{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T22:37:25Z","timestamp":1791153445816,"version":"4.1.0"},"reference-count":101,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Council of Scientific and Industrial Research (CSIR)"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Immunological Methods"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1016\/j.jim.2015.03.017","type":"journal-article","created":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T13:12:01Z","timestamp":1428412321000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":139,"special_numbering":"C","title":["Vaccines for visceral leishmaniasis: A review"],"prefix":"10.1016","volume":"422","author":[{"given":"Keerti","family":"Jain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.K.","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jim.2015.03.017_bb0005","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.exppara.2010.12.007","article-title":"Evaluation of DNA\/DNA and prime-boost vaccination using LPG3 against Leishmania major infection in susceptible BALB\/c mice and its antigenic properties in human leishmaniasis","volume":"127","author":"Abdian","year":"2011","journal-title":"Exp. Parasitol."},{"issue":"31","key":"10.1016\/j.jim.2015.03.017_bb0375","doi-asserted-by":"crossref","first-page":"5053","DOI":"10.1016\/j.vaccine.2011.04.089","article-title":"Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis","volume":"29","author":"Agallou","year":"2011","journal-title":"Vaccine"},{"issue":"34","key":"10.1016\/j.jim.2015.03.017_bb0200","doi-asserted-by":"crossref","first-page":"5086","DOI":"10.1016\/j.vaccine.2012.05.075","article-title":"Vaccination with Leishmania histone H1-pulsed dendritic cells confers protection in murine visceral leishmaniasis","volume":"30","author":"Agallou","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2015.03.017_bb0085","doi-asserted-by":"crossref","first-page":"660","DOI":"10.3389\/fimmu.2014.00660","article-title":"Targeted immunology for prevention and cure of VL","volume":"5","author":"Ali","year":"2014","journal-title":"Front. Immunol."},{"issue":"Suppl. 2","key":"10.1016\/j.jim.2015.03.017_bb0080","doi-asserted-by":"crossref","first-page":"B244","DOI":"10.1016\/j.vaccine.2012.11.080","article-title":"Case study for a vaccine against leishmaniasis","volume":"31","author":"Alvar","year":"2013","journal-title":"Vaccine"},{"issue":"18","key":"10.1016\/j.jim.2015.03.017_bb0165","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.vaccine.2008.02.044","article-title":"Despite Leishvaccine and Leishmune trigger distinct immune profiles, their ability to activate phagocytes and CD8+ T-cells support their high-quality immunogenic potential against canine visceral leishmaniasis","volume":"26","author":"Araujo","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2015.03.017_bb0120","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.vetimm.2011.02.007","article-title":"Immunological changes in canine peripheral blood leukocytes triggered by immunization with first or second generation vaccines against canine visceral leishmaniasis","volume":"141","author":"Ara\u00fajo","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0255","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijpharm.2013.08.037","article-title":"Alginate coated chitosan core shell nanoparticles for oral delivery of enoxaparin: in vitro and in vivo assessment","volume":"456","author":"Bagre","year":"2013","journal-title":"Int. J. Pharm."},{"issue":"11","key":"10.1016\/j.jim.2015.03.017_bb0105","doi-asserted-by":"crossref","first-page":"7160","DOI":"10.4049\/jimmunol.174.11.7160","volume":"174","author":"Basu","year":"2005","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.jim.2015.03.017_bb0110","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1086\/513439","article-title":"HLA class I-restricted T cell epitopes of the kinetoplastid membrane protein-11 presented by Leishmania donovani-infected human macrophages","volume":"195","author":"Basu","year":"2007","journal-title":"J. Infect. Dis."},{"issue":"3-4","key":"10.1016\/j.jim.2015.03.017_bb0145","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.vetpar.2013.05.008","article-title":"Vaccination with LiESP\/QA-21 (CaniLeish\u00ae) reduces the intensity of infection in Phlebotomus perniciosus fed on Leishmania infantum infected dogs \u2014 a preliminary xenodiagnosis study","volume":"197","author":"Bongiorno","year":"2013","journal-title":"Vet. Parasitol."},{"issue":"27-28","key":"10.1016\/j.jim.2015.03.017_bb0500","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1016\/S0264-410X(02)00294-3","article-title":"Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (S\u00e3o Gon\u00e7alo do Amarante, RN)","volume":"20","author":"Borja-Cabrera","year":"2002","journal-title":"Vaccine"},{"issue":"1-3","key":"10.1016\/j.jim.2015.03.017_bb0480","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.vetimm.2008.10.309","article-title":"Effective humoral and cellular immunoprotective responses in LiESAp-MDP vaccinated protected dogs","volume":"128","author":"Bourdoiseau","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"10","key":"10.1016\/j.jim.2015.03.017_bb0310","doi-asserted-by":"crossref","first-page":"6372","DOI":"10.1128\/IAI.73.10.6372-6382.2005","article-title":"Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis","volume":"73","author":"Breton","year":"2005","journal-title":"Infect. Immun."