{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:45:06Z","timestamp":1792010706019,"version":"4.4.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008456","name":"A. Alfred Taubman Medical Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008456","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30-A075043"],"award-info":[{"award-number":["P30-A075043"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01-AI179251"],"award-info":[{"award-number":["P01-AI179251"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jidonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jid.2026.08.011","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:01:37Z","timestamp":1789023697000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Divergent cytotoxic and immunomodulatory immune programs distinguish morbilliform drug eruption from SDRIFE"],"prefix":"10.1016","author":[{"given":"Laura B.","family":"Chopp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianying","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael","family":"Bogle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kirma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Michelle","family":"Kahlenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lam C.","family":"Tsoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May P.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann E.","family":"Gudjonsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jid.2026.08.011_bib1","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1038\/nm.3962","article-title":"Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma","volume":"21","author":"Adachi","year":"2015","journal-title":"Nat Med"},{"key":"10.1016\/j.jid.2026.08.011_bib2","doi-asserted-by":"crossref","first-page":"7783","DOI":"10.1073\/pnas.1722056115","article-title":"CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function","volume":"115","author":"Bandala-Sanchez","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jid.2026.08.011_bib3","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/ni.2610","article-title":"T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10","volume":"14","author":"Bandala-Sanchez","year":"2013","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib4","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/s41590-019-0479-x","article-title":"Flip the coin: il-7 and IL-7R in health and disease","volume":"20","author":"Barata","year":"2019","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib5","doi-asserted-by":"crossref","first-page":"436","DOI":"10.4049\/jimmunol.178.1.436","article-title":"A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte\/macrophage physiology through a nonapoptotic ERK-dependent pathway","volume":"178","author":"Barrionuevo","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib6","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aaw2938","article-title":"A key role for IL-13 signaling via the type 2 IL-4 receptor in experimental atopic dermatitis","volume":"5","author":"Bitton","year":"2020","journal-title":"Sci Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib7","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/s12967-022-03375-x","article-title":"IL-32 promotes the occurrence of atopic dermatitis by activating the JAK1\/microRNA-155 axis","volume":"20","author":"Chang","year":"2022","journal-title":"J Transl Med"},{"key":"10.1016\/j.jid.2026.08.011_bib8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/DAD.0000000000002455","article-title":"Characterization of T-helper immune phenotype in symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) endorses a delayed-type hypersensitivity reaction","volume":"46","author":"Chaudet","year":"2024","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jid.2026.08.011_bib9","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2105-14-128","article-title":"Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool","volume":"14","author":"Chen","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.jid.2026.08.011_bib10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jaci.2022.10.011","article-title":"From thymus to tissues and tumors: a review of T-cell biology","volume":"151","author":"Chopp","year":"2023","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.drudis.2025.104455","article-title":"Galectins in inflammatory skin diseases: current roles and future directions","volume":"30","author":"Corr\u00eaa","year":"2025","journal-title":"Drug Discov Today"},{"key":"10.1016\/j.jid.2026.08.011_bib12","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1111\/bcp.15490","article-title":"Drugs and the skin: a concise review of cutaneous adverse drug reactions","volume":"90","author":"Del Pozzo-Maga\u00f1a","year":"2024","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jid.2026.08.011_bib13","doi-asserted-by":"crossref","DOI":"10.1172\/JCI182040","article-title":"IL-32-producing CD8+ memory T cells define immunoregulatory niches in human cutaneous leishmaniasis","volume":"135","author":"Dey","year":"2025","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jid.2026.08.011_bib14","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1038\/s41596-020-0292-x","article-title":"CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes","volume":"15","author":"Efremova","year":"2020","journal-title":"Nat Protoc"},{"key":"10.1016\/j.jid.2026.08.011_bib15","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.jaad.2008.09.015","article-title":"Cutaneous drug eruptions: a 5-year experience","volume":"59","author":"Gerson","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jid.2026.08.011_bib16","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.4049\/jimmunol.174.3.1723","article-title":"CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells","volume":"174","author":"G\u00fcnther","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib17","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1089\/jir.2010.0076","article-title":"Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity","volume":"31","author":"Haller","year":"2011","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.jid.2026.08.011_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1163924","article-title":"Comprehensive