{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T13:15:56Z","timestamp":1785244556061,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Immunological Methods"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jim.2026.114077","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T23:27:18Z","timestamp":1781566038000},"page":"114077","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Development of chimeric DGP-IgG antibodies as quality control for celiac disease diagnosis"],"prefix":"10.1016","volume":"549","author":[{"given":"Liang","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xufu","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chungen","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangming","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jim.2026.114077_bb0005","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1093\/clinchem\/47.11.2023","article-title":"Celiac disease: antibody recognition against native and selectively deamidated gliadin peptides","volume":"47","author":"Aleanzi","year":"2001","journal-title":"Clin. Chem."},{"issue":"4","key":"10.1016\/j.jim.2026.114077_bb0010","doi-asserted-by":"crossref","first-page":"312","DOI":"10.5223\/pghn.2022.25.4.312","article-title":"Diagnostic value of immunoglobulin G anti-deamidated gliadin peptide antibody for diagnosis of pediatric celiac disease: a study from Shiraz, Iran","volume":"25","author":"Anbardar","year":"2022","journal-title":"Pediatr. Gastroenterol. Hepatol. Nutr."},{"key":"10.1016\/j.jim.2026.114077_bb0015","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s13052-017-0392-6","article-title":"Coeliac disease in infants: antibodies to deamidated gliadin peptide come first!","volume":"43","author":"Arigliani","year":"2017","journal-title":"Ital. J. Pediatr."},{"key":"10.1016\/j.jim.2026.114077_bb0020","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1007\/s10620-017-4528-8","article-title":"The CD that pays dividends: more than 15 years of deamidated gliadin peptide antibodies","volume":"62","author":"Bai","year":"2017","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.jim.2026.114077_bb0025","doi-asserted-by":"crossref","first-page":"644","DOI":"10.3390\/nu8100644","article-title":"Properties of gluten intolerance: gluten structure, evolution, pathogenicity and detoxification capabilities","volume":"8","author":"Balakireva","year":"2016","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jim.2026.114077_bb0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S2213-8587(23)00354-6","article-title":"Screening type 1 diabetes and coeliac disease by law","volume":"12","author":"Bosi","year":"2024","journal-title":"Lancet Diab. Endocrinol."},{"key":"10.1016\/j.jim.2026.114077_bb0035","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1007\/s10620-017-4474-5","article-title":"Diagnostic yield of isolated deamidated gliadin peptide antibody elevation for celiac disease","volume":"62","author":"Hoerter","year":"2017","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.jim.2026.114077_bb0040","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1002\/1529-0131(199911)42:11<2461::AID-ANR25>3.0.CO;2-O","article-title":"A chimeric antibody with the human gamma1 constant region as a putative standard for assays to detect IgG beta2-glycoprotein I-dependent anticardiolipin and anti-beta2-glycoprotein I antibodies","volume":"42","author":"Ichikawa","year":"1999","journal-title":"Arth. Rheumat."},{"key":"10.1016\/j.jim.2026.114077_bb0045","unstructured":"iFlash-DGP IFU, YHLO Biotech."},{"key":"10.1016\/j.jim.2026.114077_bb0050","unstructured":"IFU and T042-Technical Bulletin of NanoDrop Spectrophotometers from Thermo Fisher."},{"key":"10.1016\/j.jim.2026.114077_bb0055","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1128\/CVI.00114-07","article-title":"Use of chimeric antibodies as positive controls in an enzyme-linked immunosorbent assay for diagnosis of scrub typhus (infection by Orientia tsutsugamushi)","volume":"14","author":"Jones","year":"2007","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.jim.2026.114077_bb0060","first-page":"1","article-title":"Incidence of celiac disease is increasing over time: a systematic review and Meta-analysis","volume":"00","author":"King","year":"2020","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.jim.2026.114077_bb0065","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/256495a0","article-title":"Continuous cultures of fused cells secreting antibody of predefined specificity","volume":"256","author":"Kohler","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.jim.2026.114077_bb0070","first-page":"626","article-title":"Antibodies to deamidated gliadin peptide in diagnosis of celiac disease in