},{"issue":"7","key":"10.1016\/j.jim.2015.03.017_bb0465","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.vaccine.2008.11.094","article-title":"A prime\/boost DNA\/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis","volume":"27","author":"Carson","year":"2009","journal-title":"Vaccine"},{"issue":"19","key":"10.1016\/j.jim.2015.03.017_bb0205","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1016\/j.vaccine.2011.02.096","article-title":"A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis","volume":"29","author":"Chakravarty","year":"2011","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0090","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.imbio.2012.02.008","article-title":"115kDa serine protease confers sustained protection to visceral leishmaniasis caused by Leishmania donovani via IFN-\u03b3 induced down-regulation of TNF-\u03b1 mediated MMP-9 activity","volume":"218","author":"Choudhury","year":"2013","journal-title":"Immunobiology"},{"issue":"2","key":"10.1016\/j.jim.2015.03.017_bb0130","doi-asserted-by":"crossref","first-page":"e0117247","DOI":"10.1371\/journal.pone.0117247","article-title":"The host-protective effect of arabinosylated lipoarabinomannan against Leishmania donovani infection is associated with restoration of IFN-\u03b3 responsiveness","volume":"10","author":"Chowdhury","year":"2015","journal-title":"PLoS One"},{"issue":"9-10","key":"10.1016\/j.jim.2015.03.017_bb0505","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/S0264-410X(00)00339-X","article-title":"A phase III trial of efficacy of the FML-vaccine against canine kala-azar in an endemic area of Brazil (S\u00e3o Gon\u00e7alo do Amaranto, RN)","volume":"19","author":"Da Silva","year":"2000","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0230","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.actatropica.2011.08.007","article-title":"DNA vaccination with KMP11 and Lutzomyia longipalpis salivary protein protects hamsters against visceral leishmaniasis","volume":"120","author":"da Silva","year":"2011","journal-title":"Acta Trop."},{"issue":"10","key":"10.1016\/j.jim.2015.03.017_bb0300","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1086\/374783","article-title":"Leishmania mexicana and Leishmania major: attenuation of wild-type parasites and vaccination with the attenuated lines","volume":"187","author":"Daneshvar","year":"2003","journal-title":"J. Infect. Dis."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0475","doi-asserted-by":"crossref","first-page":"e2757","DOI":"10.1371\/journal.pntd.0002757","article-title":"Gentamicin-attenuated Leishmania infantum vaccine: protection of dogs against canine visceral leishmaniosis in endemic area of southeast of Iran","volume":"8","author":"Daneshvar","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0175","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.exppara.2011.10.001","article-title":"Radio-attenuated leishmanial parasites as immunoprophylactic agent against experimental murine visceral leishmaniasis","volume":"130","author":"Datta","year":"2012","journal-title":"Exp. Parasitol."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0180","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.bjid.2014.10.009","article-title":"Therapy with radio-attenuated vaccine in experimental murine visceral leishmaniasis showed enhanced T cell and inducible nitric; oxide synthase levels, suppressed tumor growth factor-beta production with higher expression of some signaling molecules","volume":"19","author":"Datta","year":"2015","journal-title":"Braz. J. Infect. Dis."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0040","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.parint.2009.07.013","article-title":"Challenges and perspectives in vaccination against leishmaniasis","volume":"58","author":"De Oliveira","year":"2009","journal-title":"Parasitol. Int."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0210","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.exppara.2010.06.011","article-title":"Leishmania infantum chagasi: a genome-based approach to identification of excreted\/secreted proteins","volume":"126","author":"DebRoy","year":"2010","journal-title":"Exp. Parasitol."},{"issue":"5","key":"10.1016\/j.jim.2015.03.017_bb0385","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.4049\/jimmunol.1202801","article-title":"Live attenuated Leishmania donovani p27 gene knockout parasites are nonpathogenic and elicit long-term protective immunity in BALB\/c mice","volume":"190","author":"Dey","year":"2013","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.jim.2015.03.017_bb0335","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.4161\/hv.21881","article-title":"Immunogenicity and immune modulatory effects of in silico predicted L. donovani candidate peptide vaccines","volume":"8","author":"Elfaki","year":"2012","journal-title":"Hum. Vaccine Immunother."