{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:23:35Z","timestamp":1778775815868,"version":"3.51.4"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Immunological Methods"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jim.2025.114019","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:30:28Z","timestamp":1764808228000},"page":"114019","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Development and clinical application of component-resolved diagnostic using light-initiated chemiluminescence assay to characterize house dust mite components-specific IgE"],"prefix":"10.1016","volume":"546","author":[{"given":"Qinqin","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanmin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiqiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0005","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1159\/000447694","article-title":"Real-life study for the diagnosis of house dust mite allergy - the value of recombinant allergen-based IgE serology","volume":"170","author":"Becker","year":"2016","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"5","key":"10.1016\/j.jim.2025.114019_bb0010","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1007\/s00216-017-0791-y","article-title":"Development of a light-initiated chemiluminescent assay for the quantitation of sIgE against egg white allergens based on component-resolved diagnosis","volume":"410","author":"Bian","year":"2018","journal-title":"Anal. Bioanal. Chem."},{"issue":"12","key":"10.1016\/j.jim.2025.114019_bib179","doi-asserted-by":"crossref","first-page":"adv00160","DOI":"10.2340\/00015555-3510","article-title":"Prevalence and incidence of atopic dermatitis: a systematic review","volume":"100","author":"Bylund","year":"2020","journal-title":"Acta Derm. Venereol."},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0015","doi-asserted-by":"crossref","DOI":"10.3390\/nu13020640","article-title":"Component-resolved diagnosis of hazelnut allergy in children","volume":"13","author":"Caffarelli","year":"2021","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jim.2025.114019_bb0020","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.aller.2018.02.008","article-title":"Sublingual immunotherapy of house dust mite respiratory allergy in China","volume":"47","author":"Cheng","year":"2019","journal-title":"Allergol Immunopathol (Madr)"},{"issue":"3","key":"10.1016\/j.jim.2025.114019_bib180","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.jaci.2018.10.048","article-title":"Selection of house dust mite-allergic patients by molecular diagnosis may enhance success of specific immunotherapy","volume":"143","author":"Chen","year":"2019","journal-title":"J. Allergy Clin. Immunol."},{"issue":"4","key":"10.1016\/j.jim.2025.114019_bb0025","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4168\/aair.2018.10.4.300","article-title":"Chinese Society of Allergy Guidelines for diagnosis and treatment of allergic rhinitis","volume":"10","author":"Cheng","year":"2018","journal-title":"Allergy, Asthma Immunol. Res."},{"key":"10.1016\/j.jim.2025.114019_bb0030","series-title":"Evaluation of Precision Performance of Quantitative Measurement Methods","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2004"},{"issue":"5","key":"10.1016\/j.jim.2025.114019_bb0035","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1373\/jalm.2018.026526","article-title":"Component-resolved diagnosis in allergic rhinitis and asthma","volume":"3","author":"Eiringhaus","year":"2019","journal-title":"J. Appl. Lab. Med."},{"key":"10.1016\/j.jim.2025.114019_bib178","doi-asserted-by":"crossref","first-page":"1215616","DOI":"10.3389\/falgy.2023.1215616","article-title":"Immunologic, genetic, and ecological interplay of factors involved in allergic diseases","volume":"4","author":"Falcon","year":"2023","journal-title":"Front. Allergy"},{"issue":"1","key":"10.1016\/j.jim.2025.114019_bb0040","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jaip.2020.09.037","article-title":"Improving diagnostic accuracy in food allergy","volume":"9","author":"Foong","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0045","doi-asserted-by":"crossref","DOI":"10.1111\/pai.13829","article-title":"Der p 23-specific IgE response throughout childhood and its association with allergic disease: a birth cohort study","volume":"33","author":"Forchert","year":"2022","journal-title":"Pediatr. Allergy Immunol."},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0050","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/cea.14255","article-title":"House dust mite components sensitization profile in China, a multi-centre study","volume":"53","author":"Gan","year":"2023","journal-title":"Clin. Exp. Allergy"},{"issue":"12","key":"10.1016\/j.jim.2025.114019_bb0055","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1111\/apa.13515","article-title":"The allergic march comprises the coexistence of related patterns of allergic disease not just the progressive development of one disease","volume":"105","author":"Goksor","year":"2016","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.jim.2025.114019_bb0060","article-title":"Prevalence of atopic dermatitis in Chinese children aged 1-7 ys","volume":"6","author":"Guo","year":"2016","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0065","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000504320","article-title":"Identifying potential co-sensitization and cross-reactivity patterns based on component-resolved diagnosis","volume":"181","author":"Huang","year":"2020","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.jim.2025.114019_bb0070","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.molimm.2023.04.008","article-title":"House dust mite allergy: the importance of house dust mite allergens for diagnosis and immunotherapy","volume":"158","author":"Huang","year":"2023","journal-title":"Mol. Immunol."},{"issue":"6","key":"10.1016\/j.jim.2025.114019_bb0075","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1111\/all.15600","article-title":"National trends in the prevalence of allergic diseases among Korean adolescents before and during COVID-19, 2009-2021: a serial analysis of the national representative study","volume":"78","author":"Koo","year":"2023","journal-title":"Allergy"},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0080","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/all.12546","article-title":"The importance of EN ISO 15189 accreditation of allergen-specific IgE determination for reliable in vitro allergy diagnosis","volume":"70","author":"Lambert","year":"2015","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.jim.2025.114019_bb0085","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-69166-w","article-title":"Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy","volume":"10","author":"Lazaro-Gorines","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jim.2025.114019_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2025.113856","article-title":"A