{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T18:02:25Z","timestamp":1771264945211,"version":"3.50.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100014421","name":"EA Pharma Co., Ltd.","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014421","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003627","name":"Rural Development Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003627","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Immunological Methods"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.jim.2012.06.001","type":"journal-article","created":{"date-parts":[[2012,6,10]],"date-time":"2012-06-10T07:37:00Z","timestamp":1339313820000},"page":"143-147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Stability of orally administered immunoglobulin in the gastrointestinal tract"],"prefix":"10.1016","volume":"384","author":[{"given":"Jeongmin","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae-Eun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee-Jong","family":"Woo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jim.2012.06.001_bb0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1385\/IR:21:1:1","article-title":"Peroral immunotherapy with yolk antibodies for the prevention and treatment of enteric infections","volume":"21","author":"Carlander","year":"2000","journal-title":"Immunol. Res."},{"key":"10.1016\/j.jim.2012.06.001_bb0010","first-page":"295","article-title":"Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken: a review","volume":"13","author":"Chalghoumi","year":"2009","journal-title":"Biotechnol. Agron. Soc."},{"key":"10.1016\/j.jim.2012.06.001_bb0015","doi-asserted-by":"crossref","first-page":"E148","DOI":"10.1111\/j.1365-2621.2005.tb07088.x","article-title":"Protective effect of microencapsulation consisting of multiple emulsification and heat gelation processes on immunoglobulin in yolk","volume":"70","author":"Cho","year":"2005","journal-title":"J. Food Sci."},{"key":"10.1016\/j.jim.2012.06.001_bb0020","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1186\/cc1819","article-title":"Bovine colostrum in oral treatment of enterogenic endotoxaemia in rats","volume":"6","author":"Dohler","year":"2002","journal-title":"Crit. Care"},{"key":"10.1016\/j.jim.2012.06.001_bb0025","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00216-007-1391-z","article-title":"Analysis of bovine immunoglobulin G in milk, colostrum and dietary supplements: a review","volume":"389","author":"Gapper","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jim.2012.06.001_bb0030","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/infdis\/156.1.158","article-title":"Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants","volume":"156","author":"Hilpert","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jim.2012.06.001_bb0035","doi-asserted-by":"crossref","first-page":"118","DOI":"10.11150\/kansenshogakuzasshi1970.64.118","article-title":"Prevention of human rotavirus infection with chicken egg yolk immunoglobulins containing rotavirus antibody in cat","volume":"64","author":"Hiraga","year":"1990","journal-title":"Kansenshogaku Zasshi"},{"key":"10.1016\/j.jim.2012.06.001_bb0040","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.3168\/jds.S0022-0302(04)73549-3","article-title":"Suppressive effect of functional drinking yogurt containing specific egg yolk immunoglobulin on Helicobacter pylori in humans","volume":"87","author":"Horie","year":"2004","journal-title":"J. Dairy. Sci."},{"issue":"Suppl. 1","key":"10.1016\/j.jim.2012.06.001_bb0045","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1017\/S0007114500002282","article-title":"Milk immunoglobulins and complement factors","volume":"84","author":"Korhonen","year":"2000","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.jim.2012.06.001_bb0090","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0378-1135(93)90188-D","article-title":"Passive protection against bovine rotavirus-induced diarrhea in murine model by specific immunoglobulins from chicken egg yolk","volume":"37","author":"Kuroki","year":"1993","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.jim.2012.06.001_bb0055","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF01310045","article-title":"Passive protection against bovine rotavirus in calves by specific immunoglobulins from chicken egg yolk","volume":"138","author":"Kuroki","year":"1994","journal-title":"Arch. Virol."},{"key":"10.1016\/j.jim.2012.06.001_bb0060","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.3382\/ps.0721807","article-title":"Chicken antibodies: taking advantage of evolution\u2014a review","volume":"72","author":"Larsson","year":"1993","journal-title":"Poult. Sci."},{"key":"10.1016\/j.jim.2012.06.001_bb0065","first-page":"1756","article-title":"Antigenicity of partial fragments of recombinant Pasteurella multocida toxin","volume":"20","author":"Lee","year":"2010","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.jim.2012.06.001_bb0070","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1046\/j.1523-5378.2003.00144.x","article-title":"Prevention and suppression of Helicobacter felis infection in mice using colostral preparation with specific antibodies","volume":"8","author":"Marnila","year":"2003","journal-title":"Helicobacter"},{"key":"10.1016\/j.jim.2012.06.001_bb0075","first-page":"19","article-title":"Randomized, placebo-controlled, clinical trial of hyperimmunized chicken egg yolk immunoglobulin in children with rotavirus diarrhea","volume":"32","author":"Sarker","year":"2001","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.jim.2012.06.001_bb0080","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/mrm.10207","article-title":"Gastrointestinal transit times in mice and humans measured with 27Al and 19F nuclear magnetic resonance","volume":"48","author":"Schwarz","year":"2002","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.jim.2012.06.001_bb0085","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/BF02731112","article-title":"Therapeutic potentials of bovine colostrums","volume":"72","author":"Thapa","year":"2005","journal-title":"Indian J. Pediatr."}],"container-title":["Journal of Immunological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175912001627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175912001627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T15:58:43Z","timestamp":1762185523000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022175912001627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":17,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0022175912001627"],"URL":"https:\/\/doi.org\/10.1016\/j.jim.2012.06.001","relation":{},"ISSN":["0022-1759"],"issn-type":[{"value":"0022-1759","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stability of orally administered immunoglobulin in the gastrointestinal tract","name":"articletitle","label":"Article Title"},{"value":"Journal of Immunological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jim.2012.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}