},{"issue":"7","key":"10.1016\/j.jim.2015.03.017_bb0125","doi-asserted-by":"crossref","first-page":"e2914","DOI":"10.1371\/journal.pntd.0002914","article-title":"Immune regulation during chronic visceral leishmaniasis","volume":"8","author":"Faleiro","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0195","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.mib.2012.05.002","article-title":"Making an anti-amastigote vaccine for visceral leishmaniasis: rational, update and perspectives","volume":"15","author":"Fernandes","year":"2012","journal-title":"Curr. Opin. Microbiol."},{"issue":"11","key":"10.1016\/j.jim.2015.03.017_bb0470","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.vaccine.2013.12.046","article-title":"Comparison of two commercial vaccines against visceral leishmaniasis in dogs from endemic areas: IgG, and subclasses, parasitism, and parasite transmission by xenodiagnosis","volume":"32","author":"Fernandes","year":"2014","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.jim.2015.03.017_bb0355","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.vaccine.2007.11.044","article-title":"Immunization with the cysteine proteinase Ldccys1 gene from Leishmania (Leishmania) chagasi and the recombinant Ldccys1 protein elicits protective immune responses in a murine model of visceral leishmaniasis","volume":"26","author":"Ferreira","year":"2008","journal-title":"Vaccine"},{"issue":"22","key":"10.1016\/j.jim.2015.03.017_bb0435","doi-asserted-by":"crossref","first-page":"4863","DOI":"10.1016\/j.vaccine.2006.03.005","article-title":"Immunotherapy against visceral leishmaniasis with the nucleoside hydrolase-DNA vaccine of Leishmania donovani","volume":"24","author":"Gamboa-Leon","year":"2006","journal-title":"Vaccine"},{"issue":"22","key":"10.1016\/j.jim.2015.03.017_bb0225","doi-asserted-by":"crossref","first-page":"7845","DOI":"10.1073\/pnas.0712153105","article-title":"Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model","volume":"105","author":"Gomes","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"42","key":"10.1016\/j.jim.2015.03.017_bb0390","doi-asserted-by":"crossref","first-page":"7450","DOI":"10.1016\/j.vaccine.2007.08.001","article-title":"Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant","volume":"25","author":"Goto","year":"2007","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0215","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.exppara.2012.04.022","article-title":"Identification of Th1-responsive leishmanial excretory\u2013secretory antigens (LESAs)","volume":"132","author":"Gour","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.jim.2015.03.017_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2015.01.003","article-title":"Canine Leishmania vaccines: still a long way to go","author":"Gradoni","year":"2015","journal-title":"Vet. Parasitol."},{"issue":"15","key":"10.1016\/j.jim.2015.03.017_bb0455","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1016\/j.vaccine.2013.02.025","volume":"31","author":"Guha","year":"2013","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.jim.2015.03.017_bb0190","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ijpara.2012.02.013","article-title":"A novel recombinant Leishmania donovani p45, a partial coding region of methionine aminopeptidase, generates protective immunity by inducing a Th1 stimulatory response against experimental visceral leishmaniasis","volume":"42","author":"Gupta","year":"2012","journal-title":"Int. J. Parasitol."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0060","doi-asserted-by":"crossref","first-page":"e3321","DOI":"10.1371\/journal.pntd.0003321","article-title":"Th1-biased immunomodulation and therapeutic potential of Artemisia annua in murine visceral leishmaniasis","volume":"9","author":"Islamuddin","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"23-24","key":"10.1016\/j.jim.2015.03.017_bb0025","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.drudis.2013.08.005","article-title":"Novel therapeutic strategies for treatment of visceral leishmaniasis","volume":"18","author":"Jain","year":"2013","journal-title":"Drug Discov. Today"},{"issue":"16","key":"10.1016\/j.jim.2015.03.017_bb0245","doi-asserted-by":"crossref","first-page":"4166","DOI":"10.1016\/j.biomaterials.2012.02.033","article-title":"A review of glycosylated carriers for drug delivery","volume":"33","author":"Jain","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.jim.2015.03.017_bb0260","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1007\/s11051-013-1888-7","article-title":"Low density lipoproteins mediated nanoplatforms for cancer