{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T10:59:24Z","timestamp":1789901964354,"version":"4.0.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AI081541"],"award-info":[{"award-number":["R21AI081541"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["510448"],"award-info":[{"award-number":["510448"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Immunological Methods"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.jim.2012.07.006","type":"journal-article","created":{"date-parts":[[2012,7,24]],"date-time":"2012-07-24T07:21:13Z","timestamp":1343114473000},"page":"51-61","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":61,"title":["Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity"],"prefix":"10.1016","volume":"384","author":[{"given":"M.","family":"Kramski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Schorcht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.P.R.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.F.","family":"Lichtfuss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Jegaskanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"De Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Stratov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.D.","family":"Kelleher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"French","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.J.","family":"Center","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Jaworowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.J.","family":"Kent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jim.2012.07.006_bb0005","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jim.2010.12.016","article-title":"A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples","volume":"366","author":"Ackerman","year":"2011","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jim.2012.07.006_bb0010","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1023\/A:1011087132180","article-title":"Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection","volume":"21","author":"Ahmad","year":"2001","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2796.2008.02045.x","article-title":"NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection","volume":"265","author":"Alter","year":"2009","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0020","first-page":"362","article-title":"A mechanism for neutrophil-mediated lysis of human neuroblastoma cells","volume":"53","author":"Barker","year":"1993","journal-title":"Cancer Res."},{"key":"10.1016\/j.jim.2012.07.006_bb0025","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1086\/338828","article-title":"Antibody-dependent cell-mediated cytotoxicity in cervical lavage fluids of human immunodeficiency virus type 1\u2010infected women","volume":"185","author":"Battle-Miller","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jim.2012.07.006_bb0030","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.4049\/jimmunol.157.5.2168","article-title":"HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression","volume":"157","author":"Baum","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0035","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/COH.0b013e3283457798","article-title":"Natural killer cells in spontaneous control of HIV infection","volume":"6","author":"Berger","year":"2011","journal-title":"Curr. Opin. HIV AIDS"},{"key":"10.1016\/j.jim.2012.07.006_bb0040","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1084\/jem.172.6.1633","article-title":"Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes","volume":"172","author":"Bouharoun-Tayoun","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0045","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1084\/jem.182.2.409","article-title":"Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages","volume":"182","author":"Bouharoun-Tayoun","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0050","doi-asserted-by":"crossref","first-page":"6605","DOI":"10.1016\/j.vaccine.2009.08.016","article-title":"Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens","volume":"27","author":"Center","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2012.07.006_bb0060","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.4049\/jimmunol.182.2.1202","article-title":"Rapid degranulation of NK cells following activation by HIV-specific antibodies","volume":"182","author":"Chung","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0055","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/QAI.0b013e31822c62b9","article-title":"Activation of NK cells by ADCC antibodies and HIV disease progression","volume":"58","author":"Chung","year":"2011","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"10.1016\/j.jim.2012.07.006_bb0065","first-page":"373","article-title":"HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC)","volume":"17","author":"Cox","year":"1999","journal-title":"Methods Mol. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0070","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1089\/088922299310755","article-title":"Antibody-dependent cellular cytotoxicity in HIV type 1-infected patients receiving VaxSyn, a recombinant gp160 envelope vaccine","volume":"15","author":"Cox","year":"1999","journal-title":"AIDS Res. Hum. Retroviruses"},{"issue":"2","key":"10.1016\/j.jim.2012.07.006_bb0075","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.virol.2011.03.012","article-title":"Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals","volume":"415","author":"Dugast","year":"2011","journal-title":"Virology"},{"key":"10.1016\/j.jim.2012.07.006_bb0080","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.4049\/jimmunol.0803115","article-title":"Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat\/Env compared with multigenic vaccines","volume":"182","author":"Florese","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0090","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.4049\/jimmunol.174.4.2185","article-title":"Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251","volume":"174","author":"G\u00f3mez-Rom\u00e1n","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0085","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jim.2005.09.018","article-title":"A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity","volume":"308","author":"G\u00f3mez-Rom\u00e1n","year":"2006","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jim.2012.07.006_bb0095","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1056\/NEJMoa1113425","article-title":"Immune-correlates analysis of an HIV-1 vaccine efficacy trial","volume":"366","author":"Haynes","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0100","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature06106","article-title":"Fc receptor but not complement binding is important in antibody protection against HIV","volume":"449","author":"Hessell","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jim.2012.07.006_bb0105","doi-asserted-by":"crossref","first-page":"12161","DOI":"10.1128\/JVI.75.24.12161-12168.2001","article-title":"Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1","volume":"75","author":"Hezareh","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.jim.2012.07.006_bb0110","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1128\/JVI.01672-08","article-title":"Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques","volume":"83","author":"Hidajat","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.jim.2012.07.006_bb0115","doi-asserted-by":"crossref","first-page":"337","DOI":"10.4049\/jimmunol.179.1.337","article-title":"Intimate