{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:15:48Z","timestamp":1790172948190,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1016\/j.jinf.2003.12.001","type":"journal-article","created":{"date-parts":[[2004,1,20]],"date-time":"2004-01-20T05:18:45Z","timestamp":1074575925000},"page":"229-235","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Hepatocyte growth factor (HGF) in patients with hepatitis B and meningitis"],"prefix":"10.1016","volume":"49","author":[{"given":"M.","family":"Ozden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kalkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Demirdag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Denk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.Sirri","family":"Kilic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jinf.2003.12.001_BIB1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1440-1746.1991.tb00897.x","article-title":"Hepatocyte growth factor: molecular structure and implications for a central role in liver regeneration","volume":"6","author":"Matsumoto","year":"1991","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jinf.2003.12.001_BIB2","doi-asserted-by":"crossref","first-page":"20114","DOI":"10.1016\/S0021-9258(19)88673-8","article-title":"Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer","volume":"267","author":"Naka","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jinf.2003.12.001_BIB3","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/0006-291X(84)91253-1","article-title":"Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats","volume":"122","author":"Nakamura","year":"1984","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jinf.2003.12.001_BIB4","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0014-4827(92)90095-P","article-title":"Regulation of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species","volume":"202","author":"Tajima","year":"1992","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jinf.2003.12.001_BIB5","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0140-6736(95)90279-1","article-title":"Hepatocyte growth factor; a multifunctional cytokine","volume":"345","author":"Boros","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.jinf.2003.12.001_BIB6","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/0006-291X(92)90844-B","article-title":"Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs","volume":"186","author":"Kono","year":"1992","journal-title":"Biochem Biophsy Res Commun"},{"key":"10.1016\/j.jinf.2003.12.001_BIB7","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/hep.1840210119","article-title":"Serum hepatocyte growth factor levels in liver diseases: clinical implications","volume":"21","author":"Shiota","year":"1995","journal-title":"Hepatology"},{"key":"10.1016\/j.jinf.2003.12.001_BIB8","doi-asserted-by":"crossref","first-page":"21212","DOI":"10.1016\/S0021-9258(19)36912-1","article-title":"Hepatocyte growth factor may act as a pulmonotrophic factor on lung regeneration after acute lung injury","volume":"268","author":"Yanagita","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jinf.2003.12.001_BIB9","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1046\/j.1523-1755.2000.00987.x","article-title":"Hepatocyte growth factor in renal failure: promise and reality","volume":"57","author":"Vargas","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.jinf.2003.12.001_BIB10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hep.1840130102","article-title":"Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme-linked immunosorbent assay","volume":"13","author":"Tsubouchi","year":"1991","journal-title":"Hepatology"},{"key":"10.1016\/j.jinf.2003.12.001_BIB11","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0140-6736(94)92025-7","article-title":"Hepatocyte proliferation as an indicator of outcome in acute alcoholic hepatitis","volume":"343","author":"Fang","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.jinf.2003.12.001_BIB12","first-page":"27","article-title":"Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions","volume":"3","author":"Matsumoto","year":"1992","journal-title":"Crit Rev Oncog"},{"key":"10.1016\/j.jinf.2003.12.001_BIB13","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0169-328X(95)00075-4","article-title":"Localization and functional coupling of HGF and c-Met\/HGF receptor in rat brain: implication as neurotrophic factor","volume":"32","author":"Honda","year":"1995","journal-title":"Mol Brain Res"},{"key":"10.1016\/j.jinf.2003.12.001_BIB14","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1083\/jcb.126.2.485","article-title":"Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain","volume":"126","author":"Jung","year":"1994","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jinf.2003.12.001_BIB15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1159\/000097202","article-title":"Passage of cytokines across the blood\u2013brain barrier","volume":"2","author":"Banks","year":"1995","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.jinf.2003.12.001_BIB16","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1006\/cyto.2001.0875","article-title":"Concentrations of hepatocyte growth factor in