targeting","volume":"15","author":"Jain","year":"2013","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.jim.2015.03.017_bb0250","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.coph.2014.01.006","article-title":"Potentials and emerging trends in nanopharmacology","volume":"15C","author":"Jain","year":"2014","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.jim.2015.03.017_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.nano.2014.11.008","article-title":"Characterization and evaluation of amphotericin B loaded MDP conjugated poly(propylene imine) dendrimers","author":"Jain","year":"2015","journal-title":"Nanomedicine"},{"key":"10.1016\/j.jim.2015.03.017_bb0070","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.04213-14","article-title":"Surface engineered dendrimeric nanoconjugates for macrophage targeted delivery of amphotericin B: formulation development, in vitro and in vivo evaluation","author":"Jain","year":"2015","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0170","first-page":"26","article-title":"Immunotherapy using autoclaved L. major antigens and M. vaccae with Meglumine antimoniate, for the treatment of experimental canine visceral leishmaniasis","volume":"6","author":"Jamshidi","year":"2011","journal-title":"Iran. J. Parasitol."},{"issue":"9761","key":"10.1016\/j.jim.2015.03.017_bb0010","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0140-6736(10)61265-2","article-title":"Continuing challenge of infectious diseases in India","volume":"377","author":"John","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.jim.2015.03.017_bb0285","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3389\/fimmu.2014.00380","article-title":"Visceral leishmaniasis: advancements in vaccine development via classical and molecular approaches","volume":"5","author":"Joshi","year":"2014","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0495","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0035-9203(03)90171-4","article-title":"Alum-precipitated autoclaved Leishmania major plus Bacille Calmette\u2013Gu\u00e9rrin, a candidate vaccine for visceral leishmaniasis: safety, skin-delayed type hypersensitivity response and dose finding in healthy volunteers","volume":"97","author":"Kamil","year":"2003","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"2","key":"10.1016\/j.jim.2015.03.017_bb0405","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s12639-012-0171-7","article-title":"Protective immunity using MPL-A and autoclaved Leishmania donovani as adjuvants along with a cocktail vaccine in murine model of visceral leishmaniasis","volume":"37","author":"Kaur","year":"2013","journal-title":"J. Parasit. Dis."},{"key":"10.1016\/j.jim.2015.03.017_bb0290","doi-asserted-by":"crossref","DOI":"10.1111\/pim.12176","article-title":"Studies on cocktails of 31kDa, 36kDa and 51kDa antigens of Leishmania donovani along with saponin against murine visceral leishmaniasis","author":"Kaur","year":"2015","journal-title":"Parasite Immunol."},{"issue":"10","key":"10.1016\/j.jim.2015.03.017_bb0030","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1111\/j.1469-0691.2011.03610.x","article-title":"Visceral leishmaniasis: immunology and prospects for a vaccine","volume":"17","author":"Kaye","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"issue":"2","key":"10.1016\/j.jim.2015.03.017_bb0265","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.progpolymsci.2013.07.005","article-title":"Dendrimer as nanocarrier for drug delivery","volume":"39","author":"Kesharwani","year":"2014","journal-title":"Prog. Polym. Sci."},{"issue":"9241","key":"10.1016\/j.jim.2015.03.017_bb0510","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/S0140-6736(00)03128-7","article-title":"Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan","volume":"356","author":"Khalil","year":"2000","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0320","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1179\/146532806X152890","article-title":"Safety and immunogenicity of a candidate vaccine for visceral leishmaniasis (alum-precipitated autoclaved Leishmania major+BCG) in children: an extended phase II study","volume":"26","author":"Khalil","year":"2006","journal-title":"Ann. Trop. Paediatr."},{"issue":"46","key":"10.1016\/j.jim.2015.03.017_bb0450","doi-asserted-by":"crossref","first-page":"5822","DOI":"10.1016\/j.vaccine.2008.08.065","article-title":"Cysteine proteinase type III is protective against Leishmania infantum infection in BALB\/c mice and highly antigenic in visceral leishmaniasis individuals","volume":"26","author":"Khoshgoo","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2015.03.017_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.parint.2015.01.004","article-title":"Proteomic analyses of membrane enriched proteins of Leishmania donovani Indian clinical isolate by mass spectrometry","author":"Kumar","year":"2015","journal-title":"Parasitol. Int."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0315","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/eji.200838389","article-title":"Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis","volume":"39","author":"Kumari","year":"2009","journal-title":"Eur. J. Immunol."