cell conjugate formation and exchange of membrane lipids precede apoptosis induction in target cells during antibody-dependent, granulocyte-mediated cytotoxicity","volume":"179","author":"Horner","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0120","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1365-2796.2007.01819.x","article-title":"Humoral immunity to HIV-1: neutralization and beyond","volume":"262","author":"Huber","year":"2007","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0125","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.4049\/jimmunol.178.5.3099","article-title":"A novel antibody-dependent cellular cytotoxicity mechanism involved in defense against malaria requires costimulation of monocytes FcgammaRII and FcgammaRIII","volume":"178","author":"Jafarshad","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0130","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1089\/vim.2011.0025","article-title":"NK cell function and antibodies mediating ADCC in HIV-1-infected viremic and controller patients","volume":"24","author":"Johansson","year":"2011","journal-title":"Viral Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0135","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1128\/iai.41.1.219-223.1983","article-title":"Cooperation between antibodies and monocytes that inhibit in vitro proliferation of Plasmodium falciparum","volume":"41","author":"Khusmith","year":"1983","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jim.2012.07.006_bb0140","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1097\/QAD.0b013e328329f97d","article-title":"Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers","volume":"23","author":"Lambotte","year":"2009","journal-title":"AIDS"},{"key":"10.1016\/j.jim.2012.07.006_bb0145","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1128\/iai.57.7.2043-2049.1989","article-title":"Effector cells involved in nonspecific and antibody-dependent mechanisms directed against Plasmodium falciparum blood stages in vitro","volume":"57","author":"Lunel","year":"1989","journal-title":"Infect. Immun."},{"key":"10.1016\/j.jim.2012.07.006_bb0150","first-page":"e3588","article-title":"Determining the phagocytic activity of clinical antibody samples","author":"McAndrew","year":"2011","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.jim.2012.07.006_bb0155","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1086\/425582","article-title":"Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads","volume":"190","author":"Nag","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.jim.2012.07.006_bb0160","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.virol.2010.12.033","article-title":"Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge","volume":"411","author":"Patterson","year":"2011","journal-title":"Virology"},{"key":"10.1016\/j.jim.2012.07.006_bb0165","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/cyto.a.21084","article-title":"High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses","volume":"79","author":"Pollara","year":"2011","journal-title":"Cytometry A"},{"key":"10.1016\/j.jim.2012.07.006_bb0170","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1056\/NEJMoa0908492","article-title":"Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand","volume":"361","author":"Rerks-Ngarm","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jim.2012.07.006_bb0175","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1172\/JCI109236","article-title":"Human monocyte antibody-dependent cell-mediated cytotoxicity to tumor cells","volume":"62","author":"Shaw","year":"1978","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jim.2012.07.006_bb0180","doi-asserted-by":"crossref","first-page":"573","DOI":"10.4049\/jimmunol.121.2.573","article-title":"Human monocyte cytotoxicity to tumor cells. I. Antibody-dependent cytotoxicity","volume":"121","author":"Shaw","year":"1978","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0185","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0022-1759(00)00329-X","article-title":"A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis","volume":"249","author":"Sheehy","year":"2001","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jim.2012.07.006_bb0190","doi-asserted-by":"crossref","first-page":"5450","DOI":"10.1128\/JVI.01952-07","article-title":"Robust NK cell-mediated human immunodeficiency virus (HIV)-specific antibody-dependent responses in HIV-infected subjects","volume":"82","author":"Stratov","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.jim.2012.07.006_bb0195","doi-asserted-by":"crossref","first-page":"5914","DOI":"10.4049\/jimmunol.0900419","article-title":"Cutting Edge: Unusual NK cell responses to HIV-1 peptides are associated with protection against maternal-infant transmission of HIV-1","volume":"182","author":"Tiemessen","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2012.07.006_bb0200","doi-asserted-by":"crossref","first-page":"e13916","DOI":"10.1371\/journal.pone.0013916","article-title":"Profiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies","volume":"5","author":"Vaine","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jim.2012.07.006_bb0205","doi-asserted-by":"crossref","first-page":"4650","DOI":"10.1158\/1078-0432.CCR-07-4405","article-title":"lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells","volume":"14","author":"Wu","year":"2008","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jim.2012.07.006_bb0210","doi-asserted-by":"crossref","first-page":"7161","DOI":"10.1128\/JVI.00410-10","article-title":"Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian\/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques","volume":"84","author":"Xiao","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.jim.2012.07.006_bb0215","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.4049\/jimmunol.172.4.2401","article-title":"Antibody-dependent cellular cytotoxicity via humoral immune epitope of Nef protein expressed on cell surface","volume":"172","author":"Yamada","year":"2004","journal-title":"J. Immunol."}],"container-title":["Journal of Immunological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175912002001?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175912002001?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T16:32:44Z","timestamp":1758299564000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022175912002001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":43,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0022175912002001"],"URL":"https:\/\/doi.org\/10.1016\/j.jim.2012.07.006","relation":{},"ISSN":["0022-1759"],"issn-type":[{"value":"0022-1759","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity","name":"articletitle","label":"Article Title"},{"value":"Journal of Immunological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jim.2012.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}