-the-art ex vivo assays","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2026.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2025.08.039","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Society for Investigative Dermatology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}