},{"issue":"12","key":"10.1016\/j.jim.2015.03.017_bb0365","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.4049\/jimmunol.1102081","article-title":"Elongation factor-2, a Th1 stimulatory protein of Leishmania donovani, generates strong IFN-\u03b3 and IL-12 response in cured Leishmania-infected patients\/hamsters and protects hamsters against Leishmania challenge","volume":"187","author":"Kushawaha","year":"2011","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0370","doi-asserted-by":"crossref","first-page":"e35670","DOI":"10.1371\/journal.pone.0035670","article-title":"Evaluation of leishmania donovani protein disulfide isomerase as a potential immunogenic protein\/vaccine candidate against visceral leishmaniasis","volume":"7","author":"Kushawaha","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0075","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4269\/ajtmh.2012.10-0415","article-title":"The economic value of a visceral leishmaniasis vaccine in Bihar state, India","volume":"86","author":"Lee","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"21","key":"10.1016\/j.jim.2015.03.017_bb0350","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1016\/j.vaccine.2007.02.083","article-title":"Long-lasting protection against canine visceral leishmaniasis using the LiESAp-MDP vaccine in endemic areas of France: double-blind randomised efficacy field trial","volume":"25","author":"Lemesre","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2015.03.017_bb0160","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1297-9716-45-69","article-title":"The protective immune response produced in dogs after primary vaccination with the LiESP\/QA-21 vaccine (CaniLeish\u00ae) remains effective against an experimental challenge one year later","volume":"45","author":"Martin","year":"2014","journal-title":"Vet. Res."},{"key":"10.1016\/j.jim.2015.03.017_bb0220","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.actatropica.2013.02.008","article-title":"Identifying salivary antigens of Phlebotomus argentipes by a 2DE approach","volume":"126","author":"Martin-Martin","year":"2013","journal-title":"Acta Trop."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0410","doi-asserted-by":"crossref","first-page":"e2148","DOI":"10.1371\/journal.pntd.0002148","article-title":"Antigenicity and protective efficacy of a Leishmania amastigote-specific protein, member of the super-oxygenase family, against visceral leishmaniasis","volume":"7","author":"Martins","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jim.2015.03.017_bb0240","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.exppara.2011.05.014","article-title":"Efficacy of Leishmania donovani ribosomal P1 gene as DNA vaccine in experimental visceral leishmaniasis","volume":"129","author":"Masih","year":"2011","journal-title":"Exp. Parasitol."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0015","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S1473-3099(10)70320-0","article-title":"Visceral leishmaniasis: elimination with existing interventions","volume":"11","author":"Matlashewski","year":"2011","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.jim.2015.03.017_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.drudis.2015.01.006","article-title":"Pharmaceutical and biomedical applications of surface engineered carbon nanotubes","author":"Mehra","year":"2015","journal-title":"Drug Discov. Today"},{"issue":"29-30","key":"10.1016\/j.jim.2015.03.017_bb0490","doi-asserted-by":"crossref","first-page":"4097","DOI":"10.1016\/j.vaccine.2004.03.058","article-title":"Double-blind randomized efficacy field trial of alum precipitated autoclaved Leishmania major vaccine mixed with BCG against canine visceral leishmaniasis in Meshkin-Shahr district, I.R. Iran","volume":"22","author":"Mohebali","year":"2004","journal-title":"Vaccine"},{"issue":"3-4","key":"10.1016\/j.jim.2015.03.017_bb0150","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.vetimm.2014.01.011","article-title":"Primary vaccination with the LiESP\/QA-21 vaccine (CaniLeish) produces a cell-mediated immune response which is still present 1year later","volume":"158","author":"Moreno","year":"2014","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0100","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.intimp.2012.02.002","article-title":"Miltefosine triggers a strong proinflammatory cytokine response during visceral leishmaniasis: role of TLR4 and TLR9","volume":"12","author":"Mukherjee","year":"2012","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0485","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.trstmh.2007.08.006","article-title":"Leishmaniasis Research Group\/Sudan. Immunochemotherapy of persistent post-kala-azar dermal leishmaniasis: a novel approach to treatment","volume":"102","author":"Musa","year":"2008","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.jim.2015.03.017_bb0035","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.intimp.2011.05.008","article-title":"Vaccine candidates for leishmaniasis: a review","volume":"11","author":"Nagill","year":"2011","journal-title":"Int. Immunopharmacol."