novel combination mode for inhalant allergen screening based on 8-well microplates by LiCA","volume":"540","author":"Li","year":"2025","journal-title":"J. Immunol. Methods"},{"issue":"5","key":"10.1016\/j.jim.2025.114019_bb0095","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1159\/000520511","article-title":"A simple and rapid light-initiated Chemiluminescence assay for quantitation of Artemisia-specific immunoglobulin E","volume":"183","author":"Liu","year":"2022","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"3","key":"10.1016\/j.jim.2025.114019_bib177","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/MOO.0000000000000262","article-title":"Epidemiology of asthma","volume":"24","author":"Loftus","year":"2016","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0100","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1111\/all.14749","article-title":"Comparison of house dust mite sensitization profiles in allergic adults from Canada, Europe, South Africa and USA","volume":"76","author":"Muddaluru","year":"2021","journal-title":"Allergy"},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0105","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1515\/cclm-2022-0191","article-title":"A comprehensive comparison between ISAC and ALEX(2) multiplex test systems","volume":"60","author":"Platteel","year":"2022","journal-title":"Clin. Chem. Lab. Med."},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0110","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jaci.2016.08.014","article-title":"Evolution and predictive value of IgE responses toward a comprehensive panel of house dust mite allergens during the first 2 decades of life","volume":"139","author":"Posa","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"issue":"10","key":"10.1016\/j.jim.2025.114019_bb0115","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1111\/all.15327","article-title":"Molecular reactivity profiling upon immunotherapy with a 300 IR sublingual house dust mite tablet reveals marked humoral changes towards major allergens","volume":"77","author":"Potapova","year":"2022","journal-title":"Allergy"},{"issue":"1","key":"10.1016\/j.jim.2025.114019_bb0120","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1038\/s41598-018-38313-9","article-title":"The major allergen Der p 2 is a cholesterol binding protein","volume":"9","author":"Reginald","year":"2019","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jim.2025.114019_bb0125","doi-asserted-by":"crossref","first-page":"79","DOI":"10.23822\/EurAnnACI.1764-1489.264","article-title":"Der p 23 sensitization in patients with house dust mite respiratory allergy","volume":"56","author":"Romero-Sanchez","year":"2024","journal-title":"Eur Ann Allergy Clin Immunol"},{"issue":"8","key":"10.1016\/j.jim.2025.114019_bb0130","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1111\/all.15807","article-title":"Global, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: a systematic analysis for the global burden of disease study 2019","volume":"78","author":"Shin","year":"2023","journal-title":"Allergy"},{"issue":"8","key":"10.1016\/j.jim.2025.114019_bb0135","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1056\/NEJM199008233230802","article-title":"Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study","volume":"323","author":"Sporik","year":"1990","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0140","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.24544","article-title":"Performance evaluation of a laboratory-developed light-initiated chemiluminescence assay for quantification of egg white-specific IgE","volume":"36","author":"Tan","year":"2022","journal-title":"J. Clin. Lab. Anal."},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0145","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.4049\/jimmunol.1202288","article-title":"Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets","volume":"190","author":"Weghofer","year":"2013","journal-title":"J. Immunol."},{"issue":"10","key":"10.1016\/j.jim.2025.114019_bb0150","doi-asserted-by":"crossref","DOI":"10.1111\/pim.13007","article-title":"Dot-ELISA based on recombinant Hypodermin C of Przhevalskiana silenus for field diagnosis of goat warble fly infestation","volume":"45","author":"Yadav","year":"2023","journal-title":"Parasite Immunol."},{"issue":"7\u20138","key":"10.1016\/j.jim.2025.114019_bb0155","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1080\/00365513.2018.1528506","article-title":"Comparison of allergen-specific IgE levels between Immulite 2000 and ImmunoCAP systems against six inhalant allergens and ten food allergens","volume":"78","author":"Yang","year":"2018","journal-title":"Scand. J. Clin. Lab. Invest."},{"issue":"7","key":"10.1016\/j.jim.2025.114019_bb0160","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1007\/s10653-019-00481-6","article-title":"Haze facilitates sensitization to house dust mites in children","volume":"42","author":"Ye","year":"2020","journal-title":"Environ. Geochem. Health"},{"issue":"1","key":"10.1016\/j.jim.2025.114019_bb0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12948-022-00182-z","article-title":"Molecular sensitization pattern to house dust mites is formed from the first years of life and includes group 1, 2, Der p 23, Der p 5, Der p 7 and Der p 21 allergens","volume":"21","author":"Yuriev","year":"2023","journal-title":"Clin. Mol. Allergy"},{"issue":"4","key":"10.1016\/j.jim.2025.114019_bb0170","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/all.15945","article-title":"Hot topics in allergen immunotherapy, 2023: current status and future perspective","volume":"79","author":"Zemelka-Wiacek","year":"2024","journal-title":"Allergy"},{"key":"10.1016\/j.jim.2025.114019_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2021.113209","article-title":"Development of a light-initiated chemiluminescence assay for the quantitative detection of cow's milk allergen-specific IgE","volume":"501","author":"Zhang","year":"2022","journal-title":"J. Immunol. Methods"}],"container-title":["Journal of Immunological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175925002194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175925002194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T17:25:40Z","timestamp":1767893140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022175925002194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":39,"alternative-id":["S0022175925002194"],"URL":"https:\/\/doi.org\/10.1016\/j.jim.2025.114019","relation":{},"ISSN":["0022-1759"],"issn-type":[{"value":"0022-1759","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and clinical application of component-resolved diagnostic using light-initiated chemiluminescence assay to characterize house dust mite components-specific IgE","name":"articletitle","label":"Article Title"},{"value":"Journal of Immunological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jim.2025.114019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114019"}}