exploration of M2 macrophages and its related genes for predicting clinical outcomes and drug sensitivity in lung squamous cell carcinoma","volume":"2022","author":"Han","year":"2022","journal-title":"J Oncol"},{"key":"10.1016\/j.jid.2026.08.011_bib19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41587-023-01767-y","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","volume":"42","author":"Hao","year":"2024","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jid.2026.08.011_bib20","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.0105-1873.2004.00445.x","article-title":"Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome?","volume":"51","author":"H\u00e4usermann","year":"2004","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jid.2026.08.011_bib21","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1084\/jem.20130240","article-title":"Identification of human CCR8 as a CCL18 receptor","volume":"210","author":"Islam","year":"2013","journal-title":"J Exp Med"},{"key":"10.1016\/j.jid.2026.08.011_bib22","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1002\/jcp.24643","article-title":"CCL27 is downregulated by interferon gamma via epidermal growth factor receptor in normal human epidermal keratinocytes","volume":"229","author":"Karakawa","year":"2014","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.jid.2026.08.011_bib23","first-page":"322","article-title":"Symmetrical drug-related intertriginous and flexural exanthema (baboon syndrome) associated with infliximab: a case-based review","volume":"1","author":"Keshavamurthy","year":"2022","journal-title":"ARP Rheumatol"},{"key":"10.1016\/j.jid.2026.08.011_bib24","doi-asserted-by":"crossref","first-page":"W90","DOI":"10.1093\/nar\/gkw377","article-title":"Enrichr: a comprehensive gene set enrichment analysis web server 2016 update","volume":"44","author":"Kuleshov","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jid.2026.08.011_bib25","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3389\/fmed.2018.00271","article-title":"The role of CXCR3 and its chemokine ligands in skin disease and cancer","volume":"5","author":"Kuo","year":"2018","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.jid.2026.08.011_bib26","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jaci.2019.12.905","article-title":"IL-32\u03b3 suppressed atopic dermatitis through inhibition of miR-205 expression via inactivation of nuclear factor-kappa B","volume":"146","author":"Lee","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib27","article-title":"CCL13 and human diseases","volume":"14","author":"Li","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib28","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"key":"10.1016\/j.jid.2026.08.011_bib29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cels.2019.03.003","article-title":"DoubletFinder: doublet detection in single-cell RNA sequencing data using artificial nearest neighbors","volume":"8","author":"McGinnis","year":"2019","journal-title":"Cell Syst"},{"key":"10.1016\/j.jid.2026.08.011_bib30","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.jaci.2010.01.016","article-title":"IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis","volume":"125","author":"Meyer","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib31","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1111\/all.15781","article-title":"Spatial transcriptomics combined with single-cell RNA-sequencing unravels the complex inflammatory cell network in atopic dermatitis","volume":"78","author":"Mitamura","year":"2023","journal-title":"Allergy"},{"key":"10.1016\/j.jid.2026.08.011_bib32","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/bcp.16390","article-title":"Infliximab-induced symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) in a patient with ulcerative colitis","volume":"91","author":"Mokos","year":"2025","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.jid.2026.08.011_bib33","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1002\/eji.200838295","article-title":"Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function","volume":"38","author":"Motran","year":"2008","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib34","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/DAD.0000000000001722","article-title":"Histopathological spectrum and immunophenotypic characterization of symmetrical drug-related intertriginous and flexural exanthema","volume":"43","author":"Muresan","year":"2021","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jid.2026.08.011_bib35","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1097\/DAD.0b013e31820a285d","article-title":"Histopathologic features of exanthematous drug eruptions of the macular and papular type","volume":"33","author":"Naim","year":"2011","journal-title":"Am J Dermatopathol"},{"key":"10.1016\/j.jid.2026.08.011_bib36","article-title":"The hidden sentinel of the skin: an overview on the role of interleukin-13 in atopic dermatitis","volume":"10","author":"Napolitano","year":"2023","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.jid.2026.08.011_bib37","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/cod.13084","article-title":"Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) associated with pristinamycin, secnidazole, and nefopam, with a review of the literature","volume":"79","author":"Nespoulous","year":"2018","journal-title":"Contact Dermat"},{"key":"10.1016\/j.jid.2026.08.011_bib38","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1038\/s41590-020-0758-6","article-title":"The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation [published correction appears in Nat Immunol 2024;25:716]","volume":"21","author":"Ng","year":"2020","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib39","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1038\/s41590-022-01339-3","article-title":"IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation","volume":"23","author":"Ni","year":"2022","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib40","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/s41592-021-01358-2","article-title":"Squidpy: a scalable framework for spatial omics analysis","volume":"19","author":"Palla","year":"2022","journal-title":"Nat Methods"},{"key":"10.1016\/j.jid.2026.08.011_bib41","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1111\/cup.14090","article-title":"Symmetric drug-related intertriginous and flexural exanthema: clinicopathologic study of 19 cases and review of literature","volume":"48","author":"Schuler","year":"2021","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.jid.2026.08.011_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aao4650","article-title":"Humidity-regulated CLCA2 protects the epidermis from hyperosmotic stress","volume":"10","author":"Seltmann","year":"2018","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.jid.2026.08.011_bib43","doi-asserted-by":"crossref","DOI":"10.1172\/JCI178253","article-title":"Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets","volume":"134","author":"Shah","year":"2024","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jid.2026.08.011_bib44","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/s41588-024-01664-3","article-title":"BANKSY unifies cell typing and tissue domain segmentation for scalable spatial omics data analysis","volume":"56","author":"Singhal","year":"2024","journal-title":"Nat Genet"},{"key":"10.1016\/j.jid.2026.08.011_bib45","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/cod.14594","article-title":"Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) after administration of corticosteroids: case series and review of literature","volume":"91","author":"Steininger","year":"2024","journal-title":"Contact Dermat"},{"key":"10.1016\/j.jid.2026.08.011_bib46","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/ACI.0b013e3283489d5f","article-title":"Symmetrical drug-related intertriginous and flexural exanthema","volume":"11","author":"Tan","year":"2011","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib47","doi-asserted-by":"crossref","first-page":"22662","DOI":"10.1074\/jbc.M115.644799","article-title":"Galectin-1 regulates tissue exit of specific dendritic cell populations","volume":"290","author":"Thiemann","year":"2015","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jid.2026.08.011_bib48","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/cmi.2013.35","article-title":"Immune regulation by CD52-expressing CD4 T cells","volume":"10","author":"Toh","year":"2013","journal-title":"Cell Mol Immunol"},{"key":"10.1016\/j.jid.2026.08.011_bib49","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1007\/s00018-005-5242-9","article-title":"Identification of factor XIII-A as a marker of alternative macrophage activation","volume":"62","author":"T\u00f6r\u00f6csik","year":"2005","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jid.2026.08.011_bib50","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1038\/jid.2008.447","article-title":"The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions","volume":"129","author":"Velasco","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jid.2026.08.011_bib51","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.iac.2022.10.005","article-title":"Drug hypersensitivity reactions","volume":"43","author":"Wilkerson","year":"2023","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.1016\/j.jid.2026.08.011_bib52","doi-asserted-by":"crossref","first-page":"e90","DOI":"10.1002\/cpz1.90","article-title":"Gene set knowledge discovery with Enrichr","volume":"1","author":"Xie","year":"2021","journal-title":"Curr Protoc"},{"key":"10.1016\/j.jid.2026.08.011_bib53","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70091","article-title":"Single-cell dissection reveals immunosuppressive F13A1+ macrophage as a hallmark for multiple primary lung cancers","volume":"14","author":"Yang","year":"2024","journal-title":"Clin Transl Med"},{"key":"10.1016\/j.jid.2026.08.011_bib54","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giaa151","article-title":"SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data","volume":"9","author":"Young","year":"2020","journal-title":"GigaScience"},{"key":"10.1016\/j.jid.2026.08.011_bib55","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1016\/j.immuni.2024.11.010","article-title":"Skin immune-mesenchymal interplay within tertiary lymphoid structures promotes autoimmune pathogenesis in hidradenitis suppurativa","volume":"57","author":"Yu","year":"2024","journal-title":"Immunity"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X26027983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X26027983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:55:05Z","timestamp":1792007705000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X26027983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":55,"alternative-id":["S0022202X26027983"],"URL":"https:\/\/doi.org\/10.1016\/j.jid.2026.08.011","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Divergent cytotoxic and immunomodulatory immune programs distinguish morbilliform drug eruption from SDRIFE","name":"articletitle","label":"Article Title"},{"value":"Journal of Investigative Dermatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jid.2026.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Society for Investigative Dermatology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}