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0325","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.parint.2009.07.008","article-title":"Induction of cellular and humoral responses by autoclaved and heat-killed antigen of Leishmania donovani in experimental visceral leishmaniasis","volume":"58","author":"Nagill","year":"2009","journal-title":"Parasitol. Int."},{"issue":"21","key":"10.1016\/j.jim.2015.03.017_bb0185","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.1016\/j.vaccine.2012.03.006","article-title":"The adjuvanticity of Chiococca alba saponins increases with the length and hydrophilicity of their sugar chains","volume":"30","author":"Nico","year":"2012","journal-title":"Vaccine"},{"issue":"18","key":"10.1016\/j.jim.2015.03.017_bb0340","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1016\/j.vaccine.2006.02.034","article-title":"Acylated and deacylated saponins of Quillaja saponaria mixture as adjuvants for the FML-vaccine against visceral leishmaniasis","volume":"24","author":"Oliveira-Freitas","year":"2006","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0305","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1128\/IAI.70.1.62-68.2002","article-title":"Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination","volume":"70","author":"Papadopoulou","year":"2002","journal-title":"Infect. Immun."},{"issue":"23-24","key":"10.1016\/j.jim.2015.03.017_bb0345","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1016\/S0264-410X(01)00031-7","article-title":"Vaccination of Balb\/c mice against experimental visceral leishmaniasis with the GP36 glycoprotein antigen of Leishmania donovani","volume":"19","author":"Paraguai de Souza","year":"2001","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.jim.2015.03.017_bb0235","doi-asserted-by":"crossref","first-page":"e0003490","DOI":"10.1371\/journal.pntd.0003490","article-title":"Vaccination with Leishmania infantum acidic ribosomal P0 but not with nucleosomal histones proteins controls Leishmania infantum infection in hamsters","volume":"10","author":"Pereira","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jim.2015.03.017_bb0115","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.intimp.2012.03.016","article-title":"Miltefosine enhances phagocytosis but decreases nitric oxide production by peritoneal macrophages of C57BL\/6 mice","volume":"13","author":"Ponte","year":"2012","journal-title":"Int. Immunopharmacol."},{"issue":"12","key":"10.1016\/j.jim.2015.03.017_bb0445","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1016\/j.vaccine.2005.11.011","article-title":"Prime-boost vaccination using cysteine proteinases type I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis","volume":"24","author":"Rafati","year":"2006","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.jim.2015.03.017_bb0440","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.vaccine.2007.11.021","article-title":"Heterologous prime-boost vaccination with a non-replicative vaccinia recombinant vector expressing LACK confers protection against canine visceral leishmaniasis with a predominant Th1-specific immune response","volume":"26","author":"Ramos","year":"2008","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jim.2015.03.017_bb0360","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1021\/mp2002494","article-title":"Vaccination with liposomal leishmanial antigens adjuvanted with monophosphoryl lipid-trehalose dicorynomycolate (MPL-TDM) confers long-term protection against visceral leishmaniasis through a human administrable route","volume":"9","author":"Ravindran","year":"2012","journal-title":"Mol. Pharm."},{"issue":"3-4","key":"10.1016\/j.jim.2015.03.017_bb0395","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.vetpar.2013.09.011","article-title":"Cytokine and nitric oxide patterns in dogs immunized with LBSap vaccine, before and after experimental challenge with Leishmania chagasi plus saliva of Lutzomyia longipalpis","volume":"198","author":"Resende","year":"2013","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.jim.2015.03.017_bb0050","doi-asserted-by":"crossref","first-page":"272","DOI":"10.3389\/fimmu.2014.00272","article-title":"Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease","volume":"5","author":"Roatt","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jim.2015.03.017_bb0095","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1016\/j.intimp.2011.08.002","article-title":"Immunomodulation by chemotherapeutic agents against Leishmaniasis","volume":"11","author":"Saha","year":"2011","journal-title":"Int. Immunopharmacol."},{"issue":"12","key":"10.1016\/j.jim.2015.03.017_bb0275","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/pim.12042","article-title":"Cationic solid\u2013lipid nanoparticles are as efficient as electroporation in DNA vaccination against visceral leishmaniasis in mice","volume":"35","author":"Saljoughian","year":"2013","journal-title":"Parasite Immunol."