children","volume":"60","author":"Lammi","year":"2015","journal-title":"JPGN"},{"key":"10.1016\/j.jim.2026.114077_bb0075","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1155\/2013\/127589","article-title":"Celiac disease and autoimmune-associated conditions","volume":"2013","author":"Lauret","year":"2013","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.jim.2026.114077_bb0080","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1136\/gutjnl-2013-306578","article-title":"Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology","volume":"63","author":"Ludvigsson","year":"2014","journal-title":"Gut"},{"key":"10.1016\/j.jim.2026.114077_bb0085","first-page":"19.14.1","article-title":"Using biacore to measure the binding kinetics of an antibody-antigen interaction","author":"Murphy","year":"2006","journal-title":"Curr. Protoc. Protein Sci."},{"key":"10.1016\/j.jim.2026.114077_bb0090","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s13567-023-01213-6","article-title":"Development of a high-affinity anti-bovine PD-1 rabbit\u2013bovine chimeric antibody using an efficient selection and large production system","volume":"54","author":"Okagawa","year":"2023","journal-title":"Vet. Res."},{"issue":"10","key":"10.1016\/j.jim.2026.114077_bb0095","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/01.NPR.0000000000000232","article-title":"Celiac disease: guideline update overview","volume":"49","author":"Olmstead","year":"2024","journal-title":"Nurse Pract."},{"issue":"2","key":"10.1016\/j.jim.2026.114077_bb0100","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4291\/wjgp.v8.i2.27","article-title":"Celiac disease: from pathophysiology to treatment","volume":"8","author":"Parzanese","year":"2017","journal-title":"World J. Gastrointest. Pathophysiol."},{"key":"10.1016\/j.jim.2026.114077_bb0105","unstructured":"QUANTA Flash\u00ae DGP IgG IFU, Werfen."},{"key":"10.1016\/j.jim.2026.114077_bb0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.14309\/ajg.0000000000002075","article-title":"American College of Gastroenterology guidelines update: diagnosis and management of celiac disease","volume":"118","author":"Rubio-Tapia","year":"2023","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.jim.2026.114077_bb0115","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.cgh.2017.06.037","article-title":"Global prevalence of celiac disease: systematic review and Meta-analysis","volume":"16","author":"Singh","year":"2018","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.jim.2026.114077_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.ymgme.2024.109000","article-title":"Use of a mouse\u2013human chimeric anti-\u03b1-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease","volume":"144","author":"Tsukimura","year":"2025","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.jim.2026.114077_bb0125","unstructured":"M. Wadhwa, et al. Proposed 1st WHO erythropoietin antibody reference panel. WHO reference number: WHO\/BS\/2015.2265."},{"key":"10.1016\/j.jim.2026.114077_bb0130","article-title":"A novel chimeric anti-PA neutralizing antibody for postexposure prophylaxis and treatment of anthrax","volume":"5","author":"Xiong","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jim.2026.114077_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2025.113903","article-title":"Development of a chimeric monoclonal antibody as a potential diagnostic reference in PR3-ANCA detection","volume":"542","author":"Zhang","year":"2025","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.jim.2026.114077_bb0140","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.dld.2024.10.010","article-title":"Utilizing both IgA tissue transglutaminase and IgG-deamidated gliadin peptide antibodies offers accurate celiac disease diagnosis without duodenal biopsy","volume":"57","author":"Zingone","year":"2025","journal-title":"Dig. Liver Dis."}],"container-title":["Journal of Immunological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175926000530?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022175926000530?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T12:55:25Z","timestamp":1785243325000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022175926000530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":28,"alternative-id":["S0022175926000530"],"URL":"https:\/\/doi.org\/10.1016\/j.jim.2026.114077","relation":{},"ISSN":["0022-1759"],"issn-type":[{"value":"0022-1759","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of chimeric DGP-IgG antibodies as quality control for celiac disease diagnosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Immunological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jim.2026.114077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114077"}}