cerebrospinal fluid under normal and different pathological conditions","volume":"14","author":"Kern","year":"2001","journal-title":"Cytokine"},{"key":"10.1016\/j.jinf.2003.12.001_BIB17","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0022-1759(00)00252-0","article-title":"Development of highly sensitive enzyme-linked immunosorbent assays for hepatocyte growth factor\/scatter factor (HGF\/SF): determination of HGF\/SF in serum and urine from normal human subjects","volume":"244","author":"Ohnishi","year":"2000","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.jinf.2003.12.001_BIB18","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/hep.1840010511","article-title":"Formulation and application of a numerical scoring system for accessing histological activity in asymptomatic chronic active hepatitis","volume":"1","author":"Knodell","year":"1981","journal-title":"Hepatology"},{"key":"10.1016\/j.jinf.2003.12.001_BIB19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000050028","article-title":"Detection of serum and intrahepatic human hepatocyte growth factor in patients with type C liver diseases","volume":"44","author":"Yamagami","year":"2001","journal-title":"Intervirology"},{"key":"10.1016\/j.jinf.2003.12.001_BIB20","first-page":"35","article-title":"Clinical significance of serum hepatocyte growth factor levels in liver diseases","volume":"24","author":"Hioki","year":"1993","journal-title":"J Med"},{"key":"10.1016\/j.jinf.2003.12.001_BIB21","first-page":"157","article-title":"Serum hepatocyte growth factor in acute hepatic failure in comparison with acute hepatitis","volume":"85","author":"Shiota","year":"1994","journal-title":"Res Commun Mol Pathol Pharmacol"},{"key":"10.1016\/j.jinf.2003.12.001_BIB22","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1056\/NEJM199712113372406","article-title":"Hepatitis B virus infection","volume":"337","author":"Lee","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jinf.2003.12.001_BIB23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2174\/1568005014606053","article-title":"Antifibrogenic therapies in chronic HCV infection","volume":"1","author":"Shimizu","year":"2001","journal-title":"Curr Drug Targets Infect Disord"},{"key":"10.1016\/j.jinf.2003.12.001_BIB24","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/hep.1840190423","article-title":"Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression","volume":"19","author":"Shiota","year":"1994","journal-title":"Hepatology"},{"key":"10.1016\/j.jinf.2003.12.001_BIB25","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0006-8993(97)00958-X","article-title":"Hepatocyte growth factor (HGF\/SF) in Alzheimer's disease","volume":"779","author":"Fenton","year":"1998","journal-title":"Brain Res"},{"key":"10.1016\/j.jinf.2003.12.001_BIB26","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/(SICI)1097-0215(19960717)67:2<248::AID-IJC16>3.0.CO;2-7","article-title":"Scatter factor expression and regulation in human glial tumors","volume":"67","author":"Rosen","year":"1996","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jinf.2003.12.001_BIB27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1034\/j.1600-0404.2002.01125.x","article-title":"Hepatocyte growth factor in cerebrospinal fluid in neurologic disease","volume":"106","author":"Tsuboi","year":"2002","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.jinf.2003.12.001_BIB28","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1086\/315506","article-title":"Hepatocyte growth factor levels in cerebrospinal fluid: a comparison between acute bacterial and nonbacterial meningitis","volume":"181","author":"Nayeri","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jinf.2003.12.001_BIB29","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0006-8993(94)91250-5","article-title":"Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues","volume":"637","author":"Yamada","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/j.jinf.2003.12.001_BIB30","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0033-8389(22)00616-9","article-title":"Pathology and pathogenetic mechanisms in neurotuberculosis","volume":"33","author":"Dastur","year":"1995","journal-title":"Radiol Clin North Am"},{"key":"10.1016\/j.jinf.2003.12.001_BIB31","unstructured":"http:\/\/www.emedicine.com\/NEURO\/topic385.htm. Ramachandran TS, Kark PR. Tuberculous meningitis."}],"container-title":["Journal of Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445303002317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163445303002317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T15:26:18Z","timestamp":1758986778000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163445303002317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S0163445303002317"],"URL":"https:\/\/doi.org\/10.1016\/j.jinf.2003.12.001","relation":{},"ISSN":["0163-4453"],"issn-type":[{"value":"0163-4453","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hepatocyte growth factor (HGF) in patients with hepatitis B and meningitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jinf.2003.12.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 The British Infection Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}