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0280","doi-asserted-by":"crossref","first-page":"e2174","DOI":"10.1371\/journal.pntd.0002174","article-title":"Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis","volume":"7","author":"Saljoughian","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jim.2015.03.017_bb0430","first-page":"2115","article-title":"Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11","volume":"7","author":"Santos","year":"2012","journal-title":"Int. J. Nanomedicine"},{"issue":"15-16","key":"10.1016\/j.jim.2015.03.017_bb0330","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/S0264-410X(00)00401-1","article-title":"Immunogenicity and safety of autoclaved Leishmania major plus BCG vaccine in healthy Sudanese volunteers","volume":"19","author":"Satti","year":"2001","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.jim.2015.03.017_bb0295","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.4049\/jimmunol.179.5.3161","article-title":"SIR2-deficient Leishmania infantum induces a defined IFN-gamma\/IL-10 pattern that correlates with protection","volume":"179","author":"Silvestre","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.jim.2015.03.017_bb0135","doi-asserted-by":"crossref","first-page":"3834","DOI":"10.1016\/j.vaccine.2012.03.068","article-title":"Leishmaniasis: vaccine candidates and perspectives","volume":"30","author":"Singh","year":"2012","journal-title":"Vaccine"},{"issue":"10","key":"10.1016\/j.jim.2015.03.017_bb0140","doi-asserted-by":"crossref","first-page":"e1874","DOI":"10.1371\/journal.pntd.0001874","article-title":"Cytokine responses to novel antigens in an Indian population living in an area endemic for visceral leishmaniasis","volume":"6","author":"Singh","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"16","key":"10.1016\/j.jim.2015.03.017_bb0425","doi-asserted-by":"crossref","first-page":"832","DOI":"10.6026\/97320630009832","article-title":"A comprehensive analysis of LACK (Leishmania homologue of receptors for activated C kinase) in the context of visceral leishmaniasis","volume":"9","author":"Sinha","year":"2013","journal-title":"Bioinformation"},{"issue":"6","key":"10.1016\/j.jim.2015.03.017_bb0020","doi-asserted-by":"crossref","first-page":"e2278","DOI":"10.1371\/journal.pntd.0002278","article-title":"A review of preventative methods against human leishmaniasis infection","volume":"7","author":"Stockdale","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"11-12","key":"10.1016\/j.jim.2015.03.017_bb0415","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/S0264-410X(02)00352-3","article-title":"Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani","volume":"21","author":"Sukumaran","year":"2003","journal-title":"Vaccine"},{"issue":"19","key":"10.1016\/j.jim.2015.03.017_bb0380","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1016\/j.vaccine.2010.02.089","article-title":"Treatment of canine visceral leishmaniasis by the vaccine Leish-111f+MPL-SE","volume":"28","author":"Trigo","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.jim.2015.03.017_bb0045","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.idc.2012.03.005","article-title":"Visceral leishmaniasis","volume":"26","author":"Van Griensven","year":"2012","journal-title":"Infect. Dis. Clin. North Am."},{"issue":"4","key":"10.1016\/j.jim.2015.03.017_bb0400","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.molimm.2013.05.231","article-title":"Dogs immunized with LBSap vaccine displayed high levels of IL-12 and IL-10 cytokines and CCL4, CCL5 and CXCL8 chemokines in the dermis","volume":"56","author":"Vitoriano-Souza","year":"2013","journal-title":"Mol. Immunol."},{"issue":"Pt 9","key":"10.1016\/j.jim.2015.03.017_bb0420","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1099\/jmm.0.029959-0","article-title":"Generation and evaluation of A2-expressing Lactococcus lactis live vaccines against Leishmania donovani in BALB\/c mice","volume":"60","author":"Yam","year":"2011","journal-title":"J. Med. Microbiol."}],"container-title":["Journal of Immunological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175915000939?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175915000939?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T16:00:00Z","timestamp":1537718400000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022175915000939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":101,"alternative-id":["S0022175915000939"],"URL":"https:\/\/doi.org\/10.1016\/j.jim.2015.03.017","relation":{},"ISSN":["0022-1759"],"issn-type":[{"value":"0022-1759","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vaccines for visceral leishmaniasis: A review","name":"articletitle","label":"Article Title"},{"value":"Journal of Immunological